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The map label for this gene is yciR [C]

Identifier: 120610219

GI number: 120610219

Start: 1699123

End: 1701186

Strand: Direct

Name: yciR [C]

Synonym: Aave_1534

Alternate gene names: 120610219

Gene position: 1699123-1701186 (Clockwise)

Preceding gene: 120610218

Following gene: 120610222

Centisome position: 31.74

GC content: 70.16

Gene sequence:

>2064_bases
GTGAACCGCCCGGCCGTCGATGTCGCGTGGCGGTCGCTGTTCGCGGGCCTGCGCGAAGCGCTCTGGCTGGTCGATGCGCA
GTCGCTGGACGTGGTGATGTGCAACCGGGCGGCGGCCGAGCTGGCCGGCCGGCCGCGGGAGGCCATGGAAGGGCGCCCGG
TGCACCTGCTGGCCAACACGCCCGAGGATCTCGCGTTCTGGTCGCAGGACCTGGCCGGGCTGCGGGCGGGTATCCATTCC
TATTCGGGCATGCTGCGCCCCGACGGGTCCCTCGTGCCGGTGGACCGCCGCGTCGCCGCCGTCGAGTCGCCCGAGGGCAT
GCCGCTGCTGGTGCTGGGCATGCTGGACCGCAGCGAGCAGGCGTCCATCCAGGACGAGCTCGAGCGGCTGCTTTCGGAGC
TGCGCGCCACGCTCGACTCCGCTGCCGACGGCATGCTGGTCTGCGACATGGGCGGCCGCGTGCGGGCCTTCAACCAGCGC
CTGGCCTGGCTGTGGAACATGCCGGACGACCTGCTCGTGCGGCGCGACGACGCGGCCGTGGAAGCGCACATGGCCGCGCA
GGTCACGGACGCCGACGCCTACCGCGCGCGGCTGCTGGGCATCGCGCAGTTCCCGGAGGAGGAAACCCTCGACATCCTGC
ACCTGCGTACGGGCACGGTGATCGAGCGCCGCTCGGTGCCGCAGATGAGCCATGGCCGTCCCATGGGCCGCGTGTATTCC
TTCCGCGACCTCACCCTGCAGCATGCCGCGCAAAAGCGGATCGAGCAGCTGGCGTACAGCGACGTGCTCACGGGCCTGCC
CAACCGCCTGCTGCTGTCGCGCTGCGTCGCCTCGGCGCTGGAAACCGCGCGCGCGCAGGGCGGCGGCTTCGCCATCCTGT
TCATCGACCTCGACCGTTTCAAGATCATCAACGATTCGCTGGGGCATCTCTTCGGCGACCGGGTGCTGCAGCTCGTGGCG
CAGCGCCTGCGGGGCTGCCTGCGGCAGAACGACATGCTGTGCCGCCTGGGAGGCGACGAGTTCGTGCTCCACCTGGATGA
GGGTGACGCGTCCATGGCCGAGGCCGTGGCGTGCCGCATCCTGGAGGAGATGCGCCAGCCCTTCATGCTCGACGGCATGG
GCTTTTCCATCCAGTGCAGCATCGGCATCGCGCTGCACCCGCGGGACGGCGAGACGCTGGACGACCTGATCAAGCAGGCG
GACACCGCCATGTACCGGGTCAAGGAGCGCGGCCGGGGCAGCTACGGGTTCTACCACCCGCAGATGAATGCCGACATGCT
CTCGCGCATGCAACTGGAGCACGCGATGCGCCAGGCGCTGGACCGCGGCGATTTCGCCGTGCACTACCAGCCGCAGGTGG
AGATGGCCTCGGGCCGCGTGGTGGGCGCCGAAGCCCTGCTGCGCTGGAACGATCCCGGGCTGGGCGCGGTGTCGCCGGGC
GTCTTCATCCCGCTGGCGGAAGAGTCGGGCTATATCGTGACCCTGGGAGCCTGGGTGCTGGAGCAGGCGATCCGCGAGGC
GGCCGAGTGGATGCGCGCCGGCACGCCCCTGGTGGTGGCGGTGAACGTGTCCGCGCTGGAGTTCCGGCAGTCCGGCTTCG
TGGAGCGCCTCGTGGCGCTGCTGCGCAGCCACGGGCTGCCGGCATCGCTGCTGGAGCTGGAACTGACCGAGACGATCCTG
CTGCAGGATGCGCAGGAAATGGCGCAGCGCCTCGCGGCCCTGGCCGAGCTGGGCGTGGGCCTGTCGATCGACGATTTCGG
CACGGGCTATTCGAGCCTGGCCTATCTCAAGAAGCTCCGCATCCACAAGCTCAAGATCGACCAGTCGTTCGTGCGCGGCC
TGCCGGACGACGAGAGCGACCGGGCGATCATCGAGGCGATCGTGCACATCGGCCGGGCGCTGCGCATCCGGGTGGTGGCC
GAGGGCGTCGAGACGCCGCAGCAGCGCGAGGCGCTGCAGGCCTTGCAGTGCCACTACTTCCAGGGTTTCCTGGTGGCACC
GGGGTTGCCTGCGGAGGCTTTCCGCGCCCTGGTCGCGCGGGATGGCTGCGAACCACCGGCATGA

Upstream 100 bases:

>100_bases
CGCAGCTGCCGCGCGACGCGCTGGACTACCTCTCTCCGTGCAAACGCATCTGCTATTTCTTCGAGAGGGCGCTGGTGGTT
GGCGCGGACGAGGTGCCGGA

Downstream 100 bases:

>100_bases
GCCCGCTGCAGCGGGCCGTCATCGCGGGCAGGACCGCAATGCAAAAGCGCCGCGGGAATGCTGCGGCGCTCGGGGGAAAA
GGTGTCCGCAGTAGCCACCG

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 687; Mature: 687

Protein sequence:

>687_residues
MNRPAVDVAWRSLFAGLREALWLVDAQSLDVVMCNRAAAELAGRPREAMEGRPVHLLANTPEDLAFWSQDLAGLRAGIHS
YSGMLRPDGSLVPVDRRVAAVESPEGMPLLVLGMLDRSEQASIQDELERLLSELRATLDSAADGMLVCDMGGRVRAFNQR
LAWLWNMPDDLLVRRDDAAVEAHMAAQVTDADAYRARLLGIAQFPEEETLDILHLRTGTVIERRSVPQMSHGRPMGRVYS
FRDLTLQHAAQKRIEQLAYSDVLTGLPNRLLLSRCVASALETARAQGGGFAILFIDLDRFKIINDSLGHLFGDRVLQLVA
QRLRGCLRQNDMLCRLGGDEFVLHLDEGDASMAEAVACRILEEMRQPFMLDGMGFSIQCSIGIALHPRDGETLDDLIKQA
DTAMYRVKERGRGSYGFYHPQMNADMLSRMQLEHAMRQALDRGDFAVHYQPQVEMASGRVVGAEALLRWNDPGLGAVSPG
VFIPLAEESGYIVTLGAWVLEQAIREAAEWMRAGTPLVVAVNVSALEFRQSGFVERLVALLRSHGLPASLLELELTETIL
LQDAQEMAQRLAALAELGVGLSIDDFGTGYSSLAYLKKLRIHKLKIDQSFVRGLPDDESDRAIIEAIVHIGRALRIRVVA
EGVETPQQREALQALQCHYFQGFLVAPGLPAEAFRALVARDGCEPPA

Sequences:

>Translated_687_residues
MNRPAVDVAWRSLFAGLREALWLVDAQSLDVVMCNRAAAELAGRPREAMEGRPVHLLANTPEDLAFWSQDLAGLRAGIHS
YSGMLRPDGSLVPVDRRVAAVESPEGMPLLVLGMLDRSEQASIQDELERLLSELRATLDSAADGMLVCDMGGRVRAFNQR
LAWLWNMPDDLLVRRDDAAVEAHMAAQVTDADAYRARLLGIAQFPEEETLDILHLRTGTVIERRSVPQMSHGRPMGRVYS
FRDLTLQHAAQKRIEQLAYSDVLTGLPNRLLLSRCVASALETARAQGGGFAILFIDLDRFKIINDSLGHLFGDRVLQLVA
QRLRGCLRQNDMLCRLGGDEFVLHLDEGDASMAEAVACRILEEMRQPFMLDGMGFSIQCSIGIALHPRDGETLDDLIKQA
DTAMYRVKERGRGSYGFYHPQMNADMLSRMQLEHAMRQALDRGDFAVHYQPQVEMASGRVVGAEALLRWNDPGLGAVSPG
VFIPLAEESGYIVTLGAWVLEQAIREAAEWMRAGTPLVVAVNVSALEFRQSGFVERLVALLRSHGLPASLLELELTETIL
LQDAQEMAQRLAALAELGVGLSIDDFGTGYSSLAYLKKLRIHKLKIDQSFVRGLPDDESDRAIIEAIVHIGRALRIRVVA
EGVETPQQREALQALQCHYFQGFLVAPGLPAEAFRALVARDGCEPPA
>Mature_687_residues
MNRPAVDVAWRSLFAGLREALWLVDAQSLDVVMCNRAAAELAGRPREAMEGRPVHLLANTPEDLAFWSQDLAGLRAGIHS
YSGMLRPDGSLVPVDRRVAAVESPEGMPLLVLGMLDRSEQASIQDELERLLSELRATLDSAADGMLVCDMGGRVRAFNQR
LAWLWNMPDDLLVRRDDAAVEAHMAAQVTDADAYRARLLGIAQFPEEETLDILHLRTGTVIERRSVPQMSHGRPMGRVYS
FRDLTLQHAAQKRIEQLAYSDVLTGLPNRLLLSRCVASALETARAQGGGFAILFIDLDRFKIINDSLGHLFGDRVLQLVA
QRLRGCLRQNDMLCRLGGDEFVLHLDEGDASMAEAVACRILEEMRQPFMLDGMGFSIQCSIGIALHPRDGETLDDLIKQA
DTAMYRVKERGRGSYGFYHPQMNADMLSRMQLEHAMRQALDRGDFAVHYQPQVEMASGRVVGAEALLRWNDPGLGAVSPG
VFIPLAEESGYIVTLGAWVLEQAIREAAEWMRAGTPLVVAVNVSALEFRQSGFVERLVALLRSHGLPASLLELELTETIL
LQDAQEMAQRLAALAELGVGLSIDDFGTGYSSLAYLKKLRIHKLKIDQSFVRGLPDDESDRAIIEAIVHIGRALRIRVVA
EGVETPQQREALQALQCHYFQGFLVAPGLPAEAFRALVARDGCEPPA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=443, Percent_Identity=37.2460496613996, Blast_Score=302, Evalue=4e-83,
Organism=Escherichia coli, GI87081921, Length=427, Percent_Identity=36.0655737704918, Blast_Score=272, Evalue=6e-74,
Organism=Escherichia coli, GI226510982, Length=442, Percent_Identity=31.447963800905, Blast_Score=182, Evalue=6e-47,
Organism=Escherichia coli, GI87081743, Length=250, Percent_Identity=34, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1790496, Length=239, Percent_Identity=32.2175732217573, Blast_Score=147, Evalue=3e-36,
Organism=Escherichia coli, GI87081980, Length=258, Percent_Identity=36.046511627907, Blast_Score=142, Evalue=8e-35,
Organism=Escherichia coli, GI1788502, Length=253, Percent_Identity=35.1778656126482, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI87081845, Length=234, Percent_Identity=36.7521367521368, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI1788849, Length=432, Percent_Identity=27.5462962962963, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786507, Length=261, Percent_Identity=31.8007662835249, Blast_Score=133, Evalue=5e-32,
Organism=Escherichia coli, GI1787055, Length=242, Percent_Identity=31.404958677686, Blast_Score=126, Evalue=5e-30,
Organism=Escherichia coli, GI1788381, Length=324, Percent_Identity=29.6296296296296, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI87082096, Length=426, Percent_Identity=26.7605633802817, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI87081881, Length=172, Percent_Identity=35.4651162790698, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI145693134, Length=158, Percent_Identity=35.4430379746835, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI87081977, Length=169, Percent_Identity=33.1360946745562, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1786584, Length=175, Percent_Identity=28, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787262, Length=169, Percent_Identity=30.1775147928994, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081974, Length=155, Percent_Identity=32.9032258064516, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787816, Length=163, Percent_Identity=33.1288343558282, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082007, Length=175, Percent_Identity=30.8571428571429, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787410, Length=237, Percent_Identity=26.5822784810127, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1788956, Length=166, Percent_Identity=34.3373493975904, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788085, Length=173, Percent_Identity=30.0578034682081, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787802, Length=203, Percent_Identity=27.0935960591133, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 75863; Mature: 75863

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRPAVDVAWRSLFAGLREALWLVDAQSLDVVMCNRAAAELAGRPREAMEGRPVHLLANT
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCCHHHHCCCCEEEECCC
PEDLAFWSQDLAGLRAGIHSYSGMLRPDGSLVPVDRRVAAVESPEGMPLLVLGMLDRSEQ
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHEECCCCCCCCEEEEEECCCCCC
ASIQDELERLLSELRATLDSAADGMLVCDMGGRVRAFNQRLAWLWNMPDDLLVRRDDAAV
CCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCHHHEEECCCHHH
EAHMAAQVTDADAYRARLLGIAQFPEEETLDILHLRTGTVIERRSVPQMSHGRPMGRVYS
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCHHHHH
FRDLTLQHAAQKRIEQLAYSDVLTGLPNRLLLSRCVASALETARAQGGGFAILFIDLDRF
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHH
KIINDSLGHLFGDRVLQLVAQRLRGCLRQNDMLCRLGGDEFVLHLDEGDASMAEAVACRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHH
LEEMRQPFMLDGMGFSIQCSIGIALHPRDGETLDDLIKQADTAMYRVKERGRGSYGFYHP
HHHHCCCEEECCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECC
QMNADMLSRMQLEHAMRQALDRGDFAVHYQPQVEMASGRVVGAEALLRWNDPGLGAVSPG
CCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCEECCCCCEEEHHHEEEECCCCCCCCCCC
VFIPLAEESGYIVTLGAWVLEQAIREAAEWMRAGTPLVVAVNVSALEFRQSGFVERLVAL
EEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHCCHHHHHHHH
LRSHGLPASLLELELTETILLQDAQEMAQRLAALAELGVGLSIDDFGTGYSSLAYLKKLR
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHH
IHKLKIDQSFVRGLPDDESDRAIIEAIVHIGRALRIRVVAEGVETPQQREALQALQCHYF
HHHEECCHHHHCCCCCCCCHHHHHHHHHHCCHHEEEEEEECCCCCHHHHHHHHHHHHHHH
QGFLVAPGLPAEAFRALVARDGCEPPA
CCEEECCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNRPAVDVAWRSLFAGLREALWLVDAQSLDVVMCNRAAAELAGRPREAMEGRPVHLLANT
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCCHHHHCCCCEEEECCC
PEDLAFWSQDLAGLRAGIHSYSGMLRPDGSLVPVDRRVAAVESPEGMPLLVLGMLDRSEQ
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHEECCCCCCCCEEEEEECCCCCC
ASIQDELERLLSELRATLDSAADGMLVCDMGGRVRAFNQRLAWLWNMPDDLLVRRDDAAV
CCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCHHHEEECCCHHH
EAHMAAQVTDADAYRARLLGIAQFPEEETLDILHLRTGTVIERRSVPQMSHGRPMGRVYS
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCHHHHH
FRDLTLQHAAQKRIEQLAYSDVLTGLPNRLLLSRCVASALETARAQGGGFAILFIDLDRF
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHH
KIINDSLGHLFGDRVLQLVAQRLRGCLRQNDMLCRLGGDEFVLHLDEGDASMAEAVACRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHH
LEEMRQPFMLDGMGFSIQCSIGIALHPRDGETLDDLIKQADTAMYRVKERGRGSYGFYHP
HHHHCCCEEECCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECC
QMNADMLSRMQLEHAMRQALDRGDFAVHYQPQVEMASGRVVGAEALLRWNDPGLGAVSPG
CCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCEECCCCCEEEHHHEEEECCCCCCCCCCC
VFIPLAEESGYIVTLGAWVLEQAIREAAEWMRAGTPLVVAVNVSALEFRQSGFVERLVAL
EEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHCCHHHHHHHH
LRSHGLPASLLELELTETILLQDAQEMAQRLAALAELGVGLSIDDFGTGYSSLAYLKKLR
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHH
IHKLKIDQSFVRGLPDDESDRAIIEAIVHIGRALRIRVVAEGVETPQQREALQALQCHYF
HHHEECCHHHHCCCCCCCCHHHHHHHHHHCCHHEEEEEEECCCCCHHHHHHHHHHHHHHH
QGFLVAPGLPAEAFRALVARDGCEPPA
CCEEECCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]