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The map label for this gene is lgt

Identifier: 120610194

GI number: 120610194

Start: 1673106

End: 1673918

Strand: Direct

Name: lgt

Synonym: Aave_1509

Alternate gene names: 120610194

Gene position: 1673106-1673918 (Clockwise)

Preceding gene: 120610193

Following gene: 120610195

Centisome position: 31.26

GC content: 68.27

Gene sequence:

>813_bases
ATGCTCATGTACCCGCATATCGATCCCATCGCCCTGCAGATCGGGCCGCTCGCCATCCACTGGTACGGCCTGACCTACCT
GGCCGCGTTCGGCCTCTTCATGTTCCTGGGCACGCGCCGGTTGCGGCACGAGCCGTATGCCTCGCTCACCGGCGCGCAGG
CCTGGACCCGCAAGGACGTGGAGGACATCCTCTTCCTGGGCGTGCTGGGCGTGGTGGTCGGCGGGCGGCTGGGCTACTGC
CTCTTCTACAAGCCGGGCTACTACCTGTCGCATCCGCTGGAGATCTTCTATATCTGGCAGGGCGGCATGAGCTTCCACGG
CGGGCTGCTGGGGGTGATCGCGTCGATGGTGTGGTTCGCCCGCTCGCGCCACCGGCCCTGGCTGCAGGTGGCGGACTTCG
TGGCACCCTGCGTGCCCACGGGGCTCGCCGCCGGGCGGGTGGGCAACTTCATCAACGGCGAACTCTGGGGGCGGTTCTGC
GACCCGTCGCTGCCCTGGGGCATGGTGTTCCCGCAGAGCGGCTCGATGCTGCCGCGCCATCCTTCGCAGGTGTACCAGTT
CCTGATGGAAGGCCTGCTGCTGTTCGTGCTGCTGTGGCTGTATGCGCGGCGCGAGCGCCGGCAGGGCGAGGTGGCGGCGG
CGTTCCTCGTGGGATACGGGTGCTTCCGTTTCATCGCCGAATATTTCCGCGAGCCGGACGCGTTCCTCGGCATCCTGTCG
CTGGGCATGAGCATGGGCCAATGGCTCTGCGTGCCGATGATCGTGGCCGGGGTGCTGCTGTGGGTGTGGGCGCGGCGGCA
GCCGGCGCGCTGA

Upstream 100 bases:

>100_bases
GCGCAGTCAGTGAGGTGGCGCAGGCCAGGCTCCCTCTCCCGGTGGGCAGTGGGGCGGGCCCCGCTGATGCGGCGGCGCGG
CGGGCACAATACCGCCCACC

Downstream 100 bases:

>100_bases
GAGCTCCCCGGCCCCGAAGCCGGGAGGCGGGCTCCGTCTCCGGGTAGAGCGGGTGCCCGCCCGGCGTCTGATACCGGTGG
CGCACCGGGTGGCGCACTCG

Product: prolipoprotein diacylglyceryl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MLMYPHIDPIALQIGPLAIHWYGLTYLAAFGLFMFLGTRRLRHEPYASLTGAQAWTRKDVEDILFLGVLGVVVGGRLGYC
LFYKPGYYLSHPLEIFYIWQGGMSFHGGLLGVIASMVWFARSRHRPWLQVADFVAPCVPTGLAAGRVGNFINGELWGRFC
DPSLPWGMVFPQSGSMLPRHPSQVYQFLMEGLLLFVLLWLYARRERRQGEVAAAFLVGYGCFRFIAEYFREPDAFLGILS
LGMSMGQWLCVPMIVAGVLLWVWARRQPAR

Sequences:

>Translated_270_residues
MLMYPHIDPIALQIGPLAIHWYGLTYLAAFGLFMFLGTRRLRHEPYASLTGAQAWTRKDVEDILFLGVLGVVVGGRLGYC
LFYKPGYYLSHPLEIFYIWQGGMSFHGGLLGVIASMVWFARSRHRPWLQVADFVAPCVPTGLAAGRVGNFINGELWGRFC
DPSLPWGMVFPQSGSMLPRHPSQVYQFLMEGLLLFVLLWLYARRERRQGEVAAAFLVGYGCFRFIAEYFREPDAFLGILS
LGMSMGQWLCVPMIVAGVLLWVWARRQPAR
>Mature_270_residues
MLMYPHIDPIALQIGPLAIHWYGLTYLAAFGLFMFLGTRRLRHEPYASLTGAQAWTRKDVEDILFLGVLGVVVGGRLGYC
LFYKPGYYLSHPLEIFYIWQGGMSFHGGLLGVIASMVWFARSRHRPWLQVADFVAPCVPTGLAAGRVGNFINGELWGRFC
DPSLPWGMVFPQSGSMLPRHPSQVYQFLMEGLLLFVLLWLYARRERRQGEVAAAFLVGYGCFRFIAEYFREPDAFLGILS
LGMSMGQWLCVPMIVAGVLLWVWARRQPAR

Specific function: Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins

COG id: COG0682

COG function: function code M; Prolipoprotein diacylglyceryltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lgt family

Homologues:

Organism=Escherichia coli, GI1789192, Length=291, Percent_Identity=49.1408934707904, Blast_Score=273, Evalue=1e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LGT_ACIAC (A1TMB0)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_969872.1
- STRING:   A1TMB0
- GeneID:   4669215
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_1509
- NMPDR:   fig|397945.5.peg.1326
- eggNOG:   COG0682
- HOGENOM:   HBG450278
- OMA:   NPIAFSL
- PhylomeDB:   A1TMB0
- ProtClustDB:   PRK00052
- BioCyc:   AAVE397945:AAVE_1509-MONOMER
- HAMAP:   MF_01147
- InterPro:   IPR001640
- TIGRFAMs:   TIGR00544

Pfam domain/function: PF01790 LGT

EC number: 2.4.99.- [C]

Molecular weight: Translated: 30620; Mature: 30620

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS01311 LGT

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12a84fb0)-; HASH(0x13195554)-; HASH(0x1328abc0)-; HASH(0x1328ae24)-; HASH(0x132a7028)-; HASH(0x13204dfc)-; HASH(0x13204e14)-;

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
>Mature Secondary Structure
MLMYPHIDPIALQIGPLAIHWYGLTYLAAFGLFMFLGTRRLRHEPYASLTGAQAWTRKDV
CCCCCCCCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHH
EDILFLGVLGVVVGGRLGYCLFYKPGYYLSHPLEIFYIWQGGMSFHGGLLGVIASMVWFA
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHH
RSRHRPWLQVADFVAPCVPTGLAAGRVGNFINGELWGRFCDPSLPWGMVFPQSGSMLPRH
HHCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHCCCCCCCCCCCEEECCCCCCCCCC
PSQVYQFLMEGLLLFVLLWLYARRERRQGEVAAAFLVGYGCFRFIAEYFREPDAFLGILS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LGMSMGQWLCVPMIVAGVLLWVWARRQPAR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA