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The map label for this gene is yjiA [H]

Identifier: 120609501

GI number: 120609501

Start: 872112

End: 873191

Strand: Direct

Name: yjiA [H]

Synonym: Aave_0807

Alternate gene names: 120609501

Gene position: 872112-873191 (Clockwise)

Preceding gene: 120609499

Following gene: 120609502

Centisome position: 16.29

GC content: 64.44

Gene sequence:

>1080_bases
ATGTCCCTCATTCCGACCACCATCCTCACGGGCTTCCTGGGCTCGGGCAAGACCACCCTGCTCAAGCGCGTGCTGACCGA
ATCGCACGGCCAGAAGATCGCCGTCATCGAGAACGAATTCGGCGAGGAGAACATCGACAACGACATCCTCGTGACGGATT
CCAAGGAGCAGATCGTGCAGATGAGCAACGGCTGCATCTGCTGCACCATCCGGGAAGACCTGCGCGAGACGTTGCAGTTG
CTGGCCGCCAAGCGCCGCAAGGGGCTGCTGGACTTCGACCGCGTGGTGATCGAGACCACCGGCCTGGCCGACCCGGGGCC
CGTGGCGCAGACCTTCTTCATGGACGAGGAGATCGCCGAAACCTACCTCATCGACTCCATCATCACCCTGGTGGATGCCA
AGCACGCCGCCCAGCAGCTGAACGACCGGCAGGAAGCGCGTCGCCAGGTGGGCTTCGCCGACCAGATCTTCCTCTCCAAG
ACCGACCTGGTGCCGGCGGAGGAGACCGACGCGCTGATCCACCGCCTCAAGCACATGAATCCGCGCGCCCCGATCAAGGC
GGTGCATTTCGGCGAGGTGCCCGTCGCCGAGGTGCTGGACCTGCGCGGCTTCAACCTGAACGCCAAGCTCGACATCGACC
CCGACTTCCTGAAGGAAGAGGACGACCACGGCCATGACCACGACCATGGGCACGACCACCACGGCCATGACCACGAACAC
GGCGAGCACTGCAGCCATCCCTCGCACCAGCACGGCGGCCACGGCCACCACCATCACCATGACGACGACGTGAAAAGCTT
CGTCTACCGCGCCGACCGTCCGTTCGACCCGGCCAAGCTGGAGGATTTCCTGGGCGCCATCGTCAACATCTACGGCCCCC
GCATGCTGCGCTACAAGGGCGTGCTGCACATGAAGGGCACCGAGCGCAAGGTCATCTTCCAGGGCGTGCACCAGCTCATG
GGCAGCGACCTGGGCCCGCAGTGGGCCGAGGACGAGAAGCGCCAGAGCAAGATGGTCTTCATCGGCATCGAGCTGCCGCA
GGACATCTTCCAGCAGGGGCTGGAACAGTGCCTGGCCTGA

Upstream 100 bases:

>100_bases
CTTTGGCTAGCGAAATCCATGGGGTGTTGACAGCCTCGCTAAACTTTTGGGAAGGTGTGCCGTGCCGGCACCCTCCACCT
TCCGAAAGCGTTTGCCGACC

Downstream 100 bases:

>100_bases
GCCGCTCCCGGGCCGGACGCCGCGGCCGGTTTGTAGGATAACCACTACTTCGCGGGGGGCGGCCGCGCAGGCGCGAAATC
GGCCGATACAATCGCGCCCC

Product: cobalamin synthesis protein, P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MSLIPTTILTGFLGSGKTTLLKRVLTESHGQKIAVIENEFGEENIDNDILVTDSKEQIVQMSNGCICCTIREDLRETLQL
LAAKRRKGLLDFDRVVIETTGLADPGPVAQTFFMDEEIAETYLIDSIITLVDAKHAAQQLNDRQEARRQVGFADQIFLSK
TDLVPAEETDALIHRLKHMNPRAPIKAVHFGEVPVAEVLDLRGFNLNAKLDIDPDFLKEEDDHGHDHDHGHDHHGHDHEH
GEHCSHPSHQHGGHGHHHHHDDDVKSFVYRADRPFDPAKLEDFLGAIVNIYGPRMLRYKGVLHMKGTERKVIFQGVHQLM
GSDLGPQWAEDEKRQSKMVFIGIELPQDIFQQGLEQCLA

Sequences:

>Translated_359_residues
MSLIPTTILTGFLGSGKTTLLKRVLTESHGQKIAVIENEFGEENIDNDILVTDSKEQIVQMSNGCICCTIREDLRETLQL
LAAKRRKGLLDFDRVVIETTGLADPGPVAQTFFMDEEIAETYLIDSIITLVDAKHAAQQLNDRQEARRQVGFADQIFLSK
TDLVPAEETDALIHRLKHMNPRAPIKAVHFGEVPVAEVLDLRGFNLNAKLDIDPDFLKEEDDHGHDHDHGHDHHGHDHEH
GEHCSHPSHQHGGHGHHHHHDDDVKSFVYRADRPFDPAKLEDFLGAIVNIYGPRMLRYKGVLHMKGTERKVIFQGVHQLM
GSDLGPQWAEDEKRQSKMVFIGIELPQDIFQQGLEQCLA
>Mature_358_residues
SLIPTTILTGFLGSGKTTLLKRVLTESHGQKIAVIENEFGEENIDNDILVTDSKEQIVQMSNGCICCTIREDLRETLQLL
AAKRRKGLLDFDRVVIETTGLADPGPVAQTFFMDEEIAETYLIDSIITLVDAKHAAQQLNDRQEARRQVGFADQIFLSKT
DLVPAEETDALIHRLKHMNPRAPIKAVHFGEVPVAEVLDLRGFNLNAKLDIDPDFLKEEDDHGHDHDHGHDHHGHDHEHG
EHCSHPSHQHGGHGHHHHHDDDVKSFVYRADRPFDPAKLEDFLGAIVNIYGPRMLRYKGVLHMKGTERKVIFQGVHQLMG
SDLGPQWAEDEKRQSKMVFIGIELPQDIFQQGLEQCLA

Specific function: Binds GTP. May function as GTP-dependent regulator [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI126722884, Length=361, Percent_Identity=31.3019390581717, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI33469141, Length=361, Percent_Identity=31.3019390581717, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI146231952, Length=361, Percent_Identity=31.5789473684211, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI148727351, Length=361, Percent_Identity=31.3019390581717, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI223941779, Length=361, Percent_Identity=30.7479224376731, Blast_Score=168, Evalue=7e-42,
Organism=Homo sapiens, GI223941776, Length=351, Percent_Identity=30.1994301994302, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI119120938, Length=164, Percent_Identity=38.4146341463415, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI87082430, Length=349, Percent_Identity=39.541547277937, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1788499, Length=176, Percent_Identity=33.5227272727273, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324356, Length=225, Percent_Identity=30.2222222222222, Blast_Score=122, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 40515; Mature: 40384

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIPTTILTGFLGSGKTTLLKRVLTESHGQKIAVIENEFGEENIDNDILVTDSKEQIVQ
CCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEECCHHHHHH
MSNGCICCTIREDLRETLQLLAAKRRKGLLDFDRVVIETTGLADPGPVAQTFFMDEEIAE
HCCCEEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHEEECCCCCCCCHHHHHHHHHHHHH
TYLIDSIITLVDAKHAAQQLNDRQEARRQVGFADQIFLSKTDLVPAEETDALIHRLKHMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCC
PRAPIKAVHFGEVPVAEVLDLRGFNLNAKLDIDPDFLKEEDDHGHDHDHGHDHHGHDHEH
CCCCEEEEECCCCCHHHHHHCCCCCCCEEECCCHHHHCCCCCCCCCCCCCCCCCCCCCCC
GEHCSHPSHQHGGHGHHHHHDDDVKSFVYRADRPFDPAKLEDFLGAIVNIYGPRMLRYKG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHCC
VLHMKGTERKVIFQGVHQLMGSDLGPQWAEDEKRQSKMVFIGIELPQDIFQQGLEQCLA
EEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCEEEEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SLIPTTILTGFLGSGKTTLLKRVLTESHGQKIAVIENEFGEENIDNDILVTDSKEQIVQ
CCCHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEECCHHHHHH
MSNGCICCTIREDLRETLQLLAAKRRKGLLDFDRVVIETTGLADPGPVAQTFFMDEEIAE
HCCCEEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHEEECCCCCCCCHHHHHHHHHHHHH
TYLIDSIITLVDAKHAAQQLNDRQEARRQVGFADQIFLSKTDLVPAEETDALIHRLKHMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCC
PRAPIKAVHFGEVPVAEVLDLRGFNLNAKLDIDPDFLKEEDDHGHDHDHGHDHHGHDHEH
CCCCEEEEECCCCCHHHHHHCCCCCCCEEECCCHHHHCCCCCCCCCCCCCCCCCCCCCCC
GEHCSHPSHQHGGHGHHHHHDDDVKSFVYRADRPFDPAKLEDFLGAIVNIYGPRMLRYKG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHCC
VLHMKGTERKVIFQGVHQLMGSDLGPQWAEDEKRQSKMVFIGIELPQDIFQQGLEQCLA
EEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCEEEEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 1650347 [H]