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The map label for this gene is mdtJ [H]

Identifier: 120609414

GI number: 120609414

Start: 773839

End: 774210

Strand: Direct

Name: mdtJ [H]

Synonym: Aave_0718

Alternate gene names: 120609414

Gene position: 773839-774210 (Clockwise)

Preceding gene: 120609413

Following gene: 120609415

Centisome position: 14.46

GC content: 57.26

Gene sequence:

>372_bases
ATGGCTATCCGCTTAACGCTTCAACCCTGGCTGTTTCTTCTGGCGGCCGTCGCTTCAGAGGTCGTAGGTGTGACCACGAT
GAAGTTGGTGGCCCAGGAGCATGACTGGGGTGCGCTCTTGTTCATGTACTCCACGATCGGCCTGTCGTTCGCGTTTCTCG
CAATGGCGATGAAACAGATTCCCATGGCCGTGGCCTATGCCACCTGGGAGACGTTGGGACTGTTGGCGATTGCGTTCATC
GGCTACCGCTACTTCGGGGAAAGCATGAGCGCCGGCAAGTTGCTCGGCATGAGCGTGCTGATTGTTGGGGTTGTTCTTGT
TAACGCGGATGGCGCGCACGCTAGAGAACGGACATGCAGAACGCCTACTTGA

Upstream 100 bases:

>100_bases
GCTGTTCATCGGTGCGCTGGTGACGGCACGCTTGCTGCGCTGCTACGGCCCAGGCACCGCGTCGGCCTCGGCAGTGCACT
GATCGCATGAGGCATCCCTG

Downstream 100 bases:

>100_bases
TTCACTACGCCTGGATGTTGGTGGCCATCCTGCTGGAAGTGGCTGCCAACATCTTTGTATATGCATCCCAGGGGTGGAGC
CCCCCGCGTCAGAATAGTTG

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 123; Mature: 122

Protein sequence:

>123_residues
MAIRLTLQPWLFLLAAVASEVVGVTTMKLVAQEHDWGALLFMYSTIGLSFAFLAMAMKQIPMAVAYATWETLGLLAIAFI
GYRYFGESMSAGKLLGMSVLIVGVVLVNADGAHARERTCRTPT

Sequences:

>Translated_123_residues
MAIRLTLQPWLFLLAAVASEVVGVTTMKLVAQEHDWGALLFMYSTIGLSFAFLAMAMKQIPMAVAYATWETLGLLAIAFI
GYRYFGESMSAGKLLGMSVLIVGVVLVNADGAHARERTCRTPT
>Mature_122_residues
AIRLTLQPWLFLLAAVASEVVGVTTMKLVAQEHDWGALLFMYSTIGLSFAFLAMAMKQIPMAVAYATWETLGLLAIAFIG
YRYFGESMSAGKLLGMSVLIVGVVLVNADGAHARERTCRTPT

Specific function: Catalyzes the excretion of spermidine [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtJ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787884, Length=107, Percent_Identity=36.4485981308411, Blast_Score=74, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 13346; Mature: 13215

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIRLTLQPWLFLLAAVASEVVGVTTMKLVAQEHDWGALLFMYSTIGLSFAFLAMAMKQI
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
PMAVAYATWETLGLLAIAFIGYRYFGESMSAGKLLGMSVLIVGVVLVNADGAHARERTCR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHCCCC
TPT
CCC
>Mature Secondary Structure 
AIRLTLQPWLFLLAAVASEVVGVTTMKLVAQEHDWGALLFMYSTIGLSFAFLAMAMKQI
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
PMAVAYATWETLGLLAIAFIGYRYFGESMSAGKLLGMSVLIVGVVLVNADGAHARERTCR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHCCCC
TPT
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA