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The map label for this gene is surA [H]

Identifier: 120609364

GI number: 120609364

Start: 723506

End: 724417

Strand: Direct

Name: surA [H]

Synonym: Aave_0665

Alternate gene names: 120609364

Gene position: 723506-724417 (Clockwise)

Preceding gene: 120609363

Following gene: 120609365

Centisome position: 13.52

GC content: 75.44

Gene sequence:

>912_bases
ATGTCCTGCACCTGCCAAGACTCTCCTGCCTCCACCGGCTGCCGCGGCTCCGGTTCCGGGGGCGATCTGGATCACGCCGT
CGGCATCGCCCCCGGCTTCGATGCGGACCTTCCCGGGCACGGTCCCGGCTCGCCCGCGCCGGCCGTCCCGGGCCCCGTTG
CCTCGGTCAACGGCGTCGCGCTGCACCGCGCGGATGATGCGCCCGATGCGGACACGCTGCGCCAGCGTGCCTGCACCGAG
CTGCTGCGCCAGGCCGCCCAGCGCGCCGGCCTGTTGGCGGCCGATGACGCGCCCGCCGACGACGGCACCACCTCCGAAGC
CGCGACGCAGGCCATCGAGGCACTGCTGGAGCAGGCCCTCGCCGTGCCCGACCCGTCGGAGGATGCCTGCCGCCGCCACT
ACGAGGCGCACACCGCGCGCTACCGCGACGGCGAGCGCGTGCACCTGCGGCACGTCCTCTATGCCGTGACGCCGGGCGTG
GACGTGCAGCGCCTGCGCGAACGCGCCGAAGCCGAACTGCTGCAACTGCGCTGCGCCCACGACGGAGGCGAGGCCTTCGC
GCGTGCCGCACGGCAATGGTCCAACTGCCCTACCGGCGCGGAGGGTGGCGACCTGGGCTGGCTGGCGCGCGGCGACTGCG
CGCCCGAGTTCGCGCGCGAGGTGTTCGGCGCGCAGGAGGTCGGCGTGCTGCCGCGCCTGGTGCACAGCCGCTTCGGCCTG
CACGTGGTGGAGGTGGTGGCGCGCGACGCGGGCCGCCAGCGCGGCTACGGCGAGGTGCGCGAGGCCGTCGCGCTCGCGCT
GCGCCAGCAGTCCTGGGTGAACGCGCTGCGGCAGTACCTGCAGGTGCTCGCGGGCGAAGCCGCGCTGCAGGGCGTGGACC
TGGACGGCGCCGACACGCCGCTCGTGCAGTAG

Upstream 100 bases:

>100_bases
ACCTGCCTGGCCAGCCCAGCGCCGTGCCGTCGCCCGACGTGGCCCGCGCCATCGACAACCCGCGCGCCACGCGCTAGCGG
CCTTCGCACCGGAGCACACC

Downstream 100 bases:

>100_bases
CGTTCCCGGGCTCCGCCACGCCATGCCCGACGAGCTGCTGCAGCGCCTGCGCCGTTTCCACGACGATGCGTTCCCGCGCT
ACCGCCAGCGCTTCCAGGAC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSCTCQDSPASTGCRGSGSGGDLDHAVGIAPGFDADLPGHGPGSPAPAVPGPVASVNGVALHRADDAPDADTLRQRACTE
LLRQAAQRAGLLAADDAPADDGTTSEAATQAIEALLEQALAVPDPSEDACRRHYEAHTARYRDGERVHLRHVLYAVTPGV
DVQRLRERAEAELLQLRCAHDGGEAFARAARQWSNCPTGAEGGDLGWLARGDCAPEFAREVFGAQEVGVLPRLVHSRFGL
HVVEVVARDAGRQRGYGEVREAVALALRQQSWVNALRQYLQVLAGEAALQGVDLDGADTPLVQ

Sequences:

>Translated_303_residues
MSCTCQDSPASTGCRGSGSGGDLDHAVGIAPGFDADLPGHGPGSPAPAVPGPVASVNGVALHRADDAPDADTLRQRACTE
LLRQAAQRAGLLAADDAPADDGTTSEAATQAIEALLEQALAVPDPSEDACRRHYEAHTARYRDGERVHLRHVLYAVTPGV
DVQRLRERAEAELLQLRCAHDGGEAFARAARQWSNCPTGAEGGDLGWLARGDCAPEFAREVFGAQEVGVLPRLVHSRFGL
HVVEVVARDAGRQRGYGEVREAVALALRQQSWVNALRQYLQVLAGEAALQGVDLDGADTPLVQ
>Mature_302_residues
SCTCQDSPASTGCRGSGSGGDLDHAVGIAPGFDADLPGHGPGSPAPAVPGPVASVNGVALHRADDAPDADTLRQRACTEL
LRQAAQRAGLLAADDAPADDGTTSEAATQAIEALLEQALAVPDPSEDACRRHYEAHTARYRDGERVHLRHVLYAVTPGVD
VQRLRERAEAELLQLRCAHDGGEAFARAARQWSNCPTGAEGGDLGWLARGDCAPEFAREVFGAQEVGVLPRLVHSRFGLH
VVEVVARDAGRQRGYGEVREAVALALRQQSWVNALRQYLQVLAGEAALQGVDLDGADTPLVQ

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

None

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 31924; Mature: 31792

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCTCQDSPASTGCRGSGSGGDLDHAVGIAPGFDADLPGHGPGSPAPAVPGPVASVNGVA
CCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
LHRADDAPDADTLRQRACTELLRQAAQRAGLLAADDAPADDGTTSEAATQAIEALLEQAL
EECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHH
AVPDPSEDACRRHYEAHTARYRDGERVHLRHVLYAVTPGVDVQRLRERAEAELLQLRCAH
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
DGGEAFARAARQWSNCPTGAEGGDLGWLARGDCAPEFAREVFGAQEVGVLPRLVHSRFGL
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHH
HVVEVVARDAGRQRGYGEVREAVALALRQQSWVNALRQYLQVLAGEAALQGVDLDGADTP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LVQ
CCC
>Mature Secondary Structure 
SCTCQDSPASTGCRGSGSGGDLDHAVGIAPGFDADLPGHGPGSPAPAVPGPVASVNGVA
CCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
LHRADDAPDADTLRQRACTELLRQAAQRAGLLAADDAPADDGTTSEAATQAIEALLEQAL
EECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHH
AVPDPSEDACRRHYEAHTARYRDGERVHLRHVLYAVTPGVDVQRLRERAEAELLQLRCAH
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
DGGEAFARAARQWSNCPTGAEGGDLGWLARGDCAPEFAREVFGAQEVGVLPRLVHSRFGL
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHH
HVVEVVARDAGRQRGYGEVREAVALALRQQSWVNALRQYLQVLAGEAALQGVDLDGADTP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LVQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA