Click here to switch to the map view.

The map label for this gene is crp [C]

Identifier: 120609336

GI number: 120609336

Start: 686244

End: 686882

Strand: Reverse

Name: crp [C]

Synonym: Aave_0636

Alternate gene names: 120609336

Gene position: 686882-686244 (Counterclockwise)

Preceding gene: 120609337

Following gene: 120609335

Centisome position: 12.83

GC content: 69.01

Gene sequence:

>639_bases
ATGAAAGGCATCCTCGGCCTGCTGAAGGCCAAGTCCCGCGGCACCAAGTCCGGCGGCGAAGGCGCCAGCGATTCAGTCTT
CTTCACCACGGCCTTCGCTGGCCAGGGCGTGGACAGCTCCATGCTCGTGCCCTGGGAAGCGCGCGCCGTCGAAGTCGCGG
CCCAGCGCATGCCCGCCAGCCGCGGCGGCAAGCTGCTGCAGGCGCTGTGGTCCAAGGACCGCTACATGGCCCACCTCGAC
GCCTCCGCCGTCGAGCGCATGGAGCGCTTCTTCCACTTCGCTGCCGTGCCCGCAGACCGCGACGTGATCCGCCAGGACGA
ATACGGCAATTTCATGGTCGTGCTGCTCACCGGCACCATCGCCGTGGACCGCGTGCAGCCCTGGGGCGAGCACCTGCGGC
TCGCGGAAACCCGCCCGGGCGACATCCTGGGCGAGATGTCGCTGCTGGACAGCGGTATCCGCTTCTCCGCCTGCACCACG
CTGACCGATTGCGAGATCGCCGTACTCAGCGCCGAGGCCCTCGACGACATGATGGCCAAGGATCCCCAGTTGGCCGCGAG
CCTGGTCGCCCTGCTCGCGCGCAAGCTATCGCAGCGCCTGCGGGTCGTCAGCGCCCGCCTCAGCGACAGCCAGCGCTGA

Upstream 100 bases:

>100_bases
TTCCCGGGCTGACACCGGCCCGCTCGCACCGCACCGTTCACCCATCCCCCAACACACCGCGCGGCAGACATCACCCCGCC
GCGCGCACCGGAGCACCTCC

Downstream 100 bases:

>100_bases
CGCGGCGGCGCACCGACCGGAGCACTGAATGGAACGCGATCAGGCCAGCAAATTCATCAACGACCTGCTGAAGCTCATGG
TGGGGCGCGGCGGAAGCGAT

Product: cyclic nucleotide-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MKGILGLLKAKSRGTKSGGEGASDSVFFTTAFAGQGVDSSMLVPWEARAVEVAAQRMPASRGGKLLQALWSKDRYMAHLD
ASAVERMERFFHFAAVPADRDVIRQDEYGNFMVVLLTGTIAVDRVQPWGEHLRLAETRPGDILGEMSLLDSGIRFSACTT
LTDCEIAVLSAEALDDMMAKDPQLAASLVALLARKLSQRLRVVSARLSDSQR

Sequences:

>Translated_212_residues
MKGILGLLKAKSRGTKSGGEGASDSVFFTTAFAGQGVDSSMLVPWEARAVEVAAQRMPASRGGKLLQALWSKDRYMAHLD
ASAVERMERFFHFAAVPADRDVIRQDEYGNFMVVLLTGTIAVDRVQPWGEHLRLAETRPGDILGEMSLLDSGIRFSACTT
LTDCEIAVLSAEALDDMMAKDPQLAASLVALLARKLSQRLRVVSARLSDSQR
>Mature_212_residues
MKGILGLLKAKSRGTKSGGEGASDSVFFTTAFAGQGVDSSMLVPWEARAVEVAAQRMPASRGGKLLQALWSKDRYMAHLD
ASAVERMERFFHFAAVPADRDVIRQDEYGNFMVVLLTGTIAVDRVQPWGEHLRLAETRPGDILGEMSLLDSGIRFSACTT
LTDCEIAVLSAEALDDMMAKDPQLAASLVALLARKLSQRLRVVSARLSDSQR

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 23059; Mature: 23059

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGILGLLKAKSRGTKSGGEGASDSVFFTTAFAGQGVDSSMLVPWEARAVEVAAQRMPAS
CCCHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCEECCCHHHHHHHHHHHCCCC
RGGKLLQALWSKDRYMAHLDASAVERMERFFHFAAVPADRDVIRQDEYGNFMVVLLTGTI
CCHHHHHHHHCCCHHEECCCHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCEEEEEEECCC
AVDRVQPWGEHLRLAETRPGDILGEMSLLDSGIRFSACTTLTDCEIAVLSAEALDDMMAK
CEECCCCHHHHEEECCCCCCHHHHHHHHHHCCCCEEHCCCCCCCCEEEHHHHHHHHHHHC
DPQLAASLVALLARKLSQRLRVVSARLSDSQR
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKGILGLLKAKSRGTKSGGEGASDSVFFTTAFAGQGVDSSMLVPWEARAVEVAAQRMPAS
CCCHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCEECCCHHHHHHHHHHHCCCC
RGGKLLQALWSKDRYMAHLDASAVERMERFFHFAAVPADRDVIRQDEYGNFMVVLLTGTI
CCHHHHHHHHCCCHHEECCCHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCEEEEEEECCC
AVDRVQPWGEHLRLAETRPGDILGEMSLLDSGIRFSACTTLTDCEIAVLSAEALDDMMAK
CEECCCCHHHHEEECCCCCCHHHHHHHHHHCCCCEEHCCCCCCCCEEEHHHHHHHHHHHC
DPQLAASLVALLARKLSQRLRVVSARLSDSQR
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA