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The map label for this gene is tcp [H]

Identifier: 120609131

GI number: 120609131

Start: 462442

End: 464235

Strand: Reverse

Name: tcp [H]

Synonym: Aave_0428

Alternate gene names: 120609131

Gene position: 464235-462442 (Counterclockwise)

Preceding gene: 120609132

Following gene: 120609128

Centisome position: 8.67

GC content: 70.23

Gene sequence:

>1794_bases
ATGGCCGCCCGCTCCCTGACCGTTTCACAGCGCCTGCTTATCGCTTTCGGCCTGGTGATCGCCATCTTCGTCGCCGTGGC
CGCCACCGCGCTCGTCAGCAGCCGCAGCCTCGCGGAAGCCGAATCGTGGAATGAACACACCTACCAGGTGCTCGACCGCT
CCAACGCGCTGCTCAGGAGCATGATCAACATGGAAACCGGTGCGCGCGGCTTCCTGCTCAGTGGGGACGAAAAGCACCTG
GAGCCATGGAACGGCGGCGCCCGGGAATTCAACGAGGCGTTTGCCGACATCAAGGGCATGACGGCCGACAATCCCGTGCA
GCAGCAGCGCCTGGAGGCCATGAAGGCCCGGGAAACCGAATTCGCATCCGTGCTGTCCGGGCTCATCCAGGCGCGGCGTG
AAGTCACCGCGGGCAGCAGGACCCTGCAGGATTTACTGCCCCAGTTCGGCCAGGGCAAGGACAAGGCCGCCATGGACGCC
TTCCGGGCGCTGCAGAAGGAACTGGACCAGGCGGAATCGGGCCTGCTGGCCGAACGCAAGGCGGGAGCCGACCGGATGCG
CGGCATCAATACCGCCGTGATCCTGGCCGGGTCGGCGCTGGCCGTGGCACTGGCCGGCGCACTGGGCATCTGGGTCACGC
GCTCCATCACGCGCCAGCTCGGCGGCGAACCGGACTACGCGACCGGCATCGTGCGGCAGATCGCCCAGGGCAACCTGGCC
GTGGAAGTGGACACCCGCGCCGGAGACCGGTCCAGCCTGCTGGCCGGCATGAAGGACATGCGCGATCAGTTGGCCCGCGT
GGTCGGGCAGGTGCGGCAGAGCAGCGATTCCATCGCCACGGGCAGCACGCAGATCGCCACCGGCAACGCCGACCTGAGCC
AGCGCACCGAGGAACAGGCGTCCAACCTCCAGCAGACGGCCGCTTCCATGGAGCAGTTGACGGCCACCGTGAAGCACAAC
GGCGACACCGCCCGCCAGGCCACGCAACTGGCGAATTCCGCCAGCGAGGTCGCGGAGCGCGGCGGCACGGTGATGGGCCA
GGTGGTGAGCACCATGGGCGCCATCACCGATTCCAGCCGCAGGATTTCGGACATCATCGGCGTCATCGACGGCATCGCGT
TCCAGACCAACATCCTCGCGCTCAACGCGGCGGTGGAGGCGGCACGTGCCGGCGAGCAGGGCCGCGGCTTCGCGGTGGTG
GCGAGCGAGGTGCGCGGCCTCGCCCAGCGCAGCGCCGATGCCGCCAAGGAAATCAAGGCCCTCATCTCCACCAGCGTGGA
GAAGGTGGAGGCCGGCAGCCAGCAGGTCGAGGAGGCCGGCCGGACCATGTCCGACATCGTCACCCAGGTCAAGCGCGTGA
ACGACCTGATCAGCGAAATCAGCGCCGCCACCCAGGAACAGACGCAGGGCATCGGCCAGGTGAGCGAAGCGGTGAGCCAG
CTCGACCAGGTGACGCAGCAGAACGCCGCGCTGGTCGAGGAAAGCGCCGCCGCCGCGGACAGCCTCCGGGCACAGGCCGG
CAGGCTCGTGGATGCGGTGAGCCAGTTCCGCCTCCACCACGACCAGGGCCTGCCAGCCCCGGCACCGGTCCCCGTGGCCG
CACCGCGCGCCGTCGCGGCACCGGCGACGGCGGGCACCCTGCCTGCCGCCAGGCCGGCCCCGGCCCGGGTGCCTGCCCCG
CCGCGCGCACCGGCCCTGGCAGCCCGCCGACCCGCGCCCGTGCCCACGAAGGCCCCCGCGCCTTCGCTGGCCCTGGCGGG
CAGCTCGGGCGAGGACGACTGGACGAGCTTCTGA

Upstream 100 bases:

>100_bases
AATAACGCGAAATTCGTGAATTCCGAAAAATAATGAGCAAATATTTCAGATAGGATCCAAACTCAAAGAGCAAAGACGAC
TACTTTCCCTGGAGGTATCC

Downstream 100 bases:

>100_bases
CGGTCAGGGACCGCCCACGCGCTCCACGAGGCCGGCGCTGGCCTCGTTCAAACCGGCCACCTCCACGGAGCAGCCGTGGT
GCCGCAGCCGCTGCACCACC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 597; Mature: 596

Protein sequence:

>597_residues
MAARSLTVSQRLLIAFGLVIAIFVAVAATALVSSRSLAEAESWNEHTYQVLDRSNALLRSMINMETGARGFLLSGDEKHL
EPWNGGAREFNEAFADIKGMTADNPVQQQRLEAMKARETEFASVLSGLIQARREVTAGSRTLQDLLPQFGQGKDKAAMDA
FRALQKELDQAESGLLAERKAGADRMRGINTAVILAGSALAVALAGALGIWVTRSITRQLGGEPDYATGIVRQIAQGNLA
VEVDTRAGDRSSLLAGMKDMRDQLARVVGQVRQSSDSIATGSTQIATGNADLSQRTEEQASNLQQTAASMEQLTATVKHN
GDTARQATQLANSASEVAERGGTVMGQVVSTMGAITDSSRRISDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVV
ASEVRGLAQRSADAAKEIKALISTSVEKVEAGSQQVEEAGRTMSDIVTQVKRVNDLISEISAATQEQTQGIGQVSEAVSQ
LDQVTQQNAALVEESAAAADSLRAQAGRLVDAVSQFRLHHDQGLPAPAPVPVAAPRAVAAPATAGTLPAARPAPARVPAP
PRAPALAARRPAPVPTKAPAPSLALAGSSGEDDWTSF

Sequences:

>Translated_597_residues
MAARSLTVSQRLLIAFGLVIAIFVAVAATALVSSRSLAEAESWNEHTYQVLDRSNALLRSMINMETGARGFLLSGDEKHL
EPWNGGAREFNEAFADIKGMTADNPVQQQRLEAMKARETEFASVLSGLIQARREVTAGSRTLQDLLPQFGQGKDKAAMDA
FRALQKELDQAESGLLAERKAGADRMRGINTAVILAGSALAVALAGALGIWVTRSITRQLGGEPDYATGIVRQIAQGNLA
VEVDTRAGDRSSLLAGMKDMRDQLARVVGQVRQSSDSIATGSTQIATGNADLSQRTEEQASNLQQTAASMEQLTATVKHN
GDTARQATQLANSASEVAERGGTVMGQVVSTMGAITDSSRRISDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVV
ASEVRGLAQRSADAAKEIKALISTSVEKVEAGSQQVEEAGRTMSDIVTQVKRVNDLISEISAATQEQTQGIGQVSEAVSQ
LDQVTQQNAALVEESAAAADSLRAQAGRLVDAVSQFRLHHDQGLPAPAPVPVAAPRAVAAPATAGTLPAARPAPARVPAP
PRAPALAARRPAPVPTKAPAPSLALAGSSGEDDWTSF
>Mature_596_residues
AARSLTVSQRLLIAFGLVIAIFVAVAATALVSSRSLAEAESWNEHTYQVLDRSNALLRSMINMETGARGFLLSGDEKHLE
PWNGGAREFNEAFADIKGMTADNPVQQQRLEAMKARETEFASVLSGLIQARREVTAGSRTLQDLLPQFGQGKDKAAMDAF
RALQKELDQAESGLLAERKAGADRMRGINTAVILAGSALAVALAGALGIWVTRSITRQLGGEPDYATGIVRQIAQGNLAV
EVDTRAGDRSSLLAGMKDMRDQLARVVGQVRQSSDSIATGSTQIATGNADLSQRTEEQASNLQQTAASMEQLTATVKHNG
DTARQATQLANSASEVAERGGTVMGQVVSTMGAITDSSRRISDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVA
SEVRGLAQRSADAAKEIKALISTSVEKVEAGSQQVEEAGRTMSDIVTQVKRVNDLISEISAATQEQTQGIGQVSEAVSQL
DQVTQQNAALVEESAAAADSLRAQAGRLVDAVSQFRLHHDQGLPAPAPVPVAAPRAVAAPATAGTLPAARPAPARVPAPP
RAPALAARRPAPVPTKAPAPSLALAGSSGEDDWTSF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=334, Percent_Identity=56.8862275449102, Blast_Score=308, Evalue=6e-85,
Organism=Escherichia coli, GI2367378, Length=350, Percent_Identity=55.1428571428571, Blast_Score=298, Evalue=7e-82,
Organism=Escherichia coli, GI1787690, Length=324, Percent_Identity=54.6296296296296, Blast_Score=297, Evalue=1e-81,
Organism=Escherichia coli, GI1788194, Length=390, Percent_Identity=47.9487179487179, Blast_Score=291, Evalue=8e-80,
Organism=Escherichia coli, GI1789453, Length=248, Percent_Identity=51.6129032258064, Blast_Score=234, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 62437; Mature: 62306

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARSLTVSQRLLIAFGLVIAIFVAVAATALVSSRSLAEAESWNEHTYQVLDRSNALLRS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
MINMETGARGFLLSGDEKHLEPWNGGAREFNEAFADIKGMTADNPVQQQRLEAMKARETE
HHHHCCCCCCEEECCCHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
FASVLSGLIQARREVTAGSRTLQDLLPQFGQGKDKAAMDAFRALQKELDQAESGLLAERK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
AGADRMRGINTAVILAGSALAVALAGALGIWVTRSITRQLGGEPDYATGIVRQIAQGNLA
CCHHHHCCCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEE
VEVDTRAGDRSSLLAGMKDMRDQLARVVGQVRQSSDSIATGSTQIATGNADLSQRTEEQA
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHH
SNLQQTAASMEQLTATVKHNGDTARQATQLANSASEVAERGGTVMGQVVSTMGAITDSSR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHH
RISDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRGLAQRSADAAKEIKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LISTSVEKVEAGSQQVEEAGRTMSDIVTQVKRVNDLISEISAATQEQTQGIGQVSEAVSQ
HHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDQVTQQNAALVEESAAAADSLRAQAGRLVDAVSQFRLHHDQGLPAPAPVPVAAPRAVAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCC
PATAGTLPAARPAPARVPAPPRAPALAARRPAPVPTKAPAPSLALAGSSGEDDWTSF
CCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCC
>Mature Secondary Structure 
AARSLTVSQRLLIAFGLVIAIFVAVAATALVSSRSLAEAESWNEHTYQVLDRSNALLRS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
MINMETGARGFLLSGDEKHLEPWNGGAREFNEAFADIKGMTADNPVQQQRLEAMKARETE
HHHHCCCCCCEEECCCHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
FASVLSGLIQARREVTAGSRTLQDLLPQFGQGKDKAAMDAFRALQKELDQAESGLLAERK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
AGADRMRGINTAVILAGSALAVALAGALGIWVTRSITRQLGGEPDYATGIVRQIAQGNLA
CCHHHHCCCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEE
VEVDTRAGDRSSLLAGMKDMRDQLARVVGQVRQSSDSIATGSTQIATGNADLSQRTEEQA
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHH
SNLQQTAASMEQLTATVKHNGDTARQATQLANSASEVAERGGTVMGQVVSTMGAITDSSR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHH
RISDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRGLAQRSADAAKEIKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LISTSVEKVEAGSQQVEEAGRTMSDIVTQVKRVNDLISEISAATQEQTQGIGQVSEAVSQ
HHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDQVTQQNAALVEESAAAADSLRAQAGRLVDAVSQFRLHHDQGLPAPAPVPVAAPRAVAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCC
PATAGTLPAARPAPARVPAPPRAPALAARRPAPVPTKAPAPSLALAGSSGEDDWTSF
CCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]