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The map label for this gene is panE [C]

Identifier: 120608963

GI number: 120608963

Start: 290057

End: 291052

Strand: Reverse

Name: panE [C]

Synonym: Aave_0260

Alternate gene names: 120608963

Gene position: 291052-290057 (Counterclockwise)

Preceding gene: 120608964

Following gene: 120608962

Centisome position: 5.44

GC content: 71.18

Gene sequence:

>996_bases
ATGCAGGTTGCGATCTATGGTGCCGGCGCCATCGGCGGCTGGCTCGGCATGGGGCTGTCGCGCGGCGGTGCCGACGTGTC
TTTCGTGGCGCGGGGCCCCACGCTGGACGCCTTGCGCACCCAGGGCCTGCGCTGCATCCGGCCGGATGGCACCTGCGAGG
CCGTGCCCGTAGCGGCCCACGACGACCCGGCCGCGCTCGGTGCGCAGGACGTGGTCGTCCTGGCCGTCAAAGCCCCCGCC
CTGCCCGACGTGGCCGCGCGCATCGCCCCGCTGCTGGGCCCCAAAACCACCGTGCTCACGGCCATGAACGGCGTGCCGTG
GTGGTTCCTGGAGGGTTGCTCCGGCCCGGCGCATGGAAGGGAACTGGCTTCCGTGGACCCGGGCGGCTCGCTGGCACGCG
CCATTCCCGCCGAACGGGTCGTCGGCGGCGTGGTGCATGCCAGCTGCTCGGTCGATGGGCCCGGTGTCGTGCGGCAGCAT
TTCGGCAACCGGCTCATCCTGGGCGAGGCCGTCGGCGGCATCACCCCGCGCCTGGAGGCGCTCTCGGCGCTCATCGCGCG
TGGCGGCATCGAGGTGGAACAATCCCCGCGCATCCAGCAGGACATCTGGTTCAAGCTGTGGGGCAACATGACGATCAACC
CCATCAGCGCCCTGACCGGCGCCACCACCGACCGCATCCTCGACGACGACCTCGTGCGCGGCTTCGTCTCCGCCGTGATG
CTCGAAGCCAAGGCCATCGGCGAGTGCCTGGGCCTGCGCATCGACCAGCAGCCCGAGGACCGGCACGCGGTGACGCGCAA
GCTCGGCGCCTTCAAGACTTCCATGCTGCAGGACGTGGAGGCCGGCAAGCCGCTGGAGATCGACGCCCTGGTGGGCGCGG
TGCACGAGCTCGGCCGCGCCACCGGCGTGCCAACGCCCCATACCGATGCGCTGCTGGGCCTCGTGCGCCTGTTCGCATCC
AACCGCCTTTCCCTTCGCAACGAGACCCGACCATGA

Upstream 100 bases:

>100_bases
GCGCCCGCAGCACAATAGCCCCTCGGGCCCGGCGCATCCATTTCTGTGCGCCGGGCGGTCCCGCGCCCGCGGCGGCGCGA
TCCCGAGAAGGCAGGAAACG

Downstream 100 bases:

>100_bases
CCCCAGCCCTTACCCTCTACTACGCTCCCGGCACCTGCGCGCAGGCGGTGCGCATCGCCCTGTGCGAAGCCGGCGCGGAG
CACCGCCTGGTGCGCCTCGA

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MQVAIYGAGAIGGWLGMGLSRGGADVSFVARGPTLDALRTQGLRCIRPDGTCEAVPVAAHDDPAALGAQDVVVLAVKAPA
LPDVAARIAPLLGPKTTVLTAMNGVPWWFLEGCSGPAHGRELASVDPGGSLARAIPAERVVGGVVHASCSVDGPGVVRQH
FGNRLILGEAVGGITPRLEALSALIARGGIEVEQSPRIQQDIWFKLWGNMTINPISALTGATTDRILDDDLVRGFVSAVM
LEAKAIGECLGLRIDQQPEDRHAVTRKLGAFKTSMLQDVEAGKPLEIDALVGAVHELGRATGVPTPHTDALLGLVRLFAS
NRLSLRNETRP

Sequences:

>Translated_331_residues
MQVAIYGAGAIGGWLGMGLSRGGADVSFVARGPTLDALRTQGLRCIRPDGTCEAVPVAAHDDPAALGAQDVVVLAVKAPA
LPDVAARIAPLLGPKTTVLTAMNGVPWWFLEGCSGPAHGRELASVDPGGSLARAIPAERVVGGVVHASCSVDGPGVVRQH
FGNRLILGEAVGGITPRLEALSALIARGGIEVEQSPRIQQDIWFKLWGNMTINPISALTGATTDRILDDDLVRGFVSAVM
LEAKAIGECLGLRIDQQPEDRHAVTRKLGAFKTSMLQDVEAGKPLEIDALVGAVHELGRATGVPTPHTDALLGLVRLFAS
NRLSLRNETRP
>Mature_331_residues
MQVAIYGAGAIGGWLGMGLSRGGADVSFVARGPTLDALRTQGLRCIRPDGTCEAVPVAAHDDPAALGAQDVVVLAVKAPA
LPDVAARIAPLLGPKTTVLTAMNGVPWWFLEGCSGPAHGRELASVDPGGSLARAIPAERVVGGVVHASCSVDGPGVVRQH
FGNRLILGEAVGGITPRLEALSALIARGGIEVEQSPRIQQDIWFKLWGNMTINPISALTGATTDRILDDDLVRGFVSAVM
LEAKAIGECLGLRIDQQPEDRHAVTRKLGAFKTSMLQDVEAGKPLEIDALVGAVHELGRATGVPTPHTDALLGLVRLFAS
NRLSLRNETRP

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 34569; Mature: 34569

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVAIYGAGAIGGWLGMGLSRGGADVSFVARGPTLDALRTQGLRCIRPDGTCEAVPVAAH
CEEEEEECCHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHCCCEEECCCCCCCEEEEECC
DDPAALGAQDVVVLAVKAPALPDVAARIAPLLGPKTTVLTAMNGVPWWFLEGCSGPAHGR
CCCHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCHHEEECCCCCCEEEEECCCCCCCCC
ELASVDPGGSLARAIPAERVVGGVVHASCSVDGPGVVRQHFGNRLILGEAVGGITPRLEA
CCCCCCCCCHHHHHCCHHHHHHHHHEEECCCCCCHHHHHHCCCEEEEEHHHCCCCHHHHH
LSALIARGGIEVEQSPRIQQDIWFKLWGNMTINPISALTGATTDRILDDDLVRGFVSAVM
HHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEECHHHHHHCCCHHHHHHHHHHHHHHHHHH
LEAKAIGECLGLRIDQQPEDRHAVTRKLGAFKTSMLQDVEAGKPLEIDALVGAVHELGRA
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHH
TGVPTPHTDALLGLVRLFASNRLSLRNETRP
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MQVAIYGAGAIGGWLGMGLSRGGADVSFVARGPTLDALRTQGLRCIRPDGTCEAVPVAAH
CEEEEEECCHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHCCCEEECCCCCCCEEEEECC
DDPAALGAQDVVVLAVKAPALPDVAARIAPLLGPKTTVLTAMNGVPWWFLEGCSGPAHGR
CCCHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCHHEEECCCCCCEEEEECCCCCCCCC
ELASVDPGGSLARAIPAERVVGGVVHASCSVDGPGVVRQHFGNRLILGEAVGGITPRLEA
CCCCCCCCCHHHHHCCHHHHHHHHHEEECCCCCCHHHHHHCCCEEEEEHHHCCCCHHHHH
LSALIARGGIEVEQSPRIQQDIWFKLWGNMTINPISALTGATTDRILDDDLVRGFVSAVM
HHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEECHHHHHHCCCHHHHHHHHHHHHHHHHHH
LEAKAIGECLGLRIDQQPEDRHAVTRKLGAFKTSMLQDVEAGKPLEIDALVGAVHELGRA
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHH
TGVPTPHTDALLGLVRLFASNRLSLRNETRP
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]