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The map label for this gene is yliI [H]

Identifier: 120599122

GI number: 120599122

Start: 2670924

End: 2672108

Strand: Direct

Name: yliI [H]

Synonym: Sputw3181_2318

Alternate gene names: 120599122

Gene position: 2670924-2672108 (Clockwise)

Preceding gene: 120599121

Following gene: 120599123

Centisome position: 56.73

GC content: 47.59

Gene sequence:

>1185_bases
ATGTTTTTAGGGAGATTTATGAAACTGAGTACCTTGCCGCTAAGTACCTTAATCCTTGCTTTAGGTTTAGTGATAAACTC
ACCCATGATTTTTGCCCAATCCGTTGATACAAAAACCATTAGCATCAAAACAGAAACGGGTCATATTCAAATAAAAACCA
TCGCAGAAGGACTAGAAAATGTCTGGGGTATGGCATTTTTACCCGATGGCAGTATGCTCGTGACTGAACGTGCCGGAAGG
ATGCGCATTGTCAGTGCTGAAGGCAAAGTCGGTGAACCCTTAACGGGTTTGCCACCAATAGTTGCCAAAGGTCAAGGCGG
TTTGCTCGATGTGGTGCTTGCGCCCGATTTTGCCAGCAGCAAAAAAATCTATTTCAGTTATGCTGAACCCGGTGAAGGCA
ATTTAGCCTCTCTCAACAGTACCGCAGTCAGTTTTGCCACGCTCAATGGTAATAAACTTGAAAACCTTACCCGCGTTTTT
AGTCAGCAGCCCAAAATCAACAGCAACCATCATTTTGGTTCTCGTTTAGTGTGGGCGCCTGACGGCACACTGTTTATCAC
GCTTGGCGATCGATACAGCGAAAAAGAGCGCGCCCAAACATTGGATAATCACCTTGGCAAAGTCGTGCGTATTCATGCCG
ATGGTTCTGTGCCTAAGGATAATCCCTTCGTCAATACGGCCGGTGCCTTGCCGGAGATCTGGTCCTATGGCCACCGCAAT
ATGCAAGGTGCGGCAATACATCCCGTTAGCAGCACATTGTGGACGGGCGAGCATGGGCCGCAGGGCGGCGATGAGCTCAA
TATCGACCAAGCGGGTAAAAACTATGGCTGGCCCGTGATTACCTATGGGGAAAATTATGGCGGCGGCAAAATCGGCGAAG
GCACCCACAAGACGGGGATGGAGCAACCCGTCTACAAATGGGTACCCTCAATCGCCACGGCGGGCTTTATGTTTTACACA
GGTGATAAATTTCCACAGTGGCAAAATAATATTTTACTCGCCAGCCTAAAGGAAAAAACACTGGTGCGCTTAGTGCTTGA
TGGAGAAAAAATTATCAAAGAAGAACGGCTGCTGAAAACCGAATTAGGACAAAGATTACGCTCAGTCGTACAGGGGCCCG
ATGGACTGATTTATCTGGCGACCGACGAAGCTAAATCAACAATTTATCAGTTATCGCCGCAATAA

Upstream 100 bases:

>100_bases
AACGATGCCCCCAGTTTAACCGTTTTCGATTCAACTGTTGACAGGTTAATTGCCCTTAAATGACTGACTTGTTACTCTGA
ACCCTCACTGAGGATGAATA

Downstream 100 bases:

>100_bases
TATGAATGAATAGAATCAATGGATAGAATAGGTGCGCGATAAAAATCACTACAGACAAAAATCAGAAACATCTCTTTTTT
TCTGGCATAAATGACTAAGG

Product: glucose sorbosone dehydrogenase

Products: NA

Alternate protein names: Asd [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MFLGRFMKLSTLPLSTLILALGLVINSPMIFAQSVDTKTISIKTETGHIQIKTIAEGLENVWGMAFLPDGSMLVTERAGR
MRIVSAEGKVGEPLTGLPPIVAKGQGGLLDVVLAPDFASSKKIYFSYAEPGEGNLASLNSTAVSFATLNGNKLENLTRVF
SQQPKINSNHHFGSRLVWAPDGTLFITLGDRYSEKERAQTLDNHLGKVVRIHADGSVPKDNPFVNTAGALPEIWSYGHRN
MQGAAIHPVSSTLWTGEHGPQGGDELNIDQAGKNYGWPVITYGENYGGGKIGEGTHKTGMEQPVYKWVPSIATAGFMFYT
GDKFPQWQNNILLASLKEKTLVRLVLDGEKIIKEERLLKTELGQRLRSVVQGPDGLIYLATDEAKSTIYQLSPQ

Sequences:

>Translated_394_residues
MFLGRFMKLSTLPLSTLILALGLVINSPMIFAQSVDTKTISIKTETGHIQIKTIAEGLENVWGMAFLPDGSMLVTERAGR
MRIVSAEGKVGEPLTGLPPIVAKGQGGLLDVVLAPDFASSKKIYFSYAEPGEGNLASLNSTAVSFATLNGNKLENLTRVF
SQQPKINSNHHFGSRLVWAPDGTLFITLGDRYSEKERAQTLDNHLGKVVRIHADGSVPKDNPFVNTAGALPEIWSYGHRN
MQGAAIHPVSSTLWTGEHGPQGGDELNIDQAGKNYGWPVITYGENYGGGKIGEGTHKTGMEQPVYKWVPSIATAGFMFYT
GDKFPQWQNNILLASLKEKTLVRLVLDGEKIIKEERLLKTELGQRLRSVVQGPDGLIYLATDEAKSTIYQLSPQ
>Mature_394_residues
MFLGRFMKLSTLPLSTLILALGLVINSPMIFAQSVDTKTISIKTETGHIQIKTIAEGLENVWGMAFLPDGSMLVTERAGR
MRIVSAEGKVGEPLTGLPPIVAKGQGGLLDVVLAPDFASSKKIYFSYAEPGEGNLASLNSTAVSFATLNGNKLENLTRVF
SQQPKINSNHHFGSRLVWAPDGTLFITLGDRYSEKERAQTLDNHLGKVVRIHADGSVPKDNPFVNTAGALPEIWSYGHRN
MQGAAIHPVSSTLWTGEHGPQGGDELNIDQAGKNYGWPVITYGENYGGGKIGEGTHKTGMEQPVYKWVPSIATAGFMFYT
GDKFPQWQNNILLASLKEKTLVRLVLDGEKIIKEERLLKTELGQRLRSVVQGPDGLIYLATDEAKSTIYQLSPQ

Specific function: Aldose sugar dehydrogenase with broad substrate specificity. The physiological substrate is unknown. Can oxidize glucose to gluconolactone. Can also utilize D-arabinose, L- arabinose and 2-deoxy-glucose. Has higher activity towards oligomeric sugars, such

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PQQ oxidoreductase gdhB family [H]

Homologues:

Organism=Homo sapiens, GI124248546, Length=260, Percent_Identity=26.9230769230769, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI187936953, Length=258, Percent_Identity=25.1937984496124, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI187936955, Length=258, Percent_Identity=25.1937984496124, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI20143973, Length=239, Percent_Identity=25.9414225941423, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1787060, Length=351, Percent_Identity=46.1538461538462, Blast_Score=318, Evalue=4e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR011041 [H]

Pfam domain/function: PF07995 GSDH [H]

EC number: NA

Molecular weight: Translated: 42951; Mature: 42951

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLGRFMKLSTLPLSTLILALGLVINSPMIFAQSVDTKTISIKTETGHIQIKTIAEGLEN
CCCCCCHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCEEEEEEECCCEEEEEEHHHHHHH
VWGMAFLPDGSMLVTERAGRMRIVSAEGKVGEPLTGLPPIVAKGQGGLLDVVLAPDFASS
HCCEEECCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCEEECCCCCEEEEEECCCCCCC
KKIYFSYAEPGEGNLASLNSTAVSFATLNGNKLENLTRVFSQQPKINSNHHFGSRLVWAP
CEEEEEECCCCCCCEEECCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEECC
DGTLFITLGDRYSEKERAQTLDNHLGKVVRIHADGSVPKDNPFVNTAGALPEIWSYGHRN
CCEEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEECCCCCHHHHHCCCCC
MQGAAIHPVSSTLWTGEHGPQGGDELNIDQAGKNYGWPVITYGENYGGGKIGEGTHKTGM
CCCCEECCCCCCEECCCCCCCCCCCCCHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCC
EQPVYKWVPSIATAGFMFYTGDKFPQWQNNILLASLKEKTLVRLVLDGEKIIKEERLLKT
CCHHHHHHHHHHHCCEEEEECCCCCCCCCCEEEEEECCCEEEEEEECCHHHHHHHHHHHH
ELGQRLRSVVQGPDGLIYLATDEAKSTIYQLSPQ
HHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCC
>Mature Secondary Structure
MFLGRFMKLSTLPLSTLILALGLVINSPMIFAQSVDTKTISIKTETGHIQIKTIAEGLEN
CCCCCCHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCEEEEEEECCCEEEEEEHHHHHHH
VWGMAFLPDGSMLVTERAGRMRIVSAEGKVGEPLTGLPPIVAKGQGGLLDVVLAPDFASS
HCCEEECCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCEEECCCCCEEEEEECCCCCCC
KKIYFSYAEPGEGNLASLNSTAVSFATLNGNKLENLTRVFSQQPKINSNHHFGSRLVWAP
CEEEEEECCCCCCCEEECCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEECC
DGTLFITLGDRYSEKERAQTLDNHLGKVVRIHADGSVPKDNPFVNTAGALPEIWSYGHRN
CCEEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEECCCCCHHHHHCCCCC
MQGAAIHPVSSTLWTGEHGPQGGDELNIDQAGKNYGWPVITYGENYGGGKIGEGTHKTGM
CCCCEECCCCCCEECCCCCCCCCCCCCHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCC
EQPVYKWVPSIATAGFMFYTGDKFPQWQNNILLASLKEKTLVRLVLDGEKIIKEERLLKT
CCHHHHHHHHHHHCCEEEEECCCCCCCCCCEEEEEECCCEEEEEEECCHHHHHHHHHHHH
ELGQRLRSVVQGPDGLIYLATDEAKSTIYQLSPQ
HHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]