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The map label for this gene is mmgC [H]

Identifier: 120599110

GI number: 120599110

Start: 2658797

End: 2659966

Strand: Direct

Name: mmgC [H]

Synonym: Sputw3181_2306

Alternate gene names: 120599110

Gene position: 2658797-2659966 (Clockwise)

Preceding gene: 120599109

Following gene: 120599111

Centisome position: 56.47

GC content: 50.94

Gene sequence:

>1170_bases
ATGAACTCACTCTACACCAGTCTTAATTTTGGCCTAGGCGAAGATGTCGATATGCTGCGCGATGCAGTGCAGGATTTTGC
CGCGAATGAAATCGCACCGATTGCCGCGAAAGTGGATCACGACAATGCCTTTCCCAATGAACTTTGGCCTGTGCTTGGAG
GTATGGGACTGCTCGGCGTAACAGTACCCGAAGAGTTCGGCGGCGCGAACATGGGCTACCTTGCCCACGTCGTCGCAATG
GAAGAAATTTCCCGCGCCTCGGCCTCTATCGGCTTAAGTTACGGTGCCCACTCCAATCTGTGCGTAAACCAAATTAACCG
TAACGGTAATGCCGCACAAAAAGCCAAATACTTACCAAAGCTCGTCAGCGGTGAGCATATTGGCGCACTGGCTATGAGTG
AACCCAATGCGGGTTCTGATGTGGTTTCGATGAAACTGCACGCCCGCAAAGAAGGCGACCGTTATATTCTTAATGGCAAC
AAGATGTGGATCACCAACGGTCCCGATGCCAATACCTATGTTATTTATGCCAAAACCGACTTAACTAAGGGCGCCCACGG
CATCACCGCCTTTATCGTCGAGCGCGGTTTTAAAGGTTTCAGCCAAGCGCAAAAACTCGACAAACTCGGCATGCGCGGTT
CAAACACCTGTGAACTGGTGTTTGAAGAGGTAGAAGTGCCAGAGGAAAACATCCTTGGTGGCCTCAACAATGGCGTCAAA
GTGCTGATGAGTGGCTTAGATTACGAACGCGTAGTGCTCTCAGGCGGACCGTTGGGGATCATGAACGCCTGTATGGATAT
CGTTGTGCCTTATATCCACGAGCGTGAGCAATTTGGTAAATCAATCGGTGAATTCCAACTAGTACAAGGCAAGTTAGCCG
ACATGTACACCGGTATGAATGCCGCCAAATCCTATGTCTATAACGTAGCAAAATCCTGCGATCGCGGTGAAACTACCCGC
AAAGACGCCGCGGGCGCCATTCTCTACAGTGCGGAACTCGCCACAAAAATGGCACTGGATGCCATTCAATTGCTCGGCGG
TAATGGCTATGTCAACGAGTACGCGACAGGCCGCTTACTGCGCGATGCCAAACTCTATGAGATTGGCGCTGGCACCTCAG
AAATTCGCCGTATGCTGATTGGCCGCGAGCTCTTTAACGAATCGAAATAA

Upstream 100 bases:

>100_bases
GCGTGACAGGGATACATCACGCTAAGCAAGACAGTTTTAAAGACTCAAGCACCTAATAATCATAACAATATAAATTAGAA
CATCTGAAAGGACACAAGCA

Downstream 100 bases:

>100_bases
GCAGCCCAGGGCGAACGATGCATAACTCGGCTTAAGTCCTTCATGCTCCCTCGCCCAACTAAGCCAACGGATACTGAGTT
ACCGCTTTATAAGGACAATC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 3-methylbut-2-enoyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MNSLYTSLNFGLGEDVDMLRDAVQDFAANEIAPIAAKVDHDNAFPNELWPVLGGMGLLGVTVPEEFGGANMGYLAHVVAM
EEISRASASIGLSYGAHSNLCVNQINRNGNAAQKAKYLPKLVSGEHIGALAMSEPNAGSDVVSMKLHARKEGDRYILNGN
KMWITNGPDANTYVIYAKTDLTKGAHGITAFIVERGFKGFSQAQKLDKLGMRGSNTCELVFEEVEVPEENILGGLNNGVK
VLMSGLDYERVVLSGGPLGIMNACMDIVVPYIHEREQFGKSIGEFQLVQGKLADMYTGMNAAKSYVYNVAKSCDRGETTR
KDAAGAILYSAELATKMALDAIQLLGGNGYVNEYATGRLLRDAKLYEIGAGTSEIRRMLIGRELFNESK

Sequences:

>Translated_389_residues
MNSLYTSLNFGLGEDVDMLRDAVQDFAANEIAPIAAKVDHDNAFPNELWPVLGGMGLLGVTVPEEFGGANMGYLAHVVAM
EEISRASASIGLSYGAHSNLCVNQINRNGNAAQKAKYLPKLVSGEHIGALAMSEPNAGSDVVSMKLHARKEGDRYILNGN
KMWITNGPDANTYVIYAKTDLTKGAHGITAFIVERGFKGFSQAQKLDKLGMRGSNTCELVFEEVEVPEENILGGLNNGVK
VLMSGLDYERVVLSGGPLGIMNACMDIVVPYIHEREQFGKSIGEFQLVQGKLADMYTGMNAAKSYVYNVAKSCDRGETTR
KDAAGAILYSAELATKMALDAIQLLGGNGYVNEYATGRLLRDAKLYEIGAGTSEIRRMLIGRELFNESK
>Mature_389_residues
MNSLYTSLNFGLGEDVDMLRDAVQDFAANEIAPIAAKVDHDNAFPNELWPVLGGMGLLGVTVPEEFGGANMGYLAHVVAM
EEISRASASIGLSYGAHSNLCVNQINRNGNAAQKAKYLPKLVSGEHIGALAMSEPNAGSDVVSMKLHARKEGDRYILNGN
KMWITNGPDANTYVIYAKTDLTKGAHGITAFIVERGFKGFSQAQKLDKLGMRGSNTCELVFEEVEVPEENILGGLNNGVK
VLMSGLDYERVVLSGGPLGIMNACMDIVVPYIHEREQFGKSIGEFQLVQGKLADMYTGMNAAKSYVYNVAKSCDRGETTR
KDAAGAILYSAELATKMALDAIQLLGGNGYVNEYATGRLLRDAKLYEIGAGTSEIRRMLIGRELFNESK

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=64.6276595744681, Blast_Score=514, Evalue=1e-146,
Organism=Homo sapiens, GI226958414, Length=339, Percent_Identity=67.8466076696165, Blast_Score=493, Evalue=1e-139,
Organism=Homo sapiens, GI4557233, Length=386, Percent_Identity=40.4145077720207, Blast_Score=286, Evalue=2e-77,
Organism=Homo sapiens, GI4501859, Length=367, Percent_Identity=36.2397820163488, Blast_Score=257, Evalue=1e-68,
Organism=Homo sapiens, GI21361497, Length=380, Percent_Identity=37.6315789473684, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI4557231, Length=385, Percent_Identity=35.3246753246753, Blast_Score=229, Evalue=5e-60,
Organism=Homo sapiens, GI187960098, Length=385, Percent_Identity=35.3246753246753, Blast_Score=228, Evalue=5e-60,
Organism=Homo sapiens, GI4501857, Length=373, Percent_Identity=33.2439678284182, Blast_Score=224, Evalue=9e-59,
Organism=Homo sapiens, GI76496475, Length=353, Percent_Identity=35.9773371104816, Blast_Score=218, Evalue=6e-57,
Organism=Homo sapiens, GI4557235, Length=353, Percent_Identity=35.9773371104816, Blast_Score=218, Evalue=6e-57,
Organism=Homo sapiens, GI7656849, Length=383, Percent_Identity=31.331592689295, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI4503943, Length=375, Percent_Identity=29.0666666666667, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI7669494, Length=371, Percent_Identity=29.6495956873315, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI48976061, Length=284, Percent_Identity=25.3521126760563, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI211971008, Length=284, Percent_Identity=25.3521126760563, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI38505218, Length=292, Percent_Identity=22.6027397260274, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1786223, Length=383, Percent_Identity=27.6762402088773, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI87081958, Length=384, Percent_Identity=30.46875, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI87082384, Length=259, Percent_Identity=25.4826254826255, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081702, Length=341, Percent_Identity=24.633431085044, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538396, Length=380, Percent_Identity=63.1578947368421, Blast_Score=508, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI17506239, Length=378, Percent_Identity=33.8624338624339, Blast_Score=244, Evalue=6e-65,
Organism=Caenorhabditis elegans, GI17569725, Length=381, Percent_Identity=35.9580052493438, Blast_Score=237, Evalue=7e-63,
Organism=Caenorhabditis elegans, GI17508101, Length=371, Percent_Identity=33.6927223719677, Blast_Score=236, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17534899, Length=382, Percent_Identity=34.2931937172775, Blast_Score=228, Evalue=4e-60,
Organism=Caenorhabditis elegans, GI17570075, Length=386, Percent_Identity=32.3834196891192, Blast_Score=224, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI71990804, Length=276, Percent_Identity=39.4927536231884, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI71985184, Length=358, Percent_Identity=35.4748603351955, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17533517, Length=379, Percent_Identity=31.1345646437995, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17505929, Length=356, Percent_Identity=32.5842696629214, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=36.7965367965368, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17551932, Length=367, Percent_Identity=29.700272479564, Blast_Score=177, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI71985192, Length=318, Percent_Identity=34.5911949685535, Blast_Score=174, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI71982178, Length=274, Percent_Identity=32.8467153284672, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17534353, Length=375, Percent_Identity=29.0666666666667, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17531909, Length=246, Percent_Identity=31.3008130081301, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17531913, Length=183, Percent_Identity=28.4153005464481, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21355753, Length=384, Percent_Identity=61.1979166666667, Blast_Score=486, Evalue=1e-137,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=40.6914893617021, Blast_Score=293, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24646207, Length=376, Percent_Identity=36.968085106383, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24666513, Length=379, Percent_Identity=35.0923482849604, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI24660351, Length=387, Percent_Identity=35.6589147286822, Blast_Score=245, Evalue=4e-65,
Organism=Drosophila melanogaster, GI281363737, Length=359, Percent_Identity=33.4261838440111, Blast_Score=199, Evalue=3e-51,
Organism=Drosophila melanogaster, GI19920834, Length=388, Percent_Identity=28.8659793814433, Blast_Score=156, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.10

Molecular weight: Translated: 42011; Mature: 42011

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLYTSLNFGLGEDVDMLRDAVQDFAANEIAPIAAKVDHDNAFPNELWPVLGGMGLLGV
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHEEECCCCCCCCHHHHHHHCCCCEEEE
TVPEEFGGANMGYLAHVVAMEEISRASASIGLSYGAHSNLCVNQINRNGNAAQKAKYLPK
ECCHHHCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHCCCCCHHHHHHHHHH
LVSGEHIGALAMSEPNAGSDVVSMKLHARKEGDRYILNGNKMWITNGPDANTYVIYAKTD
HHCCCCCCEEEECCCCCCCCEEEEEEECCCCCCEEEECCCEEEEECCCCCCEEEEEEECC
LTKGAHGITAFIVERGFKGFSQAQKLDKLGMRGSNTCELVFEEVEVPEENILGGLNNGVK
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHCCCCCCCHH
VLMSGLDYERVVLSGGPLGIMNACMDIVVPYIHEREQFGKSIGEFQLVQGKLADMYTGMN
HHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHH
AAKSYVYNVAKSCDRGETTRKDAAGAILYSAELATKMALDAIQLLGGNGYVNEYATGRLL
HHHHHHHHHHHHCCCCCCCHHHHCCEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHCHHH
RDAKLYEIGAGTSEIRRMLIGRELFNESK
HCCEEEEECCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNSLYTSLNFGLGEDVDMLRDAVQDFAANEIAPIAAKVDHDNAFPNELWPVLGGMGLLGV
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHEEECCCCCCCCHHHHHHHCCCCEEEE
TVPEEFGGANMGYLAHVVAMEEISRASASIGLSYGAHSNLCVNQINRNGNAAQKAKYLPK
ECCHHHCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHCCCCCHHHHHHHHHH
LVSGEHIGALAMSEPNAGSDVVSMKLHARKEGDRYILNGNKMWITNGPDANTYVIYAKTD
HHCCCCCCEEEECCCCCCCCEEEEEEECCCCCCEEEECCCEEEEECCCCCCEEEEEEECC
LTKGAHGITAFIVERGFKGFSQAQKLDKLGMRGSNTCELVFEEVEVPEENILGGLNNGVK
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHCCCCCCCHH
VLMSGLDYERVVLSGGPLGIMNACMDIVVPYIHEREQFGKSIGEFQLVQGKLADMYTGMN
HHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHH
AAKSYVYNVAKSCDRGETTRKDAAGAILYSAELATKMALDAIQLLGGNGYVNEYATGRLL
HHHHHHHHHHHHCCCCCCCHHHHCCEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHCHHH
RDAKLYEIGAGTSEIRRMLIGRELFNESK
HCCEEEEECCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-methylbutanoyl-CoA; acceptor

Specific reaction: 3-methylbutanoyl-CoA + acceptor = 3-methylbut-2-enoyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]