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The map label for this gene is cirA [H]

Identifier: 120598991

GI number: 120598991

Start: 2517309

End: 2519294

Strand: Direct

Name: cirA [H]

Synonym: Sputw3181_2183

Alternate gene names: 120598991

Gene position: 2517309-2519294 (Clockwise)

Preceding gene: 120598990

Following gene: 120598992

Centisome position: 53.46

GC content: 44.61

Gene sequence:

>1986_bases
ATGTTTACTTTACAACGTTTATGTAAGAGCCGGATAAATTGTCCATCACTCCCCCGTTTTACCCCTTCGGTTTTATCCTG
TGCGGTTGCCATTGGATTATCGCTCTCAACAACCTTAGTTAATGCGGCAGAAACGACCTCAGTCAATCCAGACATGGAAC
GAATCGTGGTGACAGCAACTCAAACTAAGCACTCTGAACTTTCCGCCCCTGCATCGGTATCGGTGATTAATCGTGCAGAA
CTGGATGCGCTGGTCATCGACGACCTTGCTAGCGCGGTGCGTTATCTTCAAGGGGTAAATATTAGCGAAGGCACATCCTA
TGGCCGCAATGAGATCAGCCTACGTGGATTAGATTCTGATTACACACTGATTTTAATCAATGGCCGTCGAATCAACTCGC
GCGAAGCACTCACATCATCTTATGGCAACGATTTTGACTTGTCTTCTATTCCCATGTCAGCAATTGAGCGTATTGAAGTT
GTGCGTGGCCCTATGTCGTCTTTATATGGTTCAGAAGCCCTAGGTGGGGTCATCAACGTCATATTGCGTCAACCGACTGA
CGACTGGCAAACCAGTGTTGGTGTGCAATATGACACACCAACAAAAGGTGACGGCGGGGATACCACTAAATATAATTTTT
ATACCAGTGGCGCACTTATCAAAGACAAATTATTAGCAAATCTGATTGTGGATAGCAGCAAACGCGATGCGTGGCGCTCA
GATTTAAAACCTAAGCTAGATGCCCTTGAAGACCGAGATGAAATCAGTGCTATCGCCAATTTACAATGGCTTATTGATAG
CAACCAAGATTTACAGTTTGACCTCAGCTATGCCGATGATGAACGCGAATCCGATTGGAATAACTATGGTGCTATCCTCA
CAAACTACCAACAAGCGGAGCGGATAAGTTCAGGGTTAACCCATAATGGTCACTGGAATTGGGGCGATACTCGCCTACGC
TATTACTATGAAAATGTTGAAGTAACTGATAACTCAGCCCTAATTGCCGAGATTGGCAATATCACCCAAACCAACCATAA
TCTCGATGGGCAAAGTACCGTACTACTTGGCGATCATATGCTCACTGGTGGTGCTGAATATCGCTGGACTAAGCTTGAAA
ATAGCCGCAACGTCTTAGGTGACGGAGTGTTAGACGATAATCAATCGGCCCTTTATTTACAGGATGAATTTAACCTAGGC
GAACTCAATATCACCCTAGGTGGCCGTGTGGATCACCACGATGTTTACGGCACAGAATTCAGCCCTCGCCTGTATTTGGT
CTATAACCTCAGTTCTGAGTGGGTGATTAAAGGTGGTGGCGGTAAAGCGTTTAAAGCCCCCAATATGTCACAATCGCAAG
CTGATTATATTATTTCGTCTTGCCGTGGCTCTTGTACCCTTGCGGGTAACCCAGAATTAGAACCTGAAACCTCAGTCAAC
TATGAGTTGTCAACCCAATACCAAACTACGGATATTGGCGGCTCGATCACTTATTTCCATAACGATGTTGAAAATAAAAT
CATCACAGAAACTTGGAATAGGGTTCCCGGCGCGGTATTAACCTACCAAAACGTGAATGAAGCGAAGATAACAGGTTGGG
AATTACAAGCATGGTACGATTTGACCGATGATCTCAGCTTAAGTGGTAATTACAGCAAAACCGATGCAAAAGATAAACAA
AACGGCACGCCATTTACCCTAACGCCAGAGGATAGCTACAACATTAAACTACAGTGGCAAGCATTAGATGGCTTATCTAC
CTTTGTCGCCTACCACTATACTGGTGAGCAATATCTGCGAGCAAACGTCAAATCTGATGGTTATGGCTCATTAGACATTG
GAGCCAATTATCAAATAAACCCAATGTTTAGGCTTAAATTAGGTGTCACAAACCTCACGGATTCAGAACGAGATAATGCT
GCAACGGACCTTGACTACATTCAAAAGAGCCGTAGCGTATACGCAGGGATCACCGCGAGTTTCTAA

Upstream 100 bases:

>100_bases
TAAAACTTACAATAGATTTACATATAATGGTGAGCCATTCACTTGTTGCCTCCATTAAGAATAATTATCATTCGCCCAAT
TTTATCAAAGGAAGAATGAT

Downstream 100 bases:

>100_bases
ACCCTGTAAGCACTAATGGGTTTAAAACACTCGTAATTAGCCATAAATATAACGGTTGAAAATGCATTTTGCGTTTCACC
TGTTATATCCAATACATTAT

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MFTLQRLCKSRINCPSLPRFTPSVLSCAVAIGLSLSTTLVNAAETTSVNPDMERIVVTATQTKHSELSAPASVSVINRAE
LDALVIDDLASAVRYLQGVNISEGTSYGRNEISLRGLDSDYTLILINGRRINSREALTSSYGNDFDLSSIPMSAIERIEV
VRGPMSSLYGSEALGGVINVILRQPTDDWQTSVGVQYDTPTKGDGGDTTKYNFYTSGALIKDKLLANLIVDSSKRDAWRS
DLKPKLDALEDRDEISAIANLQWLIDSNQDLQFDLSYADDERESDWNNYGAILTNYQQAERISSGLTHNGHWNWGDTRLR
YYYENVEVTDNSALIAEIGNITQTNHNLDGQSTVLLGDHMLTGGAEYRWTKLENSRNVLGDGVLDDNQSALYLQDEFNLG
ELNITLGGRVDHHDVYGTEFSPRLYLVYNLSSEWVIKGGGGKAFKAPNMSQSQADYIISSCRGSCTLAGNPELEPETSVN
YELSTQYQTTDIGGSITYFHNDVENKIITETWNRVPGAVLTYQNVNEAKITGWELQAWYDLTDDLSLSGNYSKTDAKDKQ
NGTPFTLTPEDSYNIKLQWQALDGLSTFVAYHYTGEQYLRANVKSDGYGSLDIGANYQINPMFRLKLGVTNLTDSERDNA
ATDLDYIQKSRSVYAGITASF

Sequences:

>Translated_661_residues
MFTLQRLCKSRINCPSLPRFTPSVLSCAVAIGLSLSTTLVNAAETTSVNPDMERIVVTATQTKHSELSAPASVSVINRAE
LDALVIDDLASAVRYLQGVNISEGTSYGRNEISLRGLDSDYTLILINGRRINSREALTSSYGNDFDLSSIPMSAIERIEV
VRGPMSSLYGSEALGGVINVILRQPTDDWQTSVGVQYDTPTKGDGGDTTKYNFYTSGALIKDKLLANLIVDSSKRDAWRS
DLKPKLDALEDRDEISAIANLQWLIDSNQDLQFDLSYADDERESDWNNYGAILTNYQQAERISSGLTHNGHWNWGDTRLR
YYYENVEVTDNSALIAEIGNITQTNHNLDGQSTVLLGDHMLTGGAEYRWTKLENSRNVLGDGVLDDNQSALYLQDEFNLG
ELNITLGGRVDHHDVYGTEFSPRLYLVYNLSSEWVIKGGGGKAFKAPNMSQSQADYIISSCRGSCTLAGNPELEPETSVN
YELSTQYQTTDIGGSITYFHNDVENKIITETWNRVPGAVLTYQNVNEAKITGWELQAWYDLTDDLSLSGNYSKTDAKDKQ
NGTPFTLTPEDSYNIKLQWQALDGLSTFVAYHYTGEQYLRANVKSDGYGSLDIGANYQINPMFRLKLGVTNLTDSERDNA
ATDLDYIQKSRSVYAGITASF
>Mature_661_residues
MFTLQRLCKSRINCPSLPRFTPSVLSCAVAIGLSLSTTLVNAAETTSVNPDMERIVVTATQTKHSELSAPASVSVINRAE
LDALVIDDLASAVRYLQGVNISEGTSYGRNEISLRGLDSDYTLILINGRRINSREALTSSYGNDFDLSSIPMSAIERIEV
VRGPMSSLYGSEALGGVINVILRQPTDDWQTSVGVQYDTPTKGDGGDTTKYNFYTSGALIKDKLLANLIVDSSKRDAWRS
DLKPKLDALEDRDEISAIANLQWLIDSNQDLQFDLSYADDERESDWNNYGAILTNYQQAERISSGLTHNGHWNWGDTRLR
YYYENVEVTDNSALIAEIGNITQTNHNLDGQSTVLLGDHMLTGGAEYRWTKLENSRNVLGDGVLDDNQSALYLQDEFNLG
ELNITLGGRVDHHDVYGTEFSPRLYLVYNLSSEWVIKGGGGKAFKAPNMSQSQADYIISSCRGSCTLAGNPELEPETSVN
YELSTQYQTTDIGGSITYFHNDVENKIITETWNRVPGAVLTYQNVNEAKITGWELQAWYDLTDDLSLSGNYSKTDAKDKQ
NGTPFTLTPEDSYNIKLQWQALDGLSTFVAYHYTGEQYLRANVKSDGYGSLDIGANYQINPMFRLKLGVTNLTDSERDNA
ATDLDYIQKSRSVYAGITASF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=685, Percent_Identity=35.036496350365, Blast_Score=337, Evalue=1e-93,
Organism=Escherichia coli, GI1786798, Length=680, Percent_Identity=26.4705882352941, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1790405, Length=185, Percent_Identity=29.7297297297297, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 73259; Mature: 73259

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTLQRLCKSRINCPSLPRFTPSVLSCAVAIGLSLSTTLVNAAETTSVNPDMERIVVTAT
CCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHEEECHHCCCCCCCCEEEEEEEE
QTKHSELSAPASVSVINRAELDALVIDDLASAVRYLQGVNISEGTSYGRNEISLRGLDSD
CCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCC
YTLILINGRRINSREALTSSYGNDFDLSSIPMSAIERIEVVRGPMSSLYGSEALGGVINV
EEEEEEECCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHCCHHHHHHHHHH
ILRQPTDDWQTSVGVQYDTPTKGDGGDTTKYNFYTSGALIKDKLLANLIVDSSKRDAWRS
HHCCCCCHHHHCCCEEECCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHH
DLKPKLDALEDRDEISAIANLQWLIDSNQDLQFDLSYADDERESDWNNYGAILTNYQQAE
CCCCHHHHHCCHHHHHHHEEEEEEEECCCCEEEEEEECCCCCCCCCCCCCCEEECHHHHH
RISSGLTHNGHWNWGDTRLRYYYENVEVTDNSALIAEIGNITQTNHNLDGQSTVLLGDHM
HHHHCCCCCCCCCCCCCEEEEEEEEEEEECCCEEEEECCCCEECCCCCCCCEEEEEECEE
LTGGAEYRWTKLENSRNVLGDGVLDDNQSALYLQDEFNLGELNITLGGRVDHHDVYGTEF
ECCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCEECCCCCCCCCC
SPRLYLVYNLSSEWVIKGGGGKAFKAPNMSQSQADYIISSCRGSCTLAGNPELEPETSVN
CCEEEEEEECCCCEEEECCCCCEEECCCCCCHHHHHHHHHCCCCEEECCCCCCCCCCCCC
YELSTQYQTTDIGGSITYFHNDVENKIITETWNRVPGAVLTYQNVNEAKITGWELQAWYD
EEEECEEEEECCCCEEEEEECCCCCCHHHHHHHCCCCEEEEECCCCCCEEEEEEEEEEEC
LTDDLSLSGNYSKTDAKDKQNGTPFTLTPEDSYNIKLQWQALDGLSTFVAYHYTGEQYLR
CCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEEEECCCCEEEEEEEECCCEEEE
ANVKSDGYGSLDIGANYQINPMFRLKLGVTNLTDSERDNAATDLDYIQKSRSVYAGITAS
EECCCCCCCEEECCCCEEECEEEEEEEECCCCCCCCCCCCCHHHHHHHHCCCEEEEEEEC
F
C
>Mature Secondary Structure
MFTLQRLCKSRINCPSLPRFTPSVLSCAVAIGLSLSTTLVNAAETTSVNPDMERIVVTAT
CCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHEEECHHCCCCCCCCEEEEEEEE
QTKHSELSAPASVSVINRAELDALVIDDLASAVRYLQGVNISEGTSYGRNEISLRGLDSD
CCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCC
YTLILINGRRINSREALTSSYGNDFDLSSIPMSAIERIEVVRGPMSSLYGSEALGGVINV
EEEEEEECCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHCCHHHHHHHHHH
ILRQPTDDWQTSVGVQYDTPTKGDGGDTTKYNFYTSGALIKDKLLANLIVDSSKRDAWRS
HHCCCCCHHHHCCCEEECCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHH
DLKPKLDALEDRDEISAIANLQWLIDSNQDLQFDLSYADDERESDWNNYGAILTNYQQAE
CCCCHHHHHCCHHHHHHHEEEEEEEECCCCEEEEEEECCCCCCCCCCCCCCEEECHHHHH
RISSGLTHNGHWNWGDTRLRYYYENVEVTDNSALIAEIGNITQTNHNLDGQSTVLLGDHM
HHHHCCCCCCCCCCCCCEEEEEEEEEEEECCCEEEEECCCCEECCCCCCCCEEEEEECEE
LTGGAEYRWTKLENSRNVLGDGVLDDNQSALYLQDEFNLGELNITLGGRVDHHDVYGTEF
ECCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCEECCCCCCCCCC
SPRLYLVYNLSSEWVIKGGGGKAFKAPNMSQSQADYIISSCRGSCTLAGNPELEPETSVN
CCEEEEEEECCCCEEEECCCCCEEECCCCCCHHHHHHHHHCCCCEEECCCCCCCCCCCCC
YELSTQYQTTDIGGSITYFHNDVENKIITETWNRVPGAVLTYQNVNEAKITGWELQAWYD
EEEECEEEEECCCCEEEEEECCCCCCHHHHHHHCCCCEEEEECCCCCCEEEEEEEEEEEC
LTDDLSLSGNYSKTDAKDKQNGTPFTLTPEDSYNIKLQWQALDGLSTFVAYHYTGEQYLR
CCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEEEECCCCEEEEEEEECCCEEEE
ANVKSDGYGSLDIGANYQINPMFRLKLGVTNLTDSERDNAATDLDYIQKSRSVYAGITAS
EECCCCCCCEEECCCCEEECEEEEEEEECCCCCCCCCCCCCHHHHHHHHCCCEEEEEEEC
F
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]