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The map label for this gene is hlyB [H]

Identifier: 120598990

GI number: 120598990

Start: 2515611

End: 2517119

Strand: Direct

Name: hlyB [H]

Synonym: Sputw3181_2182

Alternate gene names: 120598990

Gene position: 2515611-2517119 (Clockwise)

Preceding gene: 120598985

Following gene: 120598991

Centisome position: 53.43

GC content: 44.86

Gene sequence:

>1509_bases
ATGAAAGAAGTAAAATTTCGTTGGATAGATCAATATCTTATCCACATGACCTTAAAAACTAAATTCGCTATTCTCGCCCT
TGTCCCCATGATTATGATTGTGGGATTAGCGGTTTTTCTTAATATCCAGTTTCAGCAAACCCTTATTGATACACATTTCA
AGACACTGCAAAACTCAGCACAACAAATTAATCAGATAACCGCCCAGCTCCATAGCAAATTACCGGACCAAGAACGCCAA
CGGCTACAAAACCAACTCAGTCACGGTAATGTAAACGTCATTGCCCTGAATAATGCTGATAATAAAGCACAATCCATCGC
CCGCAGTGGTGGCGGTATTGATGATAGTCAATCCCAAAGGGCGATAAGTGGCGTTAATGATCAAAATCAGATCACGATTA
TTTCCATTGATAATAGAGAGATAGATGCCCTGCTCGCCAAAGATAACCTGTTGGTGTATGGGCTGATGGCGGCACTGTTG
TTTGTGCTATTTTTGTTTAGCTATTACATTTCAACTTTTGTCGGTGGCGCGCTTTACACCACTGTCATGGCGTTAAAAAG
AGCGGCCTCAGGCGATTTAACCGGACGTTTAAACTTTTTCGAAGTGAAGGACGAATTCAGTATCTTAGCCATCAGCATTG
ATACCTTAGTCGAACGGCAACATACCTTAGTGAAGCAAATTGCGGAGTCGACCAATAAAATTCGCGAGGTGGTGTCATCG
TTTCGTAGCACCGCGCAGCAAGGTCAATCCCTCGCGGTAAATCAACGTCAACATCTCGATTCTTTAGCGACTGCAATGGA
AGAAATGACCGCCGCCGTAAAAGAAGTCGCCCGTAATGCCGAGCAATCCTCTGCCGAAACTCAAGAAGCTAATCAGCAAG
TGAGTGCGGGTGGTAAAGACATTGAAACCACAGTCAAAGCCATTGATCTGCTATCGGATGAAATTTCTGACGCCTCAAAT
GCCGTCAATATTCTCAATGATAATGCCAGCAAGATAGATGAAGTCGTTTCAAGCATTAATGCCATTTCCCAACAAACCAA
CCTACTCGCTCTCAACGCCGCGATTGAAGCAGCACGCGCGGGTGAACAAGGCCGCGGGTTTGCTGTCGTTGCTGATGAAG
TAAGAACCCTCGCAAGCCGCACTCAATCGGCTACCGTTGAAATTAAAACCATGATTGAATCGTTGCAATCGGGCATACGT
AACCTAACGCAAGTCATGTCGCGTACTGTGAACCAAGCCAATGAAGGCAAGCAACACGTACTGCAAACAGGTAAAGACTT
AGAGTTTATCGCCCACCATAGCAACAAAGTATTTGAAATGAGCGTACTTATTGCGACTTCCGCCGAAGAGCAATCGGCAG
TAGCCAATGAGATAGCCACCAATCTGATGGAAATTCGCAACCAGTCACACGATGTAGAACAATCGGCAAATCAATCCGTT
TCCGGTTGTGATGAACTGCAAGCAACAGCAGGACAACTCGACCAACTTATGGTGGGGTTAAAAGTCTAA

Upstream 100 bases:

>100_bases
GGATTGTTTAGGCATTAATACTTACAAAACAGAAAACTATAAAGTCTATGGCAAACTGACCGATACAGATTCGGTTCCAG
CCTAATTTAATGAGGCGCTA

Downstream 100 bases:

>100_bases
TGATTAAAGCAACAAGGGAGCCCATACTCCCTTGTTGCTTAATTATGCATCACTATTCCACTTATTATTAACTAATTCAT
TTTCATACGTAAAACTTACA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MKEVKFRWIDQYLIHMTLKTKFAILALVPMIMIVGLAVFLNIQFQQTLIDTHFKTLQNSAQQINQITAQLHSKLPDQERQ
RLQNQLSHGNVNVIALNNADNKAQSIARSGGGIDDSQSQRAISGVNDQNQITIISIDNREIDALLAKDNLLVYGLMAALL
FVLFLFSYYISTFVGGALYTTVMALKRAASGDLTGRLNFFEVKDEFSILAISIDTLVERQHTLVKQIAESTNKIREVVSS
FRSTAQQGQSLAVNQRQHLDSLATAMEEMTAAVKEVARNAEQSSAETQEANQQVSAGGKDIETTVKAIDLLSDEISDASN
AVNILNDNASKIDEVVSSINAISQQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQSATVEIKTMIESLQSGIR
NLTQVMSRTVNQANEGKQHVLQTGKDLEFIAHHSNKVFEMSVLIATSAEEQSAVANEIATNLMEIRNQSHDVEQSANQSV
SGCDELQATAGQLDQLMVGLKV

Sequences:

>Translated_502_residues
MKEVKFRWIDQYLIHMTLKTKFAILALVPMIMIVGLAVFLNIQFQQTLIDTHFKTLQNSAQQINQITAQLHSKLPDQERQ
RLQNQLSHGNVNVIALNNADNKAQSIARSGGGIDDSQSQRAISGVNDQNQITIISIDNREIDALLAKDNLLVYGLMAALL
FVLFLFSYYISTFVGGALYTTVMALKRAASGDLTGRLNFFEVKDEFSILAISIDTLVERQHTLVKQIAESTNKIREVVSS
FRSTAQQGQSLAVNQRQHLDSLATAMEEMTAAVKEVARNAEQSSAETQEANQQVSAGGKDIETTVKAIDLLSDEISDASN
AVNILNDNASKIDEVVSSINAISQQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQSATVEIKTMIESLQSGIR
NLTQVMSRTVNQANEGKQHVLQTGKDLEFIAHHSNKVFEMSVLIATSAEEQSAVANEIATNLMEIRNQSHDVEQSANQSV
SGCDELQATAGQLDQLMVGLKV
>Mature_502_residues
MKEVKFRWIDQYLIHMTLKTKFAILALVPMIMIVGLAVFLNIQFQQTLIDTHFKTLQNSAQQINQITAQLHSKLPDQERQ
RLQNQLSHGNVNVIALNNADNKAQSIARSGGGIDDSQSQRAISGVNDQNQITIISIDNREIDALLAKDNLLVYGLMAALL
FVLFLFSYYISTFVGGALYTTVMALKRAASGDLTGRLNFFEVKDEFSILAISIDTLVERQHTLVKQIAESTNKIREVVSS
FRSTAQQGQSLAVNQRQHLDSLATAMEEMTAAVKEVARNAEQSSAETQEANQQVSAGGKDIETTVKAIDLLSDEISDASN
AVNILNDNASKIDEVVSSINAISQQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQSATVEIKTMIESLQSGIR
NLTQVMSRTVNQANEGKQHVLQTGKDLEFIAHHSNKVFEMSVLIATSAEEQSAVANEIATNLMEIRNQSHDVEQSANQSV
SGCDELQATAGQLDQLMVGLKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=320, Percent_Identity=31.25, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI2367378, Length=319, Percent_Identity=30.4075235109718, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI1787690, Length=314, Percent_Identity=32.8025477707006, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1788194, Length=208, Percent_Identity=37.9807692307692, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789453, Length=187, Percent_Identity=34.2245989304813, Blast_Score=89, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 54873; Mature: 54873

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEVKFRWIDQYLIHMTLKTKFAILALVPMIMIVGLAVFLNIQFQQTLIDTHFKTLQNSA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQINQITAQLHSKLPDQERQRLQNQLSHGNVNVIALNNADNKAQSIARSGGGIDDSQSQR
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCCCCHHHH
AISGVNDQNQITIISIDNREIDALLAKDNLLVYGLMAALLFVLFLFSYYISTFVGGALYT
HHCCCCCCCCEEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVMALKRAASGDLTGRLNFFEVKDEFSILAISIDTLVERQHTLVKQIAESTNKIREVVSS
HHHHHHHHCCCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRSTAQQGQSLAVNQRQHLDSLATAMEEMTAAVKEVARNAEQSSAETQEANQQVSAGGKD
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
IETTVKAIDLLSDEISDASNAVNILNDNASKIDEVVSSINAISQQTNLLALNAAIEAARA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
GEQGRGFAVVADEVRTLASRTQSATVEIKTMIESLQSGIRNLTQVMSRTVNQANEGKQHV
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LQTGKDLEFIAHHSNKVFEMSVLIATSAEEQSAVANEIATNLMEIRNQSHDVEQSANQSV
HHCCCCHHHHHHCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
SGCDELQATAGQLDQLMVGLKV
CCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKEVKFRWIDQYLIHMTLKTKFAILALVPMIMIVGLAVFLNIQFQQTLIDTHFKTLQNSA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQINQITAQLHSKLPDQERQRLQNQLSHGNVNVIALNNADNKAQSIARSGGGIDDSQSQR
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCCCCHHHH
AISGVNDQNQITIISIDNREIDALLAKDNLLVYGLMAALLFVLFLFSYYISTFVGGALYT
HHCCCCCCCCEEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVMALKRAASGDLTGRLNFFEVKDEFSILAISIDTLVERQHTLVKQIAESTNKIREVVSS
HHHHHHHHCCCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRSTAQQGQSLAVNQRQHLDSLATAMEEMTAAVKEVARNAEQSSAETQEANQQVSAGGKD
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
IETTVKAIDLLSDEISDASNAVNILNDNASKIDEVVSSINAISQQTNLLALNAAIEAARA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
GEQGRGFAVVADEVRTLASRTQSATVEIKTMIESLQSGIRNLTQVMSRTVNQANEGKQHV
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LQTGKDLEFIAHHSNKVFEMSVLIATSAEEQSAVANEIATNLMEIRNQSHDVEQSANQSV
HHCCCCHHHHHHCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
SGCDELQATAGQLDQLMVGLKV
CCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]