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The map label for this gene is namA [H]

Identifier: 120598534

GI number: 120598534

Start: 1975837

End: 1976943

Strand: Direct

Name: namA [H]

Synonym: Sputw3181_1717

Alternate gene names: 120598534

Gene position: 1975837-1976943 (Clockwise)

Preceding gene: 120598531

Following gene: 120598537

Centisome position: 41.96

GC content: 46.34

Gene sequence:

>1107_bases
ATGGCTGATCTATTTTCATCATTTAAACTTAAAGATATCACCCTTAAAAACCGAATAGTTGTTGCTCCTATGTGCCAATA
TCAAGCCAAAGAAGGGCTTCCCAATGAGTGGCATCAAGTGCATTACACTAGCCTTGCTAGAGGTGGTGCAGGGCTTGTCA
TCGTTGAGGCAACCGCAGTGTCCCCTGAAGGACGTATTACTCCCCGTTGTCTTGGACTTTGGAACGATGAGCAAGCTGCT
GGTTTAGCTAAAGTCGCGAATGCAATTAAAAGTGCTGGTGCTGTAGCAGGGATCCAAATTGGTCATGCTGGACGTAAGGC
GAGTGCCAACATTCCTTGGGAAGGGGATGACCATATTGCCAATGGTGAGGCTGAAGCGTGGCAACCTATTTCACCGTCTC
CAGTGGCTTTTGGGGCTAACTTATCAAAAGTGCCCACAGAGATGACCGTTGAAGATATTGAGCGCGTTAAAGTCGATTTT
GTGACGGCAGCTAAGCGCGCCTTAGCCGCTGGTTTTGAATGGTTAGAATTGCATTTTGCCCATGGTTACCTAGCACAAAG
CTTTTTTTCAACCTATGCCAACCAGCGTTCAGATCAATATGGTGGTAGTGCTGAAGGGCGTGGACGATTCCTATTAGAAA
CGATTAAAGCCGTAAGAGAGATTTGGCCACAACATCTGCCCTTAACGGCACGTTTCGGAGTGATTGAATTTGATGACAAA
GATGAGCAAACCTTATCAGAATCAATTGAATTGGTTAAACAGTTCAAGCAGATAGGTTTGGATATGCTAAATGTGAGCAT
TTGTTTTTCGACCCCAACAGCCAATATTCCATGGCGTCCTGCATTGTTAGCGCCTATTGCAGCGCGGGTGCGTAAGGAGG
TGGGATTCCCTGTTGCGACTTCCTGGGGGATGGATGATCCACATCAAGCCAATGCGGCAATTGAAAATGAGCAAATGGAT
TTAGTGATGATAGGCAAGGCGTTTTTAGCTAATCCGCATTGGCCTTATCAAGCGGCACAAATATTAAAGATAGACCGTCC
ATCTTGGGTGCTACCATCCTCCTATGCCCATTGGTTGGAGCGCTATTCAACGGTTAAGGTTGGCTGA

Upstream 100 bases:

>100_bases
TCAAACCTATAATCTAAGAGTGCTTTTAATTATGGCATGATGGGATTAGGCTGTCGTCATTGATTCTGAACATTCGACGG
ATACAGGAAATTAAATACCC

Downstream 100 bases:

>100_bases
GCGACTGGTTATTTCAATCTTGATGCTTTATCACTAAAAAGCCCTAAGCCATTGCTGGATTAGGGCTTTTTATTTATTGT
TTAATTAATGATTATAGAGA

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MADLFSSFKLKDITLKNRIVVAPMCQYQAKEGLPNEWHQVHYTSLARGGAGLVIVEATAVSPEGRITPRCLGLWNDEQAA
GLAKVANAIKSAGAVAGIQIGHAGRKASANIPWEGDDHIANGEAEAWQPISPSPVAFGANLSKVPTEMTVEDIERVKVDF
VTAAKRALAAGFEWLELHFAHGYLAQSFFSTYANQRSDQYGGSAEGRGRFLLETIKAVREIWPQHLPLTARFGVIEFDDK
DEQTLSESIELVKQFKQIGLDMLNVSICFSTPTANIPWRPALLAPIAARVRKEVGFPVATSWGMDDPHQANAAIENEQMD
LVMIGKAFLANPHWPYQAAQILKIDRPSWVLPSSYAHWLERYSTVKVG

Sequences:

>Translated_368_residues
MADLFSSFKLKDITLKNRIVVAPMCQYQAKEGLPNEWHQVHYTSLARGGAGLVIVEATAVSPEGRITPRCLGLWNDEQAA
GLAKVANAIKSAGAVAGIQIGHAGRKASANIPWEGDDHIANGEAEAWQPISPSPVAFGANLSKVPTEMTVEDIERVKVDF
VTAAKRALAAGFEWLELHFAHGYLAQSFFSTYANQRSDQYGGSAEGRGRFLLETIKAVREIWPQHLPLTARFGVIEFDDK
DEQTLSESIELVKQFKQIGLDMLNVSICFSTPTANIPWRPALLAPIAARVRKEVGFPVATSWGMDDPHQANAAIENEQMD
LVMIGKAFLANPHWPYQAAQILKIDRPSWVLPSSYAHWLERYSTVKVG
>Mature_367_residues
ADLFSSFKLKDITLKNRIVVAPMCQYQAKEGLPNEWHQVHYTSLARGGAGLVIVEATAVSPEGRITPRCLGLWNDEQAAG
LAKVANAIKSAGAVAGIQIGHAGRKASANIPWEGDDHIANGEAEAWQPISPSPVAFGANLSKVPTEMTVEDIERVKVDFV
TAAKRALAAGFEWLELHFAHGYLAQSFFSTYANQRSDQYGGSAEGRGRFLLETIKAVREIWPQHLPLTARFGVIEFDDKD
EQTLSESIELVKQFKQIGLDMLNVSICFSTPTANIPWRPALLAPIAARVRKEVGFPVATSWGMDDPHQANAAIENEQMDL
VMIGKAFLANPHWPYQAAQILKIDRPSWVLPSSYAHWLERYSTVKVG

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=348, Percent_Identity=27.2988505747126, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789463, Length=340, Percent_Identity=26.4705882352941, Blast_Score=112, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17565138, Length=343, Percent_Identity=25.9475218658892, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17559802, Length=350, Percent_Identity=26.5714285714286, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17540738, Length=363, Percent_Identity=25.6198347107438, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI72001454, Length=349, Percent_Identity=26.3610315186246, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17566914, Length=222, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17564188, Length=270, Percent_Identity=27.4074074074074, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17559804, Length=269, Percent_Identity=26.3940520446097, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6325086, Length=231, Percent_Identity=29.4372294372294, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6321973, Length=239, Percent_Identity=29.2887029288703, Blast_Score=93, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 40472; Mature: 40341

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLFSSFKLKDITLKNRIVVAPMCQYQAKEGLPNEWHQVHYTSLARGGAGLVIVEATAV
CCCCHHCCCEEEEEECCEEEEECHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEEEE
SPEGRITPRCLGLWNDEQAAGLAKVANAIKSAGAVAGIQIGHAGRKASANIPWEGDDHIA
CCCCCCCHHEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCC
NGEAEAWQPISPSPVAFGANLSKVPTEMTVEDIERVKVDFVTAAKRALAAGFEWLELHFA
CCCCCCCCCCCCCCEEECCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
HGYLAQSFFSTYANQRSDQYGGSAEGRGRFLLETIKAVREIWPQHLPLTARFGVIEFDDK
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCEEEECCC
DEQTLSESIELVKQFKQIGLDMLNVSICFSTPTANIPWRPALLAPIAARVRKEVGFPVAT
HHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEE
SWGMDDPHQANAAIENEQMDLVMIGKAFLANPHWPYQAAQILKIDRPSWVLPSSYAHWLE
CCCCCCCCCCCCEECCCCCCEEEECHHHHCCCCCCCCHHHEEEECCCCCCCCHHHHHHHH
RYSTVKVG
HHHCCCCC
>Mature Secondary Structure 
ADLFSSFKLKDITLKNRIVVAPMCQYQAKEGLPNEWHQVHYTSLARGGAGLVIVEATAV
CCCHHCCCEEEEEECCEEEEECHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEEEE
SPEGRITPRCLGLWNDEQAAGLAKVANAIKSAGAVAGIQIGHAGRKASANIPWEGDDHIA
CCCCCCCHHEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCC
NGEAEAWQPISPSPVAFGANLSKVPTEMTVEDIERVKVDFVTAAKRALAAGFEWLELHFA
CCCCCCCCCCCCCCEEECCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
HGYLAQSFFSTYANQRSDQYGGSAEGRGRFLLETIKAVREIWPQHLPLTARFGVIEFDDK
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCEEEECCC
DEQTLSESIELVKQFKQIGLDMLNVSICFSTPTANIPWRPALLAPIAARVRKEVGFPVAT
HHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEE
SWGMDDPHQANAAIENEQMDLVMIGKAFLANPHWPYQAAQILKIDRPSWVLPSSYAHWLE
CCCCCCCCCCCCEECCCCCCEEEECHHHHCCCCCCCCHHHEEEECCCCCCCCHHHHHHHH
RYSTVKVG
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA