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The map label for this gene is asd [H]

Identifier: 120598383

GI number: 120598383

Start: 1782540

End: 1783556

Strand: Direct

Name: asd [H]

Synonym: Sputw3181_1565

Alternate gene names: 120598383

Gene position: 1782540-1783556 (Clockwise)

Preceding gene: 120598382

Following gene: 120598384

Centisome position: 37.86

GC content: 44.74

Gene sequence:

>1017_bases
ATGTCACAGGAATTTAATGTTGTCGTTTTAGGTGCATCGGGCGCAGTGGGTCAAACTATGATTGAGATCCTCGAAGAGCG
TAACTTCCCGGTTGCCAATTTGTACCCTTTAGCCAGTAGCCGCAGCGCCGGTGAAACGGTCAGCTTTCATGGCAAACAAA
TTACCATTCTGGACGTAGAAACCTTCGATTGGAGCCAAGCCCAAATCGGTTTCTTCTCTGCCGGTGGTGATGTTTCTGCC
ATATGGGCACCGATTGCCGCTGAAGCAGGTTGTGTTGTGATTGATAACACCTCTCACTTTAGATACGACATCGATATTCC
TTTGGTTGTACCTGAAGTGAATCCGCATGCTATCGCGGATTTTCGCAATCGCAATATCATTGCTAACCCAAATTGTTCCA
CGATTCAAATGCTGGTGGCACTTAAGCCTATTTATGATGCCTATGGGATCAGCCGTATTAATGTCGCGACTTATCAGTCA
GTATCGGGTACAGGTAAAAAAGCCATTGAAGAATTGGCGCATCAGTGCACTAAATTACTGCAAGGTTTACCCGCTGACGC
TGAAGTCTATCCGAAGCAAATTGCTTTTAACGTATTGCCACAAATCGATAAATTTATGGATAACGGCTATACCAAAGAAG
AAATGAAAATGGTCTGGGAAACCCAGAAGATTTTCGGTGACGATGAGATTTTAGTGAATGCGACAGCTGTACGTGTGCCT
GTGTTTTATGGTCACTCGGAAGCCATTAATATCGAAACTCGTCAGCCTGTTGATGCCGAAGACGTTAAAGCTTTACTGCG
TAATGCCGAAGGAGTGGTATTGTTTGAATCCGATGAGGATTATCCAACAGCAGTGACCGATGCCGCAGGAACCGATCCGG
TTTATGTGGGTCGCATTCGTAAGGATATTTCTCATTCTCACGGCCTTAATCTGTGGGTCGTGTCTGACAATATTCGTAAA
GGTGCAGCCTTAAATAGTGTGCAAATTGCCGAGATCTTAGTGAGAGATTATTACTAA

Upstream 100 bases:

>100_bases
GACATCGACGTGAATTTAGTGCATTGGCGCTGGCTTATGACCGTCAACTTGAGGTAGATTGGTTATCCAATTTAGGGTTT
TCAGGAGTCGGTCAGTAGCT

Downstream 100 bases:

>100_bases
GTATTAACGTGCATTTGATGCCATTGAAAAAGCCTGCTGTCAGCGGGCTTTTTTTGTTTTACAATTGTGAACAGTAGCAG
GGCGGGGATTTCTAGTTTAT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSQEFNVVVLGASGAVGQTMIEILEERNFPVANLYPLASSRSAGETVSFHGKQITILDVETFDWSQAQIGFFSAGGDVSA
IWAPIAAEAGCVVIDNTSHFRYDIDIPLVVPEVNPHAIADFRNRNIIANPNCSTIQMLVALKPIYDAYGISRINVATYQS
VSGTGKKAIEELAHQCTKLLQGLPADAEVYPKQIAFNVLPQIDKFMDNGYTKEEMKMVWETQKIFGDDEILVNATAVRVP
VFYGHSEAINIETRQPVDAEDVKALLRNAEGVVLFESDEDYPTAVTDAAGTDPVYVGRIRKDISHSHGLNLWVVSDNIRK
GAALNSVQIAEILVRDYY

Sequences:

>Translated_338_residues
MSQEFNVVVLGASGAVGQTMIEILEERNFPVANLYPLASSRSAGETVSFHGKQITILDVETFDWSQAQIGFFSAGGDVSA
IWAPIAAEAGCVVIDNTSHFRYDIDIPLVVPEVNPHAIADFRNRNIIANPNCSTIQMLVALKPIYDAYGISRINVATYQS
VSGTGKKAIEELAHQCTKLLQGLPADAEVYPKQIAFNVLPQIDKFMDNGYTKEEMKMVWETQKIFGDDEILVNATAVRVP
VFYGHSEAINIETRQPVDAEDVKALLRNAEGVVLFESDEDYPTAVTDAAGTDPVYVGRIRKDISHSHGLNLWVVSDNIRK
GAALNSVQIAEILVRDYY
>Mature_337_residues
SQEFNVVVLGASGAVGQTMIEILEERNFPVANLYPLASSRSAGETVSFHGKQITILDVETFDWSQAQIGFFSAGGDVSAI
WAPIAAEAGCVVIDNTSHFRYDIDIPLVVPEVNPHAIADFRNRNIIANPNCSTIQMLVALKPIYDAYGISRINVATYQSV
SGTGKKAIEELAHQCTKLLQGLPADAEVYPKQIAFNVLPQIDKFMDNGYTKEEMKMVWETQKIFGDDEILVNATAVRVPV
FYGHSEAINIETRQPVDAEDVKALLRNAEGVVLFESDEDYPTAVTDAAGTDPVYVGRIRKDISHSHGLNLWVVSDNIRKG
AALNSVQIAEILVRDYY

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=338, Percent_Identity=45.8579881656805, Blast_Score=313, Evalue=7e-87,
Organism=Escherichia coli, GI1789841, Length=355, Percent_Identity=28.7323943661972, Blast_Score=95, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6320362, Length=383, Percent_Identity=29.7650130548303, Blast_Score=95, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37138; Mature: 37007

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQEFNVVVLGASGAVGQTMIEILEERNFPVANLYPLASSRSAGETVSFHGKQITILDVE
CCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEECCCEEEEEEEE
TFDWSQAQIGFFSAGGDVSAIWAPIAAEAGCVVIDNTSHFRYDIDIPLVVPEVNPHAIAD
CCCCCCCEEEEEECCCCCEEEEEHHHCCCCEEEEECCCCEEEEECCEEEEECCCCCHHHH
FRNRNIIANPNCSTIQMLVALKPIYDAYGISRINVATYQSVSGTGKKAIEELAHQCTKLL
HCCCCEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHH
QGLPADAEVYPKQIAFNVLPQIDKFMDNGYTKEEMKMVWETQKIFGDDEILVNATAVRVP
HCCCCCHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEE
VFYGHSEAINIETRQPVDAEDVKALLRNAEGVVLFESDEDYPTAVTDAAGTDPVYVGRIR
EEECCCCEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCEECCCCCCCCEEEHHHH
KDISHSHGLNLWVVSDNIRKGAALNSVQIAEILVRDYY
HHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SQEFNVVVLGASGAVGQTMIEILEERNFPVANLYPLASSRSAGETVSFHGKQITILDVE
CCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEECCCEEEEEEEE
TFDWSQAQIGFFSAGGDVSAIWAPIAAEAGCVVIDNTSHFRYDIDIPLVVPEVNPHAIAD
CCCCCCCEEEEEECCCCCEEEEEHHHCCCCEEEEECCCCEEEEECCEEEEECCCCCHHHH
FRNRNIIANPNCSTIQMLVALKPIYDAYGISRINVATYQSVSGTGKKAIEELAHQCTKLL
HCCCCEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHH
QGLPADAEVYPKQIAFNVLPQIDKFMDNGYTKEEMKMVWETQKIFGDDEILVNATAVRVP
HCCCCCHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEE
VFYGHSEAINIETRQPVDAEDVKALLRNAEGVVLFESDEDYPTAVTDAAGTDPVYVGRIR
EEECCCCEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCEECCCCCCCCEEEHHHH
KDISHSHGLNLWVVSDNIRKGAALNSVQIAEILVRDYY
HHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163523 [H]