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The map label for this gene is etfA [H]

Identifier: 120598316

GI number: 120598316

Start: 1691533

End: 1692459

Strand: Direct

Name: etfA [H]

Synonym: Sputw3181_1498

Alternate gene names: 120598316

Gene position: 1691533-1692459 (Clockwise)

Preceding gene: 120598315

Following gene: 120598317

Centisome position: 35.93

GC content: 49.08

Gene sequence:

>927_bases
ATGGCCATTTTAGTATTAGCTGAACATGATAATGCGGCGTTGAAACTCGATACGGCTAAGGTTGTTAACGCGGCACGGGC
AATAGGTGATGAAGTCCATGTACTTGTCGTGGGCCATCAATGTGGTGCGGTAGTGCAAGCTGCACAGGCGCTACAAGGTG
TAAGCCAAGTGTTAGTGGCCGATGCCAGCGCCTATGAAGCGCATTTAGCGGAAAATGTAGCCAAGCTGCTAGTGGATTTA
TCCCCTCAATATGGTCATATTCTGTCTGCCGCATCGAGTATGGGCAAAGACACTCTGCCACGAGTTGCAGCGCTTTTAGA
TGTTGCACAAATTTCTGAAGTGATTGCTGTGGTGAGTGCTGATACGTTTGTGCGCCCTGTTTATGCAGGTAGTGCTTTAG
CTACAGTACAGAGCCATGATGCGATTAAAGTCATGACAGTCCGCGCTAGTGCATTTGATGCTGTGCCAGAAGGGAATAGC
GCTGTTGTGACTCCGCTCGATAAAGTATTTGAAGCAAAGACGCAATTTGTTTCTCAATCACTTACGGTGTCAGCGCGTCC
CGAACTAGGTAATGCTGGCATTATTGTGTCAGGTGGTCGTGGCATGGGCAGTGGTGAAAACTTCGGCATGCTAGAGCAAT
TAGCGGACAAACTGGGCGCCGCAGTGGGAGCCTCGCGAGCAGCGGTTGATGCGGGTTTTGTGCCTAATGATTTGCAAGTG
GGTCAGACGGGTAAAATTGTCGCTCCCAATCTCTATATTGCTGTCGGTATTTCGGGGGCAATCCAGCATTTAGCGGGGAT
GAAAGACGCTAAAGTCATCGTTGCTATCAATAAAGATCCTGAAGCACCGATATTCCAAGTCGCCGATTATGGCCTCGAAG
CGGATTTGTTTGAGGCTGTTCCGGAGTTGATTGCAAGTCTAAGTTGA

Upstream 100 bases:

>100_bases
AGTAAAGGTCACGCCTCCTGCAGAACGCAAAGCGGGCATTATGGTAGCGTCGGTAGCTGAGCTAGTTGAAAAGTTAAAAA
ATGAAGCGAAGGTGATCTAA

Downstream 100 bases:

>100_bases
TTTTATCTGTGACATCGGTCACAGTAAGCGGCTTTGCGGTAGCATCTGCTTAGCCGCTTATGTTTTTATGTGCCTCACGC
CCGTGAATGGGCGTTCTTAG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MAILVLAEHDNAALKLDTAKVVNAARAIGDEVHVLVVGHQCGAVVQAAQALQGVSQVLVADASAYEAHLAENVAKLLVDL
SPQYGHILSAASSMGKDTLPRVAALLDVAQISEVIAVVSADTFVRPVYAGSALATVQSHDAIKVMTVRASAFDAVPEGNS
AVVTPLDKVFEAKTQFVSQSLTVSARPELGNAGIIVSGGRGMGSGENFGMLEQLADKLGAAVGASRAAVDAGFVPNDLQV
GQTGKIVAPNLYIAVGISGAIQHLAGMKDAKVIVAINKDPEAPIFQVADYGLEADLFEAVPELIASLS

Sequences:

>Translated_308_residues
MAILVLAEHDNAALKLDTAKVVNAARAIGDEVHVLVVGHQCGAVVQAAQALQGVSQVLVADASAYEAHLAENVAKLLVDL
SPQYGHILSAASSMGKDTLPRVAALLDVAQISEVIAVVSADTFVRPVYAGSALATVQSHDAIKVMTVRASAFDAVPEGNS
AVVTPLDKVFEAKTQFVSQSLTVSARPELGNAGIIVSGGRGMGSGENFGMLEQLADKLGAAVGASRAAVDAGFVPNDLQV
GQTGKIVAPNLYIAVGISGAIQHLAGMKDAKVIVAINKDPEAPIFQVADYGLEADLFEAVPELIASLS
>Mature_307_residues
AILVLAEHDNAALKLDTAKVVNAARAIGDEVHVLVVGHQCGAVVQAAQALQGVSQVLVADASAYEAHLAENVAKLLVDLS
PQYGHILSAASSMGKDTLPRVAALLDVAQISEVIAVVSADTFVRPVYAGSALATVQSHDAIKVMTVRASAFDAVPEGNSA
VVTPLDKVFEAKTQFVSQSLTVSARPELGNAGIIVSGGRGMGSGENFGMLEQLADKLGAAVGASRAAVDAGFVPNDLQVG
QTGKIVAPNLYIAVGISGAIQHLAGMKDAKVIVAINKDPEAPIFQVADYGLEADLFEAVPELIASLS

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=306, Percent_Identity=56.2091503267974, Blast_Score=322, Evalue=2e-88,
Organism=Homo sapiens, GI189181759, Length=265, Percent_Identity=58.8679245283019, Blast_Score=295, Evalue=5e-80,
Organism=Escherichia coli, GI1786226, Length=300, Percent_Identity=30, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787990, Length=260, Percent_Identity=31.5384615384615, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87082157, Length=217, Percent_Identity=31.7972350230415, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17506929, Length=310, Percent_Identity=53.2258064516129, Blast_Score=310, Evalue=4e-85,
Organism=Saccharomyces cerevisiae, GI6325261, Length=270, Percent_Identity=46.2962962962963, Blast_Score=243, Evalue=2e-65,
Organism=Drosophila melanogaster, GI17136898, Length=311, Percent_Identity=58.8424437299035, Blast_Score=343, Evalue=1e-94,
Organism=Drosophila melanogaster, GI24652801, Length=311, Percent_Identity=58.8424437299035, Blast_Score=343, Evalue=1e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31549; Mature: 31418

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILVLAEHDNAALKLDTAKVVNAARAIGDEVHVLVVGHQCGAVVQAAQALQGVSQVLVA
CEEEEEEECCCCEEEEHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHH
DASAYEAHLAENVAKLLVDLSPQYGHILSAASSMGKDTLPRVAALLDVAQISEVIAVVSA
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
DTFVRPVYAGSALATVQSHDAIKVMTVRASAFDAVPEGNSAVVTPLDKVFEAKTQFVSQS
CHHHHHHHCCCCEEEECCCCCEEEEEEEHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHC
LTVSARPELGNAGIIVSGGRGMGSGENFGMLEQLADKLGAAVGASRAAVDAGFVPNDLQV
EEEEECCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEE
GQTGKIVAPNLYIAVGISGAIQHLAGMKDAKVIVAINKDPEAPIFQVADYGLEADLFEAV
CCCCCEECCCEEEEEECHHHHHHHCCCCCCEEEEEECCCCCCCEEHHHHCCCCHHHHHHH
PELIASLS
HHHHHCCC
>Mature Secondary Structure 
AILVLAEHDNAALKLDTAKVVNAARAIGDEVHVLVVGHQCGAVVQAAQALQGVSQVLVA
EEEEEEECCCCEEEEHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHH
DASAYEAHLAENVAKLLVDLSPQYGHILSAASSMGKDTLPRVAALLDVAQISEVIAVVSA
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
DTFVRPVYAGSALATVQSHDAIKVMTVRASAFDAVPEGNSAVVTPLDKVFEAKTQFVSQS
CHHHHHHHCCCCEEEECCCCCEEEEEEEHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHC
LTVSARPELGNAGIIVSGGRGMGSGENFGMLEQLADKLGAAVGASRAAVDAGFVPNDLQV
EEEEECCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEE
GQTGKIVAPNLYIAVGISGAIQHLAGMKDAKVIVAINKDPEAPIFQVADYGLEADLFEAV
CCCCCEECCCEEEEEECHHHHHHHCCCCCCEEEEEECCCCCCCEEHHHHCCCCHHHHHHH
PELIASLS
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]