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The map label for this gene is wecA [H]

Identifier: 120598298

GI number: 120598298

Start: 1668548

End: 1669621

Strand: Direct

Name: wecA [H]

Synonym: Sputw3181_1477

Alternate gene names: 120598298

Gene position: 1668548-1669621 (Clockwise)

Preceding gene: 120598297

Following gene: 120598301

Centisome position: 35.44

GC content: 41.43

Gene sequence:

>1074_bases
ATGTCAACAAATATCGCTGTTTTATTTGTTTTTTTAGTTTCTTTTATCAGTTTGTTTGTATTTCGCAAGGTCGCTCAACG
GATTGGTTTGGTTGATAAGCCGAATGAGCGTAAGCATCATAAAGGCCAGATCCCGCTTGTTGGGGGGATTTCTATTTTCT
TTACGATAATACTTGCCTTGTTCCTAACCCCTGAATTATTGCTGGCACCACAATTGTATGCAGGATGCGCTTTTATTCTT
GTGGTCATAGGGGCAATTGATGACCGTTATGATATCAGTTTTAAGTTTCGCCTTGTTGTCCAAGCTGCGGTTTCGATGCT
GATGATTGTGCTCGGTGAGCGCAGTTTACATAACTTAGGCTATTTGATGGGGAGTGAGGCGATACATTTGCCTGAGCCTA
TCAGCATATTGTTAACGGTTTTTGCAGTTATCGGTGCAATCAATGCGTTTAATATGGTTGACGGTATTGATGGTTTATTG
GGGGGATTAGCCTCTGTTACTTTTGGTGGCTTAGGCATTCTGTTCTATTTTAATGGCATGCAGGGTTTTGCTATTTTTTG
TGTGCTGCTCGTTACTGCGATGCTGCCTTATATCATGTTAAATTTAGGTTTTCCGTTCGGGCGACGTTTTAAAGTGTTTA
TGGGGGATGCGGGGAGTATTTTTATCGGCTTTACGGTGATTTGGTTACTGATTGTGGCAAGCCAAGGTGATCGAGCTACT
GCACTTCGCCCTGTGACCGCACTTTGGTTAATTGCGTTGCCGCTGATGGATATGGTGTGCATTATGATTCGCCGTATTCG
TAAAGGCCAATCGCCCTTTAAACCTGACCGCGAGCATTTGCATCATATCTGCCAACGTATGGGGTTGTCCTCTCATTCAT
CCTTGATGGTGATTTGTACCGCGGCAGCAATAATGGTAGCAGTCGGTATTTGGTCTGAACTTGCCAAAATTGATGAAAAT
ATTATGTTTTTAGCATTTTTAGCAACATTTGCTTTGTACTTTGGTTTAATCAATAACATCTGGCGTATTACGGCCTTTTG
GCGTAAAGATATAAAAATTTCTAAATCTATTTAA

Upstream 100 bases:

>100_bases
GATATAATCTAGCGACGCTTTAGCCATGAAGCTCCCTCGTTTTTAGAAGGCCAATGGCCCCGCTGCATTTTCCTTTTTTG
CATATTTTTAAGTGGTTTTT

Downstream 100 bases:

>100_bases
TACCTTAGTGAAATGTTGTTTTTTTTAATTTAGGCTGGCTTATCTGTTGTCGTTTCAACTGTTATAATCCAATGCCATTT
TTTTGAAATAAAATTTGATT

Product: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSTNIAVLFVFLVSFISLFVFRKVAQRIGLVDKPNERKHHKGQIPLVGGISIFFTIILALFLTPELLLAPQLYAGCAFIL
VVIGAIDDRYDISFKFRLVVQAAVSMLMIVLGERSLHNLGYLMGSEAIHLPEPISILLTVFAVIGAINAFNMVDGIDGLL
GGLASVTFGGLGILFYFNGMQGFAIFCVLLVTAMLPYIMLNLGFPFGRRFKVFMGDAGSIFIGFTVIWLLIVASQGDRAT
ALRPVTALWLIALPLMDMVCIMIRRIRKGQSPFKPDREHLHHICQRMGLSSHSSLMVICTAAAIMVAVGIWSELAKIDEN
IMFLAFLATFALYFGLINNIWRITAFWRKDIKISKSI

Sequences:

>Translated_357_residues
MSTNIAVLFVFLVSFISLFVFRKVAQRIGLVDKPNERKHHKGQIPLVGGISIFFTIILALFLTPELLLAPQLYAGCAFIL
VVIGAIDDRYDISFKFRLVVQAAVSMLMIVLGERSLHNLGYLMGSEAIHLPEPISILLTVFAVIGAINAFNMVDGIDGLL
GGLASVTFGGLGILFYFNGMQGFAIFCVLLVTAMLPYIMLNLGFPFGRRFKVFMGDAGSIFIGFTVIWLLIVASQGDRAT
ALRPVTALWLIALPLMDMVCIMIRRIRKGQSPFKPDREHLHHICQRMGLSSHSSLMVICTAAAIMVAVGIWSELAKIDEN
IMFLAFLATFALYFGLINNIWRITAFWRKDIKISKSI
>Mature_356_residues
STNIAVLFVFLVSFISLFVFRKVAQRIGLVDKPNERKHHKGQIPLVGGISIFFTIILALFLTPELLLAPQLYAGCAFILV
VIGAIDDRYDISFKFRLVVQAAVSMLMIVLGERSLHNLGYLMGSEAIHLPEPISILLTVFAVIGAINAFNMVDGIDGLLG
GLASVTFGGLGILFYFNGMQGFAIFCVLLVTAMLPYIMLNLGFPFGRRFKVFMGDAGSIFIGFTVIWLLIVASQGDRATA
LRPVTALWLIALPLMDMVCIMIRRIRKGQSPFKPDREHLHHICQRMGLSSHSSLMVICTAAAIMVAVGIWSELAKIDENI
MFLAFLATFALYFGLINNIWRITAFWRKDIKISKSI

Specific function: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55) [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. WecA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=326, Percent_Identity=51.5337423312883, Blast_Score=316, Evalue=2e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012750
- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 39555; Mature: 39424

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNIAVLFVFLVSFISLFVFRKVAQRIGLVDKPNERKHHKGQIPLVGGISIFFTIILAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHH
FLTPELLLAPQLYAGCAFILVVIGAIDDRYDISFKFRLVVQAAVSMLMIVLGERSLHNLG
HHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
YLMGSEAIHLPEPISILLTVFAVIGAINAFNMVDGIDGLLGGLASVTFGGLGILFYFNGM
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QGFAIFCVLLVTAMLPYIMLNLGFPFGRRFKVFMGDAGSIFIGFTVIWLLIVASQGDRAT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCH
ALRPVTALWLIALPLMDMVCIMIRRIRKGQSPFKPDREHLHHICQRMGLSSHSSLMVICT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHH
AAAIMVAVGIWSELAKIDENIMFLAFLATFALYFGLINNIWRITAFWRKDIKISKSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC
>Mature Secondary Structure 
STNIAVLFVFLVSFISLFVFRKVAQRIGLVDKPNERKHHKGQIPLVGGISIFFTIILAL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHH
FLTPELLLAPQLYAGCAFILVVIGAIDDRYDISFKFRLVVQAAVSMLMIVLGERSLHNLG
HHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
YLMGSEAIHLPEPISILLTVFAVIGAINAFNMVDGIDGLLGGLASVTFGGLGILFYFNGM
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QGFAIFCVLLVTAMLPYIMLNLGFPFGRRFKVFMGDAGSIFIGFTVIWLLIVASQGDRAT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCH
ALRPVTALWLIALPLMDMVCIMIRRIRKGQSPFKPDREHLHHICQRMGLSSHSSLMVICT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHH
AAAIMVAVGIWSELAKIDENIMFLAFLATFALYFGLINNIWRITAFWRKDIKISKSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]