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The map label for this gene is atoS [H]

Identifier: 120598247

GI number: 120598247

Start: 1611061

End: 1612143

Strand: Direct

Name: atoS [H]

Synonym: Sputw3181_1424

Alternate gene names: 120598247

Gene position: 1611061-1612143 (Clockwise)

Preceding gene: 120598246

Following gene: 120598248

Centisome position: 34.22

GC content: 44.6

Gene sequence:

>1083_bases
ATGTCAGCCCACCCACTAGCGCAAATCGAGACATTCAAGCACACTAGCAAACAATGGAACCAACTGCGTGAGGCCGCAAA
TATGTCCAATCGAATGGAACATATTTTACAAGCGATGCCCTCTGGCGTGGTGATTTTAAATGGTGATGGTATTGTCACTG
ACGCGAATCCCGTCGCGGTGGAATTGCTAGAGCACTCTCTATGTGGTGCTCGTTGGATTGATGTGATTCATAGTGCTTTT
GCACCTCAAGAAGATGATGGCCATGAAGTGTCTTTACGTAATGGTCGTCGAGTCAAATTAGCCATTACTCCTTTAACGCC
AGAGCCGGGTCAGTTAATCGTATTAACGGATCTGACTGAAACTCGTCTTTTACAAAAAAATATTTCACATCTGCAGCGGT
TATCTGCACTCGGTAAGATGGTGGCGACATTGGCCCATCAAGTCCGTACGCCACTCTCTGCGGCCTTGTTATATGCCTCT
AACTTAGCAAGCCCTAAATTATCAGACTCTGCCAAGATTAAGTTTCAACAGAAATTGGTTGATAGACTTAATGAATTGGA
AAGACAAGTTAACGATATGCTGTTGATGGCAAAAGGCCGTCAAGATGAGCTTGGCGAGTTAGTTTCTCTGAATGATGTGA
TGGTCAGTGTGATTGGAAACTGTGATCCAATTGCAGAGCAGCAAGGTTGCAAACTTTCCTTTACTGATACATCAAGTGGA
TTATTGCTGGCAAATTCAAGCGCGCTAAGTTCTGCAATTAATAACCTTGTCATCAACAGCCTCGAAGCTGGAGCGAGTCA
GATCCGTATCCTTGCCACAGAGTCAAAGGATCAATTAATGCTAGAGGTTATTGATAATGGCAAAGGGTTAGATGCGAAGA
TGCAGCAAAAAGTGATGGAACCTTTTTTCACCACCAAAGCTCAAGGGACAGGACTTGGATTAGCCGTTGTGCAATCGGTT
GTGCGTAATCATGGCGGAGAAATACAACTTCGCTGCCTACCGAATAAGGGCTGTACTGTTTCGTTAGTTTTCCCTCGTGC
AAAATCGGCGGTTGTATTGCCTTTGGAGAAAACCCATGTCTGA

Upstream 100 bases:

>100_bases
TTTAGTGTTATTTTATTGATTTTAATCCCTAAAAATGTCTTTTAATTTGGCATAGAACCTGCAGTCACTGCGTCATAAGC
AATTTTTTGACGGAGTGACT

Downstream 100 bases:

>100_bases
AGCCAAGTTACTCTTAGTTGAAGACGACGCCTCATTAAGGGAAGCCTTACTCGATACTTTATTACTTGCACAGTATGAAT
GTATTGATGTGGCTTGTGGT

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MSAHPLAQIETFKHTSKQWNQLREAANMSNRMEHILQAMPSGVVILNGDGIVTDANPVAVELLEHSLCGARWIDVIHSAF
APQEDDGHEVSLRNGRRVKLAITPLTPEPGQLIVLTDLTETRLLQKNISHLQRLSALGKMVATLAHQVRTPLSAALLYAS
NLASPKLSDSAKIKFQQKLVDRLNELERQVNDMLLMAKGRQDELGELVSLNDVMVSVIGNCDPIAEQQGCKLSFTDTSSG
LLLANSSALSSAINNLVINSLEAGASQIRILATESKDQLMLEVIDNGKGLDAKMQQKVMEPFFTTKAQGTGLGLAVVQSV
VRNHGGEIQLRCLPNKGCTVSLVFPRAKSAVVLPLEKTHV

Sequences:

>Translated_360_residues
MSAHPLAQIETFKHTSKQWNQLREAANMSNRMEHILQAMPSGVVILNGDGIVTDANPVAVELLEHSLCGARWIDVIHSAF
APQEDDGHEVSLRNGRRVKLAITPLTPEPGQLIVLTDLTETRLLQKNISHLQRLSALGKMVATLAHQVRTPLSAALLYAS
NLASPKLSDSAKIKFQQKLVDRLNELERQVNDMLLMAKGRQDELGELVSLNDVMVSVIGNCDPIAEQQGCKLSFTDTSSG
LLLANSSALSSAINNLVINSLEAGASQIRILATESKDQLMLEVIDNGKGLDAKMQQKVMEPFFTTKAQGTGLGLAVVQSV
VRNHGGEIQLRCLPNKGCTVSLVFPRAKSAVVLPLEKTHV
>Mature_359_residues
SAHPLAQIETFKHTSKQWNQLREAANMSNRMEHILQAMPSGVVILNGDGIVTDANPVAVELLEHSLCGARWIDVIHSAFA
PQEDDGHEVSLRNGRRVKLAITPLTPEPGQLIVLTDLTETRLLQKNISHLQRLSALGKMVATLAHQVRTPLSAALLYASN
LASPKLSDSAKIKFQQKLVDRLNELERQVNDMLLMAKGRQDELGELVSLNDVMVSVIGNCDPIAEQQGCKLSFTDTSSGL
LLANSSALSSAINNLVINSLEAGASQIRILATESKDQLMLEVIDNGKGLDAKMQQKVMEPFFTTKAQGTGLGLAVVQSVV
RNHGGEIQLRCLPNKGCTVSLVFPRAKSAVVLPLEKTHV

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=356, Percent_Identity=28.0898876404494, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1790436, Length=231, Percent_Identity=31.6017316017316, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1790346, Length=233, Percent_Identity=25.7510729613734, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786600, Length=349, Percent_Identity=22.9226361031519, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789808, Length=213, Percent_Identity=26.2910798122066, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39064; Mature: 38932

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAHPLAQIETFKHTSKQWNQLREAANMSNRMEHILQAMPSGVVILNGDGIVTDANPVAV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCHHHH
ELLEHSLCGARWIDVIHSAFAPQEDDGHEVSLRNGRRVKLAITPLTPEPGQLIVLTDLTE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCEEEEECCHH
TRLLQKNISHLQRLSALGKMVATLAHQVRTPLSAALLYASNLASPKLSDSAKIKFQQKLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
DRLNELERQVNDMLLMAKGRQDELGELVSLNDVMVSVIGNCDPIAEQQGCKLSFTDTSSG
HHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCCCEEEECCCCCC
LLLANSSALSSAINNLVINSLEAGASQIRILATESKDQLMLEVIDNGKGLDAKMQQKVME
EEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHEEHEECCCCCCCCHHHHHHHHH
PFFTTKAQGTGLGLAVVQSVVRNHGGEIQLRCLPNKGCTVSLVFPRAKSAVVLPLEKTHV
HHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCEEEEECHHCCC
>Mature Secondary Structure 
SAHPLAQIETFKHTSKQWNQLREAANMSNRMEHILQAMPSGVVILNGDGIVTDANPVAV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCHHHH
ELLEHSLCGARWIDVIHSAFAPQEDDGHEVSLRNGRRVKLAITPLTPEPGQLIVLTDLTE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCEEEEECCHH
TRLLQKNISHLQRLSALGKMVATLAHQVRTPLSAALLYASNLASPKLSDSAKIKFQQKLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
DRLNELERQVNDMLLMAKGRQDELGELVSLNDVMVSVIGNCDPIAEQQGCKLSFTDTSSG
HHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCCCEEEECCCCCC
LLLANSSALSSAINNLVINSLEAGASQIRILATESKDQLMLEVIDNGKGLDAKMQQKVME
EEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHEEHEECCCCCCCCHHHHHHHHH
PFFTTKAQGTGLGLAVVQSVVRNHGGEIQLRCLPNKGCTVSLVFPRAKSAVVLPLEKTHV
HHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCEEEEECHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]