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The map label for this gene is ntrC [H]

Identifier: 120598246

GI number: 120598246

Start: 1609518

End: 1610951

Strand: Direct

Name: ntrC [H]

Synonym: Sputw3181_1423

Alternate gene names: 120598246

Gene position: 1609518-1610951 (Clockwise)

Preceding gene: 120598245

Following gene: 120598247

Centisome position: 34.18

GC content: 43.03

Gene sequence:

>1434_bases
ATGATGCAAACAGATCAACGAATTTTACTTGTCGGAACCCCATCAGAGCGCTTAAGTCGCCTGTGTTGCATATTTGAATT
TTTGGGTGAGCAAATAGATGTTATTGCTCCCGAAAAATTAAATTCTTATCTCCAAGATACTCGTTATCGTGCTTTGGTTC
TCTTTACTGATACCATGCCAAGTGATGCAATAAAATTGCTTGCGACCCAGTTCGCGTGGCAACCGATATTATTGTTTGGC
GAGATAGGTGATTTTCAAGTATCCAATGTGCTTGGACAAATTGAAGAACCCTTAAGCTATCCCCAATTAACGGAACTGCT
GCACTTTTGCCAAGTTTACGGCCAAGTTAAACGTCCTCAAGTACCTACAAGTGCTAATCAAACTAAGCTTTTTAGAAGTT
TAGTTGGACGTAGTGATGGTATTGCTCATGTAAGACACTTGATCAATCAGGTCGCAACCTCTGATGCAACAGTGTTGGTG
TTAGGCCAGTCTGGTACGGGTAAAGAGGTCGTTGCTCGTAATATTCATTATCTTTCTGAACGTCGTGATGGTCCTTTTAT
TCCCGTTAACTGTGGCGCTATTCCTCCTGAATTACTTGAAAGTGAACTTTTTGGTCATGAAAAAGGTTCATTTACAGGGG
CTATTTGTTCCCGTAAAGGACGTTTTGAATTAGCCGAAGGTGGCACACTGTTTCTTGATGAAATCGGTGATATGCCCTTA
CAGATGCAAGTTAAATTGCTACGTGTGTTGCAAGAGCGAGTTTTTGAACGAGTGGGTGGCACTAAGACGATTAACGTCGA
TGTTCGAGTCGTCGCGGCTACCCATAGGGATCTAGAGAGCATGATCAGCGGTAATGAGTTCCGTGAGGACCTTTACTATC
GCCTTAATGTTTTCCCTATCGAAATGCCCGCCTTAAGCGAGCGTAAAGACGATGTACCTTTGTTGCTACAGGAGCTGGTG
AGCCGTGTATATAATGAGGGACGTGGTAAAGTGCGCTTTACCCAACGCGCAATAGAATCGTTAAAGGAACATGCATGGTC
TGGCAACGTTCGAGAGTTATCTAACTTAGTTGAGCGACTCACCATTTTATATCCAGGTGGTTTGGTTGATGTTAACGATC
TGCCTGTTAAATATCGCCACATTGATGTGCCAGAATACTGTGTTGAAATGAGTGAAGAGCAACAGGAGCGTGATGCGCTA
GCCTCTATCTTCACGAGTGAAGAGCCGGTTGAAATTCCTGAAACTCGTTTTCCAAATGAGTTACCACCTGAAGGTGTCAA
TCTTAAAGATTTGTTGGCAGAGCTTGAAATTGACATGATACGTCAAGCGCTTGAGCTACAGGATAATGTTGTTGCTCGAG
CTGCTGAAATGTTAGGTATTCGCCGTACAACTCTAGTTGAGAAAATGCGCAAATACGGAATGACAAAAGATTAG

Upstream 100 bases:

>100_bases
TGGCACAGATTGTTACATTGAATTTGTTAAGCTTTTACAGCAACTAATCATAAAATAATTAATGCAAATTAATACATATT
AGAGCTTTACGGCCTACTGA

Downstream 100 bases:

>100_bases
TATTTTGTGTTTAGTGTTATTTTATTGATTTTAATCCCTAAAAATGTCTTTTAATTTGGCATAGAACCTGCAGTCACTGC
GTCATAAGCAATTTTTTGAC

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MMQTDQRILLVGTPSERLSRLCCIFEFLGEQIDVIAPEKLNSYLQDTRYRALVLFTDTMPSDAIKLLATQFAWQPILLFG
EIGDFQVSNVLGQIEEPLSYPQLTELLHFCQVYGQVKRPQVPTSANQTKLFRSLVGRSDGIAHVRHLINQVATSDATVLV
LGQSGTGKEVVARNIHYLSERRDGPFIPVNCGAIPPELLESELFGHEKGSFTGAICSRKGRFELAEGGTLFLDEIGDMPL
QMQVKLLRVLQERVFERVGGTKTINVDVRVVAATHRDLESMISGNEFREDLYYRLNVFPIEMPALSERKDDVPLLLQELV
SRVYNEGRGKVRFTQRAIESLKEHAWSGNVRELSNLVERLTILYPGGLVDVNDLPVKYRHIDVPEYCVEMSEEQQERDAL
ASIFTSEEPVEIPETRFPNELPPEGVNLKDLLAELEIDMIRQALELQDNVVARAAEMLGIRRTTLVEKMRKYGMTKD

Sequences:

>Translated_477_residues
MMQTDQRILLVGTPSERLSRLCCIFEFLGEQIDVIAPEKLNSYLQDTRYRALVLFTDTMPSDAIKLLATQFAWQPILLFG
EIGDFQVSNVLGQIEEPLSYPQLTELLHFCQVYGQVKRPQVPTSANQTKLFRSLVGRSDGIAHVRHLINQVATSDATVLV
LGQSGTGKEVVARNIHYLSERRDGPFIPVNCGAIPPELLESELFGHEKGSFTGAICSRKGRFELAEGGTLFLDEIGDMPL
QMQVKLLRVLQERVFERVGGTKTINVDVRVVAATHRDLESMISGNEFREDLYYRLNVFPIEMPALSERKDDVPLLLQELV
SRVYNEGRGKVRFTQRAIESLKEHAWSGNVRELSNLVERLTILYPGGLVDVNDLPVKYRHIDVPEYCVEMSEEQQERDAL
ASIFTSEEPVEIPETRFPNELPPEGVNLKDLLAELEIDMIRQALELQDNVVARAAEMLGIRRTTLVEKMRKYGMTKD
>Mature_477_residues
MMQTDQRILLVGTPSERLSRLCCIFEFLGEQIDVIAPEKLNSYLQDTRYRALVLFTDTMPSDAIKLLATQFAWQPILLFG
EIGDFQVSNVLGQIEEPLSYPQLTELLHFCQVYGQVKRPQVPTSANQTKLFRSLVGRSDGIAHVRHLINQVATSDATVLV
LGQSGTGKEVVARNIHYLSERRDGPFIPVNCGAIPPELLESELFGHEKGSFTGAICSRKGRFELAEGGTLFLDEIGDMPL
QMQVKLLRVLQERVFERVGGTKTINVDVRVVAATHRDLESMISGNEFREDLYYRLNVFPIEMPALSERKDDVPLLLQELV
SRVYNEGRGKVRFTQRAIESLKEHAWSGNVRELSNLVERLTILYPGGLVDVNDLPVKYRHIDVPEYCVEMSEEQQERDAL
ASIFTSEEPVEIPETRFPNELPPEGVNLKDLLAELEIDMIRQALELQDNVVARAAEMLGIRRTTLVEKMRKYGMTKD

Specific function: Member of the two-component regulatory system ntrB/ntrC involved in the activation of nitrogen assimilatory genes such as glnA. NtrC is phosphorylated by ntrB and interacts with sigma-54 [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87082117, Length=341, Percent_Identity=43.6950146627566, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI1789087, Length=350, Percent_Identity=43.1428571428571, Blast_Score=268, Evalue=7e-73,
Organism=Escherichia coli, GI1788550, Length=327, Percent_Identity=44.0366972477064, Blast_Score=261, Evalue=8e-71,
Organism=Escherichia coli, GI1790437, Length=386, Percent_Identity=40.1554404145078, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1788905, Length=323, Percent_Identity=42.1052631578947, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1790299, Length=344, Percent_Identity=40.1162790697674, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1789233, Length=343, Percent_Identity=41.9825072886297, Blast_Score=235, Evalue=5e-63,
Organism=Escherichia coli, GI87082152, Length=231, Percent_Identity=46.7532467532467, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI87081872, Length=342, Percent_Identity=35.672514619883, Blast_Score=204, Evalue=8e-54,
Organism=Escherichia coli, GI1786524, Length=351, Percent_Identity=36.7521367521368, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1787583, Length=354, Percent_Identity=31.9209039548023, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI87081858, Length=329, Percent_Identity=30.3951367781155, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1789828, Length=250, Percent_Identity=35.6, Blast_Score=147, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR010114
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 54003; Mature: 54003

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQTDQRILLVGTPSERLSRLCCIFEFLGEQIDVIAPEKLNSYLQDTRYRALVLFTDTMP
CCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHCCCCEEEEEEECCCC
SDAIKLLATQFAWQPILLFGEIGDFQVSNVLGQIEEPLSYPQLTELLHFCQVYGQVKRPQ
HHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC
VPTSANQTKLFRSLVGRSDGIAHVRHLINQVATSDATVLVLGQSGTGKEVVARNIHYLSE
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHH
RRDGPFIPVNCGAIPPELLESELFGHEKGSFTGAICSRKGRFELAEGGTLFLDEIGDMPL
CCCCCEEEEECCCCCHHHHHHHHCCCCCCCCHHHHHCCCCCEEECCCCEEEEHHHCCCCH
QMQVKLLRVLQERVFERVGGTKTINVDVRVVAATHRDLESMISGNEFREDLYYRLNVFPI
HHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEHHHHHHHHHHCCHHHHHHHHEEEEEEEE
EMPALSERKDDVPLLLQELVSRVYNEGRGKVRFTQRAIESLKEHAWSGNVRELSNLVERL
ECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHH
TILYPGGLVDVNDLPVKYRHIDVPEYCVEMSEEQQERDALASIFTSEEPVEIPETRFPNE
HHCCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
LPPEGVNLKDLLAELEIDMIRQALELQDNVVARAAEMLGIRRTTLVEKMRKYGMTKD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MMQTDQRILLVGTPSERLSRLCCIFEFLGEQIDVIAPEKLNSYLQDTRYRALVLFTDTMP
CCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHCCCCEEEEEEECCCC
SDAIKLLATQFAWQPILLFGEIGDFQVSNVLGQIEEPLSYPQLTELLHFCQVYGQVKRPQ
HHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC
VPTSANQTKLFRSLVGRSDGIAHVRHLINQVATSDATVLVLGQSGTGKEVVARNIHYLSE
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHH
RRDGPFIPVNCGAIPPELLESELFGHEKGSFTGAICSRKGRFELAEGGTLFLDEIGDMPL
CCCCCEEEEECCCCCHHHHHHHHCCCCCCCCHHHHHCCCCCEEECCCCEEEEHHHCCCCH
QMQVKLLRVLQERVFERVGGTKTINVDVRVVAATHRDLESMISGNEFREDLYYRLNVFPI
HHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEHHHHHHHHHHCCHHHHHHHHEEEEEEEE
EMPALSERKDDVPLLLQELVSRVYNEGRGKVRFTQRAIESLKEHAWSGNVRELSNLVERL
ECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHH
TILYPGGLVDVNDLPVKYRHIDVPEYCVEMSEEQQERDALASIFTSEEPVEIPETRFPNE
HHCCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
LPPEGVNLKDLLAELEIDMIRQALELQDNVVARAAEMLGIRRTTLVEKMRKYGMTKD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2881918; 11481430; 8478331 [H]