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The map label for this gene is 120598205

Identifier: 120598205

GI number: 120598205

Start: 1572675

End: 1573724

Strand: Direct

Name: 120598205

Synonym: Sputw3181_1382

Alternate gene names: NA

Gene position: 1572675-1573724 (Clockwise)

Preceding gene: 120598204

Following gene: 120598206

Centisome position: 33.4

GC content: 42.29

Gene sequence:

>1050_bases
ATGCAGGTAATCAAAGTTGACCATTGTCACATCGGTCCTGGCCAGCCAGTATTTGTCATTGCAGAATTATCAGGAAACCA
TGGGCAATCGCTTGAAAAGGCAAAAGAGATGATATTGGCCGCCGCTGAGGCTGGGGCGAGCGCTATTAAGCTACAAACAT
ATACTCCTGATACTATTACCTTAAATGTTAGCCATGGTGAATTTTTTATTCAGGACCAAGACAACTTATGGAAAGGGAGA
AGCCTTTACGATCTCTATAGTGAGGCGATGACACCTTGGGAATGGCATCAGCCATTATTTGATTACGCTAAGTCGTTAGG
TTTAGTTGCGTTTAGTACGCCATTTGATTTAACGGCAGTGGAATACTTGGAAAAACTTAACGTACCTTGTTACAAAATAG
CTTCATTTGAAAATAATGATCATGCTTTACTGGCGGCTGTCGCGAAGACTGGTAAACCTGTGATTATGTCTACGGGAATG
GCTGAAATTCATGAGCTTGCTGAAGCTGTTACGGTATTAAAGCAACATGGATGTCGCGACTTGATTTTATTAAAGTGCAC
TAGCCATTATCCTGCTGAGCCAGTTGATGCCAATCTATCAACTATTCCTCATTTAGCACAACTATTTGATTGTCAAGTGG
GTTTATCTGACCACACGCAAGGGATTGGCGTTTCAATTGCTTCTGTGATTCTTGGAGGTACCGTAATTGAAAAACATTTT
GTTATCGATAGAAATGAAGGCGGTGTTGATAGTGAGTTTTCCCTTGAGCCGAGGGAGTTTAAGTCGCTCGTTATGGAAAC
CGAAAGAGCCCGTGTAGCCCTAGGACGAGTGCATTATGGATGTACAGCAAAGGAGATTGCATCAAGAAAATATCGGCGCT
CTCTTTATGTTAGTCGGGATATGAGCGCTGGCGATATTTTGACGGTTGATAATCTTCGTTCAGTTCGTCCTGGTTTAGGC
ATTGCTCCAAAATATTTACATCAATTACTCGGTAAAGCCGTCAAACAGGATATTGCAGCAGGTACGGCTATGTGTTGGGA
GTTTGTATAA

Upstream 100 bases:

>100_bases
TAATGCGCGACACATCATCAAGCCTAACGATGGTTTGCCCAGAGTTTTAGATGTCTTAAAAACACATTTGGCTACAACAG
GTATGGGAGAAAGTTAAATC

Downstream 100 bases:

>100_bases
CACTATTGTGTGGCAAACTCGAAAACTCATACCGCATAGAGTTGAGAATTAAATTGAATAATTATGGTGTAGAACTTCGC
GCTGTCGAAATGTGTGATTT

Product: N-acylneuraminate-9-phosphate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MQVIKVDHCHIGPGQPVFVIAELSGNHGQSLEKAKEMILAAAEAGASAIKLQTYTPDTITLNVSHGEFFIQDQDNLWKGR
SLYDLYSEAMTPWEWHQPLFDYAKSLGLVAFSTPFDLTAVEYLEKLNVPCYKIASFENNDHALLAAVAKTGKPVIMSTGM
AEIHELAEAVTVLKQHGCRDLILLKCTSHYPAEPVDANLSTIPHLAQLFDCQVGLSDHTQGIGVSIASVILGGTVIEKHF
VIDRNEGGVDSEFSLEPREFKSLVMETERARVALGRVHYGCTAKEIASRKYRRSLYVSRDMSAGDILTVDNLRSVRPGLG
IAPKYLHQLLGKAVKQDIAAGTAMCWEFV

Sequences:

>Translated_349_residues
MQVIKVDHCHIGPGQPVFVIAELSGNHGQSLEKAKEMILAAAEAGASAIKLQTYTPDTITLNVSHGEFFIQDQDNLWKGR
SLYDLYSEAMTPWEWHQPLFDYAKSLGLVAFSTPFDLTAVEYLEKLNVPCYKIASFENNDHALLAAVAKTGKPVIMSTGM
AEIHELAEAVTVLKQHGCRDLILLKCTSHYPAEPVDANLSTIPHLAQLFDCQVGLSDHTQGIGVSIASVILGGTVIEKHF
VIDRNEGGVDSEFSLEPREFKSLVMETERARVALGRVHYGCTAKEIASRKYRRSLYVSRDMSAGDILTVDNLRSVRPGLG
IAPKYLHQLLGKAVKQDIAAGTAMCWEFV
>Mature_349_residues
MQVIKVDHCHIGPGQPVFVIAELSGNHGQSLEKAKEMILAAAEAGASAIKLQTYTPDTITLNVSHGEFFIQDQDNLWKGR
SLYDLYSEAMTPWEWHQPLFDYAKSLGLVAFSTPFDLTAVEYLEKLNVPCYKIASFENNDHALLAAVAKTGKPVIMSTGM
AEIHELAEAVTVLKQHGCRDLILLKCTSHYPAEPVDANLSTIPHLAQLFDCQVGLSDHTQGIGVSIASVILGGTVIEKHF
VIDRNEGGVDSEFSLEPREFKSLVMETERARVALGRVHYGCTAKEIASRKYRRSLYVSRDMSAGDILTVDNLRSVRPGLG
IAPKYLHQLLGKAVKQDIAAGTAMCWEFV

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=328, Percent_Identity=32.3170731707317, Blast_Score=151, Evalue=9e-37,
Organism=Drosophila melanogaster, GI21357081, Length=251, Percent_Identity=32.6693227091633, Blast_Score=132, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 38367; Mature: 38367

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVIKVDHCHIGPGQPVFVIAELSGNHGQSLEKAKEMILAAAEAGASAIKLQTYTPDTIT
CCEEEECCEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCEEE
LNVSHGEFFIQDQDNLWKGRSLYDLYSEAMTPWEWHQPLFDYAKSLGLVAFSTPFDLTAV
EEEECCEEEEECCCCCCCCCHHHHHHHHHCCCHHHCCHHHHHHHHCCEEEECCCCCHHHH
EYLEKLNVPCYKIASFENNDHALLAAVAKTGKPVIMSTGMAEIHELAEAVTVLKQHGCRD
HHHHHCCCCEEEEECCCCCCCEEEEEEHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCE
LILLKCTSHYPAEPVDANLSTIPHLAQLFDCQVGLSDHTQGIGVSIASVILGGTVIEKHF
EEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHEEEEE
VIDRNEGGVDSEFSLEPREFKSLVMETERARVALGRVHYGCTAKEIASRKYRRSLYVSRD
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHEEECC
MSAGDILTVDNLRSVRPGLGIAPKYLHQLLGKAVKQDIAAGTAMCWEFV
CCCCCEEEECCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQVIKVDHCHIGPGQPVFVIAELSGNHGQSLEKAKEMILAAAEAGASAIKLQTYTPDTIT
CCEEEECCEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCEEE
LNVSHGEFFIQDQDNLWKGRSLYDLYSEAMTPWEWHQPLFDYAKSLGLVAFSTPFDLTAV
EEEECCEEEEECCCCCCCCCHHHHHHHHHCCCHHHCCHHHHHHHHCCEEEECCCCCHHHH
EYLEKLNVPCYKIASFENNDHALLAAVAKTGKPVIMSTGMAEIHELAEAVTVLKQHGCRD
HHHHHCCCCEEEEECCCCCCCEEEEEEHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCE
LILLKCTSHYPAEPVDANLSTIPHLAQLFDCQVGLSDHTQGIGVSIASVILGGTVIEKHF
EEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHEEEEE
VIDRNEGGVDSEFSLEPREFKSLVMETERARVALGRVHYGCTAKEIASRKYRRSLYVSRD
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHEEECC
MSAGDILTVDNLRSVRPGLGIAPKYLHQLLGKAVKQDIAAGTAMCWEFV
CCCCCEEEECCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]