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The map label for this gene is tadA [H]

Identifier: 120598186

GI number: 120598186

Start: 1545257

End: 1545751

Strand: Direct

Name: tadA [H]

Synonym: Sputw3181_1363

Alternate gene names: 120598186

Gene position: 1545257-1545751 (Clockwise)

Preceding gene: 120598185

Following gene: 120598188

Centisome position: 32.82

GC content: 50.3

Gene sequence:

>495_bases
TTGGACGAATATTGGATGCAAGTCGCGATGCAGATGGCAGAGAAGGCTGAAGCTGCGGGCGAGGTGCCTGTGGGTGCGGT
TCTGGTCAAAGACGGTCAGCAGATTGCGACGGGTTACAATTTATCCATTAGCCAACACGATCCTAGCGCCCATGCAGAGA
TCCTCTGTTTACGTAGCGCAGGTAAAAAGCTCGAAAACTATCGTCTTTTGGATGCCACCCTTTATATAACCCTTGAACCT
TGCGCTATGTGTGCAGGCGCTATGGTGCACAGCCGGATCGCGCGGGTGGTTTATGGTGCTCGGGATGAAAAAACGGGTGC
TGCGGGGACTGTGGTGAATTTACTGCAACATCCGGCGTTTAATCATCAAGTTGAAGTGACATCAGGTGTATTAGCTGAGG
CTTGTAGCGCACAGTTGAGTCGTTTTTTTAAACGCCGTAGGGATGAAAAGAAGGCTTTAAAACTGGCTCAAAGGGCGCAG
CAAGGGATAGAGTAA

Upstream 100 bases:

>100_bases
TTAGGCTGAATGACTCAGCTGTGAAATATCTGTGTTTGACTGATATAATCCCGCTTTACTTTTGGCTTAAAGAGAGAAAG
TGTCAGTGGAGCAAACTGAG

Downstream 100 bases:

>100_bases
AAGCGATAGAAAGTGTTTTTAGTCTTGAGATTGGATAAAAGTAAAGAAAAGTTTTTGGCGGTTTAATATTCGACGATGGC
GTATTTTTAGCAAAGTACGA

Product: CMP/dCMP deaminase, zinc-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MDEYWMQVAMQMAEKAEAAGEVPVGAVLVKDGQQIATGYNLSISQHDPSAHAEILCLRSAGKKLENYRLLDATLYITLEP
CAMCAGAMVHSRIARVVYGARDEKTGAAGTVVNLLQHPAFNHQVEVTSGVLAEACSAQLSRFFKRRRDEKKALKLAQRAQ
QGIE

Sequences:

>Translated_164_residues
MDEYWMQVAMQMAEKAEAAGEVPVGAVLVKDGQQIATGYNLSISQHDPSAHAEILCLRSAGKKLENYRLLDATLYITLEP
CAMCAGAMVHSRIARVVYGARDEKTGAAGTVVNLLQHPAFNHQVEVTSGVLAEACSAQLSRFFKRRRDEKKALKLAQRAQ
QGIE
>Mature_164_residues
MDEYWMQVAMQMAEKAEAAGEVPVGAVLVKDGQQIATGYNLSISQHDPSAHAEILCLRSAGKKLENYRLLDATLYITLEP
CAMCAGAMVHSRIARVVYGARDEKTGAAGTVVNLLQHPAFNHQVEVTSGVLAEACSAQLSRFFKRRRDEKKALKLAQRAQ
QGIE

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=168, Percent_Identity=30.3571428571429, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI19923945, Length=152, Percent_Identity=32.8947368421053, Blast_Score=70, Evalue=9e-13,
Organism=Escherichia coli, GI145693172, Length=155, Percent_Identity=60, Blast_Score=206, Evalue=9e-55,
Organism=Escherichia coli, GI1786616, Length=154, Percent_Identity=31.8181818181818, Blast_Score=65, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17554608, Length=119, Percent_Identity=36.1344537815126, Blast_Score=87, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17541138, Length=148, Percent_Identity=31.7567567567568, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6325319, Length=100, Percent_Identity=37, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322425, Length=158, Percent_Identity=31.0126582278481, Blast_Score=65, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=31.5068493150685, Blast_Score=76, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 17930; Mature: 17930

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEYWMQVAMQMAEKAEAAGEVPVGAVLVKDGQQIATGYNLSISQHDPSAHAEILCLRSA
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEECCCCCEEECCCCCCCHHHHHHHHHH
GKKLENYRLLDATLYITLEPCAMCAGAMVHSRIARVVYGARDEKTGAAGTVVNLLQHPAF
HHHHHCEEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
NHQVEVTSGVLAEACSAQLSRFFKRRRDEKKALKLAQRAQQGIE
CCEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDEYWMQVAMQMAEKAEAAGEVPVGAVLVKDGQQIATGYNLSISQHDPSAHAEILCLRSA
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEECCCCCEEECCCCCCCHHHHHHHHHH
GKKLENYRLLDATLYITLEPCAMCAGAMVHSRIARVVYGARDEKTGAAGTVVNLLQHPAF
HHHHHCEEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
NHQVEVTSGVLAEACSAQLSRFFKRRRDEKKALKLAQRAQQGIE
CCEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]