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The map label for this gene is tcpI [H]

Identifier: 120598112

GI number: 120598112

Start: 1471490

End: 1473058

Strand: Direct

Name: tcpI [H]

Synonym: Sputw3181_1289

Alternate gene names: 120598112

Gene position: 1471490-1473058 (Clockwise)

Preceding gene: 120598110

Following gene: 120598113

Centisome position: 31.25

GC content: 43.85

Gene sequence:

>1569_bases
ATGGAAATACAGCATAAAATTATGGTTGCGCTCAGTTTTATTCTGGTCATGCTGTGCTGCTTATTGCTTGCAAGACTCGG
TATACCTAATGTTGTGCAAGCTATTATTTTAGGTTTCTTAGCTTGCGGCCTCGTCTTGTGGGTTGTGTTACGTTCATCTG
CCACGCAAGCACAGCTAGATGAACTTATTGCTCAAAAGCTGAAATTGCAAAATACACCTGCGCACGATATCAGTGTGCAA
ACGAGTAAAATAGCCATTGGTTCGGCAGAGGTTTCACATTTTATTGATTTACTTAATAAATCGATAGAATCAAATGGTGA
GCATGCCAGTGCTATTGCGGTAGCCGCAGAACAATTAAGCCATACCACTGCTCAATTAGGGGATAATGCGGCTGATATTT
TAGTTCAGGCTCAGGAGGCTGAACGATTTAGTGTGCAAGGCCGAACCCAAGCGCAAAAAGGGGTAGAGTCTATTCATTCA
CTTAGTGCGGACATTGATACTGCTGCCGAACAAGTTCAGGCTTTGAAGTCTAAAGCAGAACAAATCCAAAAAATCACTGA
AGTTATCAATTCCGTAGCAGAGCAAACCAATTTGCTTGCACTAAATGCAGCCATTGAAGCAGCAAGAGCTGGAGAGCAGG
GGCGAGGTTTTGCAGTGGTAGCAGATGAAGTCCGAAGCCTTGCGGGCAAAACTGCAGTTGCAACCCAAGATATTGGTAAG
ATGTTATTAGAAATTCGCAGCGAGACCGATAAAACCTCTGGTTTAATGGAGCGAGTCGTTTCTCAAACCGCGGACGTGGT
GGTTGCTATGGGGGAATTAGACGAACACTTTACCGAAATATCAACATCTGTGACACGTTCAGCCCATGCTTTAGGTGAGA
TGGAAGACTCGCTAAAGCAATACAATCATACGACAAACGAGATTAGTCGCTCCGTCTCACAGATCCGCGACTCATTGAAT
TCCACGGGTAAGCAGAGCCACAAAGTGTCAGAGCAGGCGTTTACCTTGTCATTAACAACCGAGGGCATTTTTAAGGCATT
GTCTCATTGGGATACACAAACCTTTGATCAGCAAGTTTTATTATTGGCCAATGATGCTGCTAAAGCCTGTGGAGAGAAAC
TTGCTCAAGGTATCGAAAATGGCAGTTTTAGCGAGGCTGATTTATTCAATCCCCAATATCAACCGATAGCAAATACCAAA
CCCCAGAAATATAGCACGGCTTTTGACCGTTATACCGATCAGCATTTCCCTGGGATTCAAGAACCTATTTTAGAGAAGCA
CAGTGAAATTATTTATGCTGGGGCTGTAGATAAAAAAGGCTATTTTCCGACACACAATAAACGCTTTAGCCAAGCGCTTA
CAGGCCGGGCAGAGATGGATATAGTACATAATCGAACCAAACGGTTGTTTAACGATCCAACGGGGATCCGCTGTGGTACA
CATACTGAGCCTGTGTTATTACAAACCTATAAACGGGATACAGGGGAGGTAATGCACGACTTGTCTGTGCCAATTTATGT
GAATGGGAAACACTGGGGCGGATTTAGGGTAGGGTTCAAAGCTAAATAA

Upstream 100 bases:

>100_bases
TAAGCTTTCTAAAATGAAAATACAGTATGGCTTGACCCTTGGATAAGTCTCTTCGTTGGCCGTTTCATTTTTCACCTTGT
GTCCTTGCGAGATTATATAT

Downstream 100 bases:

>100_bases
AGGTATATCGTCAGGTATCCGTTTATTTATGTTAAACGGGAATGGGATCGGATATTTTATAAACGTGATCAGTTACCCGT
AATGACTTTATGGTATGTAA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: TCP pilus biosynthesis protein tcpI [H]

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MEIQHKIMVALSFILVMLCCLLLARLGIPNVVQAIILGFLACGLVLWVVLRSSATQAQLDELIAQKLKLQNTPAHDISVQ
TSKIAIGSAEVSHFIDLLNKSIESNGEHASAIAVAAEQLSHTTAQLGDNAADILVQAQEAERFSVQGRTQAQKGVESIHS
LSADIDTAAEQVQALKSKAEQIQKITEVINSVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAGKTAVATQDIGK
MLLEIRSETDKTSGLMERVVSQTADVVVAMGELDEHFTEISTSVTRSAHALGEMEDSLKQYNHTTNEISRSVSQIRDSLN
STGKQSHKVSEQAFTLSLTTEGIFKALSHWDTQTFDQQVLLLANDAAKACGEKLAQGIENGSFSEADLFNPQYQPIANTK
PQKYSTAFDRYTDQHFPGIQEPILEKHSEIIYAGAVDKKGYFPTHNKRFSQALTGRAEMDIVHNRTKRLFNDPTGIRCGT
HTEPVLLQTYKRDTGEVMHDLSVPIYVNGKHWGGFRVGFKAK

Sequences:

>Translated_522_residues
MEIQHKIMVALSFILVMLCCLLLARLGIPNVVQAIILGFLACGLVLWVVLRSSATQAQLDELIAQKLKLQNTPAHDISVQ
TSKIAIGSAEVSHFIDLLNKSIESNGEHASAIAVAAEQLSHTTAQLGDNAADILVQAQEAERFSVQGRTQAQKGVESIHS
LSADIDTAAEQVQALKSKAEQIQKITEVINSVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAGKTAVATQDIGK
MLLEIRSETDKTSGLMERVVSQTADVVVAMGELDEHFTEISTSVTRSAHALGEMEDSLKQYNHTTNEISRSVSQIRDSLN
STGKQSHKVSEQAFTLSLTTEGIFKALSHWDTQTFDQQVLLLANDAAKACGEKLAQGIENGSFSEADLFNPQYQPIANTK
PQKYSTAFDRYTDQHFPGIQEPILEKHSEIIYAGAVDKKGYFPTHNKRFSQALTGRAEMDIVHNRTKRLFNDPTGIRCGT
HTEPVLLQTYKRDTGEVMHDLSVPIYVNGKHWGGFRVGFKAK
>Mature_522_residues
MEIQHKIMVALSFILVMLCCLLLARLGIPNVVQAIILGFLACGLVLWVVLRSSATQAQLDELIAQKLKLQNTPAHDISVQ
TSKIAIGSAEVSHFIDLLNKSIESNGEHASAIAVAAEQLSHTTAQLGDNAADILVQAQEAERFSVQGRTQAQKGVESIHS
LSADIDTAAEQVQALKSKAEQIQKITEVINSVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAGKTAVATQDIGK
MLLEIRSETDKTSGLMERVVSQTADVVVAMGELDEHFTEISTSVTRSAHALGEMEDSLKQYNHTTNEISRSVSQIRDSLN
STGKQSHKVSEQAFTLSLTTEGIFKALSHWDTQTFDQQVLLLANDAAKACGEKLAQGIENGSFSEADLFNPQYQPIANTK
PQKYSTAFDRYTDQHFPGIQEPILEKHSEIIYAGAVDKKGYFPTHNKRFSQALTGRAEMDIVHNRTKRLFNDPTGIRCGT
HTEPVLLQTYKRDTGEVMHDLSVPIYVNGKHWGGFRVGFKAK

Specific function: May function as an environmental regulator of TCP biogenesis. Negatively regulates the synthesis of the major pilin subunit of TCP (tcpA) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=239, Percent_Identity=35.5648535564854, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788194, Length=240, Percent_Identity=31.25, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI2367378, Length=234, Percent_Identity=32.0512820512821, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1789453, Length=236, Percent_Identity=32.2033898305085, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788195, Length=232, Percent_Identity=34.051724137931, Blast_Score=93, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 57001; Mature: 57001

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIQHKIMVALSFILVMLCCLLLARLGIPNVVQAIILGFLACGLVLWVVLRSSATQAQLD
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ELIAQKLKLQNTPAHDISVQTSKIAIGSAEVSHFIDLLNKSIESNGEHASAIAVAAEQLS
HHHHHHHHCCCCCCCCCEEEHHEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
HTTAQLGDNAADILVQAQEAERFSVQGRTQAQKGVESIHSLSADIDTAAEQVQALKSKAE
HHHHHHCCCHHHHHEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIQKITEVINSVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAGKTAVATQDIGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCHHHHHHHHHH
MLLEIRSETDKTSGLMERVVSQTADVVVAMGELDEHFTEISTSVTRSAHALGEMEDSLKQ
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YNHTTNEISRSVSQIRDSLNSTGKQSHKVSEQAFTLSLTTEGIFKALSHWDTQTFDQQVL
HCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEEECHHHHHHHHHHCCCHHHCCCEE
LLANDAAKACGEKLAQGIENGSFSEADLFNPQYQPIANTKPQKYSTAFDRYTDQHFPGIQ
EEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCH
EPILEKHSEIIYAGAVDKKGYFPTHNKRFSQALTGRAEMDIVHNRTKRLFNDPTGIRCGT
HHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCC
HTEPVLLQTYKRDTGEVMHDLSVPIYVNGKHWGGFRVGFKAK
CCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEECCCCCC
>Mature Secondary Structure
MEIQHKIMVALSFILVMLCCLLLARLGIPNVVQAIILGFLACGLVLWVVLRSSATQAQLD
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ELIAQKLKLQNTPAHDISVQTSKIAIGSAEVSHFIDLLNKSIESNGEHASAIAVAAEQLS
HHHHHHHHCCCCCCCCCEEEHHEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
HTTAQLGDNAADILVQAQEAERFSVQGRTQAQKGVESIHSLSADIDTAAEQVQALKSKAE
HHHHHHCCCHHHHHEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIQKITEVINSVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAGKTAVATQDIGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCHHHHHHHHHH
MLLEIRSETDKTSGLMERVVSQTADVVVAMGELDEHFTEISTSVTRSAHALGEMEDSLKQ
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YNHTTNEISRSVSQIRDSLNSTGKQSHKVSEQAFTLSLTTEGIFKALSHWDTQTFDQQVL
HCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEEECHHHHHHHHHHCCCHHHCCCEE
LLANDAAKACGEKLAQGIENGSFSEADLFNPQYQPIANTKPQKYSTAFDRYTDQHFPGIQ
EEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCH
EPILEKHSEIIYAGAVDKKGYFPTHNKRFSQALTGRAEMDIVHNRTKRLFNDPTGIRCGT
HHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCC
HTEPVLLQTYKRDTGEVMHDLSVPIYVNGKHWGGFRVGFKAK
CCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8005659 [H]