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The map label for this gene is aer [H]

Identifier: 120598109

GI number: 120598109

Start: 1468034

End: 1469650

Strand: Direct

Name: aer [H]

Synonym: Sputw3181_1286

Alternate gene names: 120598109

Gene position: 1468034-1469650 (Clockwise)

Preceding gene: 120598104

Following gene: 120598110

Centisome position: 31.18

GC content: 45.64

Gene sequence:

>1617_bases
TTGGCAAAATGCCATTCACATTTTTACCGAGAGCCAACCCTTAACCCTATGCAAACACATCCTACAAAAGGTGAGAAACA
CCTGTCTGATAATGCGATTTTACTCTCTACCACGGATTTGAAGGGAAACATTAAGTATGTTAACCAGACATTTTCAAATA
TCAGTGAGTTTAACGTCGATGAGTTGCAGGGGAGTCCCCATAATATCGTGCGTCATCCCGATATGCCTGCTGCGGCATTT
AAGATGCTCTGGGAGCGGATAAAGAGTGGCAAGCCCTGGATGGGGATAGTTAAAAATCGCACTAAGAGTGGCGATTACTA
TTGGGTTAATGCCTACGTTGCTCCTGTATATGAGAATGGTGAAATTCATGAATATCAATCTGTTCGCCGCCAAGCGACGC
CTGAGCAGATTAAAGCTGCCGAGAGTATTTATCAGGATATTAATCAAGGCAAAAAACCTAAAGCTTTGAAAAAAGACAAG
TTAGGATTTAGTGGAAAAATACTGGCTGCGATGCTTTTCTCCATTATGATCACCGCTTATGTTGCCAGTTATTCTCCATT
ACTTGCGGCTTTTAGTGGCGGGATATTTGCGGTTATTGCTTGGTTTGTTTTGATGAAGCCACTACATAATCTTGTCTCTA
TTGCGACAAATATTATTGATGATCCTGTTGCTATGGGGGTGTATACGGGGCGTCAAGATGAAATCGGTAAGCTGGATCTG
GCTTTACGCTTCTTAATCACAGAAATTGGTGGTGTGGTCGGGCGAATGGCTGATTCTGCGAGTGAAATTCAGCAGCAGAG
TGTCAGCTTAAAGCAAACCATTACTAATACATGGGAACATGCTGATAGTCAGAGTGAACAAACGACCCAAGCCGCCACGG
CAATGGAGCAAATGAGTGCGAGTTTTGCTGAAGTGACGGGCAATATTCATCGTACCGCTTCGGAAATGGTATCTAGCCAT
CAGGCGGCTCAGCGTGGACATTCACGTCTTGAAACGGTAATCGATGCGATACATCAGTTGAGTGTACAGGTAAGCCACTT
TTCAGATGTGGTTGCAACGATTGAAGAAGATAGTCGTGCCATTCATCAGGTATTAGAAGTGATCCGCGCTATTGCCGATC
AAACCAATCTATTAGCCCTTAATGCTGCGATTGAGGCGGCTCGTGCTGGGGAGAGTGGTCGTGGTTTTGCTGTTGTTGCT
GATGAAGTACGGCAACTATCAAGCCGTACGAGTCAGTCAACCTCACAAATAGAAATGATTGTAGGCCGATTTAGGGACAG
CACCCAAAAAGCAACGTCCACCATGATGGCAGGACAAGAGCAGGTCAAACGGTCCGTTGCGCTTGCAGAGGATGCCAGTG
TGGCTTTTGGTGAGTTATTGTCATCGATTACGCGGATCAACTCTTTGAGCGATGATAATGCCGCAGCAATGACCCAACAG
GCGTCGGTTGCTGCCGAGATCAGTCGCGCAATTCATGTCATCAGTGACTTAGCTCATCAGAGTCTACAACAAACCCAAGA
TGCAGCGGCGAGGGGCGACCAAGTCTCGCGTTTATCCACTAAAACCCATCATTTATCCCAGCAGTTTTGGCAACAGAGTG
TACAACGTAAATATTGA

Upstream 100 bases:

>100_bases
TTTATAGGTGCTTGTTGGTTTTTATGCTAATGCTTGTTTAGCATTTGGTTAACTTTTCTACTGTCATTGTGAGCTTAATC
AACGTAGGTTGACTTTCCTT

Downstream 100 bases:

>100_bases
GGCTGATTTGGTATTAGCTTAGCGGTTGATTTATAAATTGTTAGTTGTATGTAAATCAACCGCTTGATTTTATTTTCTGC
ACTTATCCCATGATGTTTCT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 538; Mature: 537

Protein sequence:

>538_residues
MAKCHSHFYREPTLNPMQTHPTKGEKHLSDNAILLSTTDLKGNIKYVNQTFSNISEFNVDELQGSPHNIVRHPDMPAAAF
KMLWERIKSGKPWMGIVKNRTKSGDYYWVNAYVAPVYENGEIHEYQSVRRQATPEQIKAAESIYQDINQGKKPKALKKDK
LGFSGKILAAMLFSIMITAYVASYSPLLAAFSGGIFAVIAWFVLMKPLHNLVSIATNIIDDPVAMGVYTGRQDEIGKLDL
ALRFLITEIGGVVGRMADSASEIQQQSVSLKQTITNTWEHADSQSEQTTQAATAMEQMSASFAEVTGNIHRTASEMVSSH
QAAQRGHSRLETVIDAIHQLSVQVSHFSDVVATIEEDSRAIHQVLEVIRAIADQTNLLALNAAIEAARAGESGRGFAVVA
DEVRQLSSRTSQSTSQIEMIVGRFRDSTQKATSTMMAGQEQVKRSVALAEDASVAFGELLSSITRINSLSDDNAAAMTQQ
ASVAAEISRAIHVISDLAHQSLQQTQDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY

Sequences:

>Translated_538_residues
MAKCHSHFYREPTLNPMQTHPTKGEKHLSDNAILLSTTDLKGNIKYVNQTFSNISEFNVDELQGSPHNIVRHPDMPAAAF
KMLWERIKSGKPWMGIVKNRTKSGDYYWVNAYVAPVYENGEIHEYQSVRRQATPEQIKAAESIYQDINQGKKPKALKKDK
LGFSGKILAAMLFSIMITAYVASYSPLLAAFSGGIFAVIAWFVLMKPLHNLVSIATNIIDDPVAMGVYTGRQDEIGKLDL
ALRFLITEIGGVVGRMADSASEIQQQSVSLKQTITNTWEHADSQSEQTTQAATAMEQMSASFAEVTGNIHRTASEMVSSH
QAAQRGHSRLETVIDAIHQLSVQVSHFSDVVATIEEDSRAIHQVLEVIRAIADQTNLLALNAAIEAARAGESGRGFAVVA
DEVRQLSSRTSQSTSQIEMIVGRFRDSTQKATSTMMAGQEQVKRSVALAEDASVAFGELLSSITRINSLSDDNAAAMTQQ
ASVAAEISRAIHVISDLAHQSLQQTQDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY
>Mature_537_residues
AKCHSHFYREPTLNPMQTHPTKGEKHLSDNAILLSTTDLKGNIKYVNQTFSNISEFNVDELQGSPHNIVRHPDMPAAAFK
MLWERIKSGKPWMGIVKNRTKSGDYYWVNAYVAPVYENGEIHEYQSVRRQATPEQIKAAESIYQDINQGKKPKALKKDKL
GFSGKILAAMLFSIMITAYVASYSPLLAAFSGGIFAVIAWFVLMKPLHNLVSIATNIIDDPVAMGVYTGRQDEIGKLDLA
LRFLITEIGGVVGRMADSASEIQQQSVSLKQTITNTWEHADSQSEQTTQAATAMEQMSASFAEVTGNIHRTASEMVSSHQ
AAQRGHSRLETVIDAIHQLSVQVSHFSDVVATIEEDSRAIHQVLEVIRAIADQTNLLALNAAIEAARAGESGRGFAVVAD
EVRQLSSRTSQSTSQIEMIVGRFRDSTQKATSTMMAGQEQVKRSVALAEDASVAFGELLSSITRINSLSDDNAAAMTQQA
SVAAEISRAIHVISDLAHQSLQQTQDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=516, Percent_Identity=31.5891472868217, Blast_Score=238, Evalue=7e-64,
Organism=Escherichia coli, GI2367378, Length=354, Percent_Identity=26.8361581920904, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1787690, Length=396, Percent_Identity=27.020202020202, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1788194, Length=315, Percent_Identity=30.1587301587302, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788195, Length=270, Percent_Identity=30, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 59186; Mature: 59055

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKCHSHFYREPTLNPMQTHPTKGEKHLSDNAILLSTTDLKGNIKYVNQTFSNISEFNVD
CCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHH
ELQGSPHNIVRHPDMPAAAFKMLWERIKSGKPWMGIVKNRTKSGDYYWVNAYVAPVYENG
HHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEEEEEEEEECCC
EIHEYQSVRRQATPEQIKAAESIYQDINQGKKPKALKKDKLGFSGKILAAMLFSIMITAY
CHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHH
VASYSPLLAAFSGGIFAVIAWFVLMKPLHNLVSIATNIIDDPVAMGVYTGRQDEIGKLDL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEECCCCCCHHHHHH
ALRFLITEIGGVVGRMADSASEIQQQSVSLKQTITNTWEHADSQSEQTTQAATAMEQMSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SFAEVTGNIHRTASEMVSSHQAAQRGHSRLETVIDAIHQLSVQVSHFSDVVATIEEDSRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHQVLEVIRAIADQTNLLALNAAIEAARAGESGRGFAVVADEVRQLSSRTSQSTSQIEMI
HHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCHHHHHHHH
VGRFRDSTQKATSTMMAGQEQVKRSVALAEDASVAFGELLSSITRINSLSDDNAAAMTQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ASVAAEISRAIHVISDLAHQSLQQTQDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKCHSHFYREPTLNPMQTHPTKGEKHLSDNAILLSTTDLKGNIKYVNQTFSNISEFNVD
CCHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHH
ELQGSPHNIVRHPDMPAAAFKMLWERIKSGKPWMGIVKNRTKSGDYYWVNAYVAPVYENG
HHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEEEEEEEEECCC
EIHEYQSVRRQATPEQIKAAESIYQDINQGKKPKALKKDKLGFSGKILAAMLFSIMITAY
CHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHH
VASYSPLLAAFSGGIFAVIAWFVLMKPLHNLVSIATNIIDDPVAMGVYTGRQDEIGKLDL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEECCCCCCHHHHHH
ALRFLITEIGGVVGRMADSASEIQQQSVSLKQTITNTWEHADSQSEQTTQAATAMEQMSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SFAEVTGNIHRTASEMVSSHQAAQRGHSRLETVIDAIHQLSVQVSHFSDVVATIEEDSRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHQVLEVIRAIADQTNLLALNAAIEAARAGESGRGFAVVADEVRQLSSRTSQSTSQIEMI
HHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCHHHHHHHH
VGRFRDSTQKATSTMMAGQEQVKRSVALAEDASVAFGELLSSITRINSLSDDNAAAMTQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ASVAAEISRAIHVISDLAHQSLQQTQDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]