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The map label for this gene is serB [H]

Identifier: 120598017

GI number: 120598017

Start: 1345380

End: 1346375

Strand: Direct

Name: serB [H]

Synonym: Sputw3181_1194

Alternate gene names: 120598017

Gene position: 1345380-1346375 (Clockwise)

Preceding gene: 120598015

Following gene: 120598018

Centisome position: 28.57

GC content: 45.98

Gene sequence:

>996_bases
ATGGAAAGCTTAAACCAAGATGCGCTTTTTTTATGGTTAGCGACTAACCCTTCGCCACGGTTTGAATACCAAGGGCATCT
CTTTGGGGCTTATCAAGAGTCTGATACTCCACCATCGGGAACGCTTGTGCGTGTTAGGATTATTTATCAAGAGATAAGTG
CACAAAAATCCCTTGCTGAGTGGCTAATCGCATTAGCGAGTACGCTCAAGTTACCCCATGTTTATATTGCGTCAATCAAA
CGTCAAGTGGCTTTGCATTGTATTGAACTTGCTTTACCCCTTGAGCTATCGTCCGATAGGGTAACGATGTTTCCCTATGA
TTTGGCAGAGTTGCATGTTTTTAATACTGATTTACCCAAATTAAGTGTACCAGGGTTACTTGTGATGGATATGGATTCAA
CTGCGATTCAAATCGAATGCATCGACGAATTAGCCGCGATGGCCGGCGTTGGGGAGCAAGTGGCGGCAATAACCGAAAGG
GCCATGCAGGGGGAACTTGATTTTGAGCAGAGCTTACGTCAACGAGTCGCTCAACTTAAGGGGGCAGATGCCAATATTAT
TACGACGTTATGCCACCAATTACCATTGATGCCAGGACTTGAATCTATGCTGGCTGAACTTAAATCCCATGGTTGGCGTT
TAGTGGTGGCATCTGGTGGCTTTACACCTTTTGTGGGGCACTTAAAGCAACTGTTAAATTTAGATGCGGCCTTTGCTAAT
GAGTTAGTGATTACTGACGCTAAACTGGCGGGCACAGTGACGGGTAAGGTCGTTGATGCACAATATAAGGCTGATGTCGT
AGCGCATTGCAGCGCGCAGTGGAATATCCCTCGGGGACAAAGAGTGGCTATTGGTGATGGTGCCAATGATATTCCTATGG
TCAAAGCGGCAGATTTTGGCATTGCATTCCATGCTAAACCTAAGTTAGCTGCAGCGGCGGATGCCAATATTCGCCATCTC
GACTTGCGGGTGTTGCCTTACTTGTTACAAAACTAA

Upstream 100 bases:

>100_bases
AAGCCCTTTAAGATATAACACTTTGACCCTTAACATTTAGAGCGCTTACCTAATCATAATGGATTATGAGTAAGCCCGAT
AGTTGGAGAACACGAGTCCT

Downstream 100 bases:

>100_bases
GTTATCCATTTATTGAAATTAATTGATATAAAAACAGGGGTTAGAGTAATGACTCTTGTTTTTTCAATGTGAACTGGTAG
TTTAGTTCTACTTAATAAAC

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MESLNQDALFLWLATNPSPRFEYQGHLFGAYQESDTPPSGTLVRVRIIYQEISAQKSLAEWLIALASTLKLPHVYIASIK
RQVALHCIELALPLELSSDRVTMFPYDLAELHVFNTDLPKLSVPGLLVMDMDSTAIQIECIDELAAMAGVGEQVAAITER
AMQGELDFEQSLRQRVAQLKGADANIITTLCHQLPLMPGLESMLAELKSHGWRLVVASGGFTPFVGHLKQLLNLDAAFAN
ELVITDAKLAGTVTGKVVDAQYKADVVAHCSAQWNIPRGQRVAIGDGANDIPMVKAADFGIAFHAKPKLAAAADANIRHL
DLRVLPYLLQN

Sequences:

>Translated_331_residues
MESLNQDALFLWLATNPSPRFEYQGHLFGAYQESDTPPSGTLVRVRIIYQEISAQKSLAEWLIALASTLKLPHVYIASIK
RQVALHCIELALPLELSSDRVTMFPYDLAELHVFNTDLPKLSVPGLLVMDMDSTAIQIECIDELAAMAGVGEQVAAITER
AMQGELDFEQSLRQRVAQLKGADANIITTLCHQLPLMPGLESMLAELKSHGWRLVVASGGFTPFVGHLKQLLNLDAAFAN
ELVITDAKLAGTVTGKVVDAQYKADVVAHCSAQWNIPRGQRVAIGDGANDIPMVKAADFGIAFHAKPKLAAAADANIRHL
DLRVLPYLLQN
>Mature_331_residues
MESLNQDALFLWLATNPSPRFEYQGHLFGAYQESDTPPSGTLVRVRIIYQEISAQKSLAEWLIALASTLKLPHVYIASIK
RQVALHCIELALPLELSSDRVTMFPYDLAELHVFNTDLPKLSVPGLLVMDMDSTAIQIECIDELAAMAGVGEQVAAITER
AMQGELDFEQSLRQRVAQLKGADANIITTLCHQLPLMPGLESMLAELKSHGWRLVVASGGFTPFVGHLKQLLNLDAAFAN
ELVITDAKLAGTVTGKVVDAQYKADVVAHCSAQWNIPRGQRVAIGDGANDIPMVKAADFGIAFHAKPKLAAAADANIRHL
DLRVLPYLLQN

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=182, Percent_Identity=31.3186813186813, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1790849, Length=205, Percent_Identity=59.5121951219512, Blast_Score=252, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI115534454, Length=186, Percent_Identity=30.6451612903226, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534456, Length=186, Percent_Identity=31.1827956989247, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321647, Length=206, Percent_Identity=41.2621359223301, Blast_Score=147, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 36127; Mature: 36127

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLNQDALFLWLATNPSPRFEYQGHLFGAYQESDTPPSGTLVRVRIIYQEISAQKSLAE
CCCCCCCEEEEEEECCCCCCCEECCCEEEEECCCCCCCCCCEEEEEEEHHHHHHHHHHHH
WLIALASTLKLPHVYIASIKRQVALHCIELALPLELSSDRVTMFPYDLAELHVFNTDLPK
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECEEECCCEEEEEECCCEEEEEECCCCCC
LSVPGLLVMDMDSTAIQIECIDELAAMAGVGEQVAAITERAMQGELDFEQSLRQRVAQLK
CCCCCEEEEECCCCEEEEEEHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
GADANIITTLCHQLPLMPGLESMLAELKSHGWRLVVASGGFTPFVGHLKQLLNLDAAFAN
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCHHHHCC
ELVITDAKLAGTVTGKVVDAQYKADVVAHCSAQWNIPRGQRVAIGDGANDIPMVKAADFG
CEEEECCHHCCEEECEEEECHHHCCEEEECCCCCCCCCCCEEEECCCCCCCCEEEEECCC
IAFHAKPKLAAAADANIRHLDLRVLPYLLQN
EEEECCCCEEECCCCCEEEEHHHHHHHHHCC
>Mature Secondary Structure
MESLNQDALFLWLATNPSPRFEYQGHLFGAYQESDTPPSGTLVRVRIIYQEISAQKSLAE
CCCCCCCEEEEEEECCCCCCCEECCCEEEEECCCCCCCCCCEEEEEEEHHHHHHHHHHHH
WLIALASTLKLPHVYIASIKRQVALHCIELALPLELSSDRVTMFPYDLAELHVFNTDLPK
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECEEECCCEEEEEECCCEEEEEECCCCCC
LSVPGLLVMDMDSTAIQIECIDELAAMAGVGEQVAAITERAMQGELDFEQSLRQRVAQLK
CCCCCEEEEECCCCEEEEEEHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
GADANIITTLCHQLPLMPGLESMLAELKSHGWRLVVASGGFTPFVGHLKQLLNLDAAFAN
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCHHHHCC
ELVITDAKLAGTVTGKVVDAQYKADVVAHCSAQWNIPRGQRVAIGDGANDIPMVKAADFG
CEEEECCHHCCEEECEEEECHHHCCEEEECCCCCCCCCCCEEEECCCCCCCCEEEEECCC
IAFHAKPKLAAAADANIRHLDLRVLPYLLQN
EEEECCCCEEECCCCCEEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]