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The map label for this gene is deoD

Identifier: 120598015

GI number: 120598015

Start: 1343387

End: 1344097

Strand: Direct

Name: deoD

Synonym: Sputw3181_1192

Alternate gene names: 120598015

Gene position: 1343387-1344097 (Clockwise)

Preceding gene: 120598014

Following gene: 120598017

Centisome position: 28.53

GC content: 44.16

Gene sequence:

>711_bases
ATGGCAACACCACACATTAATGCTGTAGAGGGCGCATTCGCTGAGACAGTTTTGTTTCCTGGCGATCCATTACGTGCAAA
ATATATTGCTGAAACATTCTTAGAAAATGTTGAGCAAGTGACTGATGTTCGAAACATGCTAGGTTTTACTGGTACCTACA
AAGGTAAGCGTATTTCTGTCATGGGTTCAGGCATGGGGATTCCTTCATGCTCTATCTATGCAACTGAATTGATTCGTGAT
TATGGCGTTAAAAACCTGATCCGAGTGGGTACTTGCGGCGCGATCAGCACTGACGTTAAAGTACGCGATGTGATCATCGG
TATGGGCGCATGTACTGATTCACAAGTAAACCGTTTACGTTTTAAAGGTCAAGATTTTGCTGCTATTGCTAACTATGAGC
TGATGAATGCGGTTATCGAGTCAGCTAAAGTCAAAGGCACTAAAATCCGCGTAGGTAATATTTTCTCTGCTGATCTGTTC
TACACTCCTGAGCCACAAATGTTCGATGTGATGGAAAAGATGGGCGTATTAGGCGTAGAGATGGAAGCCGCTGGTTTATA
CGGCGTTGCTCATGAGTTTGGTGCGCGCGCCCTGTGTGTTGTGACTGTATCAGATCATATCCGCACTGGTGAAAAGACGT
CTGCAGAAGAACGTCAAACTACATTCAATGACATGATCATCATGACGTTAGAAGCGGCGATTACACTGTAA

Upstream 100 bases:

>100_bases
TTTATCTAATTACACATACAAGATATCGATTTGGCGGCTGACATTGAGTCGCCAGTAAACAAAGACTTAAGTCTTAATAA
AATAAACAGGGGTTATTTCG

Downstream 100 bases:

>100_bases
ATTTTACTTTGTAAGAATGTGCTAATAAAAAGGGTTCGCATTGCGAACCCTTTTTTATGCCAACTTTTAGCCGCTTTCTA
TTCGACTTTATTATTAATAG

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP 2 [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MATPHINAVEGAFAETVLFPGDPLRAKYIAETFLENVEQVTDVRNMLGFTGTYKGKRISVMGSGMGIPSCSIYATELIRD
YGVKNLIRVGTCGAISTDVKVRDVIIGMGACTDSQVNRLRFKGQDFAAIANYELMNAVIESAKVKGTKIRVGNIFSADLF
YTPEPQMFDVMEKMGVLGVEMEAAGLYGVAHEFGARALCVVTVSDHIRTGEKTSAEERQTTFNDMIIMTLEAAITL

Sequences:

>Translated_236_residues
MATPHINAVEGAFAETVLFPGDPLRAKYIAETFLENVEQVTDVRNMLGFTGTYKGKRISVMGSGMGIPSCSIYATELIRD
YGVKNLIRVGTCGAISTDVKVRDVIIGMGACTDSQVNRLRFKGQDFAAIANYELMNAVIESAKVKGTKIRVGNIFSADLF
YTPEPQMFDVMEKMGVLGVEMEAAGLYGVAHEFGARALCVVTVSDHIRTGEKTSAEERQTTFNDMIIMTLEAAITL
>Mature_235_residues
ATPHINAVEGAFAETVLFPGDPLRAKYIAETFLENVEQVTDVRNMLGFTGTYKGKRISVMGSGMGIPSCSIYATELIRDY
GVKNLIRVGTCGAISTDVKVRDVIIGMGACTDSQVNRLRFKGQDFAAIANYELMNAVIESAKVKGTKIRVGNIFSADLFY
TPEPQMFDVMEKMGVLGVEMEAAGLYGVAHEFGARALCVVTVSDHIRTGEKTSAEERQTTFNDMIIMTLEAAITL

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790844, Length=234, Percent_Identity=69.2307692307692, Blast_Score=348, Evalue=2e-97,
Organism=Escherichia coli, GI1790265, Length=242, Percent_Identity=29.3388429752066, Blast_Score=88, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.1 [H]

Molecular weight: Translated: 25657; Mature: 25526

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPHINAVEGAFAETVLFPGDPLRAKYIAETFLENVEQVTDVRNMLGFTGTYKGKRISV
CCCCCCCHHHCHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
MGSGMGIPSCSIYATELIRDYGVKNLIRVGTCGAISTDVKVRDVIIGMGACTDSQVNRLR
EECCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCHHHHHHE
FKGQDFAAIANYELMNAVIESAKVKGTKIRVGNIFSADLFYTPEPQMFDVMEKMGVLGVE
ECCCCEEHHHHHHHHHHHHHHHHCCCCEEEECCEEEECEEECCCCHHHHHHHHCCCEEEE
MEAAGLYGVAHEFGARALCVVTVSDHIRTGEKTSAEERQTTFNDMIIMTLEAAITL
EHHCCHHHHHHHHCCCEEEEEEECCHHCCCCCCCHHHHHHHHHHEEEEEEEEHHCC
>Mature Secondary Structure 
ATPHINAVEGAFAETVLFPGDPLRAKYIAETFLENVEQVTDVRNMLGFTGTYKGKRISV
CCCCCCHHHCHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
MGSGMGIPSCSIYATELIRDYGVKNLIRVGTCGAISTDVKVRDVIIGMGACTDSQVNRLR
EECCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCHHHHHHE
FKGQDFAAIANYELMNAVIESAKVKGTKIRVGNIFSADLFYTPEPQMFDVMEKMGVLGVE
ECCCCEEHHHHHHHHHHHHHHHHCCCCEEEECCEEEECEEECCCCHHHHHHHHCCCEEEE
MEAAGLYGVAHEFGARALCVVTVSDHIRTGEKTSAEERQTTFNDMIIMTLEAAITL
EHHCCHHHHHHHHCCCEEEEEEECCHHCCCCCCCHHHHHHHHHHEEEEEEEEHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]