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The map label for this gene is dsbC [H]

Identifier: 120597962

GI number: 120597962

Start: 1287626

End: 1288318

Strand: Direct

Name: dsbC [H]

Synonym: Sputw3181_1139

Alternate gene names: 120597962

Gene position: 1287626-1288318 (Clockwise)

Preceding gene: 120597961

Following gene: 120597963

Centisome position: 27.35

GC content: 50.51

Gene sequence:

>693_bases
ATGCGAAAACTATCTCCAATTATTCTGGCGCTTGCGCTGTCTCCATTGGTTCAAGCTGAACCTGTGTCTGAAGTGTCGCC
CGTTGGCAAAATTGACGGCATGGTTTCTTTACCTGTCACGGGTATGAAAGCGGTCGAAAGCAATGGCCGTATTGTTTTCA
TGTCAGACAGTGGCCGGTTCGTCATTGATGGCACGCTCTATGATGCCTGGTCCAAAAAGCCGCTTACCAGTCTTGAAGAA
ATTCGTGAAGCGGGGAACACGCTGGACTTAAGTCGTCTTGGCTTAAAAATGGATGATTTGAACCCACTGACGCTGGGCGA
AGGCAAAAAGAAAGTGGTGGTCTTTGTTGATCCACGATGCCCGCACTGCCATGAGCTTTTGAAACAAGCTTTACCGCTAA
CCAAAGAATACACCTTCCAAATACTCCCTGTGCCAGTGCTTGGTCCTGATTCAGAGCGTCAGGTTCGCCAGCTTGGCTGT
GCGCGTGACAAGAAAGCGGCCACCGATGCATTGCTCAATGGCCGGATTGGTAACCTAGAACAGGATGATGCCTGCAACTT
AGAGCCAATGCAGCGTACCTTGGTGACGGCTCAAATCCTGGGCATTCAAGGTGTGCCTTTCATCGTCGCCAATGATGGTC
GCATCAGTCGAGGCCGTCCTTATGATCTTTCTGCTTGGTTGGAGGGGCGTTAA

Upstream 100 bases:

>100_bases
GCTATTTAGTAAGGTATTCAATTCTTCAATCTATCTAACCGAGTCCACATAGGACAACTGCATAGACTGGAGCCTCGATT
TACATTAACGAGGACTCCTC

Downstream 100 bases:

>100_bases
TGAAAGCCTCTCTGTATTCAGGGCAACGCGCTTCAGAGCTGTTGCCAGTATTGGCCTATTCAGACGATGAGCAACTGTTT
TTCATGGAAGACCAGAGTGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MRKLSPIILALALSPLVQAEPVSEVSPVGKIDGMVSLPVTGMKAVESNGRIVFMSDSGRFVIDGTLYDAWSKKPLTSLEE
IREAGNTLDLSRLGLKMDDLNPLTLGEGKKKVVVFVDPRCPHCHELLKQALPLTKEYTFQILPVPVLGPDSERQVRQLGC
ARDKKAATDALLNGRIGNLEQDDACNLEPMQRTLVTAQILGIQGVPFIVANDGRISRGRPYDLSAWLEGR

Sequences:

>Translated_230_residues
MRKLSPIILALALSPLVQAEPVSEVSPVGKIDGMVSLPVTGMKAVESNGRIVFMSDSGRFVIDGTLYDAWSKKPLTSLEE
IREAGNTLDLSRLGLKMDDLNPLTLGEGKKKVVVFVDPRCPHCHELLKQALPLTKEYTFQILPVPVLGPDSERQVRQLGC
ARDKKAATDALLNGRIGNLEQDDACNLEPMQRTLVTAQILGIQGVPFIVANDGRISRGRPYDLSAWLEGR
>Mature_230_residues
MRKLSPIILALALSPLVQAEPVSEVSPVGKIDGMVSLPVTGMKAVESNGRIVFMSDSGRFVIDGTLYDAWSKKPLTSLEE
IREAGNTLDLSRLGLKMDDLNPLTLGEGKKKVVVFVDPRCPHCHELLKQALPLTKEYTFQILPVPVLGPDSERQVRQLGC
ARDKKAATDALLNGRIGNLEQDDACNLEPMQRTLVTAQILGIQGVPFIVANDGRISRGRPYDLSAWLEGR

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by a yet uncharacterized protein. Also acts as a disulfide isomerase [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=198, Percent_Identity=26.2626262626263, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 25140; Mature: 25140

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLSPIILALALSPLVQAEPVSEVSPVGKIDGMVSLPVTGMKAVESNGRIVFMSDSGRF
CCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCCEEECCCCCHHEECCCCEEEEEECCCCE
VIDGTLYDAWSKKPLTSLEEIREAGNTLDLSRLGLKMDDLNPLTLGEGKKKVVVFVDPRC
EEEEEEECCCCCCCCHHHHHHHHCCCEEEHHHHCCEECCCCCEEECCCCEEEEEEECCCC
PHCHELLKQALPLTKEYTFQILPVPVLGPDSERQVRQLGCARDKKAATDALLNGRIGNLE
CHHHHHHHHHCCCCCCCEEEEEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCCC
QDDACNLEPMQRTLVTAQILGIQGVPFIVANDGRISRGRPYDLSAWLEGR
CCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCEEECCC
>Mature Secondary Structure
MRKLSPIILALALSPLVQAEPVSEVSPVGKIDGMVSLPVTGMKAVESNGRIVFMSDSGRF
CCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCCEEECCCCCHHEECCCCEEEEEECCCCE
VIDGTLYDAWSKKPLTSLEEIREAGNTLDLSRLGLKMDDLNPLTLGEGKKKVVVFVDPRC
EEEEEEECCCCCCCCHHHHHHHHCCCEEEHHHHCCEECCCCCEEECCCCEEEEEEECCCC
PHCHELLKQALPLTKEYTFQILPVPVLGPDSERQVRQLGCARDKKAATDALLNGRIGNLE
CHHHHHHHHHCCCCCCCEEEEEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCCC
QDDACNLEPMQRTLVTAQILGIQGVPFIVANDGRISRGRPYDLSAWLEGR
CCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]