Click here to switch to the map view.

The map label for this gene is hmrR2 [H]

Identifier: 120597941

GI number: 120597941

Start: 1261269

End: 1261733

Strand: Direct

Name: hmrR2 [H]

Synonym: Sputw3181_1111

Alternate gene names: 120597941

Gene position: 1261269-1261733 (Clockwise)

Preceding gene: 120597940

Following gene: 120597944

Centisome position: 26.79

GC content: 46.02

Gene sequence:

>465_bases
ATGAATATCGGAGAAGCATCGCGTAAATCAGGAATATCCACCAAGATGATTCGTTATTACGAGCAAATTGGATTAATCCC
TGCCTCCGAGCGTACGGAGTCAGGTTATCGTAAGTATGCTCTCAATGATGTTCATAGATTGGTTTTTATTCGTAGTGCCC
GAGATCTCGGGTTCTCTCTGGAAGATATAGAAGGCTTGCTTACGTTATGGAATGACAAATCTCGCCAGAGCATTGATGTT
AAACGCCTGGCTCAGGAGAACATTGCTGACTTAGAACGACGTATGGAAAGTATACGTCAAATGACTGAGAAACTACGAGT
TTTAATCCGGAGTTGTGCTGGGGATGAGCGGTCAGAATGTCCTATTCTTAGGACATTAACCAATGCTTCGGGCAAAGCCC
GCACCGTAAACCGAGGAGGAGCGGTACAGCGCCGCTCTGGAGATAAGCTGAGCGGCAAAATGTAG

Upstream 100 bases:

>100_bases
AGCGTGTTCGTTCTGGGAAACTCATTGCGTCTGCGTCGGTTCCAGCCTCCTTTGGTTGAGGACGCTGAGCATTAACGCTG
AGCATTAACAAGGTGGGCTT

Downstream 100 bases:

>100_bases
TACTTTAAATTGGCCCATAATGGTGTAAGACTACGCAGTTTTAACACCATCACATTTTTTTCATTTTAAACAAGCGCGTG
GCATCACTAATGCCCCCCTA

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MNIGEASRKSGISTKMIRYYEQIGLIPASERTESGYRKYALNDVHRLVFIRSARDLGFSLEDIEGLLTLWNDKSRQSIDV
KRLAQENIADLERRMESIRQMTEKLRVLIRSCAGDERSECPILRTLTNASGKARTVNRGGAVQRRSGDKLSGKM

Sequences:

>Translated_154_residues
MNIGEASRKSGISTKMIRYYEQIGLIPASERTESGYRKYALNDVHRLVFIRSARDLGFSLEDIEGLLTLWNDKSRQSIDV
KRLAQENIADLERRMESIRQMTEKLRVLIRSCAGDERSECPILRTLTNASGKARTVNRGGAVQRRSGDKLSGKM
>Mature_154_residues
MNIGEASRKSGISTKMIRYYEQIGLIPASERTESGYRKYALNDVHRLVFIRSARDLGFSLEDIEGLLTLWNDKSRQSIDV
KRLAQENIADLERRMESIRQMTEKLRVLIRSCAGDERSECPILRTLTNASGKARTVNRGGAVQRRSGDKLSGKM

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=127, Percent_Identity=39.3700787401575, Blast_Score=115, Evalue=1e-27,
Organism=Escherichia coli, GI1789687, Length=133, Percent_Identity=37.593984962406, Blast_Score=81, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 17477; Mature: 17477

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGEASRKSGISTKMIRYYEQIGLIPASERTESGYRKYALNDVHRLVFIRSARDLGFSL
CCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EDIEGLLTLWNDKSRQSIDVKRLAQENIADLERRMESIRQMTEKLRVLIRSCAGDERSEC
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PILRTLTNASGKARTVNRGGAVQRRSGDKLSGKM
CHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNIGEASRKSGISTKMIRYYEQIGLIPASERTESGYRKYALNDVHRLVFIRSARDLGFSL
CCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EDIEGLLTLWNDKSRQSIDVKRLAQENIADLERRMESIRQMTEKLRVLIRSCAGDERSEC
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PILRTLTNASGKARTVNRGGAVQRRSGDKLSGKM
CHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]