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The map label for this gene is nlpI [H]

Identifier: 120597906

GI number: 120597906

Start: 1224492

End: 1225397

Strand: Direct

Name: nlpI [H]

Synonym: Sputw3181_1076

Alternate gene names: 120597906

Gene position: 1224492-1225397 (Clockwise)

Preceding gene: 120597905

Following gene: 120597911

Centisome position: 26.01

GC content: 41.5

Gene sequence:

>906_bases
ATGAGTCTTAAAATTAGAACCGCTGTTGTTGCTGTGCTGGCGGGTGCCAGCCTGATGTTGGCTGGATGTGCGACGACCAC
TCAGTCCCCTTTAGATAACCACAATGATCTTGAAGGCAAGTTAGTCGTAGCGCCTGTGATGCCTGACTATAAAGTCGAGG
TCACACTCGCTAAGCTTAATGAGATTTTATCTGCCGTCGAACTGACAAATGAACAGAGAGCCAGATTTCATTATGATCGC
GGCGTAATATACGACAGTGTAGGTTTAAGGCTATTGGCGCGTATCGATTTTATGCAAGCACTTAAACTGCAGCCAGATCT
TGCTGACGCGTATAATTTTCTTGGGATTTATTATACCCAAGAGGGCGAGTATGACAGCGCCTATGAAGCTTTCGATGGCG
TATTGGAACTTGCTCCTAATTACGATTATGCCTATCTAAACCGTGGGATAGCACTTTACTATGGCGATCGAAATGCGCTG
GCCATTAAAGATATGCAAGCCTTTTATGCTGGTGATAATAAAGACGGTTATCGTGCATTGTGGTTATATTTGATAGAGTC
CAAAGATAATCACGAACAAGCCAAACAGCGGTTATTAGAAAATCGTAAGAATCTTGATAACGGAGTATGGTCAACGGTTA
TTGTCGATTATTATTTAGGACACAAGCGCCGTGATGATGTGTTTAATGCAGCCAAAGAAGGTTTAACTCATCCAAAAGAA
TATGCAGAGCGTTTATGTGAAGCGTATTTTTATCTTGCAAAAATGGCGATAGAGCAAAAGCAATATCAAGATGCAGCAAA
TTACTTACGGCTTACACTCGCGACTAATATCTATGATTTTGTTGAACACAGATATGCCCGTATTGAGCTAGCAAAAGTTA
AAGGTTTGCTCGAAGACACAAAATAA

Upstream 100 bases:

>100_bases
TAATTGTGATTAATGCTATTCGTTAATAGAAGTCCTCTGGTGGGATTGCTATGATGAATACTCTTCTGCATGTGTTGGGA
ATCTAAAAAGGTAGAAATGG

Downstream 100 bases:

>100_bases
CCTCCTCTGCCCGGGCTCATCTCGGGCTTTGCCTAGCCAAGTGAGAACTGAGGCGCTATAATTTGCGCCTTTTTAGCGAT
ACTAGTGCATAGGTTAATAT

Product: lipoprotein NlpI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSLKIRTAVVAVLAGASLMLAGCATTTQSPLDNHNDLEGKLVVAPVMPDYKVEVTLAKLNEILSAVELTNEQRARFHYDR
GVIYDSVGLRLLARIDFMQALKLQPDLADAYNFLGIYYTQEGEYDSAYEAFDGVLELAPNYDYAYLNRGIALYYGDRNAL
AIKDMQAFYAGDNKDGYRALWLYLIESKDNHEQAKQRLLENRKNLDNGVWSTVIVDYYLGHKRRDDVFNAAKEGLTHPKE
YAERLCEAYFYLAKMAIEQKQYQDAANYLRLTLATNIYDFVEHRYARIELAKVKGLLEDTK

Sequences:

>Translated_301_residues
MSLKIRTAVVAVLAGASLMLAGCATTTQSPLDNHNDLEGKLVVAPVMPDYKVEVTLAKLNEILSAVELTNEQRARFHYDR
GVIYDSVGLRLLARIDFMQALKLQPDLADAYNFLGIYYTQEGEYDSAYEAFDGVLELAPNYDYAYLNRGIALYYGDRNAL
AIKDMQAFYAGDNKDGYRALWLYLIESKDNHEQAKQRLLENRKNLDNGVWSTVIVDYYLGHKRRDDVFNAAKEGLTHPKE
YAERLCEAYFYLAKMAIEQKQYQDAANYLRLTLATNIYDFVEHRYARIELAKVKGLLEDTK
>Mature_300_residues
SLKIRTAVVAVLAGASLMLAGCATTTQSPLDNHNDLEGKLVVAPVMPDYKVEVTLAKLNEILSAVELTNEQRARFHYDRG
VIYDSVGLRLLARIDFMQALKLQPDLADAYNFLGIYYTQEGEYDSAYEAFDGVLELAPNYDYAYLNRGIALYYGDRNALA
IKDMQAFYAGDNKDGYRALWLYLIESKDNHEQAKQRLLENRKNLDNGVWSTVIVDYYLGHKRRDDVFNAAKEGLTHPKEY
AERLCEAYFYLAKMAIEQKQYQDAANYLRLTLATNIYDFVEHRYARIELAKVKGLLEDTK

Specific function: May be involved in cell division. Overexpression of nlpI results in the loss of the rod morphology and the formation of single prolate ellipsoids and pairs of prolate ellipsoids joined by partial constrictions [H]

COG id: COG4785

COG function: function code R; Lipoprotein NlpI, contains TPR repeats

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1789554, Length=280, Percent_Identity=43.5714285714286, Blast_Score=237, Evalue=7e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 34410; Mature: 34279

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKIRTAVVAVLAGASLMLAGCATTTQSPLDNHNDLEGKLVVAPVMPDYKVEVTLAKLN
CCEEHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEHHHHH
EILSAVELTNEQRARFHYDRGVIYDSVGLRLLARIDFMQALKLQPDLADAYNFLGIYYTQ
HHHHHHHHCCHHHHHEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEEEEEEC
EGEYDSAYEAFDGVLELAPNYDYAYLNRGIALYYGDRNALAIKDMQAFYAGDNKDGYRAL
CCCCCHHHHHHHHHHHHCCCCCCHHHCCCEEEEECCCCEEEEHHHHHHHCCCCCCCCEEE
WLYLIESKDNHEQAKQRLLENRKNLDNGVWSTVIVDYYLGHKRRDDVFNAAKEGLTHPKE
EEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHH
YAERLCEAYFYLAKMAIEQKQYQDAANYLRLTLATNIYDFVEHRYARIELAKVKGLLEDT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
K
C
>Mature Secondary Structure 
SLKIRTAVVAVLAGASLMLAGCATTTQSPLDNHNDLEGKLVVAPVMPDYKVEVTLAKLN
CEEHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEHHHHH
EILSAVELTNEQRARFHYDRGVIYDSVGLRLLARIDFMQALKLQPDLADAYNFLGIYYTQ
HHHHHHHHCCHHHHHEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEEEEEEC
EGEYDSAYEAFDGVLELAPNYDYAYLNRGIALYYGDRNALAIKDMQAFYAGDNKDGYRAL
CCCCCHHHHHHHHHHHHCCCCCCHHHCCCEEEEECCCCEEEEHHHHHHHCCCCCCCCEEE
WLYLIESKDNHEQAKQRLLENRKNLDNGVWSTVIVDYYLGHKRRDDVFNAAKEGLTHPKE
EEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHH
YAERLCEAYFYLAKMAIEQKQYQDAANYLRLTLATNIYDFVEHRYARIELAKVKGLLEDT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]