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The map label for this gene is cobT

Identifier: 120597816

GI number: 120597816

Start: 1125147

End: 1126199

Strand: Direct

Name: cobT

Synonym: Sputw3181_0986

Alternate gene names: 120597816

Gene position: 1125147-1126199 (Clockwise)

Preceding gene: 120597815

Following gene: 120597817

Centisome position: 23.9

GC content: 48.15

Gene sequence:

>1053_bases
ATGTCTCAATCAGCCGTGTCGTTTCAAATTAACCCTGTGAGCAAAGTACAAGAACAGTCGATTCAACAGAAAATAAATCT
TAAGACTAAGCCGCTTGGCGCCCTCGGGCAGCTCGAATCCTTAGCATTACAAATAGCTCGCATACAGGGTGCTGATCAGC
CATATATAGCGAATCCCACCATGCTGGTGTTTGCGGGTGACCATGGCATTGCAGCAGAAGGCGTTTCCATTGCCCCTAGT
GAAGTGACGCGCCAAATGGTGCAAAACTTTGCCCATGGCGGTGCGGCAATTAATGTTTTTTGTCGGCAAGTTGGCTTTAA
GCTCGAAGTGATCGATTGCGGTATTTTAACGCCTATCGAAGGGGTTAAAGGCATTATTGATCAACGTCTTGGCGCTGGAA
CTGGCGCTATTCATTTAGAGCCTGCCATGGCGCTGGAAACCGTCGATAAAGGCTTTGCGATGGCGCGTGATTTGATTGAA
CGCCACCACCAAACGGGCTGTAATCTGGTGGCCTTTGGCGAGATGGGCATAGGCAATACCTCTGCCGCATCTGCGATTAT
GGCGGCGATAATGCAGCTCGATGTGATTGATTGTGTTGGCCGTGGTACTGGCATTAATCAAGAAACCTTAGCGCGAAAAT
TGATGCTGATTGAGCTAGCGTTATTGCTACATCAAAGTGCGTTAACTGGACCAAAAGAAGTGTTGGCGTGTTTAGGTGGT
TTTGAAATTGTGCAGATGACAGGCGCTATGTTAGCCGCCGCCGAGCGTAACATGCTGGTGGTTGTGGATGGTTTTATCGC
GACTGCCGCTGCATTAGTCGCAGTAACAATAGCGCCTAATGTGCGCGACTATTTGATTTTTGCCCATCAATCAGAAGAGC
AAGGCCATCTGCGAATGTTAGAATTTTTGCAGGCTAAACCTTTGCTATCGCTTGGCCTAAGATTAGGCGAAGGCACTGGT
GCAGCCTTGGCTCTACCGCTTATCCAAGCAGCAGTAAATTTTTACAATCAAATGGCGAGTTTTAGTGATGCGGGGATTGA
GGCTGTTGTATGA

Upstream 100 bases:

>100_bases
GCGGCGAAAAGTAACCCGTTAATTTAATGCTTACGACCTATGGAAAAGAGTCATGGAATGCATCGTAGTGATTAAATTTG
GATTAGCAAGTGGAGTGTGA

Downstream 100 bases:

>100_bases
TATGCATCAGCTAAGCTGTTTATTTTACTTATTTAAAATAATAACTTTTTAGCCAACCGTTTTAATTTTAAACCTTGCAG
CAAGTGTGGATTCACTAAGG

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSQSAVSFQINPVSKVQEQSIQQKINLKTKPLGALGQLESLALQIARIQGADQPYIANPTMLVFAGDHGIAAEGVSIAPS
EVTRQMVQNFAHGGAAINVFCRQVGFKLEVIDCGILTPIEGVKGIIDQRLGAGTGAIHLEPAMALETVDKGFAMARDLIE
RHHQTGCNLVAFGEMGIGNTSAASAIMAAIMQLDVIDCVGRGTGINQETLARKLMLIELALLLHQSALTGPKEVLACLGG
FEIVQMTGAMLAAAERNMLVVVDGFIATAAALVAVTIAPNVRDYLIFAHQSEEQGHLRMLEFLQAKPLLSLGLRLGEGTG
AALALPLIQAAVNFYNQMASFSDAGIEAVV

Sequences:

>Translated_350_residues
MSQSAVSFQINPVSKVQEQSIQQKINLKTKPLGALGQLESLALQIARIQGADQPYIANPTMLVFAGDHGIAAEGVSIAPS
EVTRQMVQNFAHGGAAINVFCRQVGFKLEVIDCGILTPIEGVKGIIDQRLGAGTGAIHLEPAMALETVDKGFAMARDLIE
RHHQTGCNLVAFGEMGIGNTSAASAIMAAIMQLDVIDCVGRGTGINQETLARKLMLIELALLLHQSALTGPKEVLACLGG
FEIVQMTGAMLAAAERNMLVVVDGFIATAAALVAVTIAPNVRDYLIFAHQSEEQGHLRMLEFLQAKPLLSLGLRLGEGTG
AALALPLIQAAVNFYNQMASFSDAGIEAVV
>Mature_349_residues
SQSAVSFQINPVSKVQEQSIQQKINLKTKPLGALGQLESLALQIARIQGADQPYIANPTMLVFAGDHGIAAEGVSIAPSE
VTRQMVQNFAHGGAAINVFCRQVGFKLEVIDCGILTPIEGVKGIIDQRLGAGTGAIHLEPAMALETVDKGFAMARDLIER
HHQTGCNLVAFGEMGIGNTSAASAIMAAIMQLDVIDCVGRGTGINQETLARKLMLIELALLLHQSALTGPKEVLACLGGF
EIVQMTGAMLAAAERNMLVVVDGFIATAAALVAVTIAPNVRDYLIFAHQSEEQGHLRMLEFLQAKPLLSLGLRLGEGTGA
ALALPLIQAAVNFYNQMASFSDAGIEAVV

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=326, Percent_Identity=37.4233128834356, Blast_Score=207, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 36906; Mature: 36774

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSAVSFQINPVSKVQEQSIQQKINLKTKPLGALGQLESLALQIARIQGADQPYIANPT
CCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCE
MLVFAGDHGIAAEGVSIAPSEVTRQMVQNFAHGGAAINVFCRQVGFKLEVIDCGILTPIE
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEEECCCCCCHH
GVKGIIDQRLGAGTGAIHLEPAMALETVDKGFAMARDLIERHHQTGCNLVAFGEMGIGNT
HHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCH
SAASAIMAAIMQLDVIDCVGRGTGINQETLARKLMLIELALLLHQSALTGPKEVLACLGG
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
FEIVQMTGAMLAAAERNMLVVVDGFIATAAALVAVTIAPNVRDYLIFAHQSEEQGHLRML
HHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHEECCCCEEEEEEEECCCCCCHHHHH
EFLQAKPLLSLGLRLGEGTGAALALPLIQAAVNFYNQMASFSDAGIEAVV
HHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECC
>Mature Secondary Structure 
SQSAVSFQINPVSKVQEQSIQQKINLKTKPLGALGQLESLALQIARIQGADQPYIANPT
CCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCE
MLVFAGDHGIAAEGVSIAPSEVTRQMVQNFAHGGAAINVFCRQVGFKLEVIDCGILTPIE
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEEECCCCCCHH
GVKGIIDQRLGAGTGAIHLEPAMALETVDKGFAMARDLIERHHQTGCNLVAFGEMGIGNT
HHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCH
SAASAIMAAIMQLDVIDCVGRGTGINQETLARKLMLIELALLLHQSALTGPKEVLACLGG
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
FEIVQMTGAMLAAAERNMLVVVDGFIATAAALVAVTIAPNVRDYLIFAHQSEEQGHLRML
HHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHEECCCCEEEEEEEECCCCCCHHHHH
EFLQAKPLLSLGLRLGEGTGAALALPLIQAAVNFYNQMASFSDAGIEAVV
HHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA