Click here to switch to the map view.

The map label for this gene is ntrY [H]

Identifier: 120597790

GI number: 120597790

Start: 1093628

End: 1095316

Strand: Direct

Name: ntrY [H]

Synonym: Sputw3181_0960

Alternate gene names: 120597790

Gene position: 1093628-1095316 (Clockwise)

Preceding gene: 120597789

Following gene: 120597791

Centisome position: 23.23

GC content: 44.46

Gene sequence:

>1689_bases
GTGTTAATTCGAACTAAAATTATCATTTATTCAATAGCGTGCTGTGCCTTTGGCGTATTATTGAGCTTTGCCTTGGTGAA
ATATATTTTATCCGAGGCATCAGTTGTTACCACGCCTCAGGCGATTAAAACCCCTGATAATAATGTCGTCTTTGACTTTG
CTGAGCTTGAAAAAAACCTCGCGTCTATCGAACTCGCCCTTAACAATAGTGAGCCATTGCAGCAGGCCGCAGCAATGCAA
GCGCACCAAAGGGCAGAGCAGATTAAGGCTGAACTGCAAAAGCTTGAACAACTTAAACAAGCACAGTTACAGATAAAACT
TTTTACCTTAGAACAGCTTAAAGAAGGGGCATTTAATTCTATGCCTCATATTGTTGAGCCTTTACGTGTCGAGCCACTAT
CCATTTTACCGCCTAAAGCCCCCGTATCCTCTGTTGCGCCCGCCGAGATAGTCGCCAGTGAACCTGCCGCTAGTTTGACC
TTAGGTGAGGGGTTGATGGTGTTATTGTTCGCCTGCTGTGTCTGTGGTTTAGGCATTGCTTGGTTGACTCGACATCTTGG
CCGCAGTTTAGATTCCCTTGAAGTCGGCTTGCTCAATTTTAGTGATAATGATTTTAGTGTGAGTATTCCTGAACATGGTG
AAGGGCAACTCAAAACCTTAGCGCAGTTATTTAATCATAGCGCGGCTAAATTGCGCCAAGAAAGGCAATACATTTATCAA
CGTGAGTTATTGCTGGATAAGGTGATTCAGAGTTCCCCCAATGTGATGTTATTGCTCGATGACCATCAACGGCTCATTTA
CGCCAATGATGCCGCGCGTCACCTATTTCATAAAAAGGGCAGAATGGAAGGCTTGAGCTTAGATGAATTACTGGTGGATT
TGCCCGAGGCATTGGCCTTAGCACTTAAACATGAAAAGAACGGCCTCTTTGCCATGGGCGAAGATGAGATGGAAACTTGG
TATATCAGCCGTGGTCAGTTTTTATTGAATAACCAACAGCATAACTTAATCTTGCTCAAACAGATGACTCGAGAACTCAA
TCGCCAAGAGGTGGCTGTGTGGAAAAAAGTCATCCGCATTATTAGCCATGAACTCAATAACTCCGTCGCGCCCATTGCTT
CTATGGTCAATTCGGGCCGTCTACTCACTCAAGATATAGATGATCCTAGGTTAACCTTAATTTTCGATACGATTGAGAAT
CGCACTAATCATTTAAGTCAGTTTATCTTCAACTATGCTCGCTTCGCTAAGTTGCCGCTTCCACAGCGGTGTCAGGTGAG
TTGGGCGCAATTTACCGCCCAGTTAACCCAGCATTATCCCTTTAAACTTAAGGATGATTTGCCTGAGATCGATGGCTATT
TTGACCAAGGACAGATGGAGCAAGTGCTCCTTAATTTACTGAAAAATGCCCATGAATCTGGTTCAAACCCCGAGGACGTC
ACCTTATCGATTCGATATCAAACCTTAGTAGATGGCGCGGGTTTCAGTATTGCGATTGAGGATCGCGGCGCAGGTATGTC
TGGCGAAGTATTAGAGCAGGCGCTATTACCATTTTACTCAACAAAACAATCGGGTACAGGCTTAGGTTTACCTTTGTGTC
GTGAAATTATTGAAGCCCACGATGGCTGTATTAGCATGCATAATCGCAGTGACGGTGGCCTGTTGGTTCGACTATGGTTG
CCACAATAA

Upstream 100 bases:

>100_bases
CAGGCGCTGTATCGGCGAATGGATAAATTTGGTTTAGATAAGTCATAGGCTAAGCGCAGGCGCTAGGTTATAGATGAAGG
CTATCGATTAAGGAATATGA

Downstream 100 bases:

>100_bases
TGCCAGTGTTTTAAATAACACCGCCATACACGTTTAAGGCACATTTTTATTGCCTATTTTCTTCGCTTGTTTAAACACAA
CTCCTATCCTCCGTGGCCGC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MLIRTKIIIYSIACCAFGVLLSFALVKYILSEASVVTTPQAIKTPDNNVVFDFAELEKNLASIELALNNSEPLQQAAAMQ
AHQRAEQIKAELQKLEQLKQAQLQIKLFTLEQLKEGAFNSMPHIVEPLRVEPLSILPPKAPVSSVAPAEIVASEPAASLT
LGEGLMVLLFACCVCGLGIAWLTRHLGRSLDSLEVGLLNFSDNDFSVSIPEHGEGQLKTLAQLFNHSAAKLRQERQYIYQ
RELLLDKVIQSSPNVMLLLDDHQRLIYANDAARHLFHKKGRMEGLSLDELLVDLPEALALALKHEKNGLFAMGEDEMETW
YISRGQFLLNNQQHNLILLKQMTRELNRQEVAVWKKVIRIISHELNNSVAPIASMVNSGRLLTQDIDDPRLTLIFDTIEN
RTNHLSQFIFNYARFAKLPLPQRCQVSWAQFTAQLTQHYPFKLKDDLPEIDGYFDQGQMEQVLLNLLKNAHESGSNPEDV
TLSIRYQTLVDGAGFSIAIEDRGAGMSGEVLEQALLPFYSTKQSGTGLGLPLCREIIEAHDGCISMHNRSDGGLLVRLWL
PQ

Sequences:

>Translated_562_residues
MLIRTKIIIYSIACCAFGVLLSFALVKYILSEASVVTTPQAIKTPDNNVVFDFAELEKNLASIELALNNSEPLQQAAAMQ
AHQRAEQIKAELQKLEQLKQAQLQIKLFTLEQLKEGAFNSMPHIVEPLRVEPLSILPPKAPVSSVAPAEIVASEPAASLT
LGEGLMVLLFACCVCGLGIAWLTRHLGRSLDSLEVGLLNFSDNDFSVSIPEHGEGQLKTLAQLFNHSAAKLRQERQYIYQ
RELLLDKVIQSSPNVMLLLDDHQRLIYANDAARHLFHKKGRMEGLSLDELLVDLPEALALALKHEKNGLFAMGEDEMETW
YISRGQFLLNNQQHNLILLKQMTRELNRQEVAVWKKVIRIISHELNNSVAPIASMVNSGRLLTQDIDDPRLTLIFDTIEN
RTNHLSQFIFNYARFAKLPLPQRCQVSWAQFTAQLTQHYPFKLKDDLPEIDGYFDQGQMEQVLLNLLKNAHESGSNPEDV
TLSIRYQTLVDGAGFSIAIEDRGAGMSGEVLEQALLPFYSTKQSGTGLGLPLCREIIEAHDGCISMHNRSDGGLLVRLWL
PQ
>Mature_562_residues
MLIRTKIIIYSIACCAFGVLLSFALVKYILSEASVVTTPQAIKTPDNNVVFDFAELEKNLASIELALNNSEPLQQAAAMQ
AHQRAEQIKAELQKLEQLKQAQLQIKLFTLEQLKEGAFNSMPHIVEPLRVEPLSILPPKAPVSSVAPAEIVASEPAASLT
LGEGLMVLLFACCVCGLGIAWLTRHLGRSLDSLEVGLLNFSDNDFSVSIPEHGEGQLKTLAQLFNHSAAKLRQERQYIYQ
RELLLDKVIQSSPNVMLLLDDHQRLIYANDAARHLFHKKGRMEGLSLDELLVDLPEALALALKHEKNGLFAMGEDEMETW
YISRGQFLLNNQQHNLILLKQMTRELNRQEVAVWKKVIRIISHELNNSVAPIASMVNSGRLLTQDIDDPRLTLIFDTIEN
RTNHLSQFIFNYARFAKLPLPQRCQVSWAQFTAQLTQHYPFKLKDDLPEIDGYFDQGQMEQVLLNLLKNAHESGSNPEDV
TLSIRYQTLVDGAGFSIAIEDRGAGMSGEVLEQALLPFYSTKQSGTGLGLPLCREIIEAHDGCISMHNRSDGGLLVRLWL
PQ

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790300, Length=328, Percent_Identity=25.9146341463415, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790436, Length=121, Percent_Identity=34.7107438016529, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788549, Length=238, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 62888; Mature: 62888

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIRTKIIIYSIACCAFGVLLSFALVKYILSEASVVTTPQAIKTPDNNVVFDFAELEKNL
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHCCCCCCEEEEHHHHHCCH
ASIELALNNSEPLQQAAAMQAHQRAEQIKAELQKLEQLKQAQLQIKLFTLEQLKEGAFNS
HEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHCCCCCC
MPHIVEPLRVEPLSILPPKAPVSSVAPAEIVASEPAASLTLGEGLMVLLFACCVCGLGIA
CCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEECCCCHHHHHHHHHHHHCCHH
WLTRHLGRSLDSLEVGLLNFSDNDFSVSIPEHGEGQLKTLAQLFNHSAAKLRQERQYIYQ
HHHHHHCCCCCCCEEEEEEECCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
RELLLDKVIQSSPNVMLLLDDHQRLIYANDAARHLFHKKGRMEGLSLDELLVDLPEALAL
HHHHHHHHHHCCCCEEEEEECCCEEEEECHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
ALKHEKNGLFAMGEDEMETWYISRGQFLLNNQQHNLILLKQMTRELNRQEVAVWKKVIRI
HHHHCCCCCEEECCCCHHEEEEECCEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
ISHELNNSVAPIASMVNSGRLLTQDIDDPRLTLIFDTIENRTNHLSQFIFNYARFAKLPL
HHHHHCCCHHHHHHHHHCCCEEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCC
PQRCQVSWAQFTAQLTQHYPFKLKDDLPEIDGYFDQGQMEQVLLNLLKNAHESGSNPEDV
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCE
TLSIRYQTLVDGAGFSIAIEDRGAGMSGEVLEQALLPFYSTKQSGTGLGLPLCREIIEAH
EEEEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHCCHHCCCCCCCCCCHHHHHHHHHHC
DGCISMHNRSDGGLLVRLWLPQ
CCEEEECCCCCCCEEEEEECCC
>Mature Secondary Structure
MLIRTKIIIYSIACCAFGVLLSFALVKYILSEASVVTTPQAIKTPDNNVVFDFAELEKNL
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHCCCCCCEEEEHHHHHCCH
ASIELALNNSEPLQQAAAMQAHQRAEQIKAELQKLEQLKQAQLQIKLFTLEQLKEGAFNS
HEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHCCCCCC
MPHIVEPLRVEPLSILPPKAPVSSVAPAEIVASEPAASLTLGEGLMVLLFACCVCGLGIA
CCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEECCCCHHHHHHHHHHHHCCHH
WLTRHLGRSLDSLEVGLLNFSDNDFSVSIPEHGEGQLKTLAQLFNHSAAKLRQERQYIYQ
HHHHHHCCCCCCCEEEEEEECCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
RELLLDKVIQSSPNVMLLLDDHQRLIYANDAARHLFHKKGRMEGLSLDELLVDLPEALAL
HHHHHHHHHHCCCCEEEEEECCCEEEEECHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
ALKHEKNGLFAMGEDEMETWYISRGQFLLNNQQHNLILLKQMTRELNRQEVAVWKKVIRI
HHHHCCCCCEEECCCCHHEEEEECCEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
ISHELNNSVAPIASMVNSGRLLTQDIDDPRLTLIFDTIENRTNHLSQFIFNYARFAKLPL
HHHHHCCCHHHHHHHHHCCCEEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCC
PQRCQVSWAQFTAQLTQHYPFKLKDDLPEIDGYFDQGQMEQVLLNLLKNAHESGSNPEDV
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCE
TLSIRYQTLVDGAGFSIAIEDRGAGMSGEVLEQALLPFYSTKQSGTGLGLPLCREIIEAH
EEEEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHCCHHCCCCCCCCCCHHHHHHHHHHC
DGCISMHNRSDGGLLVRLWLPQ
CCEEEECCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]