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The map label for this gene is atoC [H]

Identifier: 120597789

GI number: 120597789

Start: 1092118

End: 1093575

Strand: Direct

Name: atoC [H]

Synonym: Sputw3181_0959

Alternate gene names: 120597789

Gene position: 1092118-1093575 (Clockwise)

Preceding gene: 120597788

Following gene: 120597790

Centisome position: 23.2

GC content: 48.08

Gene sequence:

>1458_bases
ATGGATACCATTCTTATCGTCGATGACAATCACGCCATCTGCCAAGCACTGGGTTTAATGCTTGAGTTGAATGGTTATCG
AGTCTTATCTTGCCATACTCCAGAAGAAGCCCTTGGAGTGCTGACGACTCAGGAGGTCGATCTTGTCATTCAAGATATGA
ACTTTACCCGAGATACCACTTCAGGCGAGGAGGGACGACAGCTTTTTTATGCCCTACGTGAACAGCAAGCGGATCTCCCC
ATTATTTTAATGACAGCGTGGACGCAACTCGAAACGGCGGTTGAATTAGTTAAAGCGGGCGCCGCCGATTATATGGGTAA
ACCTTGGGATGATGCTAAAGTACTCAATAGCATCACTAATCTGATTGCGCTCTATAAACTCTCCCGTGCTAACCACCGCT
TGGAGCGGGTGAATCATCAACGGCAAGTGGCGATCGCCGATGCTAATCTCTGCGGTATCGTCTTTGGCAGCGGTGCTATG
CAGCGTTGTATTGACTTAGCCTTGCAATTGGCGCGCTCCGATGTATCTGTGTTGATCACAGGCCCCAATGGTGCGGGAAA
AGACAAACTCGCCGATATTCTCCACGCCAATTCACCCTTAAAAAACAAACCTTTTATCAAGGTCAATGTCGGTGCTTTGC
CGATGGATTTATTAGAAGCCGAGCTGTTTGGTGCCGAGGCTGGCGCTTTTACTGGCGCGACTAAAGCGCGTATTGGTCGT
TTTGAGGCGGCAGACGGCGGCACGCTGTTTCTAGATGAAATCGGTAATTTGCCGTTATCTGGCCAAGTGAAATTATTGCG
GGTGCTACAAACCGGCGAATTTGAACGCTTAGGAAGCCATAAAACACAGAAAGTAAAAGTGCGGGTGATCAGTGCGACCA
ATGCGGATCTGGCCCAAGATATCGCCGAAGGGCGATTCCGTGAGGATTTATTCTACCGCTTAAATGTGATTGAACTGGCA
TTGCCACCGCTGAATCAACGCACCGATGATATTTTACCTTTAGTACAGCATTTTATCGGTAGCGATTTTAGCTTGAGTAA
ACCTGCGCTTCAGGCGTTATTGCACCACCGCTGGCCGGGAAATGTCCGAGAGCTTGAAAACGCCTGTAAGCGAGCCGTAT
TACTAGCACAAGGTCATGTGTTGACGGAAACTGACTTTGGTTTGGCACCTGTTGCGAGAGCCATAAAATCTTCTTCCAGT
GTTTCGGCTGTTTCTGAGCAGCGGCAATTTGATCCTCAGCCTGAAATGGGTGAACAGTACTCTAAGCCCGTTTATGCATC
CGCTTCTATCCCCGCTAATACTGTATTTTCCAATGAATCGGTTGATGTGAGCCGAGAAGAAATCGAAGCTGCACTGAGCT
TGCATAAAGGAGTGATTGCGAGAGTTGCAAAATCCCTTGGACTCAGTCGTCAGGCGCTGTATCGGCGAATGGATAAATTT
GGTTTAGATAAGTCATAG

Upstream 100 bases:

>100_bases
AGGAGATTCAAGCTAGGAAAGGTGCGATAACAATAGGATGTTATTGCACTTTTTGTTACTTTACCGTTAATGGGTTTTAC
TTGGGGCTGAACTGAGAATT

Downstream 100 bases:

>100_bases
GCTAAGCGCAGGCGCTAGGTTATAGATGAAGGCTATCGATTAAGGAATATGAGTGTTAATTCGAACTAAAATTATCATTT
ATTCAATAGCGTGCTGTGCC

Product: two component, sigma54 specific, Fis family transcriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MDTILIVDDNHAICQALGLMLELNGYRVLSCHTPEEALGVLTTQEVDLVIQDMNFTRDTTSGEEGRQLFYALREQQADLP
IILMTAWTQLETAVELVKAGAADYMGKPWDDAKVLNSITNLIALYKLSRANHRLERVNHQRQVAIADANLCGIVFGSGAM
QRCIDLALQLARSDVSVLITGPNGAGKDKLADILHANSPLKNKPFIKVNVGALPMDLLEAELFGAEAGAFTGATKARIGR
FEAADGGTLFLDEIGNLPLSGQVKLLRVLQTGEFERLGSHKTQKVKVRVISATNADLAQDIAEGRFREDLFYRLNVIELA
LPPLNQRTDDILPLVQHFIGSDFSLSKPALQALLHHRWPGNVRELENACKRAVLLAQGHVLTETDFGLAPVARAIKSSSS
VSAVSEQRQFDPQPEMGEQYSKPVYASASIPANTVFSNESVDVSREEIEAALSLHKGVIARVAKSLGLSRQALYRRMDKF
GLDKS

Sequences:

>Translated_485_residues
MDTILIVDDNHAICQALGLMLELNGYRVLSCHTPEEALGVLTTQEVDLVIQDMNFTRDTTSGEEGRQLFYALREQQADLP
IILMTAWTQLETAVELVKAGAADYMGKPWDDAKVLNSITNLIALYKLSRANHRLERVNHQRQVAIADANLCGIVFGSGAM
QRCIDLALQLARSDVSVLITGPNGAGKDKLADILHANSPLKNKPFIKVNVGALPMDLLEAELFGAEAGAFTGATKARIGR
FEAADGGTLFLDEIGNLPLSGQVKLLRVLQTGEFERLGSHKTQKVKVRVISATNADLAQDIAEGRFREDLFYRLNVIELA
LPPLNQRTDDILPLVQHFIGSDFSLSKPALQALLHHRWPGNVRELENACKRAVLLAQGHVLTETDFGLAPVARAIKSSSS
VSAVSEQRQFDPQPEMGEQYSKPVYASASIPANTVFSNESVDVSREEIEAALSLHKGVIARVAKSLGLSRQALYRRMDKF
GLDKS
>Mature_485_residues
MDTILIVDDNHAICQALGLMLELNGYRVLSCHTPEEALGVLTTQEVDLVIQDMNFTRDTTSGEEGRQLFYALREQQADLP
IILMTAWTQLETAVELVKAGAADYMGKPWDDAKVLNSITNLIALYKLSRANHRLERVNHQRQVAIADANLCGIVFGSGAM
QRCIDLALQLARSDVSVLITGPNGAGKDKLADILHANSPLKNKPFIKVNVGALPMDLLEAELFGAEAGAFTGATKARIGR
FEAADGGTLFLDEIGNLPLSGQVKLLRVLQTGEFERLGSHKTQKVKVRVISATNADLAQDIAEGRFREDLFYRLNVIELA
LPPLNQRTDDILPLVQHFIGSDFSLSKPALQALLHHRWPGNVRELENACKRAVLLAQGHVLTETDFGLAPVARAIKSSSS
VSAVSEQRQFDPQPEMGEQYSKPVYASASIPANTVFSNESVDVSREEIEAALSLHKGVIARVAKSLGLSRQALYRRMDKF
GLDKS

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=493, Percent_Identity=38.1338742393509, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1790299, Length=491, Percent_Identity=36.6598778004073, Blast_Score=278, Evalue=5e-76,
Organism=Escherichia coli, GI1790437, Length=485, Percent_Identity=36.2886597938144, Blast_Score=263, Evalue=3e-71,
Organism=Escherichia coli, GI1788905, Length=388, Percent_Identity=39.9484536082474, Blast_Score=252, Evalue=4e-68,
Organism=Escherichia coli, GI87082117, Length=383, Percent_Identity=38.1201044386423, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI1789087, Length=386, Percent_Identity=39.3782383419689, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI87082152, Length=348, Percent_Identity=38.2183908045977, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1789233, Length=334, Percent_Identity=38.9221556886228, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1786524, Length=240, Percent_Identity=47.9166666666667, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI87081872, Length=214, Percent_Identity=47.196261682243, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1787583, Length=363, Percent_Identity=33.6088154269972, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1789828, Length=273, Percent_Identity=33.6996336996337, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87081858, Length=330, Percent_Identity=29.0909090909091, Blast_Score=119, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 53070; Mature: 53070

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTILIVDDNHAICQALGLMLELNGYRVLSCHTPEEALGVLTTQEVDLVIQDMNFTRDTT
CCEEEEEECCHHHHHHHHHHEEECCEEEEEECCCHHHHHHHEECCCEEEEECCCCCCCCC
SGEEGRQLFYALREQQADLPIILMTAWTQLETAVELVKAGAADYMGKPWDDAKVLNSITN
CCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHH
LIALYKLSRANHRLERVNHQRQVAIADANLCGIVFGSGAMQRCIDLALQLARSDVSVLIT
HHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEE
GPNGAGKDKLADILHANSPLKNKPFIKVNVGALPMDLLEAELFGAEAGAFTGATKARIGR
CCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHCCC
FEAADGGTLFLDEIGNLPLSGQVKLLRVLQTGEFERLGSHKTQKVKVRVISATNADLAQD
EECCCCCEEEHHHHCCCCCCCCHHHHHHHHCCCHHHHCCCCCEEEEEEEEECCCCHHHHH
IAEGRFREDLFYRLNVIELALPPLNQRTDDILPLVQHFIGSDFSLSKPALQALLHHRWPG
HHHCHHHHHHHHHHEEHEEECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCC
NVRELENACKRAVLLAQGHVLTETDFGLAPVARAIKSSSSVSAVSEQRQFDPQPEMGEQY
CHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHH
SKPVYASASIPANTVFSNESVDVSREEIEAALSLHKGVIARVAKSLGLSRQALYRRMDKF
CCCEEEECCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GLDKS
CCCCC
>Mature Secondary Structure
MDTILIVDDNHAICQALGLMLELNGYRVLSCHTPEEALGVLTTQEVDLVIQDMNFTRDTT
CCEEEEEECCHHHHHHHHHHEEECCEEEEEECCCHHHHHHHEECCCEEEEECCCCCCCCC
SGEEGRQLFYALREQQADLPIILMTAWTQLETAVELVKAGAADYMGKPWDDAKVLNSITN
CCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHH
LIALYKLSRANHRLERVNHQRQVAIADANLCGIVFGSGAMQRCIDLALQLARSDVSVLIT
HHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEE
GPNGAGKDKLADILHANSPLKNKPFIKVNVGALPMDLLEAELFGAEAGAFTGATKARIGR
CCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHCCC
FEAADGGTLFLDEIGNLPLSGQVKLLRVLQTGEFERLGSHKTQKVKVRVISATNADLAQD
EECCCCCEEEHHHHCCCCCCCCHHHHHHHHCCCHHHHCCCCCEEEEEEEEECCCCHHHHH
IAEGRFREDLFYRLNVIELALPPLNQRTDDILPLVQHFIGSDFSLSKPALQALLHHRWPG
HHHCHHHHHHHHHHEEHEEECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCC
NVRELENACKRAVLLAQGHVLTETDFGLAPVARAIKSSSSVSAVSEQRQFDPQPEMGEQY
CHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHH
SKPVYASASIPANTVFSNESVDVSREEIEAALSLHKGVIARVAKSLGLSRQALYRRMDKF
CCCEEEECCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GLDKS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]