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The map label for this gene is yisQ [H]

Identifier: 120597587

GI number: 120597587

Start: 840342

End: 841802

Strand: Direct

Name: yisQ [H]

Synonym: Sputw3181_0756

Alternate gene names: 120597587

Gene position: 840342-841802 (Clockwise)

Preceding gene: 120597585

Following gene: 120597590

Centisome position: 17.85

GC content: 48.32

Gene sequence:

>1461_bases
ATGTGGTCGTTCTCGGTTATTTTGGGGATTGGCGACATAAGCGGTAAAACTGAACAAAAACTCTCTTACGATTTCATTCT
CCATTTAGTAGGCATTTCTGTGGCAAAAGCACCCAAAACATTGCAGCAGCGCATGAGTATCGTGGCGCTGACTTGGCCTA
TTTTTATCGAGACCTTGCTGCAATCCTTGCTTGGAATAAGTGACATTTTTATGCTCAGCAACTATTCCGATAATGCGGTT
GCTGCGGTTGGGCTCACCACTCAGTTGATGTTTTTTATGATGGTGATGTCCATGATGGTGAGCACGGGCGCGAGCATTTT
GATTAGTCAACACAATGGTGCGGGACAACCGCAGCAGGCGATTGATATTGGTGTTGCAAGCATTGCTTTGAGTCTCGGCT
TAGCCGTGGTGATGGGCGCCTCAATGTTTTTAGGTGCTAAGAGCATTATCGGTTTATTCGCCCTTGAGCATGAGGTTGCA
GGCTTTGGATACGATTATTTAGTCATTTGCGGCAGCTTGAGCATAGGGCTAGTGATGAACATTGCCTTCGCCGCTATTTT
GCGTAGTTATGGCTTTACCCGCTCGGCCATGTTAGTCACCTCGAGCACGGGCTTGATGAATGTGTTAGGCAATTATATTG
CCCTGTATTCTCCCTTTGGTTTGCCTGTATACGGGGTAACAGGGGTGGCGATTTCTACTGTGACCAGCCAGATTATCGGT
GCCTTTATTATGCTGATGGTGATCCGGCATAAGCAAATCCCGCTGCCGCTGCAACGACTTAAGCTCTTACCGCGCAGCAC
TTATTGGCGCGTGATGCGCATTGGCCTGCTTAATGCGGGTGAGATGCTGTCTTACAATATGGCGCAAATGACGATTATCT
ACTTTATCAGTCAGATGGGTACTTTATCGCTCACGGCCTATACCTATGGCTTGAACATTAGCCGTTTTATCTATTGTTTT
GCAGTCGCACTCGGGCAGGCGACGCAAATCCAGACTGGATATTATGTGGGTAAACAATGGTTCGATGAAATCACCACTCG
GGTGCAGCGTTACTGTTTGGTGGGTTTTATTGCTTCATTGACCATAGTATTGCTCTTCTACTGGCAGCGATTCGTTATTG
TCGGCTGGTTGAGTGAAAACGAAGAAGTTATCCAACTAACAGCGTTATTGCTCGCAGGTTCCATCGCCCTTGAAACCGGA
CGAGTGTTTAATCTGGTGATTATCTCGGCCTTAAAGGGCGCCGGTGATGTGGCATTCCCCGTGCGGATTGGTCTCTTTAG
TATGTGGGGCATTGGCGTGTTATTGGCTTGGTTCTTTGGCTTGCATTTAGGTTATGGCGTGTTGGCTGCTTGGCTTGCCG
TTGCGGCAGATGAATGGGTGCGTGGATTGATTATGGTGCAGCGTTGGCGCTCGGGTCGCTGGCAGCGTTTTACGCGTATT
CCGCCAGTAACCCCAGCTTAA

Upstream 100 bases:

>100_bases
AAATCCGGCTGTCAGTCTGGTTTTAACTGAATAACGCTTGTTTTGTGAAATTAATTTTCAAAAAAGTAACATTAAAGTGT
TATTTATGGATTAGTGACGC

Downstream 100 bases:

>100_bases
ACTGTTCTGATATCAAAAAGTCAACGCTTATTGTTTGCCCCATTTACCCGATTTCAGCAGTTCATTTTTAAATTGTAGAT
ACCTTGGGTGCCCTTCATAG

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MWSFSVILGIGDISGKTEQKLSYDFILHLVGISVAKAPKTLQQRMSIVALTWPIFIETLLQSLLGISDIFMLSNYSDNAV
AAVGLTTQLMFFMMVMSMMVSTGASILISQHNGAGQPQQAIDIGVASIALSLGLAVVMGASMFLGAKSIIGLFALEHEVA
GFGYDYLVICGSLSIGLVMNIAFAAILRSYGFTRSAMLVTSSTGLMNVLGNYIALYSPFGLPVYGVTGVAISTVTSQIIG
AFIMLMVIRHKQIPLPLQRLKLLPRSTYWRVMRIGLLNAGEMLSYNMAQMTIIYFISQMGTLSLTAYTYGLNISRFIYCF
AVALGQATQIQTGYYVGKQWFDEITTRVQRYCLVGFIASLTIVLLFYWQRFVIVGWLSENEEVIQLTALLLAGSIALETG
RVFNLVIISALKGAGDVAFPVRIGLFSMWGIGVLLAWFFGLHLGYGVLAAWLAVAADEWVRGLIMVQRWRSGRWQRFTRI
PPVTPA

Sequences:

>Translated_486_residues
MWSFSVILGIGDISGKTEQKLSYDFILHLVGISVAKAPKTLQQRMSIVALTWPIFIETLLQSLLGISDIFMLSNYSDNAV
AAVGLTTQLMFFMMVMSMMVSTGASILISQHNGAGQPQQAIDIGVASIALSLGLAVVMGASMFLGAKSIIGLFALEHEVA
GFGYDYLVICGSLSIGLVMNIAFAAILRSYGFTRSAMLVTSSTGLMNVLGNYIALYSPFGLPVYGVTGVAISTVTSQIIG
AFIMLMVIRHKQIPLPLQRLKLLPRSTYWRVMRIGLLNAGEMLSYNMAQMTIIYFISQMGTLSLTAYTYGLNISRFIYCF
AVALGQATQIQTGYYVGKQWFDEITTRVQRYCLVGFIASLTIVLLFYWQRFVIVGWLSENEEVIQLTALLLAGSIALETG
RVFNLVIISALKGAGDVAFPVRIGLFSMWGIGVLLAWFFGLHLGYGVLAAWLAVAADEWVRGLIMVQRWRSGRWQRFTRI
PPVTPA
>Mature_486_residues
MWSFSVILGIGDISGKTEQKLSYDFILHLVGISVAKAPKTLQQRMSIVALTWPIFIETLLQSLLGISDIFMLSNYSDNAV
AAVGLTTQLMFFMMVMSMMVSTGASILISQHNGAGQPQQAIDIGVASIALSLGLAVVMGASMFLGAKSIIGLFALEHEVA
GFGYDYLVICGSLSIGLVMNIAFAAILRSYGFTRSAMLVTSSTGLMNVLGNYIALYSPFGLPVYGVTGVAISTVTSQIIG
AFIMLMVIRHKQIPLPLQRLKLLPRSTYWRVMRIGLLNAGEMLSYNMAQMTIIYFISQMGTLSLTAYTYGLNISRFIYCF
AVALGQATQIQTGYYVGKQWFDEITTRVQRYCLVGFIASLTIVLLFYWQRFVIVGWLSENEEVIQLTALLLAGSIALETG
RVFNLVIISALKGAGDVAFPVRIGLFSMWGIGVLLAWFFGLHLGYGVLAAWLAVAADEWVRGLIMVQRWRSGRWQRFTRI
PPVTPA

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=454, Percent_Identity=23.568281938326, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 53313; Mature: 53313

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWSFSVILGIGDISGKTEQKLSYDFILHLVGISVAKAPKTLQQRMSIVALTWPIFIETLL
CCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
QSLLGISDIFMLSNYSDNAVAAVGLTTQLMFFMMVMSMMVSTGASILISQHNGAGQPQQA
HHHHCHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHH
IDIGVASIALSLGLAVVMGASMFLGAKSIIGLFALEHEVAGFGYDYLVICGSLSIGLVMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHH
IAFAAILRSYGFTRSAMLVTSSTGLMNVLGNYIALYSPFGLPVYGVTGVAISTVTSQIIG
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
AFIMLMVIRHKQIPLPLQRLKLLPRSTYWRVMRIGLLNAGEMLSYNMAQMTIIYFISQMG
HHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
TLSLTAYTYGLNISRFIYCFAVALGQATQIQTGYYVGKQWFDEITTRVQRYCLVGFIASL
CEEEEEEEECCCHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIVLLFYWQRFVIVGWLSENEEVIQLTALLLAGSIALETGRVFNLVIISALKGAGDVAFP
HHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEHH
VRIGLFSMWGIGVLLAWFFGLHLGYGVLAAWLAVAADEWVRGLIMVQRWRSGRWQRFTRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
PPVTPA
CCCCCC
>Mature Secondary Structure
MWSFSVILGIGDISGKTEQKLSYDFILHLVGISVAKAPKTLQQRMSIVALTWPIFIETLL
CCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
QSLLGISDIFMLSNYSDNAVAAVGLTTQLMFFMMVMSMMVSTGASILISQHNGAGQPQQA
HHHHCHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHH
IDIGVASIALSLGLAVVMGASMFLGAKSIIGLFALEHEVAGFGYDYLVICGSLSIGLVMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHH
IAFAAILRSYGFTRSAMLVTSSTGLMNVLGNYIALYSPFGLPVYGVTGVAISTVTSQIIG
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
AFIMLMVIRHKQIPLPLQRLKLLPRSTYWRVMRIGLLNAGEMLSYNMAQMTIIYFISQMG
HHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
TLSLTAYTYGLNISRFIYCFAVALGQATQIQTGYYVGKQWFDEITTRVQRYCLVGFIASL
CEEEEEEEECCCHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIVLLFYWQRFVIVGWLSENEEVIQLTALLLAGSIALETGRVFNLVIISALKGAGDVAFP
HHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEHH
VRIGLFSMWGIGVLLAWFFGLHLGYGVLAAWLAVAADEWVRGLIMVQRWRSGRWQRFTRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
PPVTPA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]