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The map label for this gene is ctpC [H]

Identifier: 120597581

GI number: 120597581

Start: 832651

End: 834756

Strand: Direct

Name: ctpC [H]

Synonym: Sputw3181_0750

Alternate gene names: 120597581

Gene position: 832651-834756 (Clockwise)

Preceding gene: 120597580

Following gene: 120597584

Centisome position: 17.68

GC content: 46.11

Gene sequence:

>2106_bases
ATGATGAACAATAATGCCGCAGTATTTAAAGCATTAGCTTTAGTCCACCATTGCACTAATCGGGTTCGATGGCGTTATTC
TTTAGCAACGAATAGCCAAGAGCTCAAAGGTTTAGCATTGGCCATTGAGAATCTCGATGAGGTGTATTCTGCGAGGTTTA
ATCCCAAAGCTCGTTCCTTAATTGTTAGCTATAACGCGTCTAAAATATCGATTGAGAAATTAGCCAGCCGAGTGCTACAG
GTTAAGCCTGTCATTTTGGTTGCGGGTGATGGCCAAAATAAAGAGAGCCACCCCGCCCCCCAAAGACTGTTGCTGAATCT
TGCGACATTAATCAGTGTGAATTTTTTACCTATATCGATGCGCTTGCCCGTCTCTCTATTGTCGGCATTGTCTGTGCTAA
GGCATGGTGCTGAGGATGTTGTGAGTAAAGGGTTAACTTCTCATGCGCTAGAAGCCTTGGCCGTGACTATCTCCCTTGGC
AGTGGTGATTATATTGCTGCTAATACCACAGCCTTTATGTTGGAGTTAGGCGAATACCTCGAAGACTCTATCGCTCGTCG
ATCTGACGATATGCTGAAAACCTTGTTGCAGCCCTCGGATAAATTTGTATGGGTTGAACGCAGTGGTGTAGAAATCCAAG
TGGCAACCAATGAAGTGGTTGTCGGCGATACCGTGATCGTGGGTGCAGGTGCTGTGCTGCCTGTAGACGGTACTGTGCTT
GGGGGAGAGGCTTATGTTAATGAAGCCTCAATGACAGGCGAAAGTATGGCAACCCGGAAAAAACGGGGTGATACCGTATT
GTCGGGTACGGTTGTGGAAGATGGCAGATTGAGGATCTACGCAGAGCATGTCGGTGTGGGAACCGCGGCGGCGCGTATTG
CGGATTATGTCGAACAATCGCTCACAGCCAAAAGTGACGTCCAACTTCAGGCTTCATCATTAGCCGATAAATTGGTGCCC
CGAGTACTCACATTAGCAGGTGCTACTTATTTAGTTTCTGGTAACTGGCAGCGCAGTGCCGCTGTTTTACAAGCCGATTA
TTCCTGCGCATTAAAGCTCGCTACACCAGTGGCATTTAAATCGGCCATGTATCGTGCAGGTAAAAACGGGATTTTAATCA
AAGGGGCTACAGCGTTAGAACGACTCGCTCAGGCAGACACTTTTATTTTTGATAAAACGGGTACGCTTACTAAAGGTAAT
CTTGATGTGACCGACTCTGTGGCGTTTGATAGTACCTATTCTGCGAATGATTTGATCTGGCTGGCAGCCTCAGTAGAGGA
GCACTATTTTCACCCGTTGGCCATGGCGGTAGTGGAGGCTTCACAAAGCATTGATGGTCGACATTTTGATCACTCTGAAG
TGGAGTTTATCGTTTCCCACGGTGTGGCGAGTGAAATTGATGGGAAACGTATTGTTGTCGGTTCTCGGCATTTTATTGAA
GAAGATGAGTGTATTGATGTAACACCTTATCTTACTGAAATTGAAAGATTATACAGTGAAGGTAAAACCTTACTTTATAT
TGGATTTGGTGGTGTATTAATCGGTGTTTTAGCACTTAGGGATGCCATTCGTGATGAAAGCGCAGTAACCATACATCGCT
TAAAGCAATTAGGGGTAAAACGAATACTGTTACTTACTGGCGATCAGCAGGATCGTGCCTTGGAGCTTGCCAAAGATCTT
GGTATCGATGAAGTGTATGCAGAGCTATTGCCAGAAGATAAAGCCGAGATCATTGAGCGACTGAGTCAATCGGGGTGCAA
TATTGCCTTTGTGGGGGATGGTATTAATGATGCGCCTGCGTTAGCGGGGGCTCATGTTGGTATTGCCATGCAAAAAGGGG
CTGATATTGCGCGTTTATCCGCAGATATTGCGCTCTTGCAGGATGACATTACCCGAGTGGCCGATGCGAAGGAATTAGCG
AATTTATCTATGGCACTTATCCATGATAACTACCAGTTAACACTGAGGGCTAACACAGGAATACTAGGCGCTGCTGCCGT
TGGTTTACTCAGTCCTGTAGCGGCATCTATATTACACAATGGCACGACTATTGGTATTTTGCTCAATGCCTTACGGGGAA
ATCGCCGCATAACTAATACGGCCTAA

Upstream 100 bases:

>100_bases
CGTTCAGCCGTAAAACTGTATACCGATATTGCTGGCGGGATGGAAGAACTTAAAGAACAGGTTGCAGATATCCAAGCTGA
AATGGCAGTCCAGACTGGTG

Downstream 100 bases:

>100_bases
TATCATCGTTAGAAAGCAAGTTGATCGCGTTTTAGCCGTAAAAGCAAATACCCCTACAGGTGTTAGCTTTTACGGCTTTA
TATTATACAGCGGGACAGAG

Product: heavy metal translocating P-type ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 701; Mature: 701

Protein sequence:

>701_residues
MMNNNAAVFKALALVHHCTNRVRWRYSLATNSQELKGLALAIENLDEVYSARFNPKARSLIVSYNASKISIEKLASRVLQ
VKPVILVAGDGQNKESHPAPQRLLLNLATLISVNFLPISMRLPVSLLSALSVLRHGAEDVVSKGLTSHALEALAVTISLG
SGDYIAANTTAFMLELGEYLEDSIARRSDDMLKTLLQPSDKFVWVERSGVEIQVATNEVVVGDTVIVGAGAVLPVDGTVL
GGEAYVNEASMTGESMATRKKRGDTVLSGTVVEDGRLRIYAEHVGVGTAAARIADYVEQSLTAKSDVQLQASSLADKLVP
RVLTLAGATYLVSGNWQRSAAVLQADYSCALKLATPVAFKSAMYRAGKNGILIKGATALERLAQADTFIFDKTGTLTKGN
LDVTDSVAFDSTYSANDLIWLAASVEEHYFHPLAMAVVEASQSIDGRHFDHSEVEFIVSHGVASEIDGKRIVVGSRHFIE
EDECIDVTPYLTEIERLYSEGKTLLYIGFGGVLIGVLALRDAIRDESAVTIHRLKQLGVKRILLLTGDQQDRALELAKDL
GIDEVYAELLPEDKAEIIERLSQSGCNIAFVGDGINDAPALAGAHVGIAMQKGADIARLSADIALLQDDITRVADAKELA
NLSMALIHDNYQLTLRANTGILGAAAVGLLSPVAASILHNGTTIGILLNALRGNRRITNTA

Sequences:

>Translated_701_residues
MMNNNAAVFKALALVHHCTNRVRWRYSLATNSQELKGLALAIENLDEVYSARFNPKARSLIVSYNASKISIEKLASRVLQ
VKPVILVAGDGQNKESHPAPQRLLLNLATLISVNFLPISMRLPVSLLSALSVLRHGAEDVVSKGLTSHALEALAVTISLG
SGDYIAANTTAFMLELGEYLEDSIARRSDDMLKTLLQPSDKFVWVERSGVEIQVATNEVVVGDTVIVGAGAVLPVDGTVL
GGEAYVNEASMTGESMATRKKRGDTVLSGTVVEDGRLRIYAEHVGVGTAAARIADYVEQSLTAKSDVQLQASSLADKLVP
RVLTLAGATYLVSGNWQRSAAVLQADYSCALKLATPVAFKSAMYRAGKNGILIKGATALERLAQADTFIFDKTGTLTKGN
LDVTDSVAFDSTYSANDLIWLAASVEEHYFHPLAMAVVEASQSIDGRHFDHSEVEFIVSHGVASEIDGKRIVVGSRHFIE
EDECIDVTPYLTEIERLYSEGKTLLYIGFGGVLIGVLALRDAIRDESAVTIHRLKQLGVKRILLLTGDQQDRALELAKDL
GIDEVYAELLPEDKAEIIERLSQSGCNIAFVGDGINDAPALAGAHVGIAMQKGADIARLSADIALLQDDITRVADAKELA
NLSMALIHDNYQLTLRANTGILGAAAVGLLSPVAASILHNGTTIGILLNALRGNRRITNTA
>Mature_701_residues
MMNNNAAVFKALALVHHCTNRVRWRYSLATNSQELKGLALAIENLDEVYSARFNPKARSLIVSYNASKISIEKLASRVLQ
VKPVILVAGDGQNKESHPAPQRLLLNLATLISVNFLPISMRLPVSLLSALSVLRHGAEDVVSKGLTSHALEALAVTISLG
SGDYIAANTTAFMLELGEYLEDSIARRSDDMLKTLLQPSDKFVWVERSGVEIQVATNEVVVGDTVIVGAGAVLPVDGTVL
GGEAYVNEASMTGESMATRKKRGDTVLSGTVVEDGRLRIYAEHVGVGTAAARIADYVEQSLTAKSDVQLQASSLADKLVP
RVLTLAGATYLVSGNWQRSAAVLQADYSCALKLATPVAFKSAMYRAGKNGILIKGATALERLAQADTFIFDKTGTLTKGN
LDVTDSVAFDSTYSANDLIWLAASVEEHYFHPLAMAVVEASQSIDGRHFDHSEVEFIVSHGVASEIDGKRIVVGSRHFIE
EDECIDVTPYLTEIERLYSEGKTLLYIGFGGVLIGVLALRDAIRDESAVTIHRLKQLGVKRILLLTGDQQDRALELAKDL
GIDEVYAELLPEDKAEIIERLSQSGCNIAFVGDGINDAPALAGAHVGIAMQKGADIARLSADIALLQDDITRVADAKELA
NLSMALIHDNYQLTLRANTGILGAAAVGLLSPVAASILHNGTTIGILLNALRGNRRITNTA

Specific function: Involved In Copper Efflux. [C]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI115529486, Length=572, Percent_Identity=28.4965034965035, Blast_Score=212, Evalue=9e-55,
Organism=Homo sapiens, GI55743071, Length=555, Percent_Identity=30.2702702702703, Blast_Score=211, Evalue=2e-54,
Organism=Homo sapiens, GI55743073, Length=525, Percent_Identity=30.6666666666667, Blast_Score=204, Evalue=2e-52,
Organism=Escherichia coli, GI1786691, Length=555, Percent_Identity=33.8738738738739, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI1789879, Length=643, Percent_Identity=30.1710730948678, Blast_Score=206, Evalue=5e-54,
Organism=Escherichia coli, GI1786914, Length=447, Percent_Identity=29.5302013422819, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI2367363, Length=578, Percent_Identity=23.8754325259516, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17556548, Length=596, Percent_Identity=29.6979865771812, Blast_Score=185, Evalue=7e-47,
Organism=Saccharomyces cerevisiae, GI6320475, Length=511, Percent_Identity=29.3542074363992, Blast_Score=185, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6319772, Length=490, Percent_Identity=25.9183673469388, Blast_Score=152, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6325221, Length=522, Percent_Identity=28.1609195402299, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6321430, Length=504, Percent_Identity=27.1825396825397, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321271, Length=187, Percent_Identity=29.4117647058824, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221329854, Length=219, Percent_Identity=33.3333333333333, Blast_Score=121, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281366617, Length=155, Percent_Identity=31.6129032258064, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24668708, Length=155, Percent_Identity=31.6129032258064, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24668704, Length=155, Percent_Identity=31.6129032258064, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161085803, Length=155, Percent_Identity=31.6129032258064, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24668696, Length=155, Percent_Identity=31.6129032258064, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 75128; Mature: 75128

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS01121 CASPASE_HIS ; PS00154 ATPASE_E1_E2 ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNNNAAVFKALALVHHCTNRVRWRYSLATNSQELKGLALAIENLDEVYSARFNPKARSL
CCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEE
IVSYNASKISIEKLASRVLQVKPVILVAGDGQNKESHPAPQRLLLNLATLISVNFLPISM
EEEECCCEEEHHHHHHHHHEECCEEEEECCCCCCCCCCCHHHHHHHHHHHHEEEEEEEEE
RLPVSLLSALSVLRHGAEDVVSKGLTSHALEALAVTISLGSGDYIAANTTAFMLELGEYL
CCHHHHHHHHHHHHCCHHHHHHCCHHHHHHEEEEEEEEECCCCEEEECHHHHHHHHHHHH
EDSIARRSDDMLKTLLQPSDKFVWVERSGVEIQVATNEVVVGDTVIVGAGAVLPVDGTVL
HHHHHHCCHHHHHHHHCCCCCEEEEECCCEEEEEECCEEEECCEEEEECCEEEECCCEEE
GGEAYVNEASMTGESMATRKKRGDTVLSGTVVEDGRLRIYAEHVGVGTAAARIADYVEQS
CCHHHCCHHHCCCHHHHHHHHCCCEEEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHH
LTAKSDVQLQASSLADKLVPRVLTLAGATYLVSGNWQRSAAVLQADYSCALKLATPVAFK
CCCCCCCEEEHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHEEECCCCEEEEECCHHHHH
SAMYRAGKNGILIKGATALERLAQADTFIFDKTGTLTKGNLDVTDSVAFDSTYSANDLIW
HHHHHCCCCCEEEECHHHHHHHHHCCCEEEECCCCEECCCCCCCCCEEECCCCCCCCEEE
LAASVEEHYFHPLAMAVVEASQSIDGRHFDHSEVEFIVSHGVASEIDGKRIVVGSRHFIE
EEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEECCCCCCC
EDECIDVTPYLTEIERLYSEGKTLLYIGFGGVLIGVLALRDAIRDESAVTIHRLKQLGVK
CCCCEECCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCE
RILLLTGDQQDRALELAKDLGIDEVYAELLPEDKAEIIERLSQSGCNIAFVGDGINDAPA
EEEEEECCCHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCCCH
LAGAHVGIAMQKGADIARLSADIALLQDDITRVADAKELANLSMALIHDNYQLTLRANTG
HCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEEEEEEECCC
ILGAAAVGLLSPVAASILHNGTTIGILLNALRGNRRITNTA
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEECCCC
>Mature Secondary Structure
MMNNNAAVFKALALVHHCTNRVRWRYSLATNSQELKGLALAIENLDEVYSARFNPKARSL
CCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEE
IVSYNASKISIEKLASRVLQVKPVILVAGDGQNKESHPAPQRLLLNLATLISVNFLPISM
EEEECCCEEEHHHHHHHHHEECCEEEEECCCCCCCCCCCHHHHHHHHHHHHEEEEEEEEE
RLPVSLLSALSVLRHGAEDVVSKGLTSHALEALAVTISLGSGDYIAANTTAFMLELGEYL
CCHHHHHHHHHHHHCCHHHHHHCCHHHHHHEEEEEEEEECCCCEEEECHHHHHHHHHHHH
EDSIARRSDDMLKTLLQPSDKFVWVERSGVEIQVATNEVVVGDTVIVGAGAVLPVDGTVL
HHHHHHCCHHHHHHHHCCCCCEEEEECCCEEEEEECCEEEECCEEEEECCEEEECCCEEE
GGEAYVNEASMTGESMATRKKRGDTVLSGTVVEDGRLRIYAEHVGVGTAAARIADYVEQS
CCHHHCCHHHCCCHHHHHHHHCCCEEEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHH
LTAKSDVQLQASSLADKLVPRVLTLAGATYLVSGNWQRSAAVLQADYSCALKLATPVAFK
CCCCCCCEEEHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHEEECCCCEEEEECCHHHHH
SAMYRAGKNGILIKGATALERLAQADTFIFDKTGTLTKGNLDVTDSVAFDSTYSANDLIW
HHHHHCCCCCEEEECHHHHHHHHHCCCEEEECCCCEECCCCCCCCCEEECCCCCCCCEEE
LAASVEEHYFHPLAMAVVEASQSIDGRHFDHSEVEFIVSHGVASEIDGKRIVVGSRHFIE
EEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEECCCCCCC
EDECIDVTPYLTEIERLYSEGKTLLYIGFGGVLIGVLALRDAIRDESAVTIHRLKQLGVK
CCCCEECCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCE
RILLLTGDQQDRALELAKDLGIDEVYAELLPEDKAEIIERLSQSGCNIAFVGDGINDAPA
EEEEEECCCHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCCCH
LAGAHVGIAMQKGADIARLSADIALLQDDITRVADAKELANLSMALIHDNYQLTLRANTG
HCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEEEEEEECCC
ILGAAAVGLLSPVAASILHNGTTIGILLNALRGNRRITNTA
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]