Click here to switch to the map view.

The map label for this gene is plsC [H]

Identifier: 120597464

GI number: 120597464

Start: 689829

End: 690614

Strand: Direct

Name: plsC [H]

Synonym: Sputw3181_0633

Alternate gene names: 120597464

Gene position: 689829-690614 (Clockwise)

Preceding gene: 120597463

Following gene: 120597465

Centisome position: 14.65

GC content: 42.62

Gene sequence:

>786_bases
ATGCTGGCTATACTGTCGCCAATTTTATCGTTGGAGTATGCTGTGCTGTTAATCGTCAGATCTATGCTGTTGGCGGTGTC
TTTGTTGCTTGCCTTTATTTTTGGTGGATTGGTGTGTTTACTCAGACCTCGACACCGTGACAATGTACATATGTTCGCCA
AGATCTTCTCTTCTGTTGCACCGATCCTAGGGATAAAAGTGATCGTTCGTCGGCATAAAGAGGTGCAGGATGGCCCCTAT
ATTTTCTTAGCAAATCATCAGAATAACTTCGATCTTTTTACTCACACTAAGGCCGTTCCTAAGGGCACGGTTAGCTTAGG
TAAGAAAAGTTTGGTTTGGATGCCACTATTTGGCCAAATTTATTGGTTGTCGGGCAATATTCTCATCGATCGGAAAAATC
GACACAGTGCCTTTGATACGATGGCGAAGACAGTTGAGAAAATTAAGCAAAAAAGTTTATCTGTATGGATTTTTCCTGAA
GGCACCCGTTCTCGAGGACGTGGTTTATTACCCTTCAAGGCGGGGGCTTTTCATACAGCGATTGCAGCAGGTGTCCCAAT
TGTGCCCGTGTTAGCTTCCTGTCAGAGCCATATTAATTTAAATCGTTGGGATAATGGGGTTGTTATTATCGAAATGATGG
CGCCAATACCCACTGCGGATATAGACAAAGCGGATGTTAAAGCTTTTTCTGCACAAATTTATGACAGTATGTCGGCAAAA
TTTAATGAGATAAACCGAGAAGCGGCAACATTAATGGGTAAAACTCCTATGGATGATGGCGTATAA

Upstream 100 bases:

>100_bases
TTAAAGCCCATCAACACACTGTATTTACAATGAGTTGATGGGCTTTTTTTTGTTAGCGAATCGGCTTACAGATGTAAACA
ATATATTGAGTCCATAGGCC

Downstream 100 bases:

>100_bases
TAGCCTCAATTTGAGCCAGATTTATCTTAACGGAGACACGTTTATGTCTATTGAAAGTCAGTTAAAAGCACAACTTGCCG
AGAATCGCGACATAGTGCAA

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MLAILSPILSLEYAVLLIVRSMLLAVSLLLAFIFGGLVCLLRPRHRDNVHMFAKIFSSVAPILGIKVIVRRHKEVQDGPY
IFLANHQNNFDLFTHTKAVPKGTVSLGKKSLVWMPLFGQIYWLSGNILIDRKNRHSAFDTMAKTVEKIKQKSLSVWIFPE
GTRSRGRGLLPFKAGAFHTAIAAGVPIVPVLASCQSHINLNRWDNGVVIIEMMAPIPTADIDKADVKAFSAQIYDSMSAK
FNEINREAATLMGKTPMDDGV

Sequences:

>Translated_261_residues
MLAILSPILSLEYAVLLIVRSMLLAVSLLLAFIFGGLVCLLRPRHRDNVHMFAKIFSSVAPILGIKVIVRRHKEVQDGPY
IFLANHQNNFDLFTHTKAVPKGTVSLGKKSLVWMPLFGQIYWLSGNILIDRKNRHSAFDTMAKTVEKIKQKSLSVWIFPE
GTRSRGRGLLPFKAGAFHTAIAAGVPIVPVLASCQSHINLNRWDNGVVIIEMMAPIPTADIDKADVKAFSAQIYDSMSAK
FNEINREAATLMGKTPMDDGV
>Mature_261_residues
MLAILSPILSLEYAVLLIVRSMLLAVSLLLAFIFGGLVCLLRPRHRDNVHMFAKIFSSVAPILGIKVIVRRHKEVQDGPY
IFLANHQNNFDLFTHTKAVPKGTVSLGKKSLVWMPLFGQIYWLSGNILIDRKNRHSAFDTMAKTVEKIKQKSLSVWIFPE
GTRSRGRGLLPFKAGAFHTAIAAGVPIVPVLASCQSHINLNRWDNGVVIIEMMAPIPTADIDKADVKAFSAQIYDSMSAK
FNEINREAATLMGKTPMDDGV

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=215, Percent_Identity=33.0232558139535, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI15100175, Length=215, Percent_Identity=33.0232558139535, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI6041665, Length=246, Percent_Identity=32.520325203252, Blast_Score=128, Evalue=4e-30,
Organism=Escherichia coli, GI1789395, Length=237, Percent_Identity=47.6793248945148, Blast_Score=237, Evalue=6e-64,
Organism=Caenorhabditis elegans, GI17564032, Length=201, Percent_Identity=33.8308457711443, Blast_Score=121, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17568319, Length=238, Percent_Identity=31.5126050420168, Blast_Score=115, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6320151, Length=243, Percent_Identity=33.3333333333333, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI281364648, Length=269, Percent_Identity=27.1375464684015, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24582856, Length=269, Percent_Identity=27.1375464684015, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24582854, Length=269, Percent_Identity=27.1375464684015, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24641614, Length=216, Percent_Identity=30.5555555555556, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24641612, Length=216, Percent_Identity=30.5555555555556, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 28923; Mature: 28923

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAILSPILSLEYAVLLIVRSMLLAVSLLLAFIFGGLVCLLRPRHRDNVHMFAKIFSSVA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
PILGIKVIVRRHKEVQDGPYIFLANHQNNFDLFTHTKAVPKGTVSLGKKSLVWMPLFGQI
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCCCCCHHHCCCCCEEEEECCCEE
YWLSGNILIDRKNRHSAFDTMAKTVEKIKQKSLSVWIFPEGTRSRGRGLLPFKAGAFHTA
EEEECCEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHH
IAAGVPIVPVLASCQSHINLNRWDNGVVIIEMMAPIPTADIDKADVKAFSAQIYDSMSAK
HHCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
FNEINREAATLMGKTPMDDGV
HHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLAILSPILSLEYAVLLIVRSMLLAVSLLLAFIFGGLVCLLRPRHRDNVHMFAKIFSSVA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
PILGIKVIVRRHKEVQDGPYIFLANHQNNFDLFTHTKAVPKGTVSLGKKSLVWMPLFGQI
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCCCCCHHHCCCCCEEEEECCCEE
YWLSGNILIDRKNRHSAFDTMAKTVEKIKQKSLSVWIFPEGTRSRGRGLLPFKAGAFHTA
EEEECCEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHH
IAAGVPIVPVLASCQSHINLNRWDNGVVIIEMMAPIPTADIDKADVKAFSAQIYDSMSAK
HHCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
FNEINREAATLMGKTPMDDGV
HHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1557036; 9278503 [H]