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The map label for this gene is ubiA

Identifier: 120597400

GI number: 120597400

Start: 625360

End: 626220

Strand: Direct

Name: ubiA

Synonym: Sputw3181_0569

Alternate gene names: 120597400

Gene position: 625360-626220 (Clockwise)

Preceding gene: 120597399

Following gene: 120597401

Centisome position: 13.28

GC content: 45.18

Gene sequence:

>861_bases
ATGAATTTAAAGCAGAAGTGGGACGTGTATTCCCGTCTGACTCGACTCGACCGTCCTATCGGTACGTTATTATTGATGTG
GCCATGCTTGATGGCGCTGATGTTAGCGGCGGGTGGTATGCCCGATCTTAAGGTATTGATCATATTCATTATTGGCGTGG
TGATCATGCGTGCCTGTGGCTGCATTATTAACGACTATGCCGATCGCGATCTTGACTCTTTTGTGGAGCGCACTAAATCT
CGGCCGCTGGCCAGTGGCGAAATCAGTACTAAAGAAGCCTTGATACTGTTTGTCGTCTTAGGTTTATCTGCATTTGGTTT
AGTCTTATTACTCAATGGATTAGTGGTTAAATTATCCGTTGTTGGCATTATCCTCACTATCATTTATCCCTTCACCAAAC
GCATTACTAATATGCCGCAGATGTTTTTAGGCGTGGTGTGGAGTTGGTCTATCCCTATGGCGTATGCCGCGCAGACGGGT
GAAGTACCGATGGAGGCTTGGTGGTTATTTGCGGCGAATTGGTTTTGGACAGTTGCCTACGACACTATGTATGCCATGGT
TGATAGGGACGATGATCTTAAGGTGGGTATAAAATCCACTGCCATTTTGTTCGGTAAATATGACCGCCAAATCATAGGCT
TATTTCAGATTGCTGCACTAGTCTGTTTTATTGCTGCGGGTTGGAGTGCTGAGCGCGGTTTACTCTATGGCCTTGGTTTA
CTGACTTTTGTTGGCTTTAGTACTTACCAACAAATGCTGATTTTTGGTCGTGAACGCGCCCCTTGTTTTAAGGCTTTTCT
TAACAATAACTGGGCGGGACTCGCATTATTTGTTGGCTTGGGGGCTGATTATCTAATCTAA

Upstream 100 bases:

>100_bases
GGGTGGGAATTCGCGTTCAGGGTTAGCTTAGGTATATGATGCTAACCCATAGGGATGAAGGCGAAAATGGTAGATTATTA
GGCGTGGGAGTACCTCGTTA

Downstream 100 bases:

>100_bases
ACGTTTGTCGTTCACGATTTTTGTTTACGGCTAAGGCTAAGTTGTTCAGTTTTATCAGGAGCACTATCAAAGGAGGTGAT
GTATGCCGTGCCAGTTAACC

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MNLKQKWDVYSRLTRLDRPIGTLLLMWPCLMALMLAAGGMPDLKVLIIFIIGVVIMRACGCIINDYADRDLDSFVERTKS
RPLASGEISTKEALILFVVLGLSAFGLVLLLNGLVVKLSVVGIILTIIYPFTKRITNMPQMFLGVVWSWSIPMAYAAQTG
EVPMEAWWLFAANWFWTVAYDTMYAMVDRDDDLKVGIKSTAILFGKYDRQIIGLFQIAALVCFIAAGWSAERGLLYGLGL
LTFVGFSTYQQMLIFGRERAPCFKAFLNNNWAGLALFVGLGADYLI

Sequences:

>Translated_286_residues
MNLKQKWDVYSRLTRLDRPIGTLLLMWPCLMALMLAAGGMPDLKVLIIFIIGVVIMRACGCIINDYADRDLDSFVERTKS
RPLASGEISTKEALILFVVLGLSAFGLVLLLNGLVVKLSVVGIILTIIYPFTKRITNMPQMFLGVVWSWSIPMAYAAQTG
EVPMEAWWLFAANWFWTVAYDTMYAMVDRDDDLKVGIKSTAILFGKYDRQIIGLFQIAALVCFIAAGWSAERGLLYGLGL
LTFVGFSTYQQMLIFGRERAPCFKAFLNNNWAGLALFVGLGADYLI
>Mature_286_residues
MNLKQKWDVYSRLTRLDRPIGTLLLMWPCLMALMLAAGGMPDLKVLIIFIIGVVIMRACGCIINDYADRDLDSFVERTKS
RPLASGEISTKEALILFVVLGLSAFGLVLLLNGLVVKLSVVGIILTIIYPFTKRITNMPQMFLGVVWSWSIPMAYAAQTG
EVPMEAWWLFAANWFWTVAYDTMYAMVDRDDDLKVGIKSTAILFGKYDRQIIGLFQIAALVCFIAAGWSAERGLLYGLGL
LTFVGFSTYQQMLIFGRERAPCFKAFLNNNWAGLALFVGLGADYLI

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=277, Percent_Identity=36.4620938628159, Blast_Score=158, Evalue=5e-39,
Organism=Escherichia coli, GI1790473, Length=281, Percent_Identity=52.3131672597865, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1786631, Length=162, Percent_Identity=30.2469135802469, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17553718, Length=280, Percent_Identity=35, Blast_Score=168, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI32565247, Length=286, Percent_Identity=34.2657342657343, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17553720, Length=347, Percent_Identity=28.2420749279539, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI32565245, Length=145, Percent_Identity=42.7586206896552, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32565243, Length=136, Percent_Identity=42.6470588235294, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324370, Length=294, Percent_Identity=31.6326530612245, Blast_Score=142, Evalue=7e-35,
Organism=Drosophila melanogaster, GI21355567, Length=276, Percent_Identity=41.304347826087, Blast_Score=184, Evalue=7e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 31960; Mature: 31960

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHCCCHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHCCCHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA