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The map label for this gene is uxuR [H]

Identifier: 120597390

GI number: 120597390

Start: 611869

End: 612588

Strand: Direct

Name: uxuR [H]

Synonym: Sputw3181_0559

Alternate gene names: 120597390

Gene position: 611869-612588 (Clockwise)

Preceding gene: 120597385

Following gene: 120597396

Centisome position: 13.0

GC content: 42.36

Gene sequence:

>720_bases
GTGCATATATTCAAGCCAATTAAGCAGATAAAAGCATCGAGTGAAGTTGGACAACAACTCAAAAATGCTATTTTAGGCGG
TGATTATAAAGCGGGTGATAAACTGCCTTCCGAGCGTGAATTGATCGAACTATTTCAAGTTAGCCGTACCGTAATAAGGG
AGGCAATTAAAAGCCTCGAAGCGGGAGGTTTGGTAGAGATTCGTCAAGGTGCTACGGGCGGTGCGTTTGTTAAGCACTTA
ACTTTCGAGCGCTTAAGTGATGCTTGCCACGATTTGTTTATGATGGGGAAACTCTCATTACCTGAACTATGCCAAGCGCG
TATGCTGATTGAGCCGCAAGTGGCTAGAATGGCTGCTAAAAATTGCACGCCAGAGCAAGCCTTAATCTTGTTAGAAGCCG
ATCGCCATGAAAATGATACCAGTGCTTACCCTGATACCGTTACATTGCGTTCACAAGTGCATTATTTATTAGCCGAAATG
TCGGGTAATCGGTTTTTAGAGGCCATTGTTAAATCTTTACTGATTTTATTACGTAATCAGACTATGAAATATGAGCCACC
AACAGATGAGATCCATCCTCTAGGGTTACACAGTGTGATTGTTGAGGCGGTTGTCGCTAAAGATGAAGATAAAGCAGAAG
CTGAAATGCTGGCTCATCTCGAGGATTTTAATGTTCGCCTTCGAGAAATTGAGCGTAAATATAAAAATAAGCAAGCCTAG

Upstream 100 bases:

>100_bases
TTTTTTAATCACTAATATAGGATGTACGCGGATACTTTTTCTGCGTGAATGAGTCGGTTTATGGTAAGATGGGCGCATTA
AGCATATTCGGGATAATCAA

Downstream 100 bases:

>100_bases
CTTTACCCTTGTTTCACCACGATTAAAACCACGCTATACGTGAAAAAAAGATGGAATACCTGTCTGAACTGATGGGTATT
TTCATTTGATTTTTAAAGCA

Product: regulatory protein GntR, HTH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MHIFKPIKQIKASSEVGQQLKNAILGGDYKAGDKLPSERELIELFQVSRTVIREAIKSLEAGGLVEIRQGATGGAFVKHL
TFERLSDACHDLFMMGKLSLPELCQARMLIEPQVARMAAKNCTPEQALILLEADRHENDTSAYPDTVTLRSQVHYLLAEM
SGNRFLEAIVKSLLILLRNQTMKYEPPTDEIHPLGLHSVIVEAVVAKDEDKAEAEMLAHLEDFNVRLREIERKYKNKQA

Sequences:

>Translated_239_residues
MHIFKPIKQIKASSEVGQQLKNAILGGDYKAGDKLPSERELIELFQVSRTVIREAIKSLEAGGLVEIRQGATGGAFVKHL
TFERLSDACHDLFMMGKLSLPELCQARMLIEPQVARMAAKNCTPEQALILLEADRHENDTSAYPDTVTLRSQVHYLLAEM
SGNRFLEAIVKSLLILLRNQTMKYEPPTDEIHPLGLHSVIVEAVVAKDEDKAEAEMLAHLEDFNVRLREIERKYKNKQA
>Mature_239_residues
MHIFKPIKQIKASSEVGQQLKNAILGGDYKAGDKLPSERELIELFQVSRTVIREAIKSLEAGGLVEIRQGATGGAFVKHL
TFERLSDACHDLFMMGKLSLPELCQARMLIEPQVARMAAKNCTPEQALILLEADRHENDTSAYPDTVTLRSQVHYLLAEM
SGNRFLEAIVKSLLILLRNQTMKYEPPTDEIHPLGLHSVIVEAVVAKDEDKAEAEMLAHLEDFNVRLREIERKYKNKQA

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=238, Percent_Identity=31.9327731092437, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI87082208, Length=219, Percent_Identity=29.6803652968037, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786303, Length=122, Percent_Identity=40.9836065573771, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789621, Length=227, Percent_Identity=31.2775330396476, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790032, Length=236, Percent_Identity=27.5423728813559, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26888; Mature: 26888

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIFKPIKQIKASSEVGQQLKNAILGGDYKAGDKLPSERELIELFQVSRTVIREAIKSLE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
AGGLVEIRQGATGGAFVKHLTFERLSDACHDLFMMGKLSLPELCQARMLIEPQVARMAAK
CCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHH
NCTPEQALILLEADRHENDTSAYPDTVTLRSQVHYLLAEMSGNRFLEAIVKSLLILLRNQ
CCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
TMKYEPPTDEIHPLGLHSVIVEAVVAKDEDKAEAEMLAHLEDFNVRLREIERKYKNKQA
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHIFKPIKQIKASSEVGQQLKNAILGGDYKAGDKLPSERELIELFQVSRTVIREAIKSLE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
AGGLVEIRQGATGGAFVKHLTFERLSDACHDLFMMGKLSLPELCQARMLIEPQVARMAAK
CCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHH
NCTPEQALILLEADRHENDTSAYPDTVTLRSQVHYLLAEMSGNRFLEAIVKSLLILLRNQ
CCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
TMKYEPPTDEIHPLGLHSVIVEAVVAKDEDKAEAEMLAHLEDFNVRLREIERKYKNKQA
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]