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The map label for this gene is lspA [H]

Identifier: 120597271

GI number: 120597271

Start: 478920

End: 479432

Strand: Direct

Name: lspA [H]

Synonym: Sputw3181_0440

Alternate gene names: 120597271

Gene position: 478920-479432 (Clockwise)

Preceding gene: 120597270

Following gene: 120597272

Centisome position: 10.17

GC content: 49.32

Gene sequence:

>513_bases
ATGTCCATTTTTGGCAAACATCTGTCACCGTACGCTCTGTTGTCCATCTCCGGCCTGCTGGCAGCGTCTGATCAGGCCGT
AAAATGGCTGGTGCAACAATCAATGGCATATGGCGAGTCTATTTCAGTGACCTCATTCTTTAACTGGGTACACGTATGGA
ATACCGGTGCCGCATTCAGTCTTTTTGCGAATGGTGGAGGCTGGCAGCGCTACTTTTTTATCGGAATCGCGGTAGTGGTC
TCGATTTTTCTGATCAAGCTGATCCTTGAAAATCGTCATAAAGGAGAAGCCATCGCTTGCAGTCTTATCCTCGGTGGCGC
CATGGGCAACCTGATTGACCGGGTCTTTCGCGGCTATGTTGTGGATTCCTTTGATTTCTATTGGCGAGACTGGCATTGGC
CGGCCTTCAACCTGGCTGATATTGCAATTGTCCTCGGTGCCTTACTTTTAGTTTCCAGCAGCTTGTTGGGTAAAAAAGCA
AACACCAATGCCGAGCCGGATGGATCTGACTGA

Upstream 100 bases:

>100_bases
GTGGACCGGGTCCAATTATCCGGATCTGATTATCGGCACCATCGCGGGGGTAATTGTACTTAACGGTGCTAGACGCATTC
TGGCGCTCAAGGATTAAGCA

Downstream 100 bases:

>100_bases
CACCTACGCCTATACAACACCATGACCGAACTTCCCGACAACATCCTTCACCTGCCGCAATACCAAGTACTGGGCTGCAA
ATCAACCGACGACGAAATGC

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MSIFGKHLSPYALLSISGLLAASDQAVKWLVQQSMAYGESISVTSFFNWVHVWNTGAAFSLFANGGGWQRYFFIGIAVVV
SIFLIKLILENRHKGEAIACSLILGGAMGNLIDRVFRGYVVDSFDFYWRDWHWPAFNLADIAIVLGALLLVSSSLLGKKA
NTNAEPDGSD

Sequences:

>Translated_170_residues
MSIFGKHLSPYALLSISGLLAASDQAVKWLVQQSMAYGESISVTSFFNWVHVWNTGAAFSLFANGGGWQRYFFIGIAVVV
SIFLIKLILENRHKGEAIACSLILGGAMGNLIDRVFRGYVVDSFDFYWRDWHWPAFNLADIAIVLGALLLVSSSLLGKKA
NTNAEPDGSD
>Mature_169_residues
SIFGKHLSPYALLSISGLLAASDQAVKWLVQQSMAYGESISVTSFFNWVHVWNTGAAFSLFANGGGWQRYFFIGIAVVVS
IFLIKLILENRHKGEAIACSLILGGAMGNLIDRVFRGYVVDSFDFYWRDWHWPAFNLADIAIVLGALLLVSSSLLGKKAN
TNAEPDGSD

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=142, Percent_Identity=43.6619718309859, Blast_Score=117, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 18652; Mature: 18520

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIFGKHLSPYALLSISGLLAASDQAVKWLVQQSMAYGESISVTSFFNWVHVWNTGAAFS
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHEEECCCCEEE
LFANGGGWQRYFFIGIAVVVSIFLIKLILENRHKGEAIACSLILGGAMGNLIDRVFRGYV
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VDSFDFYWRDWHWPAFNLADIAIVLGALLLVSSSLLGKKANTNAEPDGSD
HCCCHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SIFGKHLSPYALLSISGLLAASDQAVKWLVQQSMAYGESISVTSFFNWVHVWNTGAAFS
CCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHEEECCCCEEE
LFANGGGWQRYFFIGIAVVVSIFLIKLILENRHKGEAIACSLILGGAMGNLIDRVFRGYV
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VDSFDFYWRDWHWPAFNLADIAIVLGALLLVSSSLLGKKANTNAEPDGSD
HCCCHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA