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The map label for this gene is czcC [H]

Identifier: 120597181

GI number: 120597181

Start: 376250

End: 377533

Strand: Direct

Name: czcC [H]

Synonym: Sputw3181_0350

Alternate gene names: 120597181

Gene position: 376250-377533 (Clockwise)

Preceding gene: 120597180

Following gene: 120597182

Centisome position: 7.99

GC content: 47.9

Gene sequence:

>1284_bases
ATGAAAGCTATTCTTTGTAAACGCACAGCCAAAAAACCGATAGGCCATCGGTTTTCTGCTGCATTGATAGGAATGAGTAT
TATCCTGTCGGTATCCGCAGCGACAGATGAAAACCCACAAAAAATCAGTTTATCTGATGCGGTTACCATGACTCTCACTC
ATCATCCTGATTTACAAGCTTTTGTATCGCAGCAGCGAGTCTGGGAGGGGCGTATTCAGCAAGCGAGTGTCGGTGAACGC
CCAGAAATTGGGCTGATGATTGAGGATGCGTTAGGCACAGGGGAACACAGTGCATTGAAAAGTATGCAATCTACGCTCAC
CTTCTCATGGTTGCTGCAACAGGATTTAATTGATAGTCGTGTTAACACGGCAAAAACAGAAGCCACTAAACTGGCCATAG
AGAAGCAAATCAAGGCGCTCGATTTGTCTTCACAGGTGGCTAAGCACTTTATCGATATACTGGTTAAACAGGAGCGCCTT
AAGCTCAATGTGATGGCAAAGGCTCAGGCTGAGAACGTTGTTGGTACGATTGCCAAGCGGGTGCAAGTAGGTAAAAGTTC
GGCGGTTGAAATGCAGTTGGCAAAGGCTGAATTTATCCGCCGAGGACTGGCGGTCGAAGATATCGAACACGAGCTGCAAG
CGAGCCAGTATCAACTAGCCTCTTTTTGGGGAAAGCCTCAAGCATCATATTATTTCAACGGTGATCTGCTGGACATGCCA
ACTGTGCCGTCGGTTGACAGTCAGCTTACCCTGCTAAAGCAGAATCCGCGTTTTCAACAGTTTGCCAGTGCTCAGCGTAT
TGCTCAGTCACAAATGGAACTGGCACGAATTGAAGCCAAACCCCAGTGGCAATTTACCGCTGGGGTCCGTCGTTATGAGG
CAAGCGATGACTTTGGTTTAGTGGCAGGCGTCTCTATCCCTTGGGGCACAAGTGACCGTAATGCAGGGACAATCGCAGCC
CTCCACGCTCAGCAGGATGTGTTGGCCAACGAACAAAGCGCATTAATGCAAGCTCAAGATGCTCAACTCTATGTACTGCT
ACAGGAAATGGCACACTCTGCGCATGTGATAGATACAGTGCGCAACAGCATAGTGCCCACCCTCGAAAAAGCCCTGTCAG
AGGCAAGCAATGCTTTTGATAAAGGTCAACTCAGTTACAACCAATACAATGATGTGTATCGGGAATTACTCAGTGCTCAA
TATCAGTTGCTGGATGCCTTTGAAAGCCTGCATTTGCAACACATCGAAATTCAACGCCTGACGGGTACGTCCATTTCTCA
GTGA

Upstream 100 bases:

>100_bases
ATTGTGTTGTTAGTCATAGCACCAGTATTAACCGCCTCCACGGTGGATAGCCTCCACCATATTATCGAAACTTTTTTCAC
CCATTAAGTAAGGATTGGGA

Downstream 100 bases:

>100_bases
GATTACTTATGAAAAATAACCACATCCTTTCGTCACTGAGTTTGGCGATACTGCTCAGTATGGGTATGAACGCCGTCATC
CCAACACCTGTAATGGCTTC

Product: outer membrane efflux protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MKAILCKRTAKKPIGHRFSAALIGMSIILSVSAATDENPQKISLSDAVTMTLTHHPDLQAFVSQQRVWEGRIQQASVGER
PEIGLMIEDALGTGEHSALKSMQSTLTFSWLLQQDLIDSRVNTAKTEATKLAIEKQIKALDLSSQVAKHFIDILVKQERL
KLNVMAKAQAENVVGTIAKRVQVGKSSAVEMQLAKAEFIRRGLAVEDIEHELQASQYQLASFWGKPQASYYFNGDLLDMP
TVPSVDSQLTLLKQNPRFQQFASAQRIAQSQMELARIEAKPQWQFTAGVRRYEASDDFGLVAGVSIPWGTSDRNAGTIAA
LHAQQDVLANEQSALMQAQDAQLYVLLQEMAHSAHVIDTVRNSIVPTLEKALSEASNAFDKGQLSYNQYNDVYRELLSAQ
YQLLDAFESLHLQHIEIQRLTGTSISQ

Sequences:

>Translated_427_residues
MKAILCKRTAKKPIGHRFSAALIGMSIILSVSAATDENPQKISLSDAVTMTLTHHPDLQAFVSQQRVWEGRIQQASVGER
PEIGLMIEDALGTGEHSALKSMQSTLTFSWLLQQDLIDSRVNTAKTEATKLAIEKQIKALDLSSQVAKHFIDILVKQERL
KLNVMAKAQAENVVGTIAKRVQVGKSSAVEMQLAKAEFIRRGLAVEDIEHELQASQYQLASFWGKPQASYYFNGDLLDMP
TVPSVDSQLTLLKQNPRFQQFASAQRIAQSQMELARIEAKPQWQFTAGVRRYEASDDFGLVAGVSIPWGTSDRNAGTIAA
LHAQQDVLANEQSALMQAQDAQLYVLLQEMAHSAHVIDTVRNSIVPTLEKALSEASNAFDKGQLSYNQYNDVYRELLSAQ
YQLLDAFESLHLQHIEIQRLTGTSISQ
>Mature_427_residues
MKAILCKRTAKKPIGHRFSAALIGMSIILSVSAATDENPQKISLSDAVTMTLTHHPDLQAFVSQQRVWEGRIQQASVGER
PEIGLMIEDALGTGEHSALKSMQSTLTFSWLLQQDLIDSRVNTAKTEATKLAIEKQIKALDLSSQVAKHFIDILVKQERL
KLNVMAKAQAENVVGTIAKRVQVGKSSAVEMQLAKAEFIRRGLAVEDIEHELQASQYQLASFWGKPQASYYFNGDLLDMP
TVPSVDSQLTLLKQNPRFQQFASAQRIAQSQMELARIEAKPQWQFTAGVRRYEASDDFGLVAGVSIPWGTSDRNAGTIAA
LHAQQDVLANEQSALMQAQDAQLYVLLQEMAHSAHVIDTVRNSIVPTLEKALSEASNAFDKGQLSYNQYNDVYRELLSAQ
YQLLDAFESLHLQHIEIQRLTGTSISQ

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 47345; Mature: 47345

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAILCKRTAKKPIGHRFSAALIGMSIILSVSAATDENPQKISLSDAVTMTLTHHPDLQA
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCCCCCEEEECCEEEEEEECCCCHHH
FVSQQRVWEGRIQQASVGERPEIGLMIEDALGTGEHSALKSMQSTLTFSWLLQQDLIDSR
HHHHHHHHHHCCHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VNTAKTEATKLAIEKQIKALDLSSQVAKHFIDILVKQERLKLNVMAKAQAENVVGTIAKR
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHH
VQVGKSSAVEMQLAKAEFIRRGLAVEDIEHELQASQYQLASFWGKPQASYYFNGDLLDMP
HHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEECCC
TVPSVDSQLTLLKQNPRFQQFASAQRIAQSQMELARIEAKPQWQFTAGVRRYEASDDFGL
CCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCCCE
VAGVSIPWGTSDRNAGTIAALHAQQDVLANEQSALMQAQDAQLYVLLQEMAHSAHVIDTV
EEECCCCCCCCCCCCCEEEEEECHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RNSIVPTLEKALSEASNAFDKGQLSYNQYNDVYRELLSAQYQLLDAFESLHLQHIEIQRL
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEEE
TGTSISQ
CCCCCCC
>Mature Secondary Structure
MKAILCKRTAKKPIGHRFSAALIGMSIILSVSAATDENPQKISLSDAVTMTLTHHPDLQA
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCCCCCEEEECCEEEEEEECCCCHHH
FVSQQRVWEGRIQQASVGERPEIGLMIEDALGTGEHSALKSMQSTLTFSWLLQQDLIDSR
HHHHHHHHHHCCHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VNTAKTEATKLAIEKQIKALDLSSQVAKHFIDILVKQERLKLNVMAKAQAENVVGTIAKR
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHH
VQVGKSSAVEMQLAKAEFIRRGLAVEDIEHELQASQYQLASFWGKPQASYYFNGDLLDMP
HHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEECCC
TVPSVDSQLTLLKQNPRFQQFASAQRIAQSQMELARIEAKPQWQFTAGVRRYEASDDFGL
CCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCCCE
VAGVSIPWGTSDRNAGTIAALHAQQDVLANEQSALMQAQDAQLYVLLQEMAHSAHVIDTV
EEECCCCCCCCCCCCCEEEEEECHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RNSIVPTLEKALSEASNAFDKGQLSYNQYNDVYRELLSAQYQLLDAFESLHLQHIEIQRL
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEEE
TGTSISQ
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]