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The map label for this gene is fieF [H]

Identifier: 120597051

GI number: 120597051

Start: 242903

End: 243784

Strand: Direct

Name: fieF [H]

Synonym: Sputw3181_0219

Alternate gene names: 120597051

Gene position: 242903-243784 (Clockwise)

Preceding gene: 120597050

Following gene: 120597052

Centisome position: 5.16

GC content: 44.56

Gene sequence:

>882_bases
ATGACTCAAACTTCCCAATACGATTTTTGGGTCAAATTGGCTAGCCGCGCCTCTGTGGCTACCGCTTTGACCCTTATTAT
TATCAAACTCTTAGCTTGGTTATATTCAGGCTCTGCCAGTATGTTGGCTTCCTTGACGGATTCCTTTGCAGATGCACTTG
CTTCTATTGTTAATTTTATTGCTATTCGTTACGCAATCGTTCCTGCCGATCAGGATCACAGATATGGTCATGGAAAAGCA
GAGCCCTTAGCGTCCCTTGCGCAGTCAGCCTTTATTATGGGTTCAGCCTTTTTGTTGCTGTTTTATGGCGGAGAACGCCT
TATTACTCCTGCACCAGTGGAGTATGCCACCCTAGGGGTTGTGGTTTCTGTAGTTGCTATAGCGTTGACATTGGCGCTGG
TCATGTTGCAAAAACGGGCGCTTGCCGCAACTAATAGCACAGTGGTGGAAGCAGATTCATTACACTACAAGTCCGACTTA
TTCCTCAATGCCGCTGTGTTATTAGCATTAGTGTTATCCCAATATGGCTGGTGGTGGGCCGATGGTTTATTTGCCGTCCT
GATTGCATTTTATATTGGTCATCAAGCCTTTGGATTAGGTTATCGTTCAATTCAAGCACTGTTAGATCGAGAATTAGACG
AAGAAACACGTCAGCAAATCAAGCAGATTGCGAAGGAAGATCCTCGGGTGCAAGGGCTACATGATTTACGAACTCGTCAA
GCAGGCAAAACTGTTTTTATTCAATTTCATTTAGAACTCGATGGCAATTTAAGTTTAAATGAAGCCCACAGTATCGCCGA
TACTACAGGCTTGCGAGTCAAGGCTGCATTTGAGGATGCTGAGGTCATTATTCACCAAGATCCGGTGAAACTTGAAGAGT
GA

Upstream 100 bases:

>100_bases
AGTTTAAAGCACGATTTGAAGCACAAGCTGGTAAAGAACCTCGCGGTTAAGTGTCTAAGCTGATATACAATAGGGTCATC
GCTTCCCGATATAGACCTTT

Downstream 100 bases:

>100_bases
AATATAAAATAGGAGCAAATGATGGCATGGATGCAAAAGCAAAGTCACAGATTAGATTATTCTACAAAACTTATCTGCCG
TTACCATTGGCTATCTACTC

Product: cation diffusion facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MTQTSQYDFWVKLASRASVATALTLIIIKLLAWLYSGSASMLASLTDSFADALASIVNFIAIRYAIVPADQDHRYGHGKA
EPLASLAQSAFIMGSAFLLLFYGGERLITPAPVEYATLGVVVSVVAIALTLALVMLQKRALAATNSTVVEADSLHYKSDL
FLNAAVLLALVLSQYGWWWADGLFAVLIAFYIGHQAFGLGYRSIQALLDRELDEETRQQIKQIAKEDPRVQGLHDLRTRQ
AGKTVFIQFHLELDGNLSLNEAHSIADTTGLRVKAAFEDAEVIIHQDPVKLEE

Sequences:

>Translated_293_residues
MTQTSQYDFWVKLASRASVATALTLIIIKLLAWLYSGSASMLASLTDSFADALASIVNFIAIRYAIVPADQDHRYGHGKA
EPLASLAQSAFIMGSAFLLLFYGGERLITPAPVEYATLGVVVSVVAIALTLALVMLQKRALAATNSTVVEADSLHYKSDL
FLNAAVLLALVLSQYGWWWADGLFAVLIAFYIGHQAFGLGYRSIQALLDRELDEETRQQIKQIAKEDPRVQGLHDLRTRQ
AGKTVFIQFHLELDGNLSLNEAHSIADTTGLRVKAAFEDAEVIIHQDPVKLEE
>Mature_292_residues
TQTSQYDFWVKLASRASVATALTLIIIKLLAWLYSGSASMLASLTDSFADALASIVNFIAIRYAIVPADQDHRYGHGKAE
PLASLAQSAFIMGSAFLLLFYGGERLITPAPVEYATLGVVVSVVAIALTLALVMLQKRALAATNSTVVEADSLHYKSDLF
LNAAVLLALVLSQYGWWWADGLFAVLIAFYIGHQAFGLGYRSIQALLDRELDEETRQQIKQIAKEDPRVQGLHDLRTRQA
GKTVFIQFHLELDGNLSLNEAHSIADTTGLRVKAAFEDAEVIIHQDPVKLEE

Specific function: Cation-efflux transporter that may have a role in detoxification [H]

COG id: COG0053

COG function: function code P; Predicted Co/Zn/Cd cation transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily [H]

Homologues:

Organism=Homo sapiens, GI57164948, Length=252, Percent_Identity=26.984126984127, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1790349, Length=267, Percent_Identity=49.063670411985, Blast_Score=262, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI115533508, Length=270, Percent_Identity=24.0740740740741, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115533506, Length=270, Percent_Identity=24.0740740740741, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 32137; Mature: 32006

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTSQYDFWVKLASRASVATALTLIIIKLLAWLYSGSASMLASLTDSFADALASIVNFI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AIRYAIVPADQDHRYGHGKAEPLASLAQSAFIMGSAFLLLFYGGERLITPAPVEYATLGV
HHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCEEECCCCHHHHHHHH
VVSVVAIALTLALVMLQKRALAATNSTVVEADSLHYKSDLFLNAAVLLALVLSQYGWWWA
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
DGLFAVLIAFYIGHQAFGLGYRSIQALLDRELDEETRQQIKQIAKEDPRVQGLHDLRTRQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHC
AGKTVFIQFHLELDGNLSLNEAHSIADTTGLRVKAAFEDAEVIIHQDPVKLEE
CCCEEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCC
>Mature Secondary Structure 
TQTSQYDFWVKLASRASVATALTLIIIKLLAWLYSGSASMLASLTDSFADALASIVNFI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AIRYAIVPADQDHRYGHGKAEPLASLAQSAFIMGSAFLLLFYGGERLITPAPVEYATLGV
HHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCEEECCCCHHHHHHHH
VVSVVAIALTLALVMLQKRALAATNSTVVEADSLHYKSDLFLNAAVLLALVLSQYGWWWA
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
DGLFAVLIAFYIGHQAFGLGYRSIQALLDRELDEETRQQIKQIAKEDPRVQGLHDLRTRQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHC
AGKTVFIQFHLELDGNLSLNEAHSIADTTGLRVKAAFEDAEVIIHQDPVKLEE
CCCEEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA