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The map label for this gene is rpoC [H]

Identifier: 120596983

GI number: 120596983

Start: 181261

End: 185478

Strand: Direct

Name: rpoC [H]

Synonym: Sputw3181_0150

Alternate gene names: 120596983

Gene position: 181261-185478 (Clockwise)

Preceding gene: 120596982

Following gene: 120596984

Centisome position: 3.85

GC content: 47.91

Gene sequence:

>4218_bases
GTGAAAGACTTATTAAAGTTTCTGAAACAGCAAAGCAAGACTGAAGAATTTAACGGCATCAAAATTGGTCTGGCATCGCC
TGATCTGATCCGTTCTTGGTCTTTTGGTGAAGTTAAGAAGCCAGAAACCATCAACTACCGTACCTTCAAGCCTGAGCGTG
AAGGTCTGTTCTGTGCGCGTATCTTTGGCCCAGTCAAAGATTACGAATGTTTGTGCGGTAAGTACAAACGTCTGAAGCAC
CGTGGTGTTATTTGTGAAAAGTGTGGCGTTGAAGTCACCCAGACTAAAGTACGTCGTGAGCGTATGGGTCACATCGAACT
GGCTAGCCCAGTCGCGCACATTTGGTTCTTAAAATCACTGCCGTCCCGTATCGGTTTAATGCTCGATATGACGCTGCGTG
ATATCGAACGCGTACTGTATTTTGAATCATTCGTCGTGATCGAGCCTGGCATGACCAGCCTTGAACGTGGTCAAATGCTG
ACAGAAGAAACGTATCTGGATGCGTTAGAAGAATACGGTGATGAGTTCGAAGCGAAAATGGGTGCCGAAGCTGTTCTAGA
ACTGCTGCGCGCTATCGATTTAGCGAAAGAAATCGAACAAATGCGTGAAGAATTACCTTCAATCAACTCTGAGACTCGTC
GCAAGAAAGTGACTAAACGTCTTAAGTTGATGGAAGCCTTCTTCACTTCAGGCAACAAGCCTGAATGGATGATCTTAAAA
GTACTGCCTGTGTTACCGCCTGACTTACGTCCGCTGGTACCGCTCGATGGCGGCCGCTTCGCGACTTCAGATCTTAACGA
CCTGTATCGCCGCGTGATCAACCGTAACAACCGTTTGAAGCGTCTGTTAGATTTAGCTGCGCCAGACATTATCGTACGCA
ACGAAAAGCGTATGTTACAAGAGTCTGTTGATGCGCTATTAGATAACGGTCGTCGTGGTCGTGCAATTACCGGTTCTAAC
AAGCGTCCTCTGAAATCTTTGGCCGATATGATCAAAGGTAAACAAGGTCGTTTCCGTCAGAACTTGTTGGGTAAACGCGT
TGACTATTCTGGTCGTTCGGTCATTACCGTCGGTCCTACTTTACGTCTGCACCAATGTGGTCTTCCTAAGAAGATGGCAC
TGGAACTGTTCAAACCATTTATCTATGGCAAGCTGGAAGGTCGTGGCTTAGCGACTACCATCAAAGCGGCTAAGAAGATG
GTTGAGCGTGAAGTGGCGGAAGTTTGGGACGTTCTGGATGAAGTGATCCGCGAACATCCAGTAATGCTTAACCGTGCACC
AACACTGCACAGATTAGGTATTCAAGCGTTCGAACCTGTACTGATTGAAGGTAAAGCCATCCAGTTACACCCACTCGTTT
GTGCGGCATACAACGCCGACTTCGACGGTGACCAAATGGCGGTACACGTACCGTTAACACTGGAAGCGCAGCTTGAAGCC
CGTGCCCTGATGATGTCTACCAACAACATCCTGTCACCCGCGAACGGCGAGCCTGTTATCACCCCGTCTCAAGACGTGGT
ATTGGGTCTGTACTACACCAGCCGTGAGCGTATTAACGGCCGTGGTGAAGGTATGGCATTTATGTCTGTTGCTGAAGTTG
AAAAAGCTTACGCAACTGGCGCTGCTGAACTGCATGCCCGCGTTAAAGTTCGTATCACTGAAACCATTATTGGTGATGAT
GGTGAGCGCACTGAACAACGCCGTATCGTTGATACGACTGTGGGTCGTGCTCTGCTGTCACTTATTCTGCCAGCAGGTTT
GTCATTTGATCTGGTTAACCAGAACATGGGCAAAAAGCAGATCTCTAAACTGTTGAACACCTGTTATCGTCAACTGGGTC
TGAAAGATACTGTTATCTTCGCTGACCAATTGATGTATACCGGTTTCCGTTTTGCAACCATCTCTGGTGCCTCTGTCGGT
ATCGATGACATGGTTATTCCAGACGAGAAATACACCTTAGTTGCTGATGCAGAAGCTGAAGTTCTTGAAATTCAAGAGCA
GTTCCAATCTGGTCTAGTCACAGCCGGTGAGCGTTACAACAAAGTTATCGATATCTGGGCAAGTGCCAACGAAAAAGTTT
CTAAAGCTATGATGGAAAACCTGTCAACTGAGACAGTGATTAACCGTGATGGCGTTGAAGAGAAACAAGCCTCGTTTAAC
AGCATCTATATGATGGCTGACTCAGGCGCTCGTGGTAGTGCTGCACAGATCCGTCAGTTGGCGGGTATGCGTGGTCTGAT
GGCGAAACCTGACGGCTCAATCATCGAAACGCCAATTACCGCTAACTTCCGTGAAGGTCTAAACGTACTCCAGTACTTTA
TTTCTACTCACGGTGCGCGTAAAGGTCTTGCCGATACTGCATTGAAAACAGCGAACTCGGGTTACCTGACTCGTCGTCTT
GTAGACGTTGCACAAGATTTAGTGGTTATCGAAGACGATTGTGGTACTCACGAAGGTCTAACCATGAAACCGCTGATTGA
AGGTGGTGATGTGGTTGAGCCGTTACGTGAACGCGTACTGGGTCGTGTGGTTGCCGTTGATGTGTTCTATCCAGGCACCG
AAGATGTACTAGCACCACGTAACACGCTGCTCGATGAAGCATGGTGTGACAAGTTAGAAGAGCATTCAATCGATGAAGTG
ATTGTGCGTTCTGTGATTACCTGTGATACCGATTTCGGTGTCTGTGCAGCCTGTTATGGACGTGACTTGGCCCGTGGTCA
TATCATCAACCATGGTGAGGCCATCGGTGTTGTGGCAGCACAATCTATCGGTGAACCAGGTACACAGTTAACGATGCGTA
CGTTCCACATCGGTGGTGCGGCATCTCGTGCGTCTGCAGAAAACAATGTCCAAGTGAAAAACTCGGGTTCATTGAAACTG
CATAATGCTAAGCATGTTACTAACAGCGACGGCAAACTGGTTATCGTTTCTCGTTCTTCTGAGCTGGCCATCATCGATGA
GTTAGGTCGTGAGAAAGAGCGTTACAAAGTGCCATACGGTACTGTGCTTGAGAAATTGGAAGAAGCTGCGGTTGAAGCGG
GCGATATTATCGCTAACTGGGATCCACATACTCACCCAATCATTTCTGAAGTGGCGGGTAGTATCAAGTTCGTCGATATG
ATTGACGGTGTCACTATGACACGTCAAACAGACGAACTAACGGGTCTATCATCAATCGTGATCCTTGACGTCGGTCAGCG
TGGTACAGCGGGTAAAGAAATGCGCCCAATGATCCGTCTGCTTGGCGCTAATGGTAGCGATCTGATGATCCCTGGTACAG
AAGTGCCAGCACAGTACTTCTTACCTGGTAGTGCGATTGTTAACCTTGACGACAACGCGCAAATTGCCGTAGGTGACGCT
TTAGCACGTATTCCACAGGAATCGTCTAAAACACGCGACATCACCGGTGGTCTGCCACGCGTTGCTGACCTGTTCGAAGC
GCGTAAGCCAAAAGAGCCTGCTATTCTGGCAGAAATCTCTGGTACCATCTCGTTTGGTAAAGAGACCAAAGGTAAGCGTC
GTTTGGTCATTACACCTGCTGATGGCGGCGATCAATATGAAGAGATGATCCCTAAATGGCGTAACTTAAACGTGTTCGAA
GGTGAAAAAGTCGAACGTGGTGAAGTTATCGCTGACGGTCCAGAAGCGGCACATGACATTCTGCGTCTGCGCGGTATCCA
CAATGTAGCAAACTACATTGTGAACGAAGTTCAAGACGTTTACCGTCTGCAAGGCGTGAAGATCAACGATAAGCATATCG
AAGTCATCATCCGTCAAATGCTACGTAAGTGCTTGATCACTTCTGCGGGTGACACAGAGTTCTTAGAAGGTGAGCAAGTT
GAAGTGTCTCGCGTTAAGATCGCAAACCGCGAACTTATCGCACAGGGTAAAGTACCTGCGACCTTCGAACGTGAACTGCT
AGGTATTACTAAAGCGTCTCTGGCAACAGAATCGTTTATCTCTGCAGCGTCGTTCCAAGAAACTACGCGCGTACTGACTG
AAGCCGCCGTAGGTGGTAAGAGTGATCAACTACGTGGTCTGAAAGAAAACGTTATCGTTGGTCGTTTGATCCCAGCCGGT
ACAGGTTATGCTTATCACAAGACCCGCAATGATGCTCGCGCTAAGAAAGACGAGCCAGTTGTTGTGAATAAAGTCACTGC
TAGTGAAGCTGAACAGAACCTCGCTGATCTCTTAAACATGGCCGGTAGCCAAGATTAA

Upstream 100 bases:

>100_bases
AGTTGGATCAGGAATAAGCGTCGCCCAAAGGCAACGTTTGGCAACAGAATGGTACTCCGCAGTCGCGGAGTACCCGGTTT
AACTCCTTCAGGAGAGAAAC

Downstream 100 bases:

>100_bases
GTAATCAGTTTGTAACAAAAAGGCGCCAATGGCGCCTTTTTTATTGTAAAATGCCGCAAAAGTTGGCTATTTCTTGACAG
TCAGGCATTACCTTTCTAAA

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1405; Mature: 1405

Protein sequence:

>1405_residues
MKDLLKFLKQQSKTEEFNGIKIGLASPDLIRSWSFGEVKKPETINYRTFKPEREGLFCARIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSLPSRIGLMLDMTLRDIERVLYFESFVVIEPGMTSLERGQML
TEETYLDALEEYGDEFEAKMGAEAVLELLRAIDLAKEIEQMREELPSINSETRRKKVTKRLKLMEAFFTSGNKPEWMILK
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIYGKLEGRGLATTIKAAKKM
VEREVAEVWDVLDEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
RALMMSTNNILSPANGEPVITPSQDVVLGLYYTSRERINGRGEGMAFMSVAEVEKAYATGAAELHARVKVRITETIIGDD
GERTEQRRIVDTTVGRALLSLILPAGLSFDLVNQNMGKKQISKLLNTCYRQLGLKDTVIFADQLMYTGFRFATISGASVG
IDDMVIPDEKYTLVADAEAEVLEIQEQFQSGLVTAGERYNKVIDIWASANEKVSKAMMENLSTETVINRDGVEEKQASFN
SIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRL
VDVAQDLVVIEDDCGTHEGLTMKPLIEGGDVVEPLRERVLGRVVAVDVFYPGTEDVLAPRNTLLDEAWCDKLEEHSIDEV
IVRSVITCDTDFGVCAACYGRDLARGHIINHGEAIGVVAAQSIGEPGTQLTMRTFHIGGAASRASAENNVQVKNSGSLKL
HNAKHVTNSDGKLVIVSRSSELAIIDELGREKERYKVPYGTVLEKLEEAAVEAGDIIANWDPHTHPIISEVAGSIKFVDM
IDGVTMTRQTDELTGLSSIVILDVGQRGTAGKEMRPMIRLLGANGSDLMIPGTEVPAQYFLPGSAIVNLDDNAQIAVGDA
LARIPQESSKTRDITGGLPRVADLFEARKPKEPAILAEISGTISFGKETKGKRRLVITPADGGDQYEEMIPKWRNLNVFE
GEKVERGEVIADGPEAAHDILRLRGIHNVANYIVNEVQDVYRLQGVKINDKHIEVIIRQMLRKCLITSAGDTEFLEGEQV
EVSRVKIANRELIAQGKVPATFERELLGITKASLATESFISAASFQETTRVLTEAAVGGKSDQLRGLKENVIVGRLIPAG
TGYAYHKTRNDARAKKDEPVVVNKVTASEAEQNLADLLNMAGSQD

Sequences:

>Translated_1405_residues
MKDLLKFLKQQSKTEEFNGIKIGLASPDLIRSWSFGEVKKPETINYRTFKPEREGLFCARIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSLPSRIGLMLDMTLRDIERVLYFESFVVIEPGMTSLERGQML
TEETYLDALEEYGDEFEAKMGAEAVLELLRAIDLAKEIEQMREELPSINSETRRKKVTKRLKLMEAFFTSGNKPEWMILK
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIYGKLEGRGLATTIKAAKKM
VEREVAEVWDVLDEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
RALMMSTNNILSPANGEPVITPSQDVVLGLYYTSRERINGRGEGMAFMSVAEVEKAYATGAAELHARVKVRITETIIGDD
GERTEQRRIVDTTVGRALLSLILPAGLSFDLVNQNMGKKQISKLLNTCYRQLGLKDTVIFADQLMYTGFRFATISGASVG
IDDMVIPDEKYTLVADAEAEVLEIQEQFQSGLVTAGERYNKVIDIWASANEKVSKAMMENLSTETVINRDGVEEKQASFN
SIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRL
VDVAQDLVVIEDDCGTHEGLTMKPLIEGGDVVEPLRERVLGRVVAVDVFYPGTEDVLAPRNTLLDEAWCDKLEEHSIDEV
IVRSVITCDTDFGVCAACYGRDLARGHIINHGEAIGVVAAQSIGEPGTQLTMRTFHIGGAASRASAENNVQVKNSGSLKL
HNAKHVTNSDGKLVIVSRSSELAIIDELGREKERYKVPYGTVLEKLEEAAVEAGDIIANWDPHTHPIISEVAGSIKFVDM
IDGVTMTRQTDELTGLSSIVILDVGQRGTAGKEMRPMIRLLGANGSDLMIPGTEVPAQYFLPGSAIVNLDDNAQIAVGDA
LARIPQESSKTRDITGGLPRVADLFEARKPKEPAILAEISGTISFGKETKGKRRLVITPADGGDQYEEMIPKWRNLNVFE
GEKVERGEVIADGPEAAHDILRLRGIHNVANYIVNEVQDVYRLQGVKINDKHIEVIIRQMLRKCLITSAGDTEFLEGEQV
EVSRVKIANRELIAQGKVPATFERELLGITKASLATESFISAASFQETTRVLTEAAVGGKSDQLRGLKENVIVGRLIPAG
TGYAYHKTRNDARAKKDEPVVVNKVTASEAEQNLADLLNMAGSQD
>Mature_1405_residues
MKDLLKFLKQQSKTEEFNGIKIGLASPDLIRSWSFGEVKKPETINYRTFKPEREGLFCARIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSLPSRIGLMLDMTLRDIERVLYFESFVVIEPGMTSLERGQML
TEETYLDALEEYGDEFEAKMGAEAVLELLRAIDLAKEIEQMREELPSINSETRRKKVTKRLKLMEAFFTSGNKPEWMILK
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIYGKLEGRGLATTIKAAKKM
VEREVAEVWDVLDEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
RALMMSTNNILSPANGEPVITPSQDVVLGLYYTSRERINGRGEGMAFMSVAEVEKAYATGAAELHARVKVRITETIIGDD
GERTEQRRIVDTTVGRALLSLILPAGLSFDLVNQNMGKKQISKLLNTCYRQLGLKDTVIFADQLMYTGFRFATISGASVG
IDDMVIPDEKYTLVADAEAEVLEIQEQFQSGLVTAGERYNKVIDIWASANEKVSKAMMENLSTETVINRDGVEEKQASFN
SIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRL
VDVAQDLVVIEDDCGTHEGLTMKPLIEGGDVVEPLRERVLGRVVAVDVFYPGTEDVLAPRNTLLDEAWCDKLEEHSIDEV
IVRSVITCDTDFGVCAACYGRDLARGHIINHGEAIGVVAAQSIGEPGTQLTMRTFHIGGAASRASAENNVQVKNSGSLKL
HNAKHVTNSDGKLVIVSRSSELAIIDELGREKERYKVPYGTVLEKLEEAAVEAGDIIANWDPHTHPIISEVAGSIKFVDM
IDGVTMTRQTDELTGLSSIVILDVGQRGTAGKEMRPMIRLLGANGSDLMIPGTEVPAQYFLPGSAIVNLDDNAQIAVGDA
LARIPQESSKTRDITGGLPRVADLFEARKPKEPAILAEISGTISFGKETKGKRRLVITPADGGDQYEEMIPKWRNLNVFE
GEKVERGEVIADGPEAAHDILRLRGIHNVANYIVNEVQDVYRLQGVKINDKHIEVIIRQMLRKCLITSAGDTEFLEGEQV
EVSRVKIANRELIAQGKVPATFERELLGITKASLATESFISAASFQETTRVLTEAAVGGKSDQLRGLKENVIVGRLIPAG
TGYAYHKTRNDARAKKDEPVVVNKVTASEAEQNLADLLNMAGSQD

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=924, Percent_Identity=26.4069264069264, Blast_Score=210, Evalue=8e-54,
Organism=Homo sapiens, GI39725938, Length=684, Percent_Identity=26.1695906432749, Blast_Score=157, Evalue=5e-38,
Organism=Homo sapiens, GI103471997, Length=225, Percent_Identity=31.1111111111111, Blast_Score=91, Evalue=1e-17,
Organism=Escherichia coli, GI2367335, Length=1407, Percent_Identity=80.3837953091684, Blast_Score=2328, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=685, Percent_Identity=27.7372262773723, Blast_Score=189, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI71987878, Length=919, Percent_Identity=24.4831338411317, Blast_Score=177, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6324690, Length=699, Percent_Identity=26.0371959942775, Blast_Score=169, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6320061, Length=537, Percent_Identity=26.2569832402235, Blast_Score=147, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6324917, Length=381, Percent_Identity=25.1968503937008, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17530899, Length=929, Percent_Identity=25.0807319698601, Blast_Score=188, Evalue=2e-47,
Organism=Drosophila melanogaster, GI281360912, Length=882, Percent_Identity=23.5827664399093, Blast_Score=167, Evalue=4e-41,
Organism=Drosophila melanogaster, GI17647875, Length=377, Percent_Identity=27.5862068965517, Blast_Score=103, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 155301; Mature: 155301

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLLKFLKQQSKTEEFNGIKIGLASPDLIRSWSFGEVKKPETINYRTFKPEREGLFCAR
CHHHHHHHHHHCCCCCCCCEEEECCCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHH
PSRIGLMLDMTLRDIERVLYFESFVVIEPGMTSLERGQMLTEETYLDALEEYGDEFEAKM
HHHHCHHHHHHHHHHHHHHHHHCEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHC
GAEAVLELLRAIDLAKEIEQMREELPSINSETRRKKVTKRLKLMEAFFTSGNKPEWMILK
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQ
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHHHH
ESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPT
HHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCC
LRLHQCGLPKKMALELFKPFIYGKLEGRGLATTIKAAKKMVEREVAEVWDVLDEVIREHP
EEECCCCCCHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
CEECCCCCHHHHCHHHCCCEEECCCEEEEECEEEEEECCCCCCCCEEEEEEEEEECCHHH
RALMMSTNNILSPANGEPVITPSQDVVLGLYYTSRERINGRGEGMAFMSVAEVEKAYATG
HHHEEECCCCCCCCCCCEEECCCCCEEEEEEEECHHHCCCCCCCEEHHHHHHHHHHHHCC
AAELHARVKVRITETIIGDDGERTEQRRIVDTTVGRALLSLILPAGLSFDLVNQNMGKKQ
HHHEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHCCCCCHHH
ISKLLNTCYRQLGLKDTVIFADQLMYTGFRFATISGASVGIDDMVIPDEKYTLVADAEAE
HHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCEECCCCCEEEEECCCHH
VLEIQEQFQSGLVTAGERYNKVIDIWASANEKVSKAMMENLSTETVINRDGVEEKQASFN
HHHHHHHHHCCCCCCCHHHCCEEEEECCCCHHHHHHHHHCCCHHHEECCCCCCHHHCCCC
SIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGAR
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCC
KGLADTALKTANSGYLTRRLVDVAQDLVVIEDDCGTHEGLTMKPLIEGGDVVEPLRERVL
CCHHHHHHHHCCCCHHHHHHHHHHHCEEEEECCCCCCCCCEECCCCCCCCHHHHHHHHHH
GRVVAVDVFYPGTEDVLAPRNTLLDEAWCDKLEEHSIDEVIVRSVITCDTDFGVCAACYG
HEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHC
RDLARGHIINHGEAIGVVAAQSIGEPGTQLTMRTFHIGGAASRASAENNVQVKNSGSLKL
CHHHCCCEECCCCEEEEEEHHHCCCCCCEEEEEEEEECCCCCCCCCCCCEEEECCCCEEE
HNAKHVTNSDGKLVIVSRSSELAIIDELGREKERYKVPYGTVLEKLEEAAVEAGDIIANW
ECCCCEECCCCEEEEEECCCCEEHHHHHCCCHHHEECCHHHHHHHHHHHHHCCCCEEECC
DPHTHPIISEVAGSIKFVDMIDGVTMTRQTDELTGLSSIVILDVGQRGTAGKEMRPMIRL
CCCCCHHHHHHCCCEEEEHHHCCCEEECCCHHHCCCCEEEEEECCCCCCCCHHHHHHHHH
LGANGSDLMIPGTEVPAQYFLPGSAIVNLDDNAQIAVGDALARIPQESSKTRDITGGLPR
HCCCCCEEEECCCCCCHHEECCCCEEEEECCCCEEEECHHHHHCCCCCCCCCCCCCCCHH
VADLFEARKPKEPAILAEISGTISFGKETKGKRRLVITPADGGDQYEEMIPKWRNLNVFE
HHHHHHHCCCCCCEEEEEECCCEECCCCCCCCEEEEEEECCCCHHHHHHCCHHCCCCCCC
GEKVERGEVIADGPEAAHDILRLRGIHNVANYIVNEVQDVYRLQGVKINDKHIEVIIRQM
CCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHH
LRKCLITSAGDTEFLEGEQVEVSRVKIANRELIAQGKVPATFERELLGITKASLATESFI
HHHHHCCCCCCCCCCCCCCEEEHHEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
SAASFQETTRVLTEAAVGGKSDQLRGLKENVIVGRLIPAGTGYAYHKTRNDARAKKDEPV
HHHHHHHHHHHHHHHHCCCCHHHHCCHHHCCEEEEEECCCCCCEEECCCCHHCCCCCCCE
VVNKVTASEAEQNLADLLNMAGSQD
EEEECCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKDLLKFLKQQSKTEEFNGIKIGLASPDLIRSWSFGEVKKPETINYRTFKPEREGLFCAR
CHHHHHHHHHHCCCCCCCCEEEECCCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHH
PSRIGLMLDMTLRDIERVLYFESFVVIEPGMTSLERGQMLTEETYLDALEEYGDEFEAKM
HHHHCHHHHHHHHHHHHHHHHHCEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHC
GAEAVLELLRAIDLAKEIEQMREELPSINSETRRKKVTKRLKLMEAFFTSGNKPEWMILK
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQ
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHHHH
ESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPT
HHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCC
LRLHQCGLPKKMALELFKPFIYGKLEGRGLATTIKAAKKMVEREVAEVWDVLDEVIREHP
EEECCCCCCHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
CEECCCCCHHHHCHHHCCCEEECCCEEEEECEEEEEECCCCCCCCEEEEEEEEEECCHHH
RALMMSTNNILSPANGEPVITPSQDVVLGLYYTSRERINGRGEGMAFMSVAEVEKAYATG
HHHEEECCCCCCCCCCCEEECCCCCEEEEEEEECHHHCCCCCCCEEHHHHHHHHHHHHCC
AAELHARVKVRITETIIGDDGERTEQRRIVDTTVGRALLSLILPAGLSFDLVNQNMGKKQ
HHHEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHCCCCCHHH
ISKLLNTCYRQLGLKDTVIFADQLMYTGFRFATISGASVGIDDMVIPDEKYTLVADAEAE
HHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCEECCCCCEEEEECCCHH
VLEIQEQFQSGLVTAGERYNKVIDIWASANEKVSKAMMENLSTETVINRDGVEEKQASFN
HHHHHHHHHCCCCCCCHHHCCEEEEECCCCHHHHHHHHHCCCHHHEECCCCCCHHHCCCC
SIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGAR
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCC
KGLADTALKTANSGYLTRRLVDVAQDLVVIEDDCGTHEGLTMKPLIEGGDVVEPLRERVL
CCHHHHHHHHCCCCHHHHHHHHHHHCEEEEECCCCCCCCCEECCCCCCCCHHHHHHHHHH
GRVVAVDVFYPGTEDVLAPRNTLLDEAWCDKLEEHSIDEVIVRSVITCDTDFGVCAACYG
HEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHC
RDLARGHIINHGEAIGVVAAQSIGEPGTQLTMRTFHIGGAASRASAENNVQVKNSGSLKL
CHHHCCCEECCCCEEEEEEHHHCCCCCCEEEEEEEEECCCCCCCCCCCCEEEECCCCEEE
HNAKHVTNSDGKLVIVSRSSELAIIDELGREKERYKVPYGTVLEKLEEAAVEAGDIIANW
ECCCCEECCCCEEEEEECCCCEEHHHHHCCCHHHEECCHHHHHHHHHHHHHCCCCEEECC
DPHTHPIISEVAGSIKFVDMIDGVTMTRQTDELTGLSSIVILDVGQRGTAGKEMRPMIRL
CCCCCHHHHHHCCCEEEEHHHCCCEEECCCHHHCCCCEEEEEECCCCCCCCHHHHHHHHH
LGANGSDLMIPGTEVPAQYFLPGSAIVNLDDNAQIAVGDALARIPQESSKTRDITGGLPR
HCCCCCEEEECCCCCCHHEECCCCEEEEECCCCEEEECHHHHHCCCCCCCCCCCCCCCHH
VADLFEARKPKEPAILAEISGTISFGKETKGKRRLVITPADGGDQYEEMIPKWRNLNVFE
HHHHHHHCCCCCCEEEEEECCCEECCCCCCCCEEEEEEECCCCHHHHHHCCHHCCCCCCC
GEKVERGEVIADGPEAAHDILRLRGIHNVANYIVNEVQDVYRLQGVKINDKHIEVIIRQM
CCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHH
LRKCLITSAGDTEFLEGEQVEVSRVKIANRELIAQGKVPATFERELLGITKASLATESFI
HHHHHCCCCCCCCCCCCCCEEEHHEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
SAASFQETTRVLTEAAVGGKSDQLRGLKENVIVGRLIPAGTGYAYHKTRNDARAKKDEPV
HHHHHHHHHHHHHHHHCCCCHHHHCCHHHCCEEEEEECCCCCCEEECCCCHHCCCCCCCE
VVNKVTASEAEQNLADLLNMAGSQD
EEEECCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA