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The map label for this gene is rpoB

Identifier: 120596982

GI number: 120596982

Start: 177146

End: 181177

Strand: Direct

Name: rpoB

Synonym: Sputw3181_0149

Alternate gene names: 120596982

Gene position: 177146-181177 (Clockwise)

Preceding gene: 120596981

Following gene: 120596983

Centisome position: 3.76

GC content: 46.53

Gene sequence:

>4032_bases
ATGGTTTACTCCTATTCTGAAAAGAAGCGTATTCGCAAAGACTTTGGTAAGCGTCCACAGGTGTTGGATATTCCTTACCT
TTTGTCTATTCAGTTAGACTCTTTTAAGAAGTTCACCGATCAAGATCCTACCGGTGAGCGCGGTCTTGAAGCCGCCTTCC
GTAGCGTTTTTCCCATCAAGAGCTTTTCTGGTAATTCAGAACTGCAATACGTCAGCTATAAGCTTGGCGAGCCTGTTTTT
GATGTGAAAGAGTGTCAGATCCGCGGTGTTACGTATTCAGCACCACTACGCGTTAAATTACGCATGGTGTTGTATGACCG
TGAAGCAGCGGCAGGCACTGTAAAAGATATTAAAGAGCAAGAAGTCTACATGGGCGATATCCCATTGATGACGGATAACG
GTACCTTTGTTATCAACGGTACTGAGCGTGTAATCGTATCTCAATTACACCGTAGCCCTGGCGTGTTCTTCGATCATGAC
CGTGGTAAAACCCACTCATCGGGTAAGGTGCTGTATAACGCACGTATTATTCCTTACCGTGGTTCATGGCTTGACTTTGA
ATTCGATCCTAAAGATGCACTTTTCGTACGTATTGACCGTCGCCGTAAATTACCAGCGACCATCATTCTGCGTGCATTAG
AATACTCTACTCAAGAGATCCTCGACCTGTTCTTCGAACGTGTTGAGTTCAAGATCAAGAAAGATACGTTAGTCATGGCG
TTAGTTCCTGAGCGTCTGCGTGGCGAAACTGCCAGCTATGACATCAAGGATGCTGAAGGTTCTGTGCTGGTTGAAGCGGG
CCGTCGTATTACTGCGCGCCATATTCGCCAGTTAGAAAAGACTAATACCACTGAACTCGAAGTGCCAGTTGAATATATCG
TGGGCAAATATGCTGCTCAAGATTATATCGATCCGGACACGGGTGAAGTTTTAGTATCTGCAAACAGTGAAATCAGCTTA
GAAGACTTAGCGAAATTATCACTGGCTGGCATTAAAGATATCAGCACGTTGTATATCAACGAGCTAGATCATGGTGCTTA
TATTTCAGATACGCTGCGTATCGATTCAACCACTAACCGCTTAGAAGCGCTGGTTGAAATCTATCGTATGATGCGTCCTG
GCGAGCCACCAACCAAAGATGCGGCAGAAGCACTATTCCAGAACTTGTTCTTCAGTGAAGAACGCTATGACCTGTCTAAA
GTCGGTCGTATGAAGTTCAACCGTCGTCTGAGCATCCCCGATGACGAAGGTAGCGGTGTATTGTCTAAAGAAGACATCGT
CGCGGTAATGAAGAACATCATTCATATCCGTAACGGTTTCGACGAAGTCGATGACATCGATCACTTAGGTAACCGTCGTA
TTCGTAGCGTCGGTGAAATGGCTGAAAACCAATTCCGTGTTGGTTTAGTCCGTGTTGAGCGCGCTGTGCGTGAACGTCTA
TCTTTAGGCGATCTGAACGAGCTGATGCCACAAGACTTAATCAACGCTAAGCCAATTTCTGCTGCAGTGAAAGAGTTCTT
CGGTTCTTCACAGCTGTCACAATTCATGGACCAAAACAACCCGCTGTCAGAAGTCACGCATAAGCGTCGTATTTCTGCTC
TTGGCCCTGGTGGTTTGACTCGTGAACGTGCAGGCTTTGAAGTCCGTGACGTACATCCAACGCATTATGGTCGTTTATGT
CCAATTGAGACCCCTGAAGGTCCAAACATTGGTCTAATCAACTCATTAGCAAGTTTTGCCCGTACTAACTCATACGGCTT
CTTAGAAACGCCATACCGCAAGGTGATTGATGGCGTGATTACTGACGAAGTGGAATACTTGTCAGCGATTGAAGAAGGTC
GTTATGTCATTGCACAGGCAAACATCGAAGTTGATGCAAATGGCCGCATGGTTGAAGAGCAGATCGCCTGTCGTCATAAA
GGTGAATCTACCTTTATGCGCGCATCTGATATTCAATACATGGACGTATCGCCACAACAGATTATTTCTGTTGCTGCATC
ACTGATCCCGTTCTTAGAACACGACGACGCTAACCGTGCATTGATGGGTGCGAACATGCAACGTCAAGCCGTACCCACAC
TGCGCTCTGAAAAGCCATTAGTCGGTACTGGTATTGAACGTACGCTAGCTGTTGATTCTGGTGTTGTAGTTGTTGCTAAG
CGTGGTGGTTATATCGACTACGTTGATGCGAGCCGTATCGTTGTTAAAGTCAATGAAGATGAGCTACGTCCAGGCGAAGC
GGGTATCGACATTTATAACCTGACTAAATACACCCGGTCTAACCAAAATACTTGTATCAACCAGCGCCCTTGTTGTGCCG
TTGGTGAGCCAGTCGTTCGTGGTGACGTGTTAGCAGACGGTCCGTCTACTGACTTAGGTGACTTAGCTCTTGGCCAGAAC
ATGCGCATCGCGTTCATGCCTTGGAACGGTTACAACTTCGAAGACTCGATCTTAATTTCTGAGCGCGTAGCACAGGAAGA
CCGTTTCACCACTATCCACATCCAAGAGCTGTCTTGTATTGCTCGTGATACCAAACTGGGTAGCGAAGAAATCACCGCTG
ATATTCCAAACGTAGGTGAATCTGCTCTGTCGAAACTCGACGAATCAGGTATCGTTTATATTGGTGCAGAAGTGAAGGGT
GGCGATATTCTGGTCGGTAAAGTGACGCCAAAAGGCGAAACTCAGCTAACACCAGAAGAGAAGTTACTCCGTGCTATCTT
CGGTGAGAAAGCGTCTGATGTGAAAGACAGCTCACTGCGTGTACCTAACTCTGTTAAGGGCACTATCATCGACGTTCAGG
TATTTACCCGTGACGGCGTTGAAAAAGATAAACGTGCAGTTGAAATCGAAGAGATGCACATCGCTCAAGCACGTAAAGAC
TTAAGCGAAGAGTTCAAGATCCTTGAAGAAGGTGTATTGAGCCGTGCTCGTAACCTATTGTTAGGTGCAGGTTTCACAGA
AACACAAATCGCAGCGATGCCACGTAAGGATGTATTGGTTCAAGTTATTGACGATGAAGCAAAACAAACTGAACTTGAGC
AATTAGCTGAGCAGCATGAAGAGCTGAAAGCAGACTTCGATAAGAAGTTTGAAATTAAACGTCGCAAGATCACCCAAGGT
GATGACTTGGCGCCAGGCGTACTGAAGATCGTTAAGGTTTACTTAGCGGTTAAGCGTACTATCCAACCTGGTGACAAGAT
GGCGGGTCGTCATGGTAACAAAGGTGTTATCTCTAAGATTTGCCCAATCGAAGACATGCCATATGACGAACAAGGTAATC
CAGTAGACATCGTATTGAACCCACTAGGTGTTCCGTCACGGATGAACATTGGTCAGGTACTTGAAGTCCATATGGGCGCC
GCCGCTAAAGGTATTGGTAACAAGATCACTGCAATGCTTGAAGAACAGCGCGAGCTGGCTGAAGTACGCGGTTACATCAA
ACAAGTGTATGAGTTAGGTGACGAAGTGCAGCAGCGCGTCGATATCGATTCATTCACCGATGATGAAGTGATGCGTCTTG
CCCAAAACTTGAAGGGTGGTATCCCGATTGCGACTCCTGCATTCGACGGTGCTAAAGAGAAAGAGATCAAGCAGATGCTT
GAGCTTGCAGGCTTGCCAACCTCTGGTCAGCTGAAGTTGTATGATGGTCGTACCGGTAACGAATTTGAGCGTCAAGTAAC
CGTTGGTTACATGTACATGCTCAAACTGAACCACTTAGTTGATGACAAGATGCACGCCCGTTCTACCGGTTCGTACAGCT
TAGTGACTCAACAACCACTGGGCGGTAAAGCTCAGTTCGGTGGTCAGCGTTTCGGTGAGATGGAAGTGTGGGCACTAGAA
GCATACGGTGCCGCTTATACGCTTCAAGAAATGCTCACTGTGAAATCGGATGACGTTAACGGTCGTACTCAGATGTATAA
GAACATCGTCGACGGTAACCATCAGATGCAACCTGGCATGCCAGAGTCCTTCAACGTGTTACTGAAGGAGATCCGTTCAC
TCGGTATTAATATCGAGTTGGATCAGGAATAA

Upstream 100 bases:

>100_bases
GTTAGGTTCTTGCCATCAACGGTGATGGGCAAACGTGCTGAATGTAATAACTTAAGTTATTGATTCAGTCTTGGTCACAT
CTCGTAAGCAGAGGAAACCC

Downstream 100 bases:

>100_bases
GCGTCGCCCAAAGGCAACGTTTGGCAACAGAATGGTACTCCGCAGTCGCGGAGTACCCGGTTTAACTCCTTCAGGAGAGA
AACGTGAAAGACTTATTAAA

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1343; Mature: 1343

Protein sequence:

>1343_residues
MVYSYSEKKRIRKDFGKRPQVLDIPYLLSIQLDSFKKFTDQDPTGERGLEAAFRSVFPIKSFSGNSELQYVSYKLGEPVF
DVKECQIRGVTYSAPLRVKLRMVLYDREAAAGTVKDIKEQEVYMGDIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDHD
RGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDALFVRIDRRRKLPATIILRALEYSTQEILDLFFERVEFKIKKDTLVMA
LVPERLRGETASYDIKDAEGSVLVEAGRRITARHIRQLEKTNTTELEVPVEYIVGKYAAQDYIDPDTGEVLVSANSEISL
EDLAKLSLAGIKDISTLYINELDHGAYISDTLRIDSTTNRLEALVEIYRMMRPGEPPTKDAAEALFQNLFFSEERYDLSK
VGRMKFNRRLSIPDDEGSGVLSKEDIVAVMKNIIHIRNGFDEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVRERL
SLGDLNELMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRLC
PIETPEGPNIGLINSLASFARTNSYGFLETPYRKVIDGVITDEVEYLSAIEEGRYVIAQANIEVDANGRMVEEQIACRHK
GESTFMRASDIQYMDVSPQQIISVAASLIPFLEHDDANRALMGANMQRQAVPTLRSEKPLVGTGIERTLAVDSGVVVVAK
RGGYIDYVDASRIVVKVNEDELRPGEAGIDIYNLTKYTRSNQNTCINQRPCCAVGEPVVRGDVLADGPSTDLGDLALGQN
MRIAFMPWNGYNFEDSILISERVAQEDRFTTIHIQELSCIARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVKG
GDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNSVKGTIIDVQVFTRDGVEKDKRAVEIEEMHIAQARKD
LSEEFKILEEGVLSRARNLLLGAGFTETQIAAMPRKDVLVQVIDDEAKQTELEQLAEQHEELKADFDKKFEIKRRKITQG
DDLAPGVLKIVKVYLAVKRTIQPGDKMAGRHGNKGVISKICPIEDMPYDEQGNPVDIVLNPLGVPSRMNIGQVLEVHMGA
AAKGIGNKITAMLEEQRELAEVRGYIKQVYELGDEVQQRVDIDSFTDDEVMRLAQNLKGGIPIATPAFDGAKEKEIKQML
ELAGLPTSGQLKLYDGRTGNEFERQVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALE
AYGAAYTLQEMLTVKSDDVNGRTQMYKNIVDGNHQMQPGMPESFNVLLKEIRSLGINIELDQE

Sequences:

>Translated_1343_residues
MVYSYSEKKRIRKDFGKRPQVLDIPYLLSIQLDSFKKFTDQDPTGERGLEAAFRSVFPIKSFSGNSELQYVSYKLGEPVF
DVKECQIRGVTYSAPLRVKLRMVLYDREAAAGTVKDIKEQEVYMGDIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDHD
RGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDALFVRIDRRRKLPATIILRALEYSTQEILDLFFERVEFKIKKDTLVMA
LVPERLRGETASYDIKDAEGSVLVEAGRRITARHIRQLEKTNTTELEVPVEYIVGKYAAQDYIDPDTGEVLVSANSEISL
EDLAKLSLAGIKDISTLYINELDHGAYISDTLRIDSTTNRLEALVEIYRMMRPGEPPTKDAAEALFQNLFFSEERYDLSK
VGRMKFNRRLSIPDDEGSGVLSKEDIVAVMKNIIHIRNGFDEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVRERL
SLGDLNELMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRLC
PIETPEGPNIGLINSLASFARTNSYGFLETPYRKVIDGVITDEVEYLSAIEEGRYVIAQANIEVDANGRMVEEQIACRHK
GESTFMRASDIQYMDVSPQQIISVAASLIPFLEHDDANRALMGANMQRQAVPTLRSEKPLVGTGIERTLAVDSGVVVVAK
RGGYIDYVDASRIVVKVNEDELRPGEAGIDIYNLTKYTRSNQNTCINQRPCCAVGEPVVRGDVLADGPSTDLGDLALGQN
MRIAFMPWNGYNFEDSILISERVAQEDRFTTIHIQELSCIARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVKG
GDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNSVKGTIIDVQVFTRDGVEKDKRAVEIEEMHIAQARKD
LSEEFKILEEGVLSRARNLLLGAGFTETQIAAMPRKDVLVQVIDDEAKQTELEQLAEQHEELKADFDKKFEIKRRKITQG
DDLAPGVLKIVKVYLAVKRTIQPGDKMAGRHGNKGVISKICPIEDMPYDEQGNPVDIVLNPLGVPSRMNIGQVLEVHMGA
AAKGIGNKITAMLEEQRELAEVRGYIKQVYELGDEVQQRVDIDSFTDDEVMRLAQNLKGGIPIATPAFDGAKEKEIKQML
ELAGLPTSGQLKLYDGRTGNEFERQVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALE
AYGAAYTLQEMLTVKSDDVNGRTQMYKNIVDGNHQMQPGMPESFNVLLKEIRSLGINIELDQE
>Mature_1343_residues
MVYSYSEKKRIRKDFGKRPQVLDIPYLLSIQLDSFKKFTDQDPTGERGLEAAFRSVFPIKSFSGNSELQYVSYKLGEPVF
DVKECQIRGVTYSAPLRVKLRMVLYDREAAAGTVKDIKEQEVYMGDIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDHD
RGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDALFVRIDRRRKLPATIILRALEYSTQEILDLFFERVEFKIKKDTLVMA
LVPERLRGETASYDIKDAEGSVLVEAGRRITARHIRQLEKTNTTELEVPVEYIVGKYAAQDYIDPDTGEVLVSANSEISL
EDLAKLSLAGIKDISTLYINELDHGAYISDTLRIDSTTNRLEALVEIYRMMRPGEPPTKDAAEALFQNLFFSEERYDLSK
VGRMKFNRRLSIPDDEGSGVLSKEDIVAVMKNIIHIRNGFDEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVRERL
SLGDLNELMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRLC
PIETPEGPNIGLINSLASFARTNSYGFLETPYRKVIDGVITDEVEYLSAIEEGRYVIAQANIEVDANGRMVEEQIACRHK
GESTFMRASDIQYMDVSPQQIISVAASLIPFLEHDDANRALMGANMQRQAVPTLRSEKPLVGTGIERTLAVDSGVVVVAK
RGGYIDYVDASRIVVKVNEDELRPGEAGIDIYNLTKYTRSNQNTCINQRPCCAVGEPVVRGDVLADGPSTDLGDLALGQN
MRIAFMPWNGYNFEDSILISERVAQEDRFTTIHIQELSCIARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVKG
GDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNSVKGTIIDVQVFTRDGVEKDKRAVEIEEMHIAQARKD
LSEEFKILEEGVLSRARNLLLGAGFTETQIAAMPRKDVLVQVIDDEAKQTELEQLAEQHEELKADFDKKFEIKRRKITQG
DDLAPGVLKIVKVYLAVKRTIQPGDKMAGRHGNKGVISKICPIEDMPYDEQGNPVDIVLNPLGVPSRMNIGQVLEVHMGA
AAKGIGNKITAMLEEQRELAEVRGYIKQVYELGDEVQQRVDIDSFTDDEVMRLAQNLKGGIPIATPAFDGAKEKEIKQML
ELAGLPTSGQLKLYDGRTGNEFERQVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALE
AYGAAYTLQEMLTVKSDDVNGRTQMYKNIVDGNHQMQPGMPESFNVLLKEIRSLGINIELDQE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI33469941, Length=260, Percent_Identity=33.0769230769231, Blast_Score=131, Evalue=6e-30,
Organism=Homo sapiens, GI212286172, Length=260, Percent_Identity=33.0769230769231, Blast_Score=130, Evalue=6e-30,
Organism=Homo sapiens, GI4505941, Length=304, Percent_Identity=29.2763157894737, Blast_Score=121, Evalue=5e-27,
Organism=Homo sapiens, GI238908505, Length=160, Percent_Identity=34.375, Blast_Score=82, Evalue=4e-15,
Organism=Homo sapiens, GI238908503, Length=160, Percent_Identity=34.375, Blast_Score=82, Evalue=4e-15,
Organism=Escherichia coli, GI1790419, Length=1343, Percent_Identity=80.4169769173492, Blast_Score=2254, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25144348, Length=302, Percent_Identity=29.4701986754967, Blast_Score=120, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17552304, Length=249, Percent_Identity=31.7269076305221, Blast_Score=119, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17506623, Length=234, Percent_Identity=31.1965811965812, Blast_Score=116, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6324781, Length=248, Percent_Identity=32.6612903225806, Blast_Score=124, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6325267, Length=252, Percent_Identity=32.5396825396825, Blast_Score=120, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6324725, Length=310, Percent_Identity=28.7096774193548, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17647877, Length=298, Percent_Identity=30.2013422818792, Blast_Score=122, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17136446, Length=259, Percent_Identity=33.2046332046332, Blast_Score=118, Evalue=4e-26,
Organism=Drosophila melanogaster, GI17136444, Length=249, Percent_Identity=31.3253012048193, Blast_Score=114, Evalue=3e-25,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 150215; Mature: 150215

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYSYSEKKRIRKDFGKRPQVLDIPYLLSIQLDSFKKFTDQDPTGERGLEAAFRSVFPIK
CCCCCHHHHHHHHHHCCCCCEEECCEEEEEEHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
SFSGNSELQYVSYKLGEPVFDVKECQIRGVTYSAPLRVKLRMVLYDREAAAGTVKDIKEQ
CCCCCCCEEEEEEECCCCCCCCCCEEEECEEECCCCEEEEEEEEEECCCCCCHHHHHHHH
EVYMGDIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKVLYNARIIPYR
HEEECCCEEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEEEEEC
GSWLDFEFDPKDALFVRIDRRRKLPATIILRALEYSTQEILDLFFERVEFKIKKDTLVMA
CCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHEEECCCEEEEE
LVPERLRGETASYDIKDAEGSVLVEAGRRITARHIRQLEKTNTTELEVPVEYIVGKYAAQ
ECCHHHCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHH
DYIDPDTGEVLVSANSEISLEDLAKLSLAGIKDISTLYINELDHGAYISDTLRIDSTTNR
CCCCCCCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHEEECCCCCCEEECEEEECCHHHH
LEALVEIYRMMRPGEPPTKDAAEALFQNLFFSEERYDLSKVGRMKFNRRLSIPDDEGSGV
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
LSKEDIVAVMKNIIHIRNGFDEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVRERL
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SLGDLNELMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLT
CCCCHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCC
RERAGFEVRDVHPTHYGRLCPIETPEGPNIGLINSLASFARTNSYGFLETPYRKVIDGVI
HHHCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
TDEVEYLSAIEEGRYVIAQANIEVDANGRMVEEQIACRHKGESTFMRASDIQYMDVSPQQ
HHHHHHHHHHHCCCEEEEEEEEEECCCCCCHHHHHHHHCCCCCCEEEECCCEEECCCHHH
IISVAASLIPFLEHDDANRALMGANMQRQAVPTLRSEKPLVGTGIERTLAVDSGVVVVAK
HHHHHHHHHHHHCCCCCCCEEECCCCHHHHCCCCCCCCCCCCCCCCCEEEECCCEEEEEE
RGGYIDYVDASRIVVKVNEDELRPGEAGIDIYNLTKYTRSNQNTCINQRPCCAVGEPVVR
CCCEEEEECCCEEEEEECCCCCCCCCCCCEEEEHHHHHCCCCCCCCCCCCCCCCCCCCCC
GDVLADGPSTDLGDLALGQNMRIAFMPWNGYNFEDSILISERVAQEDRFTTIHIQELSCI
CCEECCCCCCCCCCHHCCCCCEEEEEECCCCCCCCCEEHHHHHCCCCCEEEEEEHHHHHH
ARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVKGGDILVGKVTPKGETQLTPEE
HHHCCCCCHHHCCCCCCCCHHHHHHCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCHHH
KLLRAIFGEKASDVKDSSLRVPNSVKGTIIDVQVFTRDGVEKDKRAVEIEEMHIAQARKD
HHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LSEEFKILEEGVLSRARNLLLGAGFTETQIAAMPRKDVLVQVIDDEAKQTELEQLAEQHE
HHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHCCCHHHEEEECCCCHHHHHHHHHHHHHH
ELKADFDKKFEIKRRKITQGDDLAPGVLKIVKVYLAVKRTIQPGDKMAGRHGNKGVISKI
HHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHC
CPIEDMPYDEQGNPVDIVLNPLGVPSRMNIGQVLEVHMGAAAKGIGNKITAMLEEQRELA
CCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHH
EVRGYIKQVYELGDEVQQRVDIDSFTDDEVMRLAQNLKGGIPIATPAFDGAKEKEIKQML
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHH
ELAGLPTSGQLKLYDGRTGNEFERQVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPL
HHHCCCCCCCEEEEECCCCCHHHHHHHHHHHEEHHHHHHHCCHHHHCCCCCEEEEECCCC
GGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTQMYKNIVDGNHQMQPGM
CCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCC
PESFNVLLKEIRSLGINIELDQE
CHHHHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure
MVYSYSEKKRIRKDFGKRPQVLDIPYLLSIQLDSFKKFTDQDPTGERGLEAAFRSVFPIK
CCCCCHHHHHHHHHHCCCCCEEECCEEEEEEHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
SFSGNSELQYVSYKLGEPVFDVKECQIRGVTYSAPLRVKLRMVLYDREAAAGTVKDIKEQ
CCCCCCCEEEEEEECCCCCCCCCCEEEECEEECCCCEEEEEEEEEECCCCCCHHHHHHHH
EVYMGDIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKVLYNARIIPYR
HEEECCCEEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEEEEEC
GSWLDFEFDPKDALFVRIDRRRKLPATIILRALEYSTQEILDLFFERVEFKIKKDTLVMA
CCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHEEECCCEEEEE
LVPERLRGETASYDIKDAEGSVLVEAGRRITARHIRQLEKTNTTELEVPVEYIVGKYAAQ
ECCHHHCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHH
DYIDPDTGEVLVSANSEISLEDLAKLSLAGIKDISTLYINELDHGAYISDTLRIDSTTNR
CCCCCCCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHEEECCCCCCEEECEEEECCHHHH
LEALVEIYRMMRPGEPPTKDAAEALFQNLFFSEERYDLSKVGRMKFNRRLSIPDDEGSGV
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
LSKEDIVAVMKNIIHIRNGFDEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVRERL
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SLGDLNELMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLT
CCCCHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCC
RERAGFEVRDVHPTHYGRLCPIETPEGPNIGLINSLASFARTNSYGFLETPYRKVIDGVI
HHHCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
TDEVEYLSAIEEGRYVIAQANIEVDANGRMVEEQIACRHKGESTFMRASDIQYMDVSPQQ
HHHHHHHHHHHCCCEEEEEEEEEECCCCCCHHHHHHHHCCCCCCEEEECCCEEECCCHHH
IISVAASLIPFLEHDDANRALMGANMQRQAVPTLRSEKPLVGTGIERTLAVDSGVVVVAK
HHHHHHHHHHHHCCCCCCCEEECCCCHHHHCCCCCCCCCCCCCCCCCEEEECCCEEEEEE
RGGYIDYVDASRIVVKVNEDELRPGEAGIDIYNLTKYTRSNQNTCINQRPCCAVGEPVVR
CCCEEEEECCCEEEEEECCCCCCCCCCCCEEEEHHHHHCCCCCCCCCCCCCCCCCCCCCC
GDVLADGPSTDLGDLALGQNMRIAFMPWNGYNFEDSILISERVAQEDRFTTIHIQELSCI
CCEECCCCCCCCCCHHCCCCCEEEEEECCCCCCCCCEEHHHHHCCCCCEEEEEEHHHHHH
ARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVKGGDILVGKVTPKGETQLTPEE
HHHCCCCCHHHCCCCCCCCHHHHHHCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCHHH
KLLRAIFGEKASDVKDSSLRVPNSVKGTIIDVQVFTRDGVEKDKRAVEIEEMHIAQARKD
HHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LSEEFKILEEGVLSRARNLLLGAGFTETQIAAMPRKDVLVQVIDDEAKQTELEQLAEQHE
HHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHCCCHHHEEEECCCCHHHHHHHHHHHHHH
ELKADFDKKFEIKRRKITQGDDLAPGVLKIVKVYLAVKRTIQPGDKMAGRHGNKGVISKI
HHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHC
CPIEDMPYDEQGNPVDIVLNPLGVPSRMNIGQVLEVHMGAAAKGIGNKITAMLEEQRELA
CCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHH
EVRGYIKQVYELGDEVQQRVDIDSFTDDEVMRLAQNLKGGIPIATPAFDGAKEKEIKQML
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHH
ELAGLPTSGQLKLYDGRTGNEFERQVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPL
HHHCCCCCCCEEEEECCCCCHHHHHHHHHHHEEHHHHHHHCCHHHHCCCCCEEEEECCCC
GGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTQMYKNIVDGNHQMQPGM
CCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCC
PESFNVLLKEIRSLGINIELDQE
CHHHHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]