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The map label for this gene is murB

Identifier: 120596972

GI number: 120596972

Start: 168410

End: 169435

Strand: Direct

Name: murB

Synonym: Sputw3181_0139

Alternate gene names: 120596972

Gene position: 168410-169435 (Clockwise)

Preceding gene: 120596970

Following gene: 120596973

Centisome position: 3.58

GC content: 43.86

Gene sequence:

>1026_bases
ATGTCTTTGTCTCATAGTCTTAAGTCATTCAATACTTTTGGTCTTTCGCAGTGCTGTTCAGCCCTTGTTGAAGCTCATTC
AAAAGAAGATATTAAACATATTTGCTTGCCATTATGGCAGGACCAGCAACCATTACTTGTTTTAGGTGGCGGCAGTAATG
TCGTTTTCACCGATGATTTTCACGGCACTGTGGTGCGAGTGTTATCTAAGGGGATAAAAGTCAGCGAAGATGCTGTATAT
TTTTATCTTGAGGTTGAGGCGGGTGAAAACTGGCATGAATTAGTGGAGTTTACTTTAGCTAATGGAATGCCAGGTTTAGA
AAATCTCGCACTGATCCCTGGTACCCTCGGTGCAGCACCAATCCAAAATATTGGTGCTTATGGTGTAGAATTCTGTGACG
TTTGTGATTGGGTCGAATATCTTGATCTTGATTCCGGTGATTTTTTCCGCCTGACGGCTACTGAATGTCAGTTCTCCTAT
CGTGAGTCGATTTTTAAAGGAGCGTTGCGTGGTCGTGCGGTGATCACTGCAGTGGGATTACGCCTTGTTAAGCAGTGGCA
ACCGCATCTTGCCTATGGTCCTTTACAATCGTTTGATCCCGCATCTGTAACCGCTGCAGATATCTTTAATAAGGTATGCC
AAGTTAGACGAGAAAAGTTGCCTGATCCTAATGTATTAGGCAATGCAGGTAGTTTTTTTAAAAACCCAATAGTGAGTGCT
GCTTGCTACCTTGAGCTTGCACAACGATTTTCGACGATTGTTGGTTATGCTCAAGCCGATGGTAGTGTGAAGCTCGCGGC
TGGTTGGTTAATTGAGCAGGCAGGGTTAAAAGGTTTTATCTTAGGAAAAGCTGCCGTACACGATAAACAAGCCTTAGTTT
TAGTTAATCGTGGTGGTGCGACGGGGCAGGATATTTGCCGTTTAGCGCAACATGTTATTGAGCGCGTCAATGATACGTTT
GGTGTATTGCTAGAAGCGGAACCAAAAATTATCGGAGTCACAGGTGAAGGAGATCTGCATGTCTGA

Upstream 100 bases:

>100_bases
GCTATTTCAGTGTTTGAGCCGTAGAGGGAATACCGTTATTTGGCTGCAATTGCGGCTTTTAGTCGTTACAATAAGATATT
TCTCGCTACCGATCTATCGC

Downstream 100 bases:

>100_bases
TAACTGGGTAAGAAAGCGTGAAATTTTAACGCTATTATCTAGCGAGCATTTTGTCTCGGGCGAACAGCTTGCGAGCGAGT
TAGGCATATCTCGTGCTGCT

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSLSHSLKSFNTFGLSQCCSALVEAHSKEDIKHICLPLWQDQQPLLVLGGGSNVVFTDDFHGTVVRVLSKGIKVSEDAVY
FYLEVEAGENWHELVEFTLANGMPGLENLALIPGTLGAAPIQNIGAYGVEFCDVCDWVEYLDLDSGDFFRLTATECQFSY
RESIFKGALRGRAVITAVGLRLVKQWQPHLAYGPLQSFDPASVTAADIFNKVCQVRREKLPDPNVLGNAGSFFKNPIVSA
ACYLELAQRFSTIVGYAQADGSVKLAAGWLIEQAGLKGFILGKAAVHDKQALVLVNRGGATGQDICRLAQHVIERVNDTF
GVLLEAEPKIIGVTGEGDLHV

Sequences:

>Translated_341_residues
MSLSHSLKSFNTFGLSQCCSALVEAHSKEDIKHICLPLWQDQQPLLVLGGGSNVVFTDDFHGTVVRVLSKGIKVSEDAVY
FYLEVEAGENWHELVEFTLANGMPGLENLALIPGTLGAAPIQNIGAYGVEFCDVCDWVEYLDLDSGDFFRLTATECQFSY
RESIFKGALRGRAVITAVGLRLVKQWQPHLAYGPLQSFDPASVTAADIFNKVCQVRREKLPDPNVLGNAGSFFKNPIVSA
ACYLELAQRFSTIVGYAQADGSVKLAAGWLIEQAGLKGFILGKAAVHDKQALVLVNRGGATGQDICRLAQHVIERVNDTF
GVLLEAEPKIIGVTGEGDLHV
>Mature_340_residues
SLSHSLKSFNTFGLSQCCSALVEAHSKEDIKHICLPLWQDQQPLLVLGGGSNVVFTDDFHGTVVRVLSKGIKVSEDAVYF
YLEVEAGENWHELVEFTLANGMPGLENLALIPGTLGAAPIQNIGAYGVEFCDVCDWVEYLDLDSGDFFRLTATECQFSYR
ESIFKGALRGRAVITAVGLRLVKQWQPHLAYGPLQSFDPASVTAADIFNKVCQVRREKLPDPNVLGNAGSFFKNPIVSAA
CYLELAQRFSTIVGYAQADGSVKLAAGWLIEQAGLKGFILGKAAVHDKQALVLVNRGGATGQDICRLAQHVIERVNDTFG
VLLEAEPKIIGVTGEGDLHV

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=338, Percent_Identity=52.9585798816568, Blast_Score=354, Evalue=5e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 37000; Mature: 36868

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSHSLKSFNTFGLSQCCSALVEAHSKEDIKHICLPLWQDQQPLLVLGGGSNVVFTDDF
CCCCHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEECCCEEEEECCC
HGTVVRVLSKGIKVSEDAVYFYLEVEAGENWHELVEFTLANGMPGLENLALIPGTLGAAP
CHHHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCCCCCEEECCCCCCCCC
IQNIGAYGVEFCDVCDWVEYLDLDSGDFFRLTATECQFSYRESIFKGALRGRAVITAVGL
HHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHH
RLVKQWQPHLAYGPLQSFDPASVTAADIFNKVCQVRREKLPDPNVLGNAGSFFKNPIVSA
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ACYLELAQRFSTIVGYAQADGSVKLAAGWLIEQAGLKGFILGKAAVHDKQALVLVNRGGA
HHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHCCCCEEEEEHHHCCCCEEEEEEECCCC
TGQDICRLAQHVIERVNDTFGVLLEAEPKIIGVTGEGDLHV
CHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCC
>Mature Secondary Structure 
SLSHSLKSFNTFGLSQCCSALVEAHSKEDIKHICLPLWQDQQPLLVLGGGSNVVFTDDF
CCCHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEECCCEEEEECCC
HGTVVRVLSKGIKVSEDAVYFYLEVEAGENWHELVEFTLANGMPGLENLALIPGTLGAAP
CHHHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCCCCCEEECCCCCCCCC
IQNIGAYGVEFCDVCDWVEYLDLDSGDFFRLTATECQFSYRESIFKGALRGRAVITAVGL
HHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHH
RLVKQWQPHLAYGPLQSFDPASVTAADIFNKVCQVRREKLPDPNVLGNAGSFFKNPIVSA
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ACYLELAQRFSTIVGYAQADGSVKLAAGWLIEQAGLKGFILGKAAVHDKQALVLVNRGGA
HHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHCCCCEEEEEHHHCCCCEEEEEEECCCC
TGQDICRLAQHVIERVNDTFGVLLEAEPKIIGVTGEGDLHV
CHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA