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The map label for this gene is add [H]

Identifier: 120596871

GI number: 120596871

Start: 49575

End: 50570

Strand: Direct

Name: add [H]

Synonym: Sputw3181_0038

Alternate gene names: 120596871

Gene position: 49575-50570 (Clockwise)

Preceding gene: 120596868

Following gene: 120596877

Centisome position: 1.05

GC content: 46.59

Gene sequence:

>996_bases
ATGATTGATACATCTATTCCATTGGTGGATCTGCATCGTCACCTAGACGGTAATGTGCGGGTAAATACCATTTGGGAACT
AGGACACCAACACGGCATTGCGCTACCTGCCGATTCTTTAGAGACGCTCGCACCTTTTGTGCAAATTCAGGGGAAAGAAA
CTAGCTTAGTCGCCTTCTTAAAGAAACTCGATTGGATGGTTGCCGTACTCGCTGATTTGGATGCGGTGAAACGCGTCGCC
TATGAAAACGTTGCCGATGCGGCGTTATCTGGCTTAGATTACGCTGAGTTACGTTTTAGTCCTTACTATATGGCGATGAA
CCATAAGTTACCGATTGAAGGCGTAGTTGAGGCGGTAGTTGACGGCGTTAAAGCGGGTTTAAAAGACTATAACGTGAAGA
TCAATTTAATTGGCATTATGTCACGTTCATTTGGTCAAGCAGCTTGTACTCAAGAACTTGAAGGCTTACTTGCCCATAAA
CAACATCTCGTGGCGATGGACTTGGCAGGTGATGAATTGGGTTTCCCAGGTGAGTTATTTAACGATCACTTTAAACGTGT
TCGTGATGCTGGCCTTGCGATTACGGCTCACGCCGGTGAAGCTGCGGGCTCACAAAGTATGTGGCAAGCGATTCAAGAAC
TAGGCGCTACGCGAATTGGCCACGGGGTGAACGCGATTCACGATCCTAGGCTGATGGAATATCTCGCTAAGCACCGTATT
GGCATCGAATCTTGCCCGACCAGTAACTTGCATACTTCTACAGTGGTTTCTTACGCTGAGCATCCATTCAGAACCTTTAT
GGATGCAGGCGTGTTGATAAGCCTAAATACCGATGATCCTGGTGTGAGTGCTATCGATATTAAGCATGAGTATCGTATCG
CTAAATCTGAACTCAAGTTAACCGATGCTGAGTTAGCGCAGGTGCAACGCAACGGGGTTGAAATGGCATTTTTATCCGAT
AGTGAGCGCAAAGCACTCTATGCCGCTAAGGTATAA

Upstream 100 bases:

>100_bases
TCTGGTCCATAAATGCCCCTGAAAATGCGTGTTAAACTTAGTGTCCGCCCGCGACCAAATAACAAAAGCATTGGCTGGGT
AGTTCAAATAGGGGTTAAAT

Downstream 100 bases:

>100_bases
GTCGATTCTGAGTCGTTAATAAAAATTGCCATCAATAAAAAATCCGACTTAGAGTCGGATTTTTTGTGCAGCACTTGTGA
GTACGGCAAAGAGCCTTTAG

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MIDTSIPLVDLHRHLDGNVRVNTIWELGHQHGIALPADSLETLAPFVQIQGKETSLVAFLKKLDWMVAVLADLDAVKRVA
YENVADAALSGLDYAELRFSPYYMAMNHKLPIEGVVEAVVDGVKAGLKDYNVKINLIGIMSRSFGQAACTQELEGLLAHK
QHLVAMDLAGDELGFPGELFNDHFKRVRDAGLAITAHAGEAAGSQSMWQAIQELGATRIGHGVNAIHDPRLMEYLAKHRI
GIESCPTSNLHTSTVVSYAEHPFRTFMDAGVLISLNTDDPGVSAIDIKHEYRIAKSELKLTDAELAQVQRNGVEMAFLSD
SERKALYAAKV

Sequences:

>Translated_331_residues
MIDTSIPLVDLHRHLDGNVRVNTIWELGHQHGIALPADSLETLAPFVQIQGKETSLVAFLKKLDWMVAVLADLDAVKRVA
YENVADAALSGLDYAELRFSPYYMAMNHKLPIEGVVEAVVDGVKAGLKDYNVKINLIGIMSRSFGQAACTQELEGLLAHK
QHLVAMDLAGDELGFPGELFNDHFKRVRDAGLAITAHAGEAAGSQSMWQAIQELGATRIGHGVNAIHDPRLMEYLAKHRI
GIESCPTSNLHTSTVVSYAEHPFRTFMDAGVLISLNTDDPGVSAIDIKHEYRIAKSELKLTDAELAQVQRNGVEMAFLSD
SERKALYAAKV
>Mature_331_residues
MIDTSIPLVDLHRHLDGNVRVNTIWELGHQHGIALPADSLETLAPFVQIQGKETSLVAFLKKLDWMVAVLADLDAVKRVA
YENVADAALSGLDYAELRFSPYYMAMNHKLPIEGVVEAVVDGVKAGLKDYNVKINLIGIMSRSFGQAACTQELEGLLAHK
QHLVAMDLAGDELGFPGELFNDHFKRVRDAGLAITAHAGEAAGSQSMWQAIQELGATRIGHGVNAIHDPRLMEYLAKHRI
GIESCPTSNLHTSTVVSYAEHPFRTFMDAGVLISLNTDDPGVSAIDIKHEYRIAKSELKLTDAELAQVQRNGVEMAFLSD
SERKALYAAKV

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=338, Percent_Identity=32.5443786982249, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI226693318, Length=334, Percent_Identity=23.0538922155689, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1787910, Length=326, Percent_Identity=61.9631901840491, Blast_Score=426, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI32565969, Length=334, Percent_Identity=29.6407185628743, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17538512, Length=334, Percent_Identity=29.6407185628743, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI115537133, Length=325, Percent_Identity=25.2307692307692, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324188, Length=326, Percent_Identity=24.2331288343558, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24645260, Length=327, Percent_Identity=24.7706422018349, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 36218; Mature: 36218

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00485 A_DEAMINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDTSIPLVDLHRHLDGNVRVNTIWELGHQHGIALPADSLETLAPFVQIQGKETSLVAFL
CCCCCCCHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCHHHHHHHHHHEECCCCHHHHHHH
KKLDWMVAVLADLDAVKRVAYENVADAALSGLDYAELRFSPYYMAMNHKLPIEGVVEAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCCCHHHHHHHHH
DGVKAGLKDYNVKINLIGIMSRSFGQAACTQELEGLLAHKQHLVAMDLAGDELGFPGELF
HHHHHCCHHCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHH
NDHFKRVRDAGLAITAHAGEAAGSQSMWQAIQELGATRIGHGVNAIHDPRLMEYLAKHRI
HHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHCC
GIESCPTSNLHTSTVVSYAEHPFRTFMDAGVLISLNTDDPGVSAIDIKHEYRIAKSELKL
CCCCCCCCCCCHHHHHHHHHCHHHHHHCCCEEEEECCCCCCCEEEEEHHHHHHHHHHHHC
TDAELAQVQRNGVEMAFLSDSERKALYAAKV
CHHHHHHHHHCCCEEEEECCCCCCEEEEECC
>Mature Secondary Structure
MIDTSIPLVDLHRHLDGNVRVNTIWELGHQHGIALPADSLETLAPFVQIQGKETSLVAFL
CCCCCCCHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCHHHHHHHHHHEECCCCHHHHHHH
KKLDWMVAVLADLDAVKRVAYENVADAALSGLDYAELRFSPYYMAMNHKLPIEGVVEAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCCCHHHHHHHHH
DGVKAGLKDYNVKINLIGIMSRSFGQAACTQELEGLLAHKQHLVAMDLAGDELGFPGELF
HHHHHCCHHCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHH
NDHFKRVRDAGLAITAHAGEAAGSQSMWQAIQELGATRIGHGVNAIHDPRLMEYLAKHRI
HHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHCC
GIESCPTSNLHTSTVVSYAEHPFRTFMDAGVLISLNTDDPGVSAIDIKHEYRIAKSELKL
CCCCCCCCCCCHHHHHHHHHCHHHHHHCCCEEEEECCCCCCCEEEEEHHHHHHHHHHHHC
TDAELAQVQRNGVEMAFLSDSERKALYAAKV
CHHHHHHHHHCCCEEEEECCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA