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The map label for this gene is nudK [H]

Identifier: 119947278

GI number: 119947278

Start: 4493040

End: 4493612

Strand: Direct

Name: nudK [H]

Synonym: Ping_3682

Alternate gene names: 119947278

Gene position: 4493040-4493612 (Clockwise)

Preceding gene: 119947277

Following gene: 119947296

Centisome position: 98.54

GC content: 41.01

Gene sequence:

>573_bases
ATGGCCAATACGCTCAAAAATTTTAAACTTCAGCCTTTAGTTGATGCGAAATTTATTAAAACTTCACTGGCAACCTATGA
GCAAAACGGTGTCAAAAAATCATGGGAAGTAGTCAAAGCGCATGACTCTGTAGCTATCCTTATTTATCATAAAGAAAAAG
AGGCTTTTGTGCTTGTAGAACAGTTCCGCCCGGCAGTGTATTTGAACAATGATAATGGATTAACCATTGAGCTGTGCGCG
GGTATTGTCGATAAAGACCTCTCTTTAAAACAGATAGCCAAAGAAGAAATAGAAGAAGAGTGCGGCTATGATATAGCGCT
TGAGAGGATAGAAGAAATCACCTCTTTTCATACCTCCGTAGGCTTTGCCGGAAGCAGGCAAATACTCTACTATGCAGAAG
TTGATCAGAGTATGAAGGTCAATGAAGGCGGCGGTATCGATGCTGAAATGATCGAAGTTGTGTACCTGCCGATAAACGAA
GCCAAAGCGCTTATTTTTGATGTCAGCATCGCAAAAACATCCGGGCTTATGTTTGCATTTATGTGGTGGTTTGAACAGCA
CAAGAATGGCTAA

Upstream 100 bases:

>100_bases
AGTGCGGCAATTATCATAAAGCAATAAAGACTGGCAACAACACAACACAGTATTAGCTTTTTTTGGAATGCTAATACACC
GACAAGTATAAGGAGTTAAG

Downstream 100 bases:

>100_bases
AATACCATTGATTTTATTTAAGTAAACCGTGATAGGCCGTTGCGCCTATCACGTAAAATAGCCCTATCTTTTGTCCGTTG
ATCTTCAATGTCGGTATAAA

Product: UDP-sugar diphosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MANTLKNFKLQPLVDAKFIKTSLATYEQNGVKKSWEVVKAHDSVAILIYHKEKEAFVLVEQFRPAVYLNNDNGLTIELCA
GIVDKDLSLKQIAKEEIEEECGYDIALERIEEITSFHTSVGFAGSRQILYYAEVDQSMKVNEGGGIDAEMIEVVYLPINE
AKALIFDVSIAKTSGLMFAFMWWFEQHKNG

Sequences:

>Translated_190_residues
MANTLKNFKLQPLVDAKFIKTSLATYEQNGVKKSWEVVKAHDSVAILIYHKEKEAFVLVEQFRPAVYLNNDNGLTIELCA
GIVDKDLSLKQIAKEEIEEECGYDIALERIEEITSFHTSVGFAGSRQILYYAEVDQSMKVNEGGGIDAEMIEVVYLPINE
AKALIFDVSIAKTSGLMFAFMWWFEQHKNG
>Mature_189_residues
ANTLKNFKLQPLVDAKFIKTSLATYEQNGVKKSWEVVKAHDSVAILIYHKEKEAFVLVEQFRPAVYLNNDNGLTIELCAG
IVDKDLSLKQIAKEEIEEECGYDIALERIEEITSFHTSVGFAGSRQILYYAEVDQSMKVNEGGGIDAEMIEVVYLPINEA
KALIFDVSIAKTSGLMFAFMWWFEQHKNG

Specific function: Catalyzes the hydrolysis of GDP-mannose [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI37594467, Length=200, Percent_Identity=36.5, Blast_Score=149, Evalue=2e-36,
Organism=Escherichia coli, GI1788810, Length=136, Percent_Identity=33.8235294117647, Blast_Score=74, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17558808, Length=199, Percent_Identity=36.1809045226131, Blast_Score=129, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24650557, Length=201, Percent_Identity=41.7910447761194, Blast_Score=163, Evalue=8e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004385
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 21477; Mature: 21346

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTLKNFKLQPLVDAKFIKTSLATYEQNGVKKSWEVVKAHDSVAILIYHKEKEAFVLVE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHEEEECCCEEEEEEECCCCEEEEEE
QFRPAVYLNNDNGLTIELCAGIVDKDLSLKQIAKEEIEEECGYDIALERIEEITSFHTSV
CCCCEEEEECCCCEEEEEECCHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
GFAGSRQILYYAEVDQSMKVNEGGGIDAEMIEVVYLPINEAKALIFDVSIAKTSGLMFAF
CCCCCCEEEEEEECCCCEEECCCCCCCCEEEEEEEEECCCCEEEEEEEEEHHHCCHHHHH
MWWFEQHKNG
HHHHHHHCCC
>Mature Secondary Structure 
ANTLKNFKLQPLVDAKFIKTSLATYEQNGVKKSWEVVKAHDSVAILIYHKEKEAFVLVE
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHEEEECCCEEEEEEECCCCEEEEEE
QFRPAVYLNNDNGLTIELCAGIVDKDLSLKQIAKEEIEEECGYDIALERIEEITSFHTSV
CCCCEEEEECCCCEEEEEECCHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
GFAGSRQILYYAEVDQSMKVNEGGGIDAEMIEVVYLPINEAKALIFDVSIAKTSGLMFAF
CCCCCCEEEEEEECCCCEEECCCCCCCCEEEEEEEEECCCCEEEEEEEEEHHHCCHHHHH
MWWFEQHKNG
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA