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The map label for this gene is siaT [H]

Identifier: 119947273

GI number: 119947273

Start: 4484915

End: 4486231

Strand: Reverse

Name: siaT [H]

Synonym: Ping_3673

Alternate gene names: 119947273

Gene position: 4486231-4484915 (Counterclockwise)

Preceding gene: 119947274

Following gene: 119947272

Centisome position: 98.39

GC content: 40.55

Gene sequence:

>1317_bases
ATGGATCCTCTAATTCTTAGTGCCTTGGTCGGTATAACGACCATTCTTATATTGTTTTCTGGTGTATCTGTTGGTATTGG
TTTGCTCGTAGTTTCAGGATTATTTTTGATTGTTTTTGATGGATTACAGTCGTTACAGCTAATGCCAGAAATATTTTTTG
GCAAATTGGATAGCTTTGCTCTTTTATCAATCCCTATGTTTATTCTCATGGGATCGACTATATCCTCTACAAAAGCAGGC
GCTGATTTGTATGAAGCGCTAGAGCGATGGTTAACAAGAGTTCCCGGTGGTTTAGTGGTATCAAATTTGGGGGCTTGTGC
TCTGTTTGCTGCTATGTCCGGTTCTAGCCCTGCCACTTGTGCAGCGATTGGGAAAATGGGTATTCCTGAAATGCTTAAGC
GAGGTTATCCTGAAGGAATTGCAACCGGATCAATTGCTGCCGGTGGTACATTAGGAATTTTAATTCCTCCATCAGTCACC
ATGATTGTTTATGGCATTGCAACAGAGACATCAATTGGTCGTTTATTTCTTGCAGGAGTGCTGCCTGGCCTGATGCTTGT
GGGATTGTTCATGGCTTGGTCTATATACGCAACTTGGCGTTCAGGTAACCGTGCGTTAATGACACCAATCAATTATAGCT
GGCGAGAAAAATTCGAAATACTGCCTCGTGTATTACCATTTGTTGGCATTATTATTGCTGTGCTTTATACCATGTATGGC
GGTATTGCAACGCCATCTGAAACAGCAGCTCTGGGCGCAATAATGTGCTTAGTTGTTGCGATGATTATTTATCGTTTAAC
TAGTCCGAAAGATTTGTGGACAATATTGCGCGATAGCACCAGAGAGAGCGTAATGATTTTATTTATCATTGCAGCAGCGG
GCGTTTTTTCTTATATGTTGTCTAGCCTTTATATTACTCAAGCAATAGCTGAGTGGATTGGAGCACTAGAAATTAATCGT
TGGAGTTTAATGATTTTAATTAATTTCTTTTTGATTATAGCGGGATTCTTCCTCCCTCCGGTAGCAGTAATTTTAATGAC
AGCCCCTATTTTGTTGCCTGTGCTTATGAATGCTGGCTTTGACCCTATCTGGTTTGCTGTAGTCCTTACCATCAATATGG
AAATTGGTTTAATTTCACCACCAGTCGGTTTAAATCTTTATGTGATTAATGGCATTACTCCAAACATTTCTTTGAAAACT
ATTCTGTGGGGTTCATTACCTTTTGTTGCCTGCATGATTATTGCCATTGTTTTACTCTGCTTGTTCCCTAGCATTGCTAC
ATGGCTACCTGAGGCCGTAATGGGCTCAGCTATATAA

Upstream 100 bases:

>100_bases
CGATGATCATTGGTTTTGGTTTACTTTTTTTACAATTAGTTGCCGATTTAGTTGCTGTTTTATTAAAAATTGATAAACCT
TTTGGGTTGGGAGAAAACTA

Downstream 100 bases:

>100_bases
TATAATTTAATTATTAAGGAGTATTAGCTATGAAGATCAAATCTAGAAATTATCGTGTTGGGCTAATTGTGCCTAGTTCA
AATATTACAATGGAAACCGA

Product: TRAP dicarboxylate transporter, DctM subunit

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MDPLILSALVGITTILILFSGVSVGIGLLVVSGLFLIVFDGLQSLQLMPEIFFGKLDSFALLSIPMFILMGSTISSTKAG
ADLYEALERWLTRVPGGLVVSNLGACALFAAMSGSSPATCAAIGKMGIPEMLKRGYPEGIATGSIAAGGTLGILIPPSVT
MIVYGIATETSIGRLFLAGVLPGLMLVGLFMAWSIYATWRSGNRALMTPINYSWREKFEILPRVLPFVGIIIAVLYTMYG
GIATPSETAALGAIMCLVVAMIIYRLTSPKDLWTILRDSTRESVMILFIIAAAGVFSYMLSSLYITQAIAEWIGALEINR
WSLMILINFFLIIAGFFLPPVAVILMTAPILLPVLMNAGFDPIWFAVVLTINMEIGLISPPVGLNLYVINGITPNISLKT
ILWGSLPFVACMIIAIVLLCLFPSIATWLPEAVMGSAI

Sequences:

>Translated_438_residues
MDPLILSALVGITTILILFSGVSVGIGLLVVSGLFLIVFDGLQSLQLMPEIFFGKLDSFALLSIPMFILMGSTISSTKAG
ADLYEALERWLTRVPGGLVVSNLGACALFAAMSGSSPATCAAIGKMGIPEMLKRGYPEGIATGSIAAGGTLGILIPPSVT
MIVYGIATETSIGRLFLAGVLPGLMLVGLFMAWSIYATWRSGNRALMTPINYSWREKFEILPRVLPFVGIIIAVLYTMYG
GIATPSETAALGAIMCLVVAMIIYRLTSPKDLWTILRDSTRESVMILFIIAAAGVFSYMLSSLYITQAIAEWIGALEINR
WSLMILINFFLIIAGFFLPPVAVILMTAPILLPVLMNAGFDPIWFAVVLTINMEIGLISPPVGLNLYVINGITPNISLKT
ILWGSLPFVACMIIAIVLLCLFPSIATWLPEAVMGSAI
>Mature_438_residues
MDPLILSALVGITTILILFSGVSVGIGLLVVSGLFLIVFDGLQSLQLMPEIFFGKLDSFALLSIPMFILMGSTISSTKAG
ADLYEALERWLTRVPGGLVVSNLGACALFAAMSGSSPATCAAIGKMGIPEMLKRGYPEGIATGSIAAGGTLGILIPPSVT
MIVYGIATETSIGRLFLAGVLPGLMLVGLFMAWSIYATWRSGNRALMTPINYSWREKFEILPRVLPFVGIIIAVLYTMYG
GIATPSETAALGAIMCLVVAMIIYRLTSPKDLWTILRDSTRESVMILFIIAAAGVFSYMLSSLYITQAIAEWIGALEINR
WSLMILINFFLIIAGFFLPPVAVILMTAPILLPVLMNAGFDPIWFAVVLTINMEIGLISPPVGLNLYVINGITPNISLKT
ILWGSLPFVACMIIAIVLLCLFPSIATWLPEAVMGSAI

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=380, Percent_Identity=29.4736842105263, Blast_Score=142, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 46859; Mature: 46859

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPLILSALVGITTILILFSGVSVGIGLLVVSGLFLIVFDGLQSLQLMPEIFFGKLDSFA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LLSIPMFILMGSTISSTKAGADLYEALERWLTRVPGGLVVSNLGACALFAAMSGSSPATC
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHH
AAIGKMGIPEMLKRGYPEGIATGSIAAGGTLGILIPPSVTMIVYGIATETSIGRLFLAGV
HHHHCCCCHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEHHCCCHHHHHHHHHH
LPGLMLVGLFMAWSIYATWRSGNRALMTPINYSWREKFEILPRVLPFVGIIIAVLYTMYG
HHHHHHHHHHHHHHHHHHEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GIATPSETAALGAIMCLVVAMIIYRLTSPKDLWTILRDSTRESVMILFIIAAAGVFSYML
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
SSLYITQAIAEWIGALEINRWSLMILINFFLIIAGFFLPPVAVILMTAPILLPVLMNAGF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DPIWFAVVLTINMEIGLISPPVGLNLYVINGITPNISLKTILWGSLPFVACMIIAIVLLC
CHHHHHHHHHHCCEEEEECCCCCCEEEEEECCCCCCEEHHHHHCCHHHHHHHHHHHHHHH
LFPSIATWLPEAVMGSAI
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDPLILSALVGITTILILFSGVSVGIGLLVVSGLFLIVFDGLQSLQLMPEIFFGKLDSFA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LLSIPMFILMGSTISSTKAGADLYEALERWLTRVPGGLVVSNLGACALFAAMSGSSPATC
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHH
AAIGKMGIPEMLKRGYPEGIATGSIAAGGTLGILIPPSVTMIVYGIATETSIGRLFLAGV
HHHHCCCCHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEHHCCCHHHHHHHHHH
LPGLMLVGLFMAWSIYATWRSGNRALMTPINYSWREKFEILPRVLPFVGIIIAVLYTMYG
HHHHHHHHHHHHHHHHHHEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GIATPSETAALGAIMCLVVAMIIYRLTSPKDLWTILRDSTRESVMILFIIAAAGVFSYML
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
SSLYITQAIAEWIGALEINRWSLMILINFFLIIAGFFLPPVAVILMTAPILLPVLMNAGF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DPIWFAVVLTINMEIGLISPPVGLNLYVINGITPNISLKTILWGSLPFVACMIIAIVLLC
CHHHHHHHHHHCCEEEEECCCCCCEEEEEECCCCCCEEHHHHHCCHHHHHHHHHHHHHHH
LFPSIATWLPEAVMGSAI
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]