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The map label for this gene is oxaA

Identifier: 119947213

GI number: 119947213

Start: 4424835

End: 4426535

Strand: Direct

Name: oxaA

Synonym: Ping_3611

Alternate gene names: 119947213

Gene position: 4424835-4426535 (Clockwise)

Preceding gene: 119947212

Following gene: 119947214

Centisome position: 97.04

GC content: 42.21

Gene sequence:

>1701_bases
ATGGAATCCCAACGCAATTTACTTTTACTCGCCCTGCTGTTTGTGAGCTTTTTGCTTTATACCGCATGGGTCGAAGAAAA
AACTCCTCAAGTAGCTCCACAAGTGCAAACAGAACAAGTTGATTCATCTGTTCCGGCTTCAGTTGCTTCCAGTGCCAACA
GTGCCAATTTAAGTGATGGCGTGCCAAACTCACCCCAGCAAAGCAGTACCGATGCCACTTCAACTGAGCTGCCAGCAAGT
CAATCTGTTACGATAGCCAATGACGAATTACGCTTAACCATCTCGCTAGTCGGTGGTGATATTATTAAAGCGGATCTATT
ACAACATGATGCCACACTTGATTCTGACACTCCTTACCGTCTATTGGATAGCGGTAATGGATTTACCTATATCGCACAAA
GTGGTTTGATTGGGCAAGGCCCCGATGCTAATAAAAATGGTCGCCCTCTATACGATACAACTGATACAGAATCGGTCTTA
GCCGATGGCCAGGCTGAAGTATCAACAATGCTGCATTTTGTTGATGCAGATGGTAATATTTTCATTAAAACCTTCACCCT
TAAACGTGGTGAATATGTAACTAATGTTGCTTACCAAATTGAAAACAAAACAGATAGTCCGCTCAATGTTCAGCTCTATG
CACAGTTAAGAGAAACATTATCCGACGATAGCGGCAGTATGGTGATGCCTGTTTATCGCGGTGGCGCTTTCTCAACGACA
GAGACCCGTTACGAAAAATACAGCTTTAGTGATATGCAAGACGGGCCATTGCAAAAAACAACTGAAGGCGGTTGGGTGGC
AATGTTACAACATTATTTTGTATCAGCATGGATCCCATCCCCTACGGATCAAAATGTACTGTACAGTAATATTATTCAAG
ATAAAGAGGCCGCAATAGGTTTTAAAGCACCATCGAAAACCATTGCACCACAAAGTGTTGCTGAGCTCGAGACTAATTTG
TGGGTCGGTCCTAAAATACAGGAAGAGATGGCCCTTGTTGCTAAGAACCTTGATTTAACCGTTGATTACGGCTGGTTATG
GTTTATTGCTCAACCACTGTTCAAACTGCTGTTATTCTTCCAGGGCATTGTTGGTAACTGGGGTGTTGCGATTATTCTGA
TTACCTTTACCGTCAAAGGTGCACTTTACCCTCTGACTAAAGCGCAATACACTTCTATGGCTAAAATGCGCCTATTGCAG
CCTAAGATTAAAGAATTACGCGAACAGTTTGGAGAAGACCGTCAGAAAGTATCCAAAGCAATGATGGAACTGTATAAGAA
AGAGAAAGTAAACCCGCTCGGTGGTTGTTTCCCTATCCTATTACAAATGCCTATTTTCATTGCTTTATACTGGTCGTTGA
TGGAATCGGTTGAATTGCGTCATGCACCCTTTATGTTATGGATTCAGGATCTGTCGGTACAAGACCCTTATTACATTCTG
CCGATCCTGATGGGTGTGAGCATGTTCTTTATCCAGAAAATGTCTCCAACAACAGTACAAGATCCAATGCAGCAGAAAGT
AATGCAGTTTATGCCGGTTATTTTCACTTTCTTCTTCCTCTGGTTCCCTGCAGGTCTGGTACTTTACTGGTTAATGAGTA
ATGTTGTCACACTGATCCAACAAACGCTGATTTATCGCAGCTTTGAAAAAAAGGGTTTGCATCAAAAGGAAAAAGAACCT
GTGGTGCTTACTAAAAAATAA

Upstream 100 bases:

>100_bases
ATTATAAAATGCCAGCCTTTCAGTGAGGGTGGTTACGATCCTGTGCCTACTTGTTGTGCTAATAAAAATAAACCTAACTA
AATAGAGAATAAAAAACGTT

Downstream 100 bases:

>100_bases
TTTATTTTCCCGATAACCATTGATAAAAAGGCGACTATAAAAAGTCGCCTTTTTTGTATAATAACTTTTTATATAATAAT
TGAAATTTTGAGGTCTAATC

Product: 60 kDa inner membrane insertion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MESQRNLLLLALLFVSFLLYTAWVEEKTPQVAPQVQTEQVDSSVPASVASSANSANLSDGVPNSPQQSSTDATSTELPAS
QSVTIANDELRLTISLVGGDIIKADLLQHDATLDSDTPYRLLDSGNGFTYIAQSGLIGQGPDANKNGRPLYDTTDTESVL
ADGQAEVSTMLHFVDADGNIFIKTFTLKRGEYVTNVAYQIENKTDSPLNVQLYAQLRETLSDDSGSMVMPVYRGGAFSTT
ETRYEKYSFSDMQDGPLQKTTEGGWVAMLQHYFVSAWIPSPTDQNVLYSNIIQDKEAAIGFKAPSKTIAPQSVAELETNL
WVGPKIQEEMALVAKNLDLTVDYGWLWFIAQPLFKLLLFFQGIVGNWGVAIILITFTVKGALYPLTKAQYTSMAKMRLLQ
PKIKELREQFGEDRQKVSKAMMELYKKEKVNPLGGCFPILLQMPIFIALYWSLMESVELRHAPFMLWIQDLSVQDPYYIL
PILMGVSMFFIQKMSPTTVQDPMQQKVMQFMPVIFTFFFLWFPAGLVLYWLMSNVVTLIQQTLIYRSFEKKGLHQKEKEP
VVLTKK

Sequences:

>Translated_566_residues
MESQRNLLLLALLFVSFLLYTAWVEEKTPQVAPQVQTEQVDSSVPASVASSANSANLSDGVPNSPQQSSTDATSTELPAS
QSVTIANDELRLTISLVGGDIIKADLLQHDATLDSDTPYRLLDSGNGFTYIAQSGLIGQGPDANKNGRPLYDTTDTESVL
ADGQAEVSTMLHFVDADGNIFIKTFTLKRGEYVTNVAYQIENKTDSPLNVQLYAQLRETLSDDSGSMVMPVYRGGAFSTT
ETRYEKYSFSDMQDGPLQKTTEGGWVAMLQHYFVSAWIPSPTDQNVLYSNIIQDKEAAIGFKAPSKTIAPQSVAELETNL
WVGPKIQEEMALVAKNLDLTVDYGWLWFIAQPLFKLLLFFQGIVGNWGVAIILITFTVKGALYPLTKAQYTSMAKMRLLQ
PKIKELREQFGEDRQKVSKAMMELYKKEKVNPLGGCFPILLQMPIFIALYWSLMESVELRHAPFMLWIQDLSVQDPYYIL
PILMGVSMFFIQKMSPTTVQDPMQQKVMQFMPVIFTFFFLWFPAGLVLYWLMSNVVTLIQQTLIYRSFEKKGLHQKEKEP
VVLTKK
>Mature_566_residues
MESQRNLLLLALLFVSFLLYTAWVEEKTPQVAPQVQTEQVDSSVPASVASSANSANLSDGVPNSPQQSSTDATSTELPAS
QSVTIANDELRLTISLVGGDIIKADLLQHDATLDSDTPYRLLDSGNGFTYIAQSGLIGQGPDANKNGRPLYDTTDTESVL
ADGQAEVSTMLHFVDADGNIFIKTFTLKRGEYVTNVAYQIENKTDSPLNVQLYAQLRETLSDDSGSMVMPVYRGGAFSTT
ETRYEKYSFSDMQDGPLQKTTEGGWVAMLQHYFVSAWIPSPTDQNVLYSNIIQDKEAAIGFKAPSKTIAPQSVAELETNL
WVGPKIQEEMALVAKNLDLTVDYGWLWFIAQPLFKLLLFFQGIVGNWGVAIILITFTVKGALYPLTKAQYTSMAKMRLLQ
PKIKELREQFGEDRQKVSKAMMELYKKEKVNPLGGCFPILLQMPIFIALYWSLMESVELRHAPFMLWIQDLSVQDPYYIL
PILMGVSMFFIQKMSPTTVQDPMQQKVMQFMPVIFTFFFLWFPAGLVLYWLMSNVVTLIQQTLIYRSFEKKGLHQKEKEP
VVLTKK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Homo sapiens, GI223718097, Length=194, Percent_Identity=27.8350515463918, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1790140, Length=568, Percent_Identity=52.8169014084507, Blast_Score=592, Evalue=1e-170,
Organism=Drosophila melanogaster, GI24662345, Length=195, Percent_Identity=25.1282051282051, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356443, Length=195, Percent_Identity=25.1282051282051, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_PSYIN (A1T0M9)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_944893.1
- ProteinModelPortal:   A1T0M9
- SMR:   A1T0M9
- STRING:   A1T0M9
- GeneID:   4625125
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_3611
- eggNOG:   COG0706
- HOGENOM:   HBG507812
- OMA:   TYRGAAF
- PhylomeDB:   A1T0M9
- BioCyc:   PING357804:PING_3611-MONOMER
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 63546; Mature: 63546

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1abd0b10)-; HASH(0x1b9dc0dc)-; HASH(0x1b9dea70)-; HASH(0x1a5c52d8)-; HASH(0x1b9dc0b8)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESQRNLLLLALLFVSFLLYTAWVEEKTPQVAPQVQTEQVDSSVPASVASSANSANLSDG
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCHHHHCCCCCCCCCCC
VPNSPQQSSTDATSTELPASQSVTIANDELRLTISLVGGDIIKADLLQHDATLDSDTPYR
CCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEEEECCCHHHHHHHHHCCCCCCCCCEE
LLDSGNGFTYIAQSGLIGQGPDANKNGRPLYDTTDTESVLADGQAEVSTMLHFVDADGNI
EEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHEEECCCCE
FIKTFTLKRGEYVTNVAYQIENKTDSPLNVQLYAQLRETLSDDSGSMVMPVYRGGAFSTT
EEEEEEEECCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
ETRYEKYSFSDMQDGPLQKTTEGGWVAMLQHYFVSAWIPSPTDQNVLYSNIIQDKEAAIG
HHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCC
FKAPSKTIAPQSVAELETNLWVGPKIQEEMALVAKNLDLTVDYGWLWFIAQPLFKLLLFF
CCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHH
QGIVGNWGVAIILITFTVKGALYPLTKAQYTSMAKMRLLQPKIKELREQFGEDRQKVSKA
HHHHCCCCCEEEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
MMELYKKEKVNPLGGCFPILLQMPIFIALYWSLMESVELRHAPFMLWIQDLSVQDPYYIL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHH
PILMGVSMFFIQKMSPTTVQDPMQQKVMQFMPVIFTFFFLWFPAGLVLYWLMSNVVTLIQ
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTLIYRSFEKKGLHQKEKEPVVLTKK
HHHHHHHHHHCCCCCCCCCCEEEECH
>Mature Secondary Structure
MESQRNLLLLALLFVSFLLYTAWVEEKTPQVAPQVQTEQVDSSVPASVASSANSANLSDG
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCHHHHCCCCCCCCCCC
VPNSPQQSSTDATSTELPASQSVTIANDELRLTISLVGGDIIKADLLQHDATLDSDTPYR
CCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEEEECCCHHHHHHHHHCCCCCCCCCEE
LLDSGNGFTYIAQSGLIGQGPDANKNGRPLYDTTDTESVLADGQAEVSTMLHFVDADGNI
EEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHEEECCCCE
FIKTFTLKRGEYVTNVAYQIENKTDSPLNVQLYAQLRETLSDDSGSMVMPVYRGGAFSTT
EEEEEEEECCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
ETRYEKYSFSDMQDGPLQKTTEGGWVAMLQHYFVSAWIPSPTDQNVLYSNIIQDKEAAIG
HHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCC
FKAPSKTIAPQSVAELETNLWVGPKIQEEMALVAKNLDLTVDYGWLWFIAQPLFKLLLFF
CCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHH
QGIVGNWGVAIILITFTVKGALYPLTKAQYTSMAKMRLLQPKIKELREQFGEDRQKVSKA
HHHHCCCCCEEEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
MMELYKKEKVNPLGGCFPILLQMPIFIALYWSLMESVELRHAPFMLWIQDLSVQDPYYIL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHH
PILMGVSMFFIQKMSPTTVQDPMQQKVMQFMPVIFTFFFLWFPAGLVLYWLMSNVVTLIQ
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTLIYRSFEKKGLHQKEKEPVVLTKK
HHHHHHHHHHCCCCCCCCCCEEEECH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA