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The map label for this gene is yeiG [H]

Identifier: 119947133

GI number: 119947133

Start: 4349596

End: 4350447

Strand: Direct

Name: yeiG [H]

Synonym: Ping_3531

Alternate gene names: 119947133

Gene position: 4349596-4350447 (Clockwise)

Preceding gene: 119947132

Following gene: 119947141

Centisome position: 95.39

GC content: 41.67

Gene sequence:

>852_bases
ATGAGCATAGAAAATATTAGCACCAATAAAGTATTTGATGGCTGGCATAAACAATATAACCATCAATCACAGACACTTAA
TTGTAAAATGCGTTTTGCGATTTATTTACCACCGCAAGCCGCTAATGGAAAAAAAGTACCCGTTATGTACTGGTTATCCG
GCTTAACCTGCACCGATGAAAATTTTATGCAAAAAGCAAGCGCACTTAAGTTGGCTGCCGAATTGGGGATCGCTATTGTA
GCCCCCGATACCAGTCCGCGCGGAGAAGGTGTCGCAGATGATCCAGAACAAGCTTATGATCTTGGTTTAGGGGCGGGCTT
TTATGTTAATGCCACGCAGGCGCCATGGAATAAACATTATCAGATGTATGATTATGTGGTCAATGAGTTACCGGGGATCA
TCGAAAATCATTTTCCGGTCAATAAACAGCGGGTTATTAGCGGTCATTCAATGGGCGGACATGGCGCATTAATGATTGCA
CTGCGTAATCCTAGTCTCTATCAATCGGCGACTGCCTTTAGTCCCGTTAGTAACCCAGTCAATTGCCCTTGGGGGAAAAA
AGCATTTAGCGCGTATCTTGGTGCCGATTCAAAAAAATGGTTACAATACGATACCTGTGAATTAATCGCTTTAGCGCAAC
AAAAAATCCCGATGTTAGTTGATCAGGGTGAGAATGATAATTTTTTAGAAGAGCAGCTAAAACCCCATAGTTTAGTGGTA
GCCGCCAGCAGCAATCATTATCCATTGAGTTTAAATATGCGCCAGGGTTACGACCATAGTTATTATTTTATTGCCAGTTT
CATTGAGACACATCTTTATTTTCACGCGGCTAATTTAGGCTTAACTGAATAA

Upstream 100 bases:

>100_bases
CTCATTTCGGAATAAGCAACACAACTGAGGTTAAATAACCATCCTGATATTAATCGTTTCTAAATTTTTAGAAACGGTTT
TTTAACAATCTGGGAAAATC

Downstream 100 bases:

>100_bases
AATCATGTTAACGGCAAACAGCTTATACCAAAAGAATTAATGAAGTGATCAATGATTGCGAAGGAAAAATAAGCACTAAT
AAGGCGTGAGTTGCATTCGA

Product: carboxylesterase

Products: NA

Alternate protein names: FGH [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MSIENISTNKVFDGWHKQYNHQSQTLNCKMRFAIYLPPQAANGKKVPVMYWLSGLTCTDENFMQKASALKLAAELGIAIV
APDTSPRGEGVADDPEQAYDLGLGAGFYVNATQAPWNKHYQMYDYVVNELPGIIENHFPVNKQRVISGHSMGGHGALMIA
LRNPSLYQSATAFSPVSNPVNCPWGKKAFSAYLGADSKKWLQYDTCELIALAQQKIPMLVDQGENDNFLEEQLKPHSLVV
AASSNHYPLSLNMRQGYDHSYYFIASFIETHLYFHAANLGLTE

Sequences:

>Translated_283_residues
MSIENISTNKVFDGWHKQYNHQSQTLNCKMRFAIYLPPQAANGKKVPVMYWLSGLTCTDENFMQKASALKLAAELGIAIV
APDTSPRGEGVADDPEQAYDLGLGAGFYVNATQAPWNKHYQMYDYVVNELPGIIENHFPVNKQRVISGHSMGGHGALMIA
LRNPSLYQSATAFSPVSNPVNCPWGKKAFSAYLGADSKKWLQYDTCELIALAQQKIPMLVDQGENDNFLEEQLKPHSLVV
AASSNHYPLSLNMRQGYDHSYYFIASFIETHLYFHAANLGLTE
>Mature_282_residues
SIENISTNKVFDGWHKQYNHQSQTLNCKMRFAIYLPPQAANGKKVPVMYWLSGLTCTDENFMQKASALKLAAELGIAIVA
PDTSPRGEGVADDPEQAYDLGLGAGFYVNATQAPWNKHYQMYDYVVNELPGIIENHFPVNKQRVISGHSMGGHGALMIAL
RNPSLYQSATAFSPVSNPVNCPWGKKAFSAYLGADSKKWLQYDTCELIALAQQKIPMLVDQGENDNFLEEQLKPHSLVVA
ASSNHYPLSLNMRQGYDHSYYFIASFIETHLYFHAANLGLTE

Specific function: Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate [H]

COG id: COG0627

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the esterase D family [H]

Homologues:

Organism=Homo sapiens, GI33413400, Length=282, Percent_Identity=50.709219858156, Blast_Score=307, Evalue=9e-84,
Organism=Escherichia coli, GI1788477, Length=279, Percent_Identity=55.5555555555556, Blast_Score=326, Evalue=1e-90,
Organism=Escherichia coli, GI1786551, Length=279, Percent_Identity=50.8960573476703, Blast_Score=302, Evalue=2e-83,
Organism=Caenorhabditis elegans, GI17510185, Length=283, Percent_Identity=45.9363957597173, Blast_Score=246, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6322393, Length=281, Percent_Identity=43.7722419928826, Blast_Score=232, Evalue=6e-62,
Organism=Drosophila melanogaster, GI45551932, Length=284, Percent_Identity=49.2957746478873, Blast_Score=288, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24648347, Length=283, Percent_Identity=49.1166077738516, Blast_Score=288, Evalue=3e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801
- InterPro:   IPR014186 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: =3.1.2.12 [H]

Molecular weight: Translated: 31543; Mature: 31412

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIENISTNKVFDGWHKQYNHQSQTLNCKMRFAIYLPPQAANGKKVPVMYWLSGLTCTDE
CCCCCCCCCCHHCCHHHHHCCCCCEEEEEEEEEEEECCCCCCCCCCEEEEEECCCEECCH
NFMQKASALKLAAELGIAIVAPDTSPRGEGVADDPEQAYDLGLGAGFYVNATQAPWNKHY
HHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCHHHHHHHCCCCCEEEECCCCCCHHHH
QMYDYVVNELPGIIENHFPVNKQRVISGHSMGGHGALMIALRNPSLYQSATAFSPVSNPV
HHHHHHHHHCCHHHHCCCCCCHHEEEECCCCCCCCEEEEEEECCCHHHHHHCCCCCCCCC
NCPWGKKAFSAYLGADSKKWLQYDTCELIALAQQKIPMLVDQGENDNFLEEQLKPHSLVV
CCCCCHHHHHHHHCCCCCHHEECCHHHHHHHHHHCCCEEEECCCCCCHHHHHCCCCEEEE
AASSNHYPLSLNMRQGYDHSYYFIASFIETHLYFHAANLGLTE
EECCCCCEEEEECCCCCCCCHHHHHHHHHHHHEEEECCCCCCC
>Mature Secondary Structure 
SIENISTNKVFDGWHKQYNHQSQTLNCKMRFAIYLPPQAANGKKVPVMYWLSGLTCTDE
CCCCCCCCCHHCCHHHHHCCCCCEEEEEEEEEEEECCCCCCCCCCEEEEEECCCEECCH
NFMQKASALKLAAELGIAIVAPDTSPRGEGVADDPEQAYDLGLGAGFYVNATQAPWNKHY
HHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCHHHHHHHCCCCCEEEECCCCCCHHHH
QMYDYVVNELPGIIENHFPVNKQRVISGHSMGGHGALMIALRNPSLYQSATAFSPVSNPV
HHHHHHHHHCCHHHHCCCCCCHHEEEECCCCCCCCEEEEEEECCCHHHHHHCCCCCCCCC
NCPWGKKAFSAYLGADSKKWLQYDTCELIALAQQKIPMLVDQGENDNFLEEQLKPHSLVV
CCCCCHHHHHHHHCCCCCHHEECCHHHHHHHHHHCCCEEEECCCCCCHHHHHCCCCEEEE
AASSNHYPLSLNMRQGYDHSYYFIASFIETHLYFHAANLGLTE
EECCCCCEEEEECCCCCCCCHHHHHHHHHHHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA