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The map label for this gene is glpG [H]

Identifier: 119947069

GI number: 119947069

Start: 4287722

End: 4288564

Strand: Direct

Name: glpG [H]

Synonym: Ping_3467

Alternate gene names: 119947069

Gene position: 4287722-4288564 (Clockwise)

Preceding gene: 119947068

Following gene: 119947070

Centisome position: 94.04

GC content: 39.26

Gene sequence:

>843_bases
ATGTTTTTACTGCATCAATTTCAAAACGAACGTGCTGCACAAGCATTTTCTGATTATTTAAGTGCTATTGGTATTAAAAA
CAACCTTCATCATGACGACTTTAGCTATCAATTATTGATTGAACAAAAAGAGCAGCAGACGCAGGCTGAAATTGAGCTGG
ATCTGTTTTTACAGCATCCCAATGATCCTAAATATATGTCGGCAAGCTGGCAAACCGGTGAGGTAAGCAGTGAAAATAAC
TATTTCGCTTTTGCTGACTCGAATTTAGTCAGCAATTTTATCCATCATGCGGGGTTAGTGACTCATAGTATTTTTGCTGT
CTGTTTAGTTATTTACCTGCTGATAGCATCTGGGGTGTTTCAACCAATCCCTTCTGTATTGTCTTTTTTTAGTCAGCAAC
CCTTTGATTATTTACAGAGTTGGCGTTTTATTACCCCAGCGTTATTACATTTCAGCGCACTGCACATTATTTTTAATTTA
CTGTGGTGGTGGCAATTAGCCGGTCTTGTTGAAAAACAGCAGGGTAAAATGCACTTGCTGGTGCTTTTCCTGTTTTCAGG
AATCGCTGCTAATCTGGCGCAATATTTTTTAGTCAGCCCTTATTTTGGCGGATTAAGCGGTGTTGTTTATGGGTTAGTGG
GTTATTGCTGGTTATTTGGCAAGCTCAATAAAAGCAGTCAAGTAATGTTGCCCGATGCTTATTTTGTCTTTTTACTCGCC
TGGCTGGTTTTAGGTTTTGTGGATCTGTTACCGGTAAATATTGCTAACTATGCGCATCTGGTGGGGTTATTAGCGGGTTT
ATTAATGGCGGTTCTGACCAGTAAACTAAGGTTACATGTTTAA

Upstream 100 bases:

>100_bases
AGATGGGTTAGAACGTTCGATGTTATTGCTTAAGATTTTAAATCAGGATAATAATATTTCATTCAAAAATTCAGCTCTAA
AAAAAGTGGAAAGCTAACCT

Downstream 100 bases:

>100_bases
CCTACGGGGCTACCACAGAGGTCGCAGAGGCGCTACGCGCTACACAGAGGAATGACTAAAATAGTGGTTACTAAGTTTTT
TGGGGTTTCCTTCTTAACTC

Product: membrane serine peptidase

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MFLLHQFQNERAAQAFSDYLSAIGIKNNLHHDDFSYQLLIEQKEQQTQAEIELDLFLQHPNDPKYMSASWQTGEVSSENN
YFAFADSNLVSNFIHHAGLVTHSIFAVCLVIYLLIASGVFQPIPSVLSFFSQQPFDYLQSWRFITPALLHFSALHIIFNL
LWWWQLAGLVEKQQGKMHLLVLFLFSGIAANLAQYFLVSPYFGGLSGVVYGLVGYCWLFGKLNKSSQVMLPDAYFVFLLA
WLVLGFVDLLPVNIANYAHLVGLLAGLLMAVLTSKLRLHV

Sequences:

>Translated_280_residues
MFLLHQFQNERAAQAFSDYLSAIGIKNNLHHDDFSYQLLIEQKEQQTQAEIELDLFLQHPNDPKYMSASWQTGEVSSENN
YFAFADSNLVSNFIHHAGLVTHSIFAVCLVIYLLIASGVFQPIPSVLSFFSQQPFDYLQSWRFITPALLHFSALHIIFNL
LWWWQLAGLVEKQQGKMHLLVLFLFSGIAANLAQYFLVSPYFGGLSGVVYGLVGYCWLFGKLNKSSQVMLPDAYFVFLLA
WLVLGFVDLLPVNIANYAHLVGLLAGLLMAVLTSKLRLHV
>Mature_280_residues
MFLLHQFQNERAAQAFSDYLSAIGIKNNLHHDDFSYQLLIEQKEQQTQAEIELDLFLQHPNDPKYMSASWQTGEVSSENN
YFAFADSNLVSNFIHHAGLVTHSIFAVCLVIYLLIASGVFQPIPSVLSFFSQQPFDYLQSWRFITPALLHFSALHIIFNL
LWWWQLAGLVEKQQGKMHLLVLFLFSGIAANLAQYFLVSPYFGGLSGVVYGLVGYCWLFGKLNKSSQVMLPDAYFVFLLA
WLVLGFVDLLPVNIANYAHLVGLLAGLLMAVLTSKLRLHV

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

Organism=Escherichia coli, GI48994938, Length=277, Percent_Identity=37.1841155234657, Blast_Score=182, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022732
- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF12122 DUF3582; PF01694 Rhomboid [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 31741; Mature: 31741

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLLHQFQNERAAQAFSDYLSAIGIKNNLHHDDFSYQLLIEQKEQQTQAEIELDLFLQHP
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHEEHEEEEECC
NDPKYMSASWQTGEVSSENNYFAFADSNLVSNFIHHAGLVTHSIFAVCLVIYLLIASGVF
CCCCEEECCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QPIPSVLSFFSQQPFDYLQSWRFITPALLHFSALHIIFNLLWWWQLAGLVEKQQGKMHLL
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
VLFLFSGIAANLAQYFLVSPYFGGLSGVVYGLVGYCWLFGKLNKSSQVMLPDAYFVFLLA
HHHHHHHHHHHHHHHHHHCCHHCHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHH
WLVLGFVDLLPVNIANYAHLVGLLAGLLMAVLTSKLRLHV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFLLHQFQNERAAQAFSDYLSAIGIKNNLHHDDFSYQLLIEQKEQQTQAEIELDLFLQHP
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHEEHEEEEECC
NDPKYMSASWQTGEVSSENNYFAFADSNLVSNFIHHAGLVTHSIFAVCLVIYLLIASGVF
CCCCEEECCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QPIPSVLSFFSQQPFDYLQSWRFITPALLHFSALHIIFNLLWWWQLAGLVEKQQGKMHLL
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
VLFLFSGIAANLAQYFLVSPYFGGLSGVVYGLVGYCWLFGKLNKSSQVMLPDAYFVFLLA
HHHHHHHHHHHHHHHHHHCCHHCHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHH
WLVLGFVDLLPVNIANYAHLVGLLAGLLMAVLTSKLRLHV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA