Click here to switch to the map view.

The map label for this gene is rnr [H]

Identifier: 119947020

GI number: 119947020

Start: 4222506

End: 4225010

Strand: Direct

Name: rnr [H]

Synonym: Ping_3417

Alternate gene names: 119947020

Gene position: 4222506-4225010 (Clockwise)

Preceding gene: 119947019

Following gene: 119947021

Centisome position: 92.61

GC content: 43.83

Gene sequence:

>2505_bases
ATGACCCAAGACCCCTTCCTAGATCGCGAAGCGCAAACTTACGAGCATCCAGTGCCAAGTCGTGAATTTATTTTAGAATA
TTTAGAAAAACAAGCAAAACCTATTAGCCGTGATGCCCTGTTTAACGCTTTTTCTTTAAGCGGTGAAGAGGAAGCCGAGG
GGTTGCGTCGTCGTTTAAAAGCGATGGAACGTGATGGGCAATTAGTCTGGTGCCGTAATGCGACTTATGCACTCCCGGAC
AAATTGAATCTAATTAAAGGTAAAGTGATTGGCCACAAAGATGGTTTTGGTTTTTTGAAAACTGAAGAAGAAGGTGCCGA
TCTTTTTTTACCCGCACATCAAATGCGTTTACTCTTTCACGGCGATAAAGTCCTTGTCCAACCGGTTAAAGTTGATTCGC
GAGGTCGCACCGAAGCGCGTTTTGTACGTTTATTAGAAGAACGTAAAGAACCTATTGTCGGCCGTTATTTTGTCGAAGAC
GGCATCGCTGTCGTGGTGCCCGATGATTCTCGCATCAATCAAGATATTCTCATCAATCAAGATAACAATCTCGGTGCCCG
CCACGGACAAATAGTCGTAGTGGAAATTCTCCAGCGTCCAAAACCTCGTTTGACTGCAAAAGGTAAAATCACTGAAATAC
TGGGTCAAGATATGGAACCCGGTATGGAAGTTGAGGTTGCACTGCGTACTCATGATATCCCGCATCAATGGCCTGAAGGT
TTAGACAAAGAATTAGAAAACTTTACTGAAACTGTGCCTGAAGAAGCGATACAAGGGCGTGTAGATTTACGCCAATTACC
ACTGGTCACAATAGATGGCGAAGATGCGCGCGATTTTGATGATGCGGTTTTCTGTAAAGCTGAAGCCGGTGGCGGCTGGC
GTCTGTGGGTAGCTATTGCAGACGTAAGCTATTACGTTCGACCCGGTACTATTTTAGATAAAGAAGCGATTAATCGTGGT
AACTCGGTCTATTTCCCCGACCAGGTTGTGCCTATGTTGCCGGAAATATTATCTAATGGATTGTGCTCGTTAAATCCGCA
GGTCGATCGTTTATGTATGGTCAGTGAAATGGTTATTTCTAAAGCCGGACTGCTCACGGATTACAAATTCTATGAAGCAG
TAATGAATTCTCATGCACGCTTTACTTATACTAAAGTAGCGGCCATTTTAGAGGGTGATCAGACACTGCGCGAGCAGTAC
AAACCTTTAGTGCCTCATATCGAAGAGTTAGAGCACCTTTATAAAGCCTTCAAGCGCGCACGCAAGATTCGAGGTGGAAT
GGAGTTTGAAACCTTAGAAACGCGTTTTATTTTTGATCAAAACCGTAAAATAGAATCTATCGAGCCAATAACACGTAACG
ATGCGCATAAGATCATAGAAGAATGCATGATTCAGGCAAACGTTGCTTCGGCACGTTTAATTGGCAAGGCAGAAGCTGCT
GCGTTATACCGCGTTCATGAAACTCCCAGTCAGGAAAAATTAGTTAACTTCCGTTCATTTTTGTCAGAGCTTGGTTTAAG
CCTTGCCGGTGGAGAGAAACCGGCACCGCGTGATTATGCGGCATTAGCTGAAGAATTTGCGGGTCGTGAAGACAGTGAGC
TTTTACAAACCATGTTATTACGCTCAATGAAACAAGCTGTCTATCAAGATGAAAATCTCGGACACTTTGGCTTGGCGTTA
GAAGAGTACGCTCACTTCACCTCTCCTATTCGTCGTTACCCGGATCTGATTTTACACCGTGCCATTAAATATTTAATCGA
ACATCAGGCAAAGGGTCAGTTGAAATCAAAATGGACCAATACCGGCGGATATCATTATCTACATGAAGAGATGGGTGCCT
TAGGCGAGCATTGTTCAATGACTGAACGCCGCGCCGATGATGCCACTCGTGATGTAGGTGACGCTTTAAAATGTGAATAT
ATGCAGGATCATGTTGGTGATGTAATGCACGGCACTATTGCCGCTGTCACCAACTTTGGTTTCTTTGTACGCTTAACGGG
TATTCAAATCGATGGCTTGGTCCATGTGACAAGCTTACTGTCTGATTATTATATCTTTGATGCAGGCAAACAAACCCTTA
AAGGTGAGCGTACGGGACGTACCTTTAGGATCGGTGATGCATTAGATGTGAAAGTGTTGTCAGTTAATTTAGATGATAAA
AAAATCGATTTTGAATTAGCGGATCAAGCGGCAGCGGGACAACGAAAACGAGCTCAAAATACGGCCGCGCGTGAAAACGA
TCGCCCGATAGATAAACGGGCACGGTCAAAAGCGGCGGGCAAAGGTCGCGCAAATGATAACGCTAAAAAAAGCGATCAGC
CGGTTGAAAAAGAACCCGCTAAGCAAGAGCAAAAAGCCAACAAGCCCAAAAGAAAAAGAACGATAAAACAGGGCGAAAAA
AACACCGCATCATCAAAAACAAAAAAAACCACGGCAACAGCTAAAAAAGTAGGTCGTGCTGATCGCCGTAATAAAATAAA
ACAAGCAAACAAAATAAATAGCTAA

Upstream 100 bases:

>100_bases
TTTTTTATTGTAAATAACCTCTCACGGGAACATTAATCAGACGATTTCCGTATTTTCAGATATACTTTCAATAATTTACC
CACAAATAGAGTCTTCAATT

Downstream 100 bases:

>100_bases
CAGCTAGGAGCTACGAGCGGCGAGCTAGGAGATACAAGCTTTCTAGCTTTCAGGCGTTCGAGCTGCGAGTCTTGAGCTAT
TATCAACAAATAGAATTAGA

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 834; Mature: 833

Protein sequence:

>834_residues
MTQDPFLDREAQTYEHPVPSREFILEYLEKQAKPISRDALFNAFSLSGEEEAEGLRRRLKAMERDGQLVWCRNATYALPD
KLNLIKGKVIGHKDGFGFLKTEEEGADLFLPAHQMRLLFHGDKVLVQPVKVDSRGRTEARFVRLLEERKEPIVGRYFVED
GIAVVVPDDSRINQDILINQDNNLGARHGQIVVVEILQRPKPRLTAKGKITEILGQDMEPGMEVEVALRTHDIPHQWPEG
LDKELENFTETVPEEAIQGRVDLRQLPLVTIDGEDARDFDDAVFCKAEAGGGWRLWVAIADVSYYVRPGTILDKEAINRG
NSVYFPDQVVPMLPEILSNGLCSLNPQVDRLCMVSEMVISKAGLLTDYKFYEAVMNSHARFTYTKVAAILEGDQTLREQY
KPLVPHIEELEHLYKAFKRARKIRGGMEFETLETRFIFDQNRKIESIEPITRNDAHKIIEECMIQANVASARLIGKAEAA
ALYRVHETPSQEKLVNFRSFLSELGLSLAGGEKPAPRDYAALAEEFAGREDSELLQTMLLRSMKQAVYQDENLGHFGLAL
EEYAHFTSPIRRYPDLILHRAIKYLIEHQAKGQLKSKWTNTGGYHYLHEEMGALGEHCSMTERRADDATRDVGDALKCEY
MQDHVGDVMHGTIAAVTNFGFFVRLTGIQIDGLVHVTSLLSDYYIFDAGKQTLKGERTGRTFRIGDALDVKVLSVNLDDK
KIDFELADQAAAGQRKRAQNTAARENDRPIDKRARSKAAGKGRANDNAKKSDQPVEKEPAKQEQKANKPKRKRTIKQGEK
NTASSKTKKTTATAKKVGRADRRNKIKQANKINS

Sequences:

>Translated_834_residues
MTQDPFLDREAQTYEHPVPSREFILEYLEKQAKPISRDALFNAFSLSGEEEAEGLRRRLKAMERDGQLVWCRNATYALPD
KLNLIKGKVIGHKDGFGFLKTEEEGADLFLPAHQMRLLFHGDKVLVQPVKVDSRGRTEARFVRLLEERKEPIVGRYFVED
GIAVVVPDDSRINQDILINQDNNLGARHGQIVVVEILQRPKPRLTAKGKITEILGQDMEPGMEVEVALRTHDIPHQWPEG
LDKELENFTETVPEEAIQGRVDLRQLPLVTIDGEDARDFDDAVFCKAEAGGGWRLWVAIADVSYYVRPGTILDKEAINRG
NSVYFPDQVVPMLPEILSNGLCSLNPQVDRLCMVSEMVISKAGLLTDYKFYEAVMNSHARFTYTKVAAILEGDQTLREQY
KPLVPHIEELEHLYKAFKRARKIRGGMEFETLETRFIFDQNRKIESIEPITRNDAHKIIEECMIQANVASARLIGKAEAA
ALYRVHETPSQEKLVNFRSFLSELGLSLAGGEKPAPRDYAALAEEFAGREDSELLQTMLLRSMKQAVYQDENLGHFGLAL
EEYAHFTSPIRRYPDLILHRAIKYLIEHQAKGQLKSKWTNTGGYHYLHEEMGALGEHCSMTERRADDATRDVGDALKCEY
MQDHVGDVMHGTIAAVTNFGFFVRLTGIQIDGLVHVTSLLSDYYIFDAGKQTLKGERTGRTFRIGDALDVKVLSVNLDDK
KIDFELADQAAAGQRKRAQNTAARENDRPIDKRARSKAAGKGRANDNAKKSDQPVEKEPAKQEQKANKPKRKRTIKQGEK
NTASSKTKKTTATAKKVGRADRRNKIKQANKINS
>Mature_833_residues
TQDPFLDREAQTYEHPVPSREFILEYLEKQAKPISRDALFNAFSLSGEEEAEGLRRRLKAMERDGQLVWCRNATYALPDK
LNLIKGKVIGHKDGFGFLKTEEEGADLFLPAHQMRLLFHGDKVLVQPVKVDSRGRTEARFVRLLEERKEPIVGRYFVEDG
IAVVVPDDSRINQDILINQDNNLGARHGQIVVVEILQRPKPRLTAKGKITEILGQDMEPGMEVEVALRTHDIPHQWPEGL
DKELENFTETVPEEAIQGRVDLRQLPLVTIDGEDARDFDDAVFCKAEAGGGWRLWVAIADVSYYVRPGTILDKEAINRGN
SVYFPDQVVPMLPEILSNGLCSLNPQVDRLCMVSEMVISKAGLLTDYKFYEAVMNSHARFTYTKVAAILEGDQTLREQYK
PLVPHIEELEHLYKAFKRARKIRGGMEFETLETRFIFDQNRKIESIEPITRNDAHKIIEECMIQANVASARLIGKAEAAA
LYRVHETPSQEKLVNFRSFLSELGLSLAGGEKPAPRDYAALAEEFAGREDSELLQTMLLRSMKQAVYQDENLGHFGLALE
EYAHFTSPIRRYPDLILHRAIKYLIEHQAKGQLKSKWTNTGGYHYLHEEMGALGEHCSMTERRADDATRDVGDALKCEYM
QDHVGDVMHGTIAAVTNFGFFVRLTGIQIDGLVHVTSLLSDYYIFDAGKQTLKGERTGRTFRIGDALDVKVLSVNLDDKK
IDFELADQAAAGQRKRAQNTAARENDRPIDKRARSKAAGKGRANDNAKKSDQPVEKEPAKQEQKANKPKRKRTIKQGEKN
TASSKTKKTTATAKKVGRADRRNKIKQANKINS

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=409, Percent_Identity=30.3178484107579, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI190014625, Length=409, Percent_Identity=30.3178484107579, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI134288890, Length=490, Percent_Identity=28.9795918367347, Blast_Score=175, Evalue=2e-43,
Organism=Homo sapiens, GI19115966, Length=516, Percent_Identity=26.5503875968992, Blast_Score=155, Evalue=2e-37,
Organism=Homo sapiens, GI219521928, Length=516, Percent_Identity=26.5503875968992, Blast_Score=154, Evalue=3e-37,
Organism=Escherichia coli, GI87082383, Length=726, Percent_Identity=62.9476584022039, Blast_Score=960, Evalue=0.0,
Organism=Escherichia coli, GI1787542, Length=649, Percent_Identity=26.502311248074, Blast_Score=175, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI17553506, Length=420, Percent_Identity=30.2380952380952, Blast_Score=169, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI212645896, Length=424, Percent_Identity=29.9528301886792, Blast_Score=161, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6324552, Length=576, Percent_Identity=27.6041666666667, Blast_Score=146, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24649634, Length=417, Percent_Identity=30.6954436450839, Blast_Score=166, Evalue=6e-41,
Organism=Drosophila melanogaster, GI19922976, Length=361, Percent_Identity=28.5318559556787, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24654597, Length=361, Percent_Identity=28.5318559556787, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24654592, Length=361, Percent_Identity=28.5318559556787, Blast_Score=127, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 94263; Mature: 94132

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDPFLDREAQTYEHPVPSREFILEYLEKQAKPISRDALFNAFSLSGEEEAEGLRRRLK
CCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHH
AMERDGQLVWCRNATYALPDKLNLIKGKVIGHKDGFGFLKTEEEGADLFLPAHQMRLLFH
HHHCCCCEEEECCCCCCCCCCCHHHHCEEEECCCCCCCEEECCCCCCEEECHHHEEEEEE
GDKVLVQPVKVDSRGRTEARFVRLLEERKEPIVGRYFVEDGIAVVVPDDSRINQDILINQ
CCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCEEEEC
DNNLGARHGQIVVVEILQRPKPRLTAKGKITEILGQDMEPGMEVEVALRTHDIPHQWPEG
CCCCCCCCCCEEEEEHHHCCCCCCCCCCHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCH
LDKELENFTETVPEEAIQGRVDLRQLPLVTIDGEDARDFDDAVFCKAEAGGGWRLWVAIA
HHHHHHHHHHHCCHHHHCCCCCHHHCCEEEECCCCCCCCCCEEEEEECCCCCEEEEEEEE
DVSYYVRPGTILDKEAINRGNSVYFPDQVVPMLPEILSNGLCSLNPQVDRLCMVSEMVIS
CCEEEECCCCEECHHHHCCCCCEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
KAGLLTDYKFYEAVMNSHARFTYTKVAAILEGDQTLREQYKPLVPHIEELEHLYKAFKRA
HHCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHH
RKIRGGMEFETLETRFIFDQNRKIESIEPITRNDAHKIIEECMIQANVASARLIGKAEAA
HHHHCCCCCHHHHEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
ALYRVHETPSQEKLVNFRSFLSELGLSLAGGEKPAPRDYAALAEEFAGREDSELLQTMLL
HHHHHHCCCCHHHHHHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHH
RSMKQAVYQDENLGHFGLALEEYAHFTSPIRRYPDLILHRAIKYLIEHQAKGQLKSKWTN
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
TGGYHYLHEEMGALGEHCSMTERRADDATRDVGDALKCEYMQDHVGDVMHGTIAAVTNFG
CCCEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FFVRLTGIQIDGLVHVTSLLSDYYIFDAGKQTLKGERTGRTFRIGDALDVKVLSVNLDDK
EEEEEECEEECHHHHHHHHHHHHHEEECCHHHHCCCCCCCEEEECCCCEEEEEEEECCCC
KIDFELADQAAAGQRKRAQNTAARENDRPIDKRARSKAAGKGRANDNAKKSDQPVEKEPA
EECHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCH
KQEQKANKPKRKRTIKQGEKNTASSKTKKTTATAKKVGRADRRNKIKQANKINS
HHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TQDPFLDREAQTYEHPVPSREFILEYLEKQAKPISRDALFNAFSLSGEEEAEGLRRRLK
CCCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHH
AMERDGQLVWCRNATYALPDKLNLIKGKVIGHKDGFGFLKTEEEGADLFLPAHQMRLLFH
HHHCCCCEEEECCCCCCCCCCCHHHHCEEEECCCCCCCEEECCCCCCEEECHHHEEEEEE
GDKVLVQPVKVDSRGRTEARFVRLLEERKEPIVGRYFVEDGIAVVVPDDSRINQDILINQ
CCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCEEEEC
DNNLGARHGQIVVVEILQRPKPRLTAKGKITEILGQDMEPGMEVEVALRTHDIPHQWPEG
CCCCCCCCCCEEEEEHHHCCCCCCCCCCHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCH
LDKELENFTETVPEEAIQGRVDLRQLPLVTIDGEDARDFDDAVFCKAEAGGGWRLWVAIA
HHHHHHHHHHHCCHHHHCCCCCHHHCCEEEECCCCCCCCCCEEEEEECCCCCEEEEEEEE
DVSYYVRPGTILDKEAINRGNSVYFPDQVVPMLPEILSNGLCSLNPQVDRLCMVSEMVIS
CCEEEECCCCEECHHHHCCCCCEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
KAGLLTDYKFYEAVMNSHARFTYTKVAAILEGDQTLREQYKPLVPHIEELEHLYKAFKRA
HHCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHH
RKIRGGMEFETLETRFIFDQNRKIESIEPITRNDAHKIIEECMIQANVASARLIGKAEAA
HHHHCCCCCHHHHEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
ALYRVHETPSQEKLVNFRSFLSELGLSLAGGEKPAPRDYAALAEEFAGREDSELLQTMLL
HHHHHHCCCCHHHHHHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHH
RSMKQAVYQDENLGHFGLALEEYAHFTSPIRRYPDLILHRAIKYLIEHQAKGQLKSKWTN
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
TGGYHYLHEEMGALGEHCSMTERRADDATRDVGDALKCEYMQDHVGDVMHGTIAAVTNFG
CCCEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FFVRLTGIQIDGLVHVTSLLSDYYIFDAGKQTLKGERTGRTFRIGDALDVKVLSVNLDDK
EEEEEECEEECHHHHHHHHHHHHHEEECCHHHHCCCCCCCEEEECCCCEEEEEEEECCCC
KIDFELADQAAAGQRKRAQNTAARENDRPIDKRARSKAAGKGRANDNAKKSDQPVEKEPA
EECHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCH
KQEQKANKPKRKRTIKQGEKNTASSKTKKTTATAKKVGRADRRNKIKQANKINS
HHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]