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The map label for this gene is ackA [H]

Identifier: 119946917

GI number: 119946917

Start: 4083031

End: 4084245

Strand: Direct

Name: ackA [H]

Synonym: Ping_3311

Alternate gene names: 119946917

Gene position: 4083031-4084245 (Clockwise)

Preceding gene: 119946915

Following gene: 119946918

Centisome position: 89.55

GC content: 43.29

Gene sequence:

>1215_bases
ATGAATAACAAACTGGTACTTGTCCTTAACTGTGGCAGCTCATCTCTTAAATTCGCGGTTATCAATGCTGATAACGGTGG
TGAGATAATGAGTGGTCTTGCTGAATGTTTTAATCTTCCCGAGGCACGTATCAAATGGAAAATGGCAGGAACAAAAAAGT
CCACCAGTCTTCCCCCTTATAGCGCACACTCTGCAGCAATATCTTTTATTGTAGAAGAGATTATTAAAAAAGAAGCAGGC
TTAACTGAGCAGTTTGTAGCCGTCGGTCACCGCATTGTTCATGGTGGCGAAAGATTTACAGAATCAGTTATTATTGATGA
CCATGTACTTGAAGGTATTGAACAGTGCTCATCCCTTGCTCCACTGCATAATCCGGCCCATGCGCTAGGTATTCGAGCAG
CGCAGGTCGCTTTCCCGGCGCTTCCACAGGTTGCCGTATTTGATACTGCATTCCATCAAACTATGCCTGCTAAAGCGTTT
ATGTATGCACTGCCCTATCATTTATACAAAGAGTACAGCATCCGCCGTTACGGTATGCACGGAACAAGTAATCTGTTCGT
TACCCATGAAGCCGCAAAAATATTAAACAAACCCGTCGATGATCTCAACGTTATCTGCGCGCATTTAGGTAATGGTGCAT
CGGTGACTGCCATTAAAAAGGGTCAAAGTGTCGATACCAGTATGGGGCTAACACCGCTGGATGGTTTAGTAATGGGAACA
CGTTGTGGTGATCTTGACCCGAGTATTATTGAATACTTAATAACTCGTCTGGGTTACAGCATCGAAGGCGTCATGGAAAT
ATTACAAAAACAAAGTGGTTTGCTTGGCATTTCCGGTATTTCCAGCGATTTCCGTGAAATTATTGCAGGCTATGAGCAAG
GTAGCAAAAGAGCGACACTCGCAATAGACATGTTTATCTACCGCCTTGCCAAATATATTGCTTCTTACGCTGTACCATTA
GGCCATATTGATGCCATTATTTTCACTGGCGGGATCGGTGAAAATTCCCCCCTTGTCCGCAGCAAGGTATTGGAATTATT
AACCATTTTTGGTTACCAAGTCGACGGCGAAAAAAATAAAGCCGCGATATTGGGCAATCAAGGTATAATTACGATAGCCG
GCTCCCCGATTGCGATGGTTATCCCTACCAATGAAGAGTGGGTCATTGCACAAGATTCTGCAAAACTAGTTTCAAATCAA
TCATTATCACTATAA

Upstream 100 bases:

>100_bases
ACACAATTATGCGATCTGAGTCACTAATTGGCATGGCTTTTTTGACCATCAAGCACATAACATTGATCGACTATTTCAAA
CTTTACTTACTGGGTTTTTC

Downstream 100 bases:

>100_bases
ATAGGGGAAAAACACTCCCCACTTTTTCCTCTAATTTCTTTATTTACAAGGAATAGTCATGCCCCGCACAATTATGCTCA
TTCCCATCGGTTCCGGTGTT

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MNNKLVLVLNCGSSSLKFAVINADNGGEIMSGLAECFNLPEARIKWKMAGTKKSTSLPPYSAHSAAISFIVEEIIKKEAG
LTEQFVAVGHRIVHGGERFTESVIIDDHVLEGIEQCSSLAPLHNPAHALGIRAAQVAFPALPQVAVFDTAFHQTMPAKAF
MYALPYHLYKEYSIRRYGMHGTSNLFVTHEAAKILNKPVDDLNVICAHLGNGASVTAIKKGQSVDTSMGLTPLDGLVMGT
RCGDLDPSIIEYLITRLGYSIEGVMEILQKQSGLLGISGISSDFREIIAGYEQGSKRATLAIDMFIYRLAKYIASYAVPL
GHIDAIIFTGGIGENSPLVRSKVLELLTIFGYQVDGEKNKAAILGNQGIITIAGSPIAMVIPTNEEWVIAQDSAKLVSNQ
SLSL

Sequences:

>Translated_404_residues
MNNKLVLVLNCGSSSLKFAVINADNGGEIMSGLAECFNLPEARIKWKMAGTKKSTSLPPYSAHSAAISFIVEEIIKKEAG
LTEQFVAVGHRIVHGGERFTESVIIDDHVLEGIEQCSSLAPLHNPAHALGIRAAQVAFPALPQVAVFDTAFHQTMPAKAF
MYALPYHLYKEYSIRRYGMHGTSNLFVTHEAAKILNKPVDDLNVICAHLGNGASVTAIKKGQSVDTSMGLTPLDGLVMGT
RCGDLDPSIIEYLITRLGYSIEGVMEILQKQSGLLGISGISSDFREIIAGYEQGSKRATLAIDMFIYRLAKYIASYAVPL
GHIDAIIFTGGIGENSPLVRSKVLELLTIFGYQVDGEKNKAAILGNQGIITIAGSPIAMVIPTNEEWVIAQDSAKLVSNQ
SLSL
>Mature_404_residues
MNNKLVLVLNCGSSSLKFAVINADNGGEIMSGLAECFNLPEARIKWKMAGTKKSTSLPPYSAHSAAISFIVEEIIKKEAG
LTEQFVAVGHRIVHGGERFTESVIIDDHVLEGIEQCSSLAPLHNPAHALGIRAAQVAFPALPQVAVFDTAFHQTMPAKAF
MYALPYHLYKEYSIRRYGMHGTSNLFVTHEAAKILNKPVDDLNVICAHLGNGASVTAIKKGQSVDTSMGLTPLDGLVMGT
RCGDLDPSIIEYLITRLGYSIEGVMEILQKQSGLLGISGISSDFREIIAGYEQGSKRATLAIDMFIYRLAKYIASYAVPL
GHIDAIIFTGGIGENSPLVRSKVLELLTIFGYQVDGEKNKAAILGNQGIITIAGSPIAMVIPTNEEWVIAQDSAKLVSNQ
SLSL

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788633, Length=403, Percent_Identity=57.0719602977667, Blast_Score=471, Evalue=1e-134,
Organism=Escherichia coli, GI145693184, Length=393, Percent_Identity=45.5470737913486, Blast_Score=346, Evalue=2e-96,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 43505; Mature: 43505

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKLVLVLNCGSSSLKFAVINADNGGEIMSGLAECFNLPEARIKWKMAGTKKSTSLPPY
CCCCEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHCCCCHHEEEEECCCCCCCCCCCC
SAHSAAISFIVEEIIKKEAGLTEQFVAVGHRIVHGGERFTESVIIDDHVLEGIEQCSSLA
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHEEECHHHHHHHHHHHHCC
PLHNPAHALGIRAAQVAFPALPQVAVFDTAFHQTMPAKAFMYALPYHLYKEYSIRRYGMH
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEECCC
GTSNLFVTHEAAKILNKPVDDLNVICAHLGNGASVTAIKKGQSVDTSMGLTPLDGLVMGT
CCCCEEEEHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEC
RCGDLDPSIIEYLITRLGYSIEGVMEILQKQSGLLGISGISSDFREIIAGYEQGSKRATL
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHCCCCEEEH
AIDMFIYRLAKYIASYAVPLGHIDAIIFTGGIGENSPLVRSKVLELLTIFGYQVDGEKNK
HHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCEEECCCCCC
AAILGNQGIITIAGSPIAMVIPTNEEWVIAQDSAKLVSNQSLSL
EEEECCCCEEEECCCCEEEEEECCCCEEEECCCHHHHCCCCCCC
>Mature Secondary Structure
MNNKLVLVLNCGSSSLKFAVINADNGGEIMSGLAECFNLPEARIKWKMAGTKKSTSLPPY
CCCCEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHCCCCHHEEEEECCCCCCCCCCCC
SAHSAAISFIVEEIIKKEAGLTEQFVAVGHRIVHGGERFTESVIIDDHVLEGIEQCSSLA
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHEEECHHHHHHHHHHHHCC
PLHNPAHALGIRAAQVAFPALPQVAVFDTAFHQTMPAKAFMYALPYHLYKEYSIRRYGMH
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEECCC
GTSNLFVTHEAAKILNKPVDDLNVICAHLGNGASVTAIKKGQSVDTSMGLTPLDGLVMGT
CCCCEEEEHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEC
RCGDLDPSIIEYLITRLGYSIEGVMEILQKQSGLLGISGISSDFREIIAGYEQGSKRATL
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHCCCCEEEH
AIDMFIYRLAKYIASYAVPLGHIDAIIFTGGIGENSPLVRSKVLELLTIFGYQVDGEKNK
HHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCEEECCCCCC
AAILGNQGIITIAGSPIAMVIPTNEEWVIAQDSAKLVSNQSLSL
EEEECCCCEEEECCCCEEEEEECCCCEEEECCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA