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The map label for this gene is rraA

Identifier: 119946902

GI number: 119946902

Start: 4068218

End: 4068730

Strand: Direct

Name: rraA

Synonym: Ping_3296

Alternate gene names: 119946902

Gene position: 4068218-4068730 (Clockwise)

Preceding gene: 119946901

Following gene: 119946904

Centisome position: 89.22

GC content: 42.69

Gene sequence:

>513_bases
ATGCATTACAATACTTCCCTCCTTTGCGATATTTACGCTGATACTGTTGATGTTGTTGAACCCCTGTTAACCAATTTTGG
TGGGCGAAACTCTTTTGCCGGAGAAGTTGTCACCATCAAGTGTTTTGAGTCAGTTGGTCTGATTTATAAAGCACTTGAAG
AAAATGGGTTAGGAAAGGTCTTACTGGTCGATGGTGGTGGTTCATTACGCCGTGCTTTAGTTAATGCACACATTGCTGAA
CTTGCTGTTGAAAATGGCTGGGAAGGTATTGTCGTAAACGGCTGTGTACGTGAAGTGGATCTTCTTGAAGATTTAGATAT
AGGTATACAGGCAATCACTGCAATTCCTGTCGGGGCTGAAGATACACAAATAGGAGAGGTCAACTCGCCAGTTAACTTTG
CCGGTGTGACTTTCCTACCTGAAGATATTTTATATGCCGATAGTACCGGTATTATTATTTCGCCGGAGCCGCTCAATGCA
GAGGCATTGACAGAATCAGATGAAATAGCTTAG

Upstream 100 bases:

>100_bases
CAAACTCAAAACTGTTTTTTTCAATGTAAAAACAAGATTGTAAATGAATAAGTTAAGTTTATACTCAGTAATATCATACT
AACCATAGGCGAGCCTGATA

Downstream 100 bases:

>100_bases
CCGATAAATTGTAAAAAAGCCCAATTAATAATAAATCGGGCTTTTAGTTGCTGACATTAACTTAACGTTAAGCACTCTTA
AATAAATTTTCCTGAATTTT

Product: ribonuclease activity regulator protein RraA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MHYNTSLLCDIYADTVDVVEPLLTNFGGRNSFAGEVVTIKCFESVGLIYKALEENGLGKVLLVDGGGSLRRALVNAHIAE
LAVENGWEGIVVNGCVREVDLLEDLDIGIQAITAIPVGAEDTQIGEVNSPVNFAGVTFLPEDILYADSTGIIISPEPLNA
EALTESDEIA

Sequences:

>Translated_170_residues
MHYNTSLLCDIYADTVDVVEPLLTNFGGRNSFAGEVVTIKCFESVGLIYKALEENGLGKVLLVDGGGSLRRALVNAHIAE
LAVENGWEGIVVNGCVREVDLLEDLDIGIQAITAIPVGAEDTQIGEVNSPVNFAGVTFLPEDILYADSTGIIISPEPLNA
EALTESDEIA
>Mature_170_residues
MHYNTSLLCDIYADTVDVVEPLLTNFGGRNSFAGEVVTIKCFESVGLIYKALEENGLGKVLLVDGGGSLRRALVNAHIAE
LAVENGWEGIVVNGCVREVDLLEDLDIGIQAITAIPVGAEDTQIGEVNSPVNFAGVTFLPEDILYADSTGIIISPEPLNA
EALTESDEIA

Specific function: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RraA family

Homologues:

Organism=Escherichia coli, GI1790364, Length=161, Percent_Identity=63.3540372670807, Blast_Score=210, Evalue=3e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RRAA_PSYIN (A1SZR8)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_944582.1
- ProteinModelPortal:   A1SZR8
- SMR:   A1SZR8
- STRING:   A1SZR8
- GeneID:   4625782
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_3296
- eggNOG:   COG0684
- HOGENOM:   HBG668175
- OMA:   QNEWEGI
- PhylomeDB:   A1SZR8
- ProtClustDB:   PRK09372
- BioCyc:   PING357804:PING_3296-MONOMER
- HAMAP:   MF_00471
- InterPro:   IPR005493
- InterPro:   IPR014339
- InterPro:   IPR010203
- Gene3D:   G3DSA:3.50.30.40
- TIGRFAMs:   TIGR01935
- TIGRFAMs:   TIGR02998

Pfam domain/function: PF03737 Methyltransf_6; SSF89562 RNaseE_inh/diMeMenaQ_MeTrfase

EC number: NA

Molecular weight: Translated: 18033; Mature: 18033

Theoretical pI: Translated: 3.72; Mature: 3.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYNTSLLCDIYADTVDVVEPLLTNFGGRNSFAGEVVTIKCFESVGLIYKALEENGLGKV
CCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCEE
LLVDGGGSLRRALVNAHIAELAVENGWEGIVVNGCVREVDLLEDLDIGIQAITAIPVGAE
EEEECCCHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHCCCEEEEEEECCCCC
DTQIGEVNSPVNFAGVTFLPEDILYADSTGIIISPEPLNAEALTESDEIA
CCCCCCCCCCCCCCEEEECCCHHEEECCCCEEECCCCCCHHHCCCCCCCC
>Mature Secondary Structure
MHYNTSLLCDIYADTVDVVEPLLTNFGGRNSFAGEVVTIKCFESVGLIYKALEENGLGKV
CCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCEE
LLVDGGGSLRRALVNAHIAELAVENGWEGIVVNGCVREVDLLEDLDIGIQAITAIPVGAE
EEEECCCHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHCCCEEEEEEECCCCC
DTQIGEVNSPVNFAGVTFLPEDILYADSTGIIISPEPLNAEALTESDEIA
CCCCCCCCCCCCCCEEEECCCHHEEECCCCEEECCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA